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The map label for this gene is ribD [H]

Identifier: 212223758

GI number: 212223758

Start: 562153

End: 563238

Strand: Reverse

Name: ribD [H]

Synonym: TON_0610

Alternate gene names: 212223758

Gene position: 563238-562153 (Counterclockwise)

Preceding gene: 212223761

Following gene: 212223757

Centisome position: 30.48

GC content: 48.99

Gene sequence:

>1086_bases
ATGATGGACGAAGACAAGAAGTTTATGCATCTCGCGCTGGAGCTGGCAAAGCGCGGAGAGGGCTGGGTAAACCCTAATCC
AATGGTTGGGGCAGTCATAGTCAAAGATGGTGAGGTAATAGGTGTTGGATGGCACAGGAAGTTTGGGGAAAAGCATGCCG
AAATTAACGCTATCGAGGACGCCAAGGATCGGGGACACGACACTAGGGGAGCAACATTGTATGTAACGCTCGAACCGTGC
TCTCACTGGGGAAAGCAGCCACCATGTGCCGATAGAATAATCGCTGAAGGCTTTAAACGAGTGGTCGTGGCAATGAAGGA
TCCTCACTCACTTGTCGCGGGCAGGGGCATTGAAAAGATGCAGAGAGCAGGCATAGAAGTTGATGTCGGCATCCTTGAGG
AAGAGGCGAAAAAGCTGAATGAGATTTTCATCAAATATATAACTACCAAGATACCATTCGTTTCAATAAAGCTCGCCCTA
ACTCTCGACGGTTTTATTGCTACAGAAAGCTTCTCTTCTCAGTGGATAACAGGAGATAAGGCGAGGCAAAAGGTTCAGGA
GCTCAGGAGAAGGCACATGGCAATCATGGTTGGAGCCGGAACGATTCTTAGGGACAACCCGAAGCTCAACTGTCGCCTTC
CTGAATGTCCCCCAAAATACAAGGTTATCCTCGACAGACACGGCCTTATCGGTGAGGAGCTGAGCGGCGGTAGACGTTTC
CGTCTCTTCAATGATGGAAACGTAATAATCTTCACAGAAAATCCGGAAGCGTTTGGAGAAGTAAACGCCACTATTGTCGA
GGAAACCGATCCTGAAAGAATTCTTAGAAAGCTCGGCGAGATGGGGATAGACAGCGTCTTGATTGAAGGTGGAAGAATAG
CCTGCCAGTTCTTGAGCTATGCCGACAAGTTCTACATCTTCTATGGGCCAAAGCTCTTTGGGAGGGGAATAAAGCCTTTC
GAGTGCCTCAGCGTGAAAGAAGCCAACGAGGCACCGGTGTTAGAGATAGAATCAATCGAGAAGCTCGGTGAGAGCCTCCT
TGTTACAGCTTACCCGGGTGATTGTGGTGTTCAGCGGCATTATTGA

Upstream 100 bases:

>100_bases
GGAAATCACCGCTTTAACGCTATGAATGAGACAATAAAAAGATTCTGTTATTCCAATTTTGGAACAAATTCTTAAAAATT
ATGGAACAATTTTCTGAAAC

Downstream 100 bases:

>100_bases
GGCCATAGGCAAGGCGAGATACTCTGCTGGAAGGCTCCATGTCGAAGTCCCTTTCAAGGTTACGCCGGGAGCTAGTGTGG
CAGTAAATGGGGCCTGCCTG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MMDEDKKFMHLALELAKRGEGWVNPNPMVGAVIVKDGEVIGVGWHRKFGEKHAEINAIEDAKDRGHDTRGATLYVTLEPC
SHWGKQPPCADRIIAEGFKRVVVAMKDPHSLVAGRGIEKMQRAGIEVDVGILEEEAKKLNEIFIKYITTKIPFVSIKLAL
TLDGFIATESFSSQWITGDKARQKVQELRRRHMAIMVGAGTILRDNPKLNCRLPECPPKYKVILDRHGLIGEELSGGRRF
RLFNDGNVIIFTENPEAFGEVNATIVEETDPERILRKLGEMGIDSVLIEGGRIACQFLSYADKFYIFYGPKLFGRGIKPF
ECLSVKEANEAPVLEIESIEKLGESLLVTAYPGDCGVQRHY

Sequences:

>Translated_361_residues
MMDEDKKFMHLALELAKRGEGWVNPNPMVGAVIVKDGEVIGVGWHRKFGEKHAEINAIEDAKDRGHDTRGATLYVTLEPC
SHWGKQPPCADRIIAEGFKRVVVAMKDPHSLVAGRGIEKMQRAGIEVDVGILEEEAKKLNEIFIKYITTKIPFVSIKLAL
TLDGFIATESFSSQWITGDKARQKVQELRRRHMAIMVGAGTILRDNPKLNCRLPECPPKYKVILDRHGLIGEELSGGRRF
RLFNDGNVIIFTENPEAFGEVNATIVEETDPERILRKLGEMGIDSVLIEGGRIACQFLSYADKFYIFYGPKLFGRGIKPF
ECLSVKEANEAPVLEIESIEKLGESLLVTAYPGDCGVQRHY
>Mature_361_residues
MMDEDKKFMHLALELAKRGEGWVNPNPMVGAVIVKDGEVIGVGWHRKFGEKHAEINAIEDAKDRGHDTRGATLYVTLEPC
SHWGKQPPCADRIIAEGFKRVVVAMKDPHSLVAGRGIEKMQRAGIEVDVGILEEEAKKLNEIFIKYITTKIPFVSIKLAL
TLDGFIATESFSSQWITGDKARQKVQELRRRHMAIMVGAGTILRDNPKLNCRLPECPPKYKVILDRHGLIGEELSGGRRF
RLFNDGNVIIFTENPEAFGEVNATIVEETDPERILRKLGEMGIDSVLIEGGRIACQFLSYADKFYIFYGPKLFGRGIKPF
ECLSVKEANEAPVLEIESIEKLGESLLVTAYPGDCGVQRHY

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=359, Percent_Identity=36.2116991643454, Blast_Score=224, Evalue=6e-60,
Organism=Escherichia coli, GI145693172, Length=148, Percent_Identity=35.8108108108108, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40408; Mature: 40408

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDEDKKFMHLALELAKRGEGWVNPNPMVGAVIVKDGEVIGVGWHRKFGEKHAEINAIED
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEECCHHHHCCCCCCCCCCHH
AKDRGHDTRGATLYVTLEPCSHWGKQPPCADRIIAEGFKRVVVAMKDPHSLVAGRGIEKM
HHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHEEEEEECCCHHHHHCCCHHHH
QRAGIEVDVGILEEEAKKLNEIFIKYITTKIPFVSIKLALTLDGFIATESFSSQWITGDK
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCCCCCCHH
ARQKVQELRRRHMAIMVGAGTILRDNPKLNCRLPECPPKYKVILDRHGLIGEELSGGRRF
HHHHHHHHHHHCEEEEEECCEEEECCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCEEE
RLFNDGNVIIFTENPEAFGEVNATIVEETDPERILRKLGEMGIDSVLIEGGRIACQFLSY
EEEECCCEEEEECCCHHHCCCCEEEEECCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHH
ADKFYIFYGPKLFGRGIKPFECLSVKEANEAPVLEIESIEKLGESLLVTAYPGDCGVQRH
CCEEEEEECCHHHCCCCCCEEEEECCCCCCCCEEEHHHHHHCCCEEEEEECCCCCCCCCC
Y
C
>Mature Secondary Structure
MMDEDKKFMHLALELAKRGEGWVNPNPMVGAVIVKDGEVIGVGWHRKFGEKHAEINAIED
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEECCHHHHCCCCCCCCCCHH
AKDRGHDTRGATLYVTLEPCSHWGKQPPCADRIIAEGFKRVVVAMKDPHSLVAGRGIEKM
HHHCCCCCCCEEEEEEECCHHHCCCCCCHHHHHHHHHHHEEEEEECCCHHHHHCCCHHHH
QRAGIEVDVGILEEEAKKLNEIFIKYITTKIPFVSIKLALTLDGFIATESFSSQWITGDK
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCCCCCCHH
ARQKVQELRRRHMAIMVGAGTILRDNPKLNCRLPECPPKYKVILDRHGLIGEELSGGRRF
HHHHHHHHHHHCEEEEEECCEEEECCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCEEE
RLFNDGNVIIFTENPEAFGEVNATIVEETDPERILRKLGEMGIDSVLIEGGRIACQFLSY
EEEECCCEEEEECCCHHHCCCCEEEEECCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHH
ADKFYIFYGPKLFGRGIKPFECLSVKEANEAPVLEIESIEKLGESLLVTAYPGDCGVQRH
CCEEEEEECCHHHCCCCCCEEEEECCCCCCCCEEEHHHHHHCCCEEEEEECCCCCCCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]