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The map label for this gene is mptA [H]

Identifier: 212223906

GI number: 212223906

Start: 706509

End: 707315

Strand: Reverse

Name: mptA [H]

Synonym: TON_0757

Alternate gene names: 212223906

Gene position: 707315-706509 (Counterclockwise)

Preceding gene: 212223907

Following gene: 212223905

Centisome position: 38.28

GC content: 53.16

Gene sequence:

>807_bases
ATGCCGATATTCGAGACCCAGGAAGAGATTCCCGAGATTAGAGAGCGCCTTCACCGTGTCGGAATAACAAATCTCCGAAC
GGTGGCAAAGATAAACTGGAAAGGAAGGGTGTACACTTTCCTCCCGCTCTTTGAGATAACTATCGACGTTCCGGAGGAGA
AGAAGGGCATACACATGAGCAGGCTCGTGGAGAGCATAACAGAGGCGATGAGCGAGGCCGTTGAGGAAGAGGTGATGGAA
GCTCACAGCTCGCTCGAAGAGCTTGGGAAGGCAGTCATTTATAGGCTCGAAGGCAAGCACCCACACAAGAGGGCTGAGGT
CTGGATAAGGACTCACCTCATAATCCCTCGCGAGACTCCGGCGAGCAAAAAGACCACCTACGAGCCCTATGACGTTGAAG
TCGGTGTCATCAAGAACGAGGACGGAAGCTTTGAGAAGATTCTGAGGGTTAAGGTTATCGGAAACACCGCCTGTCCGCAC
GCTATGGCGAACAACAACGGCAAGACGCACATACAGAGGGCGATAGGCGAGCTTGAGGTAAGAACGGCCTTTGACGAGGA
GATAGCACTTGAGGATATGATAGACGTCGTTGAGAGCTCCTTCAGCCACCCAACCTACACGCTACTCAAGACGGTAGATG
AGAACGCCGTCGTTCAGGGCATGTACAGGAACCCGAAGTTTGTCGAGGACGTTGCGCGCGAGATATTCGCCAAGGCGAAG
AAGCGCTTTAAGGGCAGGATTCACGTGAGGGTCATCAGCAACGAGAGCATCCATAAGCACGACGTCATAGCGGAGACGTG
GAGCTGA

Upstream 100 bases:

>100_bases
AAAGCTCGCGAGGAAAAGCTACGAGAGGCTGATGAGCCTGCTGAGGTAGGTTTAAAAGGGGCCCCGATTAGATAACCCTA
AAAAGTTCAGGGTGATACTC

Downstream 100 bases:

>100_bases
CTTTCTCAATTTTCGGGGTGTTCCTTGTGAAAGTCATCCGCGACGCCATTCACGGAGACATAGTCCTGGACGAGTTTGCG
CTGAGGATTGTTGACACGCC

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MPIFETQEEIPEIRERLHRVGITNLRTVAKINWKGRVYTFLPLFEITIDVPEEKKGIHMSRLVESITEAMSEAVEEEVME
AHSSLEELGKAVIYRLEGKHPHKRAEVWIRTHLIIPRETPASKKTTYEPYDVEVGVIKNEDGSFEKILRVKVIGNTACPH
AMANNNGKTHIQRAIGELEVRTAFDEEIALEDMIDVVESSFSHPTYTLLKTVDENAVVQGMYRNPKFVEDVAREIFAKAK
KRFKGRIHVRVISNESIHKHDVIAETWS

Sequences:

>Translated_268_residues
MPIFETQEEIPEIRERLHRVGITNLRTVAKINWKGRVYTFLPLFEITIDVPEEKKGIHMSRLVESITEAMSEAVEEEVME
AHSSLEELGKAVIYRLEGKHPHKRAEVWIRTHLIIPRETPASKKTTYEPYDVEVGVIKNEDGSFEKILRVKVIGNTACPH
AMANNNGKTHIQRAIGELEVRTAFDEEIALEDMIDVVESSFSHPTYTLLKTVDENAVVQGMYRNPKFVEDVAREIFAKAK
KRFKGRIHVRVISNESIHKHDVIAETWS
>Mature_267_residues
PIFETQEEIPEIRERLHRVGITNLRTVAKINWKGRVYTFLPLFEITIDVPEEKKGIHMSRLVESITEAMSEAVEEEVMEA
HSSLEELGKAVIYRLEGKHPHKRAEVWIRTHLIIPRETPASKKTTYEPYDVEVGVIKNEDGSFEKILRVKVIGNTACPHA
MANNNGKTHIQRAIGELEVRTAFDEEIALEDMIDVVESSFSHPTYTLLKTVDENAVVQGMYRNPKFVEDVAREIFAKAKK
RFKGRIHVRVISNESIHKHDVIAETWS

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: NA

Molecular weight: Translated: 30778; Mature: 30646

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIFETQEEIPEIRERLHRVGITNLRTVAKINWKGRVYTFLPLFEITIDVPEEKKGIHMS
CCCCCCHHHHHHHHHHHHHCCCCCHHEEEEEECCCEEEEEEEEEEEEEECCCCCCCCHHH
RLVESITEAMSEAVEEEVMEAHSSLEELGKAVIYRLEGKHPHKRAEVWIRTHLIIPRETP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHEEEEEEEEEECCCC
ASKKTTYEPYDVEVGVIKNEDGSFEKILRVKVIGNTACPHAMANNNGKTHIQRAIGELEV
CCCCCCCCCCEEEEEEEECCCCCHHHEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHH
RTAFDEEIALEDMIDVVESSFSHPTYTLLKTVDENAVVQGMYRNPKFVEDVAREIFAKAK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHH
KRFKGRIHVRVISNESIHKHDVIAETWS
HHCCCEEEEEEECCCCCCHHHCHHCCCC
>Mature Secondary Structure 
PIFETQEEIPEIRERLHRVGITNLRTVAKINWKGRVYTFLPLFEITIDVPEEKKGIHMS
CCCCCHHHHHHHHHHHHHCCCCCHHEEEEEECCCEEEEEEEEEEEEEECCCCCCCCHHH
RLVESITEAMSEAVEEEVMEAHSSLEELGKAVIYRLEGKHPHKRAEVWIRTHLIIPRETP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHEEEEEEEEEECCCC
ASKKTTYEPYDVEVGVIKNEDGSFEKILRVKVIGNTACPHAMANNNGKTHIQRAIGELEV
CCCCCCCCCCEEEEEEEECCCCCHHHEEEEEEECCCCCCCHHCCCCCHHHHHHHHHHHHH
RTAFDEEIALEDMIDVVESSFSHPTYTLLKTVDENAVVQGMYRNPKFVEDVAREIFAKAK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHH
KRFKGRIHVRVISNESIHKHDVIAETWS
HHCCCEEEEEEECCCCCCHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA