BacMap

Definition	Thermococcus onnurineus NA1, complete genome.
Accession	NC_011529
Length	1,847,607

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The map label for this gene is sufC [H]

Identifier: 212224000

GI number: 212224000

Start: 788343

End: 789086

Strand: Reverse

Name: sufC [H]

Synonym: TON_0851

Alternate gene names: 212224000

Gene position: 789086-788343 (Counterclockwise)

Preceding gene: 212224001

Following gene: 212223999

Centisome position: 42.71

GC content: 52.42

Gene sequence:

>744_bases
ATGCTAAAGGTGGAAAATCTCCATGTTAAGGTTGCGGACAAGGGAATACTCCGGGGAGTAAGCTTTGAACTGGGTGGAGG
AGAGCTTCACGTGGTCATGGGACCCAACGGAAGCGGAAAATCTACTTTAGCCCTCACGATTGCCGGACATCCGAAGTACG
AGGTTGTCAAGGGAAGGATACTCTTCGAAGGAGCGGACATAACCCACACAAAGCCGGAAGATAGGGCTAAGAAGGGCATA
TTCCTCAGCTTCCAGCACCCCGTTGAAGTCGAGGGGGTTAAGGTCATACAGTTCTTCCAGAGGATGCTCAAGAACCTCAG
GGGCATTGACGAGGTTGAGGCCTACGACATGATATTTAGGGCCGTTGAGGAGCTTGGCTTCGACAGCTCGATGCTCTCAA
GGGAGCTCAACGTCGGCTTCTCCGGCGGTGAGAGGAAGAAGCTTGAGATGCTCCAGGCGTACCTTGTGAAGCCGAAGCTT
CTTATCCTCGACGAACCCGACAGCGGTGTTGACGTCGATTCTCTCAAAGTCATAGCGGGAATAATAGCCAAACTCCACCG
CGAGGGGACGAGCATACTCCTAATCACGCACTACGGCAGGATACTAGAGTACCTCAATCCCCAGAGAGTTCACATCATCA
AGGATGGGCGGCTTGTCGTTTCTGGCGGAATGGAGCTTGTAAAACTCATTGAAGAGAAAGGCTTCGCGGCGGTGAAAGAC
AATGACAGGGCAGACAAGGCTTGA

Upstream 100 bases:

>100_bases
CTACCTTTTCTGGATTTCTTAAGTATACAAATTTGTGAAGAAAGGTTTTAAAAGTGTGCGTTTCTACACAAACTCGGGTA
AAGAAAGGACGGTGATGGTT

Downstream 100 bases:

>100_bases
GGAGATCCTCAAGGCCGGCTCGCTGGAGGAAATCCTTGGTACGGCAGTGCCATATCCTAAGGAAATCGAGCTGAAAGGCG
AGCTGACCAGGGACATGATA

Product: ATP-dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MLKVENLHVKVADKGILRGVSFELGGGELHVVMGPNGSGKSTLALTIAGHPKYEVVKGRILFEGADITHTKPEDRAKKGI
FLSFQHPVEVEGVKVIQFFQRMLKNLRGIDEVEAYDMIFRAVEELGFDSSMLSRELNVGFSGGERKKLEMLQAYLVKPKL
LILDEPDSGVDVDSLKVIAGIIAKLHREGTSILLITHYGRILEYLNPQRVHIIKDGRLVVSGGMELVKLIEEKGFAAVKD
NDRADKA

Sequences:

>Translated_247_residues
MLKVENLHVKVADKGILRGVSFELGGGELHVVMGPNGSGKSTLALTIAGHPKYEVVKGRILFEGADITHTKPEDRAKKGI
FLSFQHPVEVEGVKVIQFFQRMLKNLRGIDEVEAYDMIFRAVEELGFDSSMLSRELNVGFSGGERKKLEMLQAYLVKPKL
LILDEPDSGVDVDSLKVIAGIIAKLHREGTSILLITHYGRILEYLNPQRVHIIKDGRLVVSGGMELVKLIEEKGFAAVKD
NDRADKA
>Mature_247_residues
MLKVENLHVKVADKGILRGVSFELGGGELHVVMGPNGSGKSTLALTIAGHPKYEVVKGRILFEGADITHTKPEDRAKKGI
FLSFQHPVEVEGVKVIQFFQRMLKNLRGIDEVEAYDMIFRAVEELGFDSSMLSRELNVGFSGGERKKLEMLQAYLVKPKL
LILDEPDSGVDVDSLKVIAGIIAKLHREGTSILLITHYGRILEYLNPQRVHIIKDGRLVVSGGMELVKLIEEKGFAAVKD
NDRADKA

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=239, Percent_Identity=28.4518828451883, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI116734710, Length=216, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI62526033, Length=241, Percent_Identity=24.896265560166, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI21536376, Length=233, Percent_Identity=28.755364806867, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI150417984, Length=208, Percent_Identity=28.8461538461538, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787972, Length=247, Percent_Identity=44.5344129554656, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1786319, Length=219, Percent_Identity=30.5936073059361, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786698, Length=198, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788506, Length=234, Percent_Identity=29.4871794871795, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786563, Length=201, Percent_Identity=29.3532338308458, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789672, Length=198, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787370, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789891, Length=211, Percent_Identity=27.4881516587678, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787029, Length=231, Percent_Identity=25.1082251082251, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=224, Percent_Identity=29.4642857142857, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789991, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790525, Length=218, Percent_Identity=27.0642201834862, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789864, Length=243, Percent_Identity=24.2798353909465, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790190, Length=209, Percent_Identity=29.6650717703349, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082267, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081782, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994883, Length=217, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787792, Length=234, Percent_Identity=24.7863247863248, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787759, Length=236, Percent_Identity=26.271186440678, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789962, Length=213, Percent_Identity=26.7605633802817, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790162, Length=204, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786703, Length=204, Percent_Identity=27.9411764705882, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787143, Length=228, Percent_Identity=27.6315789473684, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI87081709, Length=201, Percent_Identity=22.8855721393035, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=224, Percent_Identity=26.3392857142857, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=233, Percent_Identity=25.7510729613734, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=236, Percent_Identity=28.3898305084746, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71988343, Length=226, Percent_Identity=27.8761061946903, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=182, Percent_Identity=25.8241758241758, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=219, Percent_Identity=24.2009132420091, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=217, Percent_Identity=27.1889400921659, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324498, Length=242, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320214, Length=178, Percent_Identity=29.7752808988764, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322177, Length=197, Percent_Identity=29.4416243654822, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24666092, Length=219, Percent_Identity=32.4200913242009, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643674, Length=224, Percent_Identity=29.0178571428571, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221512771, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647959, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI85816269, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580553, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85724864, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580555, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574744, Length=216, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666836, Length=224, Percent_Identity=25.4464285714286, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24659289, Length=227, Percent_Identity=28.6343612334802, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27327; Mature: 27327

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVENLHVKVADKGILRGVSFELGGGELHVVMGPNGSGKSTLALTIAGHPKYEVVKGRI
CCEEEEEEEEEECCCCEEEEEEEECCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEEE
LFEGADITHTKPEDRAKKGIFLSFQHPVEVEGVKVIQFFQRMLKNLRGIDEVEAYDMIFR
EEECCCCCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AVEELGFDSSMLSRELNVGFSGGERKKLEMLQAYLVKPKLLILDEPDSGVDVDSLKVIAG
HHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
IIAKLHREGTSILLITHYGRILEYLNPQRVHIIKDGRLVVSGGMELVKLIEEKGFAAVKD
HHHHHHCCCCEEEEEECHHHHHHHCCCCEEEEEECCEEEEECCHHHHHHHHHCCCEEECC
NDRADKA
CCCCCCC
>Mature Secondary Structure
MLKVENLHVKVADKGILRGVSFELGGGELHVVMGPNGSGKSTLALTIAGHPKYEVVKGRI
CCEEEEEEEEEECCCCEEEEEEEECCCEEEEEECCCCCCCEEEEEEEECCCCEEEEEEEE
LFEGADITHTKPEDRAKKGIFLSFQHPVEVEGVKVIQFFQRMLKNLRGIDEVEAYDMIFR
EEECCCCCCCCCHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AVEELGFDSSMLSRELNVGFSGGERKKLEMLQAYLVKPKLLILDEPDSGVDVDSLKVIAG
HHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
IIAKLHREGTSILLITHYGRILEYLNPQRVHIIKDGRLVVSGGMELVKLIEEKGFAAVKD
HHHHHHCCCCEEEEEECHHHHHHHCCCCEEEEEECCEEEEECCHHHHHHHHHCCCEEECC
NDRADKA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]