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The map label for this gene is tldD [C]

Identifier: 212224605

GI number: 212224605

Start: 1331505

End: 1332866

Strand: Reverse

Name: tldD [C]

Synonym: TON_1454

Alternate gene names: 212224605

Gene position: 1332866-1331505 (Counterclockwise)

Preceding gene: 212224608

Following gene: 212224604

Centisome position: 72.14

GC content: 55.14

Gene sequence:

>1362_bases
ATGGAGAGATTGATGAGAAAAGCTGAGGAGCTGGCGAGACGTTACGGTATATCATATTATGAAATACGGATAACCAAGGT
CACCGCTTCACACCTCACCATGCAGAACTCTCAGCTTGAGGAGCTTGCTCTTAACACCGAAATCGGTATAGGCGTAAGGG
CCTTCAATGGGGCCTGGGGCTTCTCAAGCGCCAATGACATGAGCAGGGCGGAGAGGGCGATAGAAACGGCCATGAAGATA
GCGAAGCTCTCGAAGGGTGACTCGAGGATATACCTTGGCGATCCCGTGAAGGACAGGGCGGAGATAAAGGTCAAGCAATC
TTTTTTGGACGTCGACATCGAGGACAAGCTTTCTCTTGTCAAGGAGGTTGATTCACTCCTTAAAGGGGATTCCATTTCAA
ACAGGAGCGTTTCCTATGGGGACGGTCTAAAGGAACAGCTCTACTTCAACTCCCTCGGGAGCGAGATAGAGACGGTAGTT
CCGAGGATAAGGCTGAGCTTTTCGGTCACGGCCAAAGGCAACGGTGAGATGCAGCAGTACTGGAGGAGCTTCGGGGGAGC
AGCCGGCTGGGAGTTGGTTGAAGGGGTTGATCTGACTCACTGGACAGCCTTTGTGAGGAGGAAGGCCATCTCCCTGCTCA
GCGCGAAGTCCCCTCCCTCCGGGGAGTTTGACGTGATAATGGATCCTGAGCTTACAGGCGTCTTCATCCACGAGGCTCTG
GGTCATGCGGCCGAGGCAGATGCTATAAAGACGGGCGAGAGCATCCTGACGGGGAGGCTCGGTGAGAGAATAGCCGTGGA
GGAGCTTACCGTCGTTGACGACCCAACTCTGCCCGGCAAGTTCGGCTCCTATATCTACGACGACGAGGGGATCAGGGCGA
AGCGCGTGGAGATAATCAAGAACGGCGTTCTCCTCAACTACCTCAACGACAGAGAGACAGCGGCAGTTTTGGGCTTGGAG
CCTAACGGTCACGGCAGGGCTCAGGGCTACAGCTACCAGCCCCTCGTGAGGATGTCCAACACCTACGTTGAACCCCGGGA
CTGGAGCTTTGAGGAGATGCTGAGCGAGGTTAAGCGTGGCCTCTACATGATAGGCGACAAGGGCGGTGAGGTTGATACCG
CCAACGGGACGTTCACCTTTGGAGCTAAAGAGGGCTACATAATCGAGAACGGCGAGATAAAGGAGCAGGTTCGTGACGTC
GCTCTATCCGGCAAGATACTTGACGTCCTGAAGAATATACGTGCCATAGGGAGCGACCTGGTCGTTGAGTTCCCCGGCTA
CTGCGGCAAGGGCCAGTGGGTTCCGGTTGACGATGGTGGGCCGCACGTTCTAACGAGGGCTGTTGTTGGGGGATTAAGAT
GA

Upstream 100 bases:

>100_bases
TTCATTACGCCTCTCCATGTCCAACACTTAAACTCTTGTGGTTCACCTCTCTATAGGAACGAATATAAATGCTCTCCCTT
TTATGTCCTCTGGTGAGGGT

Downstream 100 bases:

>100_bases
TCGAGAGACTCATCAGAATCCTGGAGCGGGAAAACGTTGAGTGGGAGATTTACTGGGAGAGAGGTCGTGGCGGTTCCTTT
AAGATAGAGAACGAGAAGCT

Product: zinc-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MERLMRKAEELARRYGISYYEIRITKVTASHLTMQNSQLEELALNTEIGIGVRAFNGAWGFSSANDMSRAERAIETAMKI
AKLSKGDSRIYLGDPVKDRAEIKVKQSFLDVDIEDKLSLVKEVDSLLKGDSISNRSVSYGDGLKEQLYFNSLGSEIETVV
PRIRLSFSVTAKGNGEMQQYWRSFGGAAGWELVEGVDLTHWTAFVRRKAISLLSAKSPPSGEFDVIMDPELTGVFIHEAL
GHAAEADAIKTGESILTGRLGERIAVEELTVVDDPTLPGKFGSYIYDDEGIRAKRVEIIKNGVLLNYLNDRETAAVLGLE
PNGHGRAQGYSYQPLVRMSNTYVEPRDWSFEEMLSEVKRGLYMIGDKGGEVDTANGTFTFGAKEGYIIENGEIKEQVRDV
ALSGKILDVLKNIRAIGSDLVVEFPGYCGKGQWVPVDDGGPHVLTRAVVGGLR

Sequences:

>Translated_453_residues
MERLMRKAEELARRYGISYYEIRITKVTASHLTMQNSQLEELALNTEIGIGVRAFNGAWGFSSANDMSRAERAIETAMKI
AKLSKGDSRIYLGDPVKDRAEIKVKQSFLDVDIEDKLSLVKEVDSLLKGDSISNRSVSYGDGLKEQLYFNSLGSEIETVV
PRIRLSFSVTAKGNGEMQQYWRSFGGAAGWELVEGVDLTHWTAFVRRKAISLLSAKSPPSGEFDVIMDPELTGVFIHEAL
GHAAEADAIKTGESILTGRLGERIAVEELTVVDDPTLPGKFGSYIYDDEGIRAKRVEIIKNGVLLNYLNDRETAAVLGLE
PNGHGRAQGYSYQPLVRMSNTYVEPRDWSFEEMLSEVKRGLYMIGDKGGEVDTANGTFTFGAKEGYIIENGEIKEQVRDV
ALSGKILDVLKNIRAIGSDLVVEFPGYCGKGQWVPVDDGGPHVLTRAVVGGLR
>Mature_453_residues
MERLMRKAEELARRYGISYYEIRITKVTASHLTMQNSQLEELALNTEIGIGVRAFNGAWGFSSANDMSRAERAIETAMKI
AKLSKGDSRIYLGDPVKDRAEIKVKQSFLDVDIEDKLSLVKEVDSLLKGDSISNRSVSYGDGLKEQLYFNSLGSEIETVV
PRIRLSFSVTAKGNGEMQQYWRSFGGAAGWELVEGVDLTHWTAFVRRKAISLLSAKSPPSGEFDVIMDPELTGVFIHEAL
GHAAEADAIKTGESILTGRLGERIAVEELTVVDDPTLPGKFGSYIYDDEGIRAKRVEIIKNGVLLNYLNDRETAAVLGLE
PNGHGRAQGYSYQPLVRMSNTYVEPRDWSFEEMLSEVKRGLYMIGDKGGEVDTANGTFTFGAKEGYIIENGEIKEQVRDV
ALSGKILDVLKNIRAIGSDLVVEFPGYCGKGQWVPVDDGGPHVLTRAVVGGLR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=420, Percent_Identity=31.4285714285714, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790682, Length=424, Percent_Identity=25.9433962264151, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49930; Mature: 49930

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLMRKAEELARRYGISYYEIRITKVTASHLTMQNSQLEELALNTEIGIGVRAFNGAWG
CHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHEECCCHHHHHHHCCCCCCEEEEECCCCC
FSSANDMSRAERAIETAMKIAKLSKGDSRIYLGDPVKDRAEIKVKQSFLDVDIEDKLSLV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHEEEEHHHHCCCHHHHHHHH
KEVDSLLKGDSISNRSVSYGDGLKEQLYFNSLGSEIETVVPRIRLSFSVTAKGNGEMQQY
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHH
WRSFGGAAGWELVEGVDLTHWTAFVRRKAISLLSAKSPPSGEFDVIMDPELTGVFIHEAL
HHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHH
GHAAEADAIKTGESILTGRLGERIAVEELTVVDDPTLPGKFGSYIYDDEGIRAKRVEIIK
CCHHCCHHHHCCHHHHHHCCCCEEEHEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHH
NGVLLNYLNDRETAAVLGLEPNGHGRAQGYSYQPLVRMSNTYVEPRDWSFEEMLSEVKRG
CCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCC
LYMIGDKGGEVDTANGTFTFGAKEGYIIENGEIKEQVRDVALSGKILDVLKNIRAIGSDL
EEEEECCCCCEECCCCEEEECCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCE
VVEFPGYCGKGQWVPVDDGGPHVLTRAVVGGLR
EEECCCCCCCCCEEECCCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MERLMRKAEELARRYGISYYEIRITKVTASHLTMQNSQLEELALNTEIGIGVRAFNGAWG
CHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHEECCCHHHHHHHCCCCCCEEEEECCCCC
FSSANDMSRAERAIETAMKIAKLSKGDSRIYLGDPVKDRAEIKVKQSFLDVDIEDKLSLV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHEEEEHHHHCCCHHHHHHHH
KEVDSLLKGDSISNRSVSYGDGLKEQLYFNSLGSEIETVVPRIRLSFSVTAKGNGEMQQY
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHH
WRSFGGAAGWELVEGVDLTHWTAFVRRKAISLLSAKSPPSGEFDVIMDPELTGVFIHEAL
HHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHH
GHAAEADAIKTGESILTGRLGERIAVEELTVVDDPTLPGKFGSYIYDDEGIRAKRVEIIK
CCHHCCHHHHCCHHHHHHCCCCEEEHEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHH
NGVLLNYLNDRETAAVLGLEPNGHGRAQGYSYQPLVRMSNTYVEPRDWSFEEMLSEVKRG
CCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHCC
LYMIGDKGGEVDTANGTFTFGAKEGYIIENGEIKEQVRDVALSGKILDVLKNIRAIGSDL
EEEEECCCCCEECCCCEEEECCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHHHCCCCE
VVEFPGYCGKGQWVPVDDGGPHVLTRAVVGGLR
EEECCCCCCCCCEEECCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]