Click here to switch to the map view.

The map label for this gene is ybiR [C]

Identifier: 212224609

GI number: 212224609

Start: 1334159

End: 1335436

Strand: Reverse

Name: ybiR [C]

Synonym: TON_1458

Alternate gene names: 212224609

Gene position: 1335436-1334159 (Counterclockwise)

Preceding gene: 212224610

Following gene: 212224608

Centisome position: 72.28

GC content: 52.9

Gene sequence:

>1278_bases
ATGGAGCAGGTGATCATAGCGGTTGCAGTGTTCCTCTTTACATATGCGCTCATAATCAGCGAGAGAGTTCACAGAACTGT
AGCGGCTCTCTTTGGGGCATCGATAGTACTTTTTCTGGGCATTGTCCCATGGGAGATGCTCCCGGAGTACCTTGACCTTG
GAACGCTTCTCCTCCTCATAGGTATGATGATAATCGTCAACACTGCCAAGGCGAGCGGTCTCTTCGAGTTCATAGCGATA
AAAACAGCCAAGTTTGCAAAAGGAAGTCCGATGAAAGTCCTGATCATGTTTTCATTTGTCACAGCTCTTGTAAGCTCTGT
CCTCGATAACGTCACGACGGTTTTGCTGCTCACCCCGATGCTCCTCTACATAACACGCCTCATGGACGTTAACCCAATCC
CGTTCCTCCTGGCGGAGATATTCGCCTCCAACATAGGCGGAACGGCGACTCTCATCGGAGACCCCCCGAACATAATGATA
GGCTCTGCTGCGGGGCTGAGTTTTACCGAGTTCCTCCTGAACATGGGGCCAATAGCTGCCATCGATCTGGCCATCGCACT
TGGAATAATCTACCTCGCCTACAGGAATGAGATGAAGACCAGCAAGGCGAAGAGGGAGAGGATTCTTTCCACCATTGAGA
GGCTAAGGGAGGACGAGGCCATAAGGGACTACACCCTTTTCAAAAAGTCTGTAACCGTGATAATCGGCGTTGTCCTGCTC
TTTTTCGTCCACGACAGGCTGGAGATACCGCCGGCCGTCGTCGCCCTTACCGGAGCCTCGGTTCTGCTCATGTGGAGCAG
GATGGAGCCCACGGAGATACTCGAAAAGATCGAGTGGACGGCGATATTCTTCTTCATGGGGCTGTTCATAATAGTCGGCT
CCCTCGTGGAAACCGGCGTTATCGATGATGTCGCCCAGTGGCTTTTAGGCTACGTTCACACAACCGGCCAGGCGCTCGTG
ATGGTGACCTGGTTCTCGGCGATAGCGTCGGCCATAGTGGACAACATTCCGCTAACGGCCGCCATGATACCGCTCATAAA
GTCGATGGGAACCTCAATGGACGTGTATCCCCTTTGGTGGGCTTTAAGCTTGGGTGCGTGTCTCGGAGGCAATGGCACGG
CCATAGGTGCCTCCGCCAACATAGTTGTCCTTGGTATAGCCTCCCGCGAGGGAGTGAAAATCACCTTCATGGACTTCCTG
AAGATAGGCCTGGTCATAATGTTCACAACGGTTGCTGCTGGCATGGGCCTGCTCTGGATTAGGTACATAGGGGTGTGA

Upstream 100 bases:

>100_bases
CTACGGCTCGGAGATAACCAAGATGTCCCCGCTCAGCCCGGTCGTCCTTAAGATAGTCCAGCACGTGGTTAAGCCAACGA
TAATTTATTAGGTGATGCCG

Downstream 100 bases:

>100_bases
ACGATGAGGATACTCGTGCTCGTTGATGGCTCAAAGTGGAGTCAGAAGGCGGCGCTTCATGCTATCTCGATGGCCAAGAA
AAAGAAGGGTAAGGTCACCC

Product: arsenical pump membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MEQVIIAVAVFLFTYALIISERVHRTVAALFGASIVLFLGIVPWEMLPEYLDLGTLLLLIGMMIIVNTAKASGLFEFIAI
KTAKFAKGSPMKVLIMFSFVTALVSSVLDNVTTVLLLTPMLLYITRLMDVNPIPFLLAEIFASNIGGTATLIGDPPNIMI
GSAAGLSFTEFLLNMGPIAAIDLAIALGIIYLAYRNEMKTSKAKRERILSTIERLREDEAIRDYTLFKKSVTVIIGVVLL
FFVHDRLEIPPAVVALTGASVLLMWSRMEPTEILEKIEWTAIFFFMGLFIIVGSLVETGVIDDVAQWLLGYVHTTGQALV
MVTWFSAIASAIVDNIPLTAAMIPLIKSMGTSMDVYPLWWALSLGACLGGNGTAIGASANIVVLGIASREGVKITFMDFL
KIGLVIMFTTVAAGMGLLWIRYIGV

Sequences:

>Translated_425_residues
MEQVIIAVAVFLFTYALIISERVHRTVAALFGASIVLFLGIVPWEMLPEYLDLGTLLLLIGMMIIVNTAKASGLFEFIAI
KTAKFAKGSPMKVLIMFSFVTALVSSVLDNVTTVLLLTPMLLYITRLMDVNPIPFLLAEIFASNIGGTATLIGDPPNIMI
GSAAGLSFTEFLLNMGPIAAIDLAIALGIIYLAYRNEMKTSKAKRERILSTIERLREDEAIRDYTLFKKSVTVIIGVVLL
FFVHDRLEIPPAVVALTGASVLLMWSRMEPTEILEKIEWTAIFFFMGLFIIVGSLVETGVIDDVAQWLLGYVHTTGQALV
MVTWFSAIASAIVDNIPLTAAMIPLIKSMGTSMDVYPLWWALSLGACLGGNGTAIGASANIVVLGIASREGVKITFMDFL
KIGLVIMFTTVAAGMGLLWIRYIGV
>Mature_425_residues
MEQVIIAVAVFLFTYALIISERVHRTVAALFGASIVLFLGIVPWEMLPEYLDLGTLLLLIGMMIIVNTAKASGLFEFIAI
KTAKFAKGSPMKVLIMFSFVTALVSSVLDNVTTVLLLTPMLLYITRLMDVNPIPFLLAEIFASNIGGTATLIGDPPNIMI
GSAAGLSFTEFLLNMGPIAAIDLAIALGIIYLAYRNEMKTSKAKRERILSTIERLREDEAIRDYTLFKKSVTVIIGVVLL
FFVHDRLEIPPAVVALTGASVLLMWSRMEPTEILEKIEWTAIFFFMGLFIIVGSLVETGVIDDVAQWLLGYVHTTGQALV
MVTWFSAIASAIVDNIPLTAAMIPLIKSMGTSMDVYPLWWALSLGACLGGNGTAIGASANIVVLGIASREGVKITFMDFL
KIGLVIMFTTVAAGMGLLWIRYIGV

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=504, Percent_Identity=32.7380952380952, Blast_Score=218, Evalue=1e-56,
Organism=Escherichia coli, GI1787039, Length=377, Percent_Identity=23.6074270557029, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082277, Length=428, Percent_Identity=21.7289719626168, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574683, Length=503, Percent_Identity=33.3996023856859, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI28574681, Length=503, Percent_Identity=33.3996023856859, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI28574685, Length=503, Percent_Identity=33.3996023856859, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI28574678, Length=503, Percent_Identity=33.3996023856859, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI19920704, Length=503, Percent_Identity=33.3996023856859, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24581759, Length=503, Percent_Identity=33.3996023856859, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI221472711, Length=477, Percent_Identity=29.3501048218029, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24581764, Length=476, Percent_Identity=28.5714285714286, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45550608, Length=464, Percent_Identity=31.6810344827586, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI85724998, Length=479, Percent_Identity=26.0960334029228, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI62484377, Length=479, Percent_Identity=26.0960334029228, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24656008, Length=466, Percent_Identity=27.0386266094421, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 46215; Mature: 46215

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQVIIAVAVFLFTYALIISERVHRTVAALFGASIVLFLGIVPWEMLPEYLDLGTLLLLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GMMIIVNTAKASGLFEFIAIKTAKFAKGSPMKVLIMFSFVTALVSSVLDNVTTVLLLTPM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYITRLMDVNPIPFLLAEIFASNIGGTATLIGDPPNIMIGSAAGLSFTEFLLNMGPIAA
HHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCHHHHHHHCCCCHHH
IDLAIALGIIYLAYRNEMKTSKAKRERILSTIERLREDEAIRDYTLFKKSVTVIIGVVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVHDRLEIPPAVVALTGASVLLMWSRMEPTEILEKIEWTAIFFFMGLFIIVGSLVETGV
HHHHHHCCCCHHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
IDDVAQWLLGYVHTTGQALVMVTWFSAIASAIVDNIPLTAAMIPLIKSMGTSMDVYPLWW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
ALSLGACLGGNGTAIGASANIVVLGIASREGVKITFMDFLKIGLVIMFTTVAAGMGLLWI
HHHHHHHCCCCCCEECCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
RYIGV
HHHCC
>Mature Secondary Structure
MEQVIIAVAVFLFTYALIISERVHRTVAALFGASIVLFLGIVPWEMLPEYLDLGTLLLLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GMMIIVNTAKASGLFEFIAIKTAKFAKGSPMKVLIMFSFVTALVSSVLDNVTTVLLLTPM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLYITRLMDVNPIPFLLAEIFASNIGGTATLIGDPPNIMIGSAAGLSFTEFLLNMGPIAA
HHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCHHHHHHHCCCCHHH
IDLAIALGIIYLAYRNEMKTSKAKRERILSTIERLREDEAIRDYTLFKKSVTVIIGVVLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVHDRLEIPPAVVALTGASVLLMWSRMEPTEILEKIEWTAIFFFMGLFIIVGSLVETGV
HHHHHHCCCCHHHHHHCCCHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
IDDVAQWLLGYVHTTGQALVMVTWFSAIASAIVDNIPLTAAMIPLIKSMGTSMDVYPLWW
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
ALSLGACLGGNGTAIGASANIVVLGIASREGVKITFMDFLKIGLVIMFTTVAAGMGLLWI
HHHHHHHCCCCCCEECCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
RYIGV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]