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The map label for this gene is pls [H]

Identifier: 212223454

GI number: 212223454

Start: 273678

End: 277922

Strand: Reverse

Name: pls [H]

Synonym: TON_0308

Alternate gene names: 212223454

Gene position: 277922-273678 (Counterclockwise)

Preceding gene: 212223455

Following gene: 212223453

Centisome position: 15.04

GC content: 52.46

Gene sequence:

>4245_bases
ATGAACAAAAAGGCTCTGAGCCTTTTAGTCGTGGTAGTGATGCTACTCTCTGCGATCCCAGCGGCAGTATCAGTGCTAGC
AGTAACGGCGACTCCAGTACAGCAGTCCGAGAGCCCCCAGCAGATCGAGGTGGAGAAGCCCAGCAATTTCATACCAGGGG
AAGTCCTTCAGAAGGAAATCCAGAAGGTTCTGGAGAGCAGCGGTAAGACGGTGCGCCTCATAGTGGCACCGGATAGGGAT
CACAGGACTGAGGTTTACAACGCCCTTAAGAGCCTTGGTAAGATTGACCCCATCAGCAAACCTGAGCTGCAGTTCATAGT
TGTTGAAATGCCGGTTTCCAACGTTGAAAAGCTCGCTGAAATACCCGGAATACTCCACGTCTGGAAGGACGAGATGGTCA
AGCTCGAGGAGCCCGTTGCCCCTGAGGCCGGGGCAGGAGATGTTTCTCCAGATGCCAGCTTCCCCACTCACCCGGACATG
TTCATGAGCATCTTCACGATTCACGCTTACGACACATGGGTTAATTATGGCGTCCTCGGAGACAATGTCACCGTTGCCGT
TCTTGACACTGGAATTGACGTCGGCCACCCGTTCCTCCAGGTCACCCTCGATGGAAGGCCTAAGATTGTGAACATATACG
ACGCCAGTGATGAGGGGCTCGCGGAGATATACTACTCCACCAACACCACGTCTAGTGGCTACATAACAGTCGATAAGAAC
GTCACCCTGTTCTGGGGTGTTTATGCGCCGTACTACGGCCACGATGCATATTACACGAACTACACCATGGGAACCTATTA
CATCGGCAACATAACCGGTGACATGTACTATATAGGACTCCTCCCGGAGAGGTACTTTGACTTGAACTTTGATGGTGATA
AGAACGATGTTTACCCGATTCTCGTCGTTGACAACAATGGCACTTACACCGCATACATGGATATCAATATGAACAATAAC
TTTACTGATGATACTGGGGTTGGCCTCTATACTGAGACAGGTGAGTACTTCACCTTCAACACCAGCCTCGTTAACGTTGC
GTTTGCCGAGTTCATGGCTCCATACTACGCAATGTTCATGTGGGACGCTCACGGTCACGGAACTCACGTCAGCGGTACCG
TTGCCGGCGTTGGCCTTCCAGACGACCCGCTTTTCGGCGGTGTGTATGGAGTTGCCCCCAACGCCCAGCTCATGGAGGTC
AAGGTTCTTCCGGGTGAGTTTGGATTTGGAAGGACTAGCTGGATCATCGGCGGAATGATATACGCCACCCTCAACGGTGC
GGACGTCATAAGCATGTCCCTAGGTGGTGGAGGCGAGATAAACGACGGTATAGAGAGCCCGGAGAACTTCTACGTTAACC
TGCTAACCGACTGGTACGGTGTTACATTTGCCATAGCCGCAGGAAACGAGGGCCCGACCACCAACACCGTCCACTCACCG
GGTGACAGCGACCTCGCCATAACCGTCGGCAACTACGTAGACAACGAGAGGGAGTCCTTCTGGTACGGGGTTGATATGGG
CATAATCTCCGGTCCAGCTATGAGCTCCAGCAGGGGACCGAGGGACGACGGTATGCTCGACCCCGACGTCATGGCTCCGG
GTACCGACATATTCTCGAGCCTGCCGATGTGGTACACTATCGTTTACAACGACTCCAACAGATACTATGGAATATGGAGC
GGTACCTCAATGGCCACTCCGCATGTCAGCGGTGCCGTTGCCCTGATGATTAGCTACGCCAAGCAGCACAACCTGACCTA
TGATCCCATAATGATAAAGCGCGCCCTCGAACTCAGCGCCAAGCCCGTCAATGGGACCCTTATAGATCAGGGCTTCGGCC
TCATACAGGTGGACAAGGCCATCGAGGAGCTTGAGAAGCTCAGCCAGGAGCCGACCACCTACATCTTCGCCGGAACCACC
TACACCGGCTTCAAGAACCCGATAGGCGTTCCGATGATCCCGATATCACAGGCCTATGTGGACTTCAACGGCTACTTCCA
GAACGCCTTTGGCTTCCCGTACCTTTACAGGGGAGTCTACATAAGGAACGAGTATCCGGGAAGCGTTCCGATATACTTCT
CACCGCTCGTCTATGAGCCAGGTTGGGGACTCTGGTACGTCTTCCAGAACAAGACCTACAGGATAAGCACCAACGTTAAT
TGGATCATTCCCAACACCACAGAGGTCACGATCGACGGCGCCGGTGCTCAGAGCATAGACGACCTCATAGGACAGTTCTT
AATTAACATCGACTACTCCAAGCTCCAGAAGAGCGGCACCTACGTTGGACTCGTTTACATCGACGACCCCGACACCAGCT
ACATCGACGGCTACATAGCTGTCACCGTCGACATTCCGGTGAACCCGAACGGTGAAAGCTATGCCAAGCTCTCCGACACC
GAGAAGCCTGGAGAAGCCAAGCACTACTTCGTTAAGGTTCCGCGCGGCACCAAGGAGCTCCGCGTCACCCTCCGCATCGC
AACCGACGCCGAGGGCAACCCGATTGGCAGAACGACCCTTCTCATCGCCAGGCCACTCGGTGAGGTCGTTGCAGCGTACG
TTCCGGGCTACTACTACGTCGGAGCCAACCCTGCCGGAAACGTCTACGAGTACACCTGGGTTATCCCTGACCCGGTCGAG
GGAACCTGGGAGATAACCGCCTACTCGAGCGTATTCACCAAGTACTTCAGCGGCTACGACACTTCCCAGTACGAGATTGA
GGTTAATATATCATCAGTTACAATTACTCCTGAACTTATTTCTGGATATCTCACGACCCCCACAAACATTAGCGTTAGTG
CCATAGTTGAGAACAACTATGATAACTTCAACGCCACCGCCGTCGGCTACGGTCTTGGTAGGCTTGACACCAATGACGTT
ATGGTCAGAAACGTTGGCCAGGATGAGTGGGACCTCATTGGAGCCTTCTACGCTGATCCAACTACCTACTTCATCAGGTT
CGGAATAACCCAGCCCAAAGACCCCACCGCTGACCTCGACTTGTACGTGTTCTACTTCCCGACCTATGAGGATCTCCTTA
ACTTTACCAACTACACTATCTATGACTACCAGATAGGCCCAACTAGCGATGAAGTTTTTGAACAGTTCATGCCGGCGCCA
GGGTACTATGTGGTGAATGTCCATGGCTATGATACTGTGGGATACGACCAGTTGCAATACGTCTTCTACTACCAGATACT
TGGAGATAATGGGGATATCTCCACAGGAGAAAGCCCATTCCTGTTCGAAATGGGTACTAACAGGACTATAAATGCAACAA
TAGAGTTCAGCGCTAACGGCACGTATCTAGGTATCCTTGGCCTCATTAATGCAGATACTGGTGAGGGAATAACATATGCT
CCAACGATGTTCCAAGTAGGCCAGCCTGAAATGGTGATAGTTGCCTATCCCGAGGCGACCCTTGGTAAACCTTCAGTGCT
TAAGATTAGGCTCCTGGACCTTGCTACTATGGACCCCATAGCGGTTCCAGTTGCTGTTAGTATAAATGGCCAAGAGTACT
ATACCAGTACAGGAGTACTTGACATTAGCTATGTCCCATTGCACCGTACAGAGACTTTCAGGATACAGGTGATAAGCGAC
TATTACAAGGACACCTACACGGAGATCACTGTTAGGGCCAAGGAGCCAGTCGAAAATGAGGTGTACTCGCCGACCATCCT
CGAGCCATACGTGGCGGTTGGAGTCGGTGAGGTCACTGGAGTCACCACCGACGAGACCATGCTCACGATAACCGCTAACG
GGCCGAGCGGTGCCGAAGACTACATTTTCGTCACTTTGCCTGTGGATACAAGCTACATTAAGATAACCGGCGACCACATC
ATTGACTACTATACCATCGAGGGTAAGAACGCGCTCTATGCTGTCATCAAGGTAAAGTATGCCTCACCGGTCACCGTCAC
CATCGAGTACAAGACCGCCCGCTACATCGTCAGCACCTGGAACTATGTCTGGTACATGCTCTACTGGAGGTACAACCAGA
AATTTGATCCGCTCTACCAGAAGGCCGTCGAACTCGGTGTTGACAACAAGACCCTTCAGGAGGCCATGCGCTACAAGGAG
CTCGCCGACGAGTACTACGCAGAGGCAAAGAAGTACATGAACCCGTACAGAGAGAACCTCGCCGTTGCGGCACTTCCGTA
CGTCAGGAAGGCCTATCTCAACATCCTCAAGGCCTACACACTGCTCGAGGAGGCAGTTAACGAGATTGAAGGTTCCGAGG
GCTGA

Upstream 100 bases:

>100_bases
CCGGGATAGTAGAGGGGATATGGTTACTCCATAGAACGAAATATTTATATCCATGCGATTTTCACTGTATAGGTGAGCAT
TACGATTAGGAGGTGTTAGG

Downstream 100 bases:

>100_bases
TGCCCTCTTTTCTTCTCTCTTGATTTTTCTACCCAATGCTTTTAAACCACCAGATGTTTCTCTTCTCGGTGGCGCTCATG
ATATACATCAAGGTCTATCG

Product: stetterlysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1414; Mature: 1414

Protein sequence:

>1414_residues
MNKKALSLLVVVVMLLSAIPAAVSVLAVTATPVQQSESPQQIEVEKPSNFIPGEVLQKEIQKVLESSGKTVRLIVAPDRD
HRTEVYNALKSLGKIDPISKPELQFIVVEMPVSNVEKLAEIPGILHVWKDEMVKLEEPVAPEAGAGDVSPDASFPTHPDM
FMSIFTIHAYDTWVNYGVLGDNVTVAVLDTGIDVGHPFLQVTLDGRPKIVNIYDASDEGLAEIYYSTNTTSSGYITVDKN
VTLFWGVYAPYYGHDAYYTNYTMGTYYIGNITGDMYYIGLLPERYFDLNFDGDKNDVYPILVVDNNGTYTAYMDINMNNN
FTDDTGVGLYTETGEYFTFNTSLVNVAFAEFMAPYYAMFMWDAHGHGTHVSGTVAGVGLPDDPLFGGVYGVAPNAQLMEV
KVLPGEFGFGRTSWIIGGMIYATLNGADVISMSLGGGGEINDGIESPENFYVNLLTDWYGVTFAIAAGNEGPTTNTVHSP
GDSDLAITVGNYVDNERESFWYGVDMGIISGPAMSSSRGPRDDGMLDPDVMAPGTDIFSSLPMWYTIVYNDSNRYYGIWS
GTSMATPHVSGAVALMISYAKQHNLTYDPIMIKRALELSAKPVNGTLIDQGFGLIQVDKAIEELEKLSQEPTTYIFAGTT
YTGFKNPIGVPMIPISQAYVDFNGYFQNAFGFPYLYRGVYIRNEYPGSVPIYFSPLVYEPGWGLWYVFQNKTYRISTNVN
WIIPNTTEVTIDGAGAQSIDDLIGQFLINIDYSKLQKSGTYVGLVYIDDPDTSYIDGYIAVTVDIPVNPNGESYAKLSDT
EKPGEAKHYFVKVPRGTKELRVTLRIATDAEGNPIGRTTLLIARPLGEVVAAYVPGYYYVGANPAGNVYEYTWVIPDPVE
GTWEITAYSSVFTKYFSGYDTSQYEIEVNISSVTITPELISGYLTTPTNISVSAIVENNYDNFNATAVGYGLGRLDTNDV
MVRNVGQDEWDLIGAFYADPTTYFIRFGITQPKDPTADLDLYVFYFPTYEDLLNFTNYTIYDYQIGPTSDEVFEQFMPAP
GYYVVNVHGYDTVGYDQLQYVFYYQILGDNGDISTGESPFLFEMGTNRTINATIEFSANGTYLGILGLINADTGEGITYA
PTMFQVGQPEMVIVAYPEATLGKPSVLKIRLLDLATMDPIAVPVAVSINGQEYYTSTGVLDISYVPLHRTETFRIQVISD
YYKDTYTEITVRAKEPVENEVYSPTILEPYVAVGVGEVTGVTTDETMLTITANGPSGAEDYIFVTLPVDTSYIKITGDHI
IDYYTIEGKNALYAVIKVKYASPVTVTIEYKTARYIVSTWNYVWYMLYWRYNQKFDPLYQKAVELGVDNKTLQEAMRYKE
LADEYYAEAKKYMNPYRENLAVAALPYVRKAYLNILKAYTLLEEAVNEIEGSEG

Sequences:

>Translated_1414_residues
MNKKALSLLVVVVMLLSAIPAAVSVLAVTATPVQQSESPQQIEVEKPSNFIPGEVLQKEIQKVLESSGKTVRLIVAPDRD
HRTEVYNALKSLGKIDPISKPELQFIVVEMPVSNVEKLAEIPGILHVWKDEMVKLEEPVAPEAGAGDVSPDASFPTHPDM
FMSIFTIHAYDTWVNYGVLGDNVTVAVLDTGIDVGHPFLQVTLDGRPKIVNIYDASDEGLAEIYYSTNTTSSGYITVDKN
VTLFWGVYAPYYGHDAYYTNYTMGTYYIGNITGDMYYIGLLPERYFDLNFDGDKNDVYPILVVDNNGTYTAYMDINMNNN
FTDDTGVGLYTETGEYFTFNTSLVNVAFAEFMAPYYAMFMWDAHGHGTHVSGTVAGVGLPDDPLFGGVYGVAPNAQLMEV
KVLPGEFGFGRTSWIIGGMIYATLNGADVISMSLGGGGEINDGIESPENFYVNLLTDWYGVTFAIAAGNEGPTTNTVHSP
GDSDLAITVGNYVDNERESFWYGVDMGIISGPAMSSSRGPRDDGMLDPDVMAPGTDIFSSLPMWYTIVYNDSNRYYGIWS
GTSMATPHVSGAVALMISYAKQHNLTYDPIMIKRALELSAKPVNGTLIDQGFGLIQVDKAIEELEKLSQEPTTYIFAGTT
YTGFKNPIGVPMIPISQAYVDFNGYFQNAFGFPYLYRGVYIRNEYPGSVPIYFSPLVYEPGWGLWYVFQNKTYRISTNVN
WIIPNTTEVTIDGAGAQSIDDLIGQFLINIDYSKLQKSGTYVGLVYIDDPDTSYIDGYIAVTVDIPVNPNGESYAKLSDT
EKPGEAKHYFVKVPRGTKELRVTLRIATDAEGNPIGRTTLLIARPLGEVVAAYVPGYYYVGANPAGNVYEYTWVIPDPVE
GTWEITAYSSVFTKYFSGYDTSQYEIEVNISSVTITPELISGYLTTPTNISVSAIVENNYDNFNATAVGYGLGRLDTNDV
MVRNVGQDEWDLIGAFYADPTTYFIRFGITQPKDPTADLDLYVFYFPTYEDLLNFTNYTIYDYQIGPTSDEVFEQFMPAP
GYYVVNVHGYDTVGYDQLQYVFYYQILGDNGDISTGESPFLFEMGTNRTINATIEFSANGTYLGILGLINADTGEGITYA
PTMFQVGQPEMVIVAYPEATLGKPSVLKIRLLDLATMDPIAVPVAVSINGQEYYTSTGVLDISYVPLHRTETFRIQVISD
YYKDTYTEITVRAKEPVENEVYSPTILEPYVAVGVGEVTGVTTDETMLTITANGPSGAEDYIFVTLPVDTSYIKITGDHI
IDYYTIEGKNALYAVIKVKYASPVTVTIEYKTARYIVSTWNYVWYMLYWRYNQKFDPLYQKAVELGVDNKTLQEAMRYKE
LADEYYAEAKKYMNPYRENLAVAALPYVRKAYLNILKAYTLLEEAVNEIEGSEG
>Mature_1414_residues
MNKKALSLLVVVVMLLSAIPAAVSVLAVTATPVQQSESPQQIEVEKPSNFIPGEVLQKEIQKVLESSGKTVRLIVAPDRD
HRTEVYNALKSLGKIDPISKPELQFIVVEMPVSNVEKLAEIPGILHVWKDEMVKLEEPVAPEAGAGDVSPDASFPTHPDM
FMSIFTIHAYDTWVNYGVLGDNVTVAVLDTGIDVGHPFLQVTLDGRPKIVNIYDASDEGLAEIYYSTNTTSSGYITVDKN
VTLFWGVYAPYYGHDAYYTNYTMGTYYIGNITGDMYYIGLLPERYFDLNFDGDKNDVYPILVVDNNGTYTAYMDINMNNN
FTDDTGVGLYTETGEYFTFNTSLVNVAFAEFMAPYYAMFMWDAHGHGTHVSGTVAGVGLPDDPLFGGVYGVAPNAQLMEV
KVLPGEFGFGRTSWIIGGMIYATLNGADVISMSLGGGGEINDGIESPENFYVNLLTDWYGVTFAIAAGNEGPTTNTVHSP
GDSDLAITVGNYVDNERESFWYGVDMGIISGPAMSSSRGPRDDGMLDPDVMAPGTDIFSSLPMWYTIVYNDSNRYYGIWS
GTSMATPHVSGAVALMISYAKQHNLTYDPIMIKRALELSAKPVNGTLIDQGFGLIQVDKAIEELEKLSQEPTTYIFAGTT
YTGFKNPIGVPMIPISQAYVDFNGYFQNAFGFPYLYRGVYIRNEYPGSVPIYFSPLVYEPGWGLWYVFQNKTYRISTNVN
WIIPNTTEVTIDGAGAQSIDDLIGQFLINIDYSKLQKSGTYVGLVYIDDPDTSYIDGYIAVTVDIPVNPNGESYAKLSDT
EKPGEAKHYFVKVPRGTKELRVTLRIATDAEGNPIGRTTLLIARPLGEVVAAYVPGYYYVGANPAGNVYEYTWVIPDPVE
GTWEITAYSSVFTKYFSGYDTSQYEIEVNISSVTITPELISGYLTTPTNISVSAIVENNYDNFNATAVGYGLGRLDTNDV
MVRNVGQDEWDLIGAFYADPTTYFIRFGITQPKDPTADLDLYVFYFPTYEDLLNFTNYTIYDYQIGPTSDEVFEQFMPAP
GYYVVNVHGYDTVGYDQLQYVFYYQILGDNGDISTGESPFLFEMGTNRTINATIEFSANGTYLGILGLINADTGEGITYA
PTMFQVGQPEMVIVAYPEATLGKPSVLKIRLLDLATMDPIAVPVAVSINGQEYYTSTGVLDISYVPLHRTETFRIQVISD
YYKDTYTEITVRAKEPVENEVYSPTILEPYVAVGVGEVTGVTTDETMLTITANGPSGAEDYIFVTLPVDTSYIKITGDHI
IDYYTIEGKNALYAVIKVKYASPVTVTIEYKTARYIVSTWNYVWYMLYWRYNQKFDPLYQKAVELGVDNKTLQEAMRYKE
LADEYYAEAKKYMNPYRENLAVAALPYVRKAYLNILKAYTLLEEAVNEIEGSEG

Specific function: Has endopeptidase activity toward caseins, casein fragments including alpha-S1-casein and synthetic peptides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cell envelope. Note=Cell envelope associated [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI186972143, Length=722, Percent_Identity=25.3462603878116, Blast_Score=144, Evalue=8e-34,
Organism=Homo sapiens, GI4506775, Length=266, Percent_Identity=29.3233082706767, Blast_Score=75, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17533391, Length=791, Percent_Identity=23.8938053097345, Blast_Score=121, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320775, Length=232, Percent_Identity=31.8965517241379, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24653270, Length=275, Percent_Identity=34.5454545454545, Blast_Score=106, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17137360, Length=275, Percent_Identity=34.5454545454545, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45550681, Length=272, Percent_Identity=27.5735294117647, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 156944; Mature: 156944

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKALSLLVVVVMLLSAIPAAVSVLAVTATPVQQSESPQQIEVEKPSNFIPGEVLQKEI
CCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHH
QKVLESSGKTVRLIVAPDRDHRTEVYNALKSLGKIDPISKPELQFIVVEMPVSNVEKLAE
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHH
IPGILHVWKDEMVKLEEPVAPEAGAGDVSPDASFPTHPDMFMSIFTIHAYDTWVNYGVLG
CCCEEEECCHHHEEECCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEHEEEEEEEC
DNVTVAVLDTGIDVGHPFLQVTLDGRPKIVNIYDASDEGLAEIYYSTNTTSSGYITVDKN
CCEEEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCC
VTLFWGVYAPYYGHDAYYTNYTMGTYYIGNITGDMYYIGLLPERYFDLNFDGDKNDVYPI
EEEEEEECCCCCCCCCEEEEEEEEEEEEEEECCCEEEEEECCCCEEEEECCCCCCCEEEE
LVVDNNGTYTAYMDINMNNNFTDDTGVGLYTETGEYFTFNTSLVNVAFAEFMAPYYAMFM
EEEECCCCEEEEEEEECCCCCCCCCCCEEEEECCCEEEEECHHHHHHHHHHHHCEEEEEE
WDAHGHGTHVSGTVAGVGLPDDPLFGGVYGVAPNAQLMEVKVLPGEFGFGRTSWIIGGMI
EECCCCCCEECCEEEECCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCHHHEECEEE
YATLNGADVISMSLGGGGEINDGIESPENFYVNLLTDWYGVTFAIAAGNEGPTTNTVHSP
EEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCC
GDSDLAITVGNYVDNERESFWYGVDMGIISGPAMSSSRGPRDDGMLDPDVMAPGTDIFSS
CCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHC
LPMWYTIVYNDSNRYYGIWSGTSMATPHVSGAVALMISYAKQHNLTYDPIMIKRALELSA
CCEEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHEEHHHHHCCCCCCHHHHHHHHHCCC
KPVNGTLIDQGFGLIQVDKAIEELEKLSQEPTTYIFAGTTYTGFKNPIGVPMIPISQAYV
CCCCCEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEECCEECCCCCCCCCCEEECCEEEE
DFNGYFQNAFGFPYLYRGVYIRNEYPGSVPIYFSPLVYEPGWGLWYVFQNKTYRISTNVN
EECCEECCCCCCCCHHCCEEEECCCCCCCCEEEECEEECCCCCEEEEEECCEEEEECCEE
WIIPNTTEVTIDGAGAQSIDDLIGQFLINIDYSKLQKSGTYVGLVYIDDPDTSYIDGYIA
EEECCCEEEEEECCCCCHHHHHHHHHEEECCHHHHHCCCCEEEEEEECCCCCCEECEEEE
VTVDIPVNPNGESYAKLSDTEKPGEAKHYFVKVPRGTKELRVTLRIATDAEGNPIGRTTL
EEEEEECCCCCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCEEE
LIARPLGEVVAAYVPGYYYVGANPAGNVYEYTWVIPDPVEGTWEITAYSSVFTKYFSGYD
EEECCHHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHCCCC
TSQYEIEVNISSVTITPELISGYLTTPTNISVSAIVENNYDNFNATAVGYGLGRLDTNDV
CCEEEEEEEEEEEEEEHHHHCCEECCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCE
MVRNVGQDEWDLIGAFYADPTTYFIRFGITQPKDPTADLDLYVFYFPTYEDLLNFTNYTI
EEEECCCCCHHEEEEEECCCEEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHCCCCEEE
YDYQIGPTSDEVFEQFMPAPGYYVVNVHGYDTVGYDQLQYVFYYQILGDNGDISTGESPF
EEEEECCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCE
LFEMGTNRTINATIEFSANGTYLGILGLINADTGEGITYAPTMFQVGQPEMVIVAYPEAT
EEECCCCCEEEEEEEECCCCEEEEEEEEEECCCCCCEEECCCEEECCCCCEEEEECCCCC
LGKPSVLKIRLLDLATMDPIAVPVAVSINGQEYYTSTGVLDISYVPLHRTETFRIQVISD
CCCCCEEEEEEEEECCCCCEEEEEEEEECCCEEEEECCEEEEEEEECCCCCEEEEEEEEH
YYKDTYTEITVRAKEPVENEVYSPTILEPYVAVGVGEVTGVTTDETMLTITANGPSGAED
HHCCCEEEEEEEECCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCEEEEEEECCCCCCCC
YIFVTLPVDTSYIKITGDHIIDYYTIEGKNALYAVIKVKYASPVTVTIEYKTARYIVSTW
EEEEEEECCCCEEEEECCEEEEEEEECCCCEEEEEEEEEECCCEEEEEEEEEEEEEEEHH
NYVWYMLYWRYNQKFDPLYQKAVELGVDNKTLQEAMRYKELADEYYAEAKKYMNPYRENL
CEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCE
AVAALPYVRKAYLNILKAYTLLEEAVNEIEGSEG
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKKALSLLVVVVMLLSAIPAAVSVLAVTATPVQQSESPQQIEVEKPSNFIPGEVLQKEI
CCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCEEEEECCCCCCCHHHHHHHH
QKVLESSGKTVRLIVAPDRDHRTEVYNALKSLGKIDPISKPELQFIVVEMPVSNVEKLAE
HHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHH
IPGILHVWKDEMVKLEEPVAPEAGAGDVSPDASFPTHPDMFMSIFTIHAYDTWVNYGVLG
CCCEEEECCHHHEEECCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEHEEEEEEEC
DNVTVAVLDTGIDVGHPFLQVTLDGRPKIVNIYDASDEGLAEIYYSTNTTSSGYITVDKN
CCEEEEEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEECCC
VTLFWGVYAPYYGHDAYYTNYTMGTYYIGNITGDMYYIGLLPERYFDLNFDGDKNDVYPI
EEEEEEECCCCCCCCCEEEEEEEEEEEEEEECCCEEEEEECCCCEEEEECCCCCCCEEEE
LVVDNNGTYTAYMDINMNNNFTDDTGVGLYTETGEYFTFNTSLVNVAFAEFMAPYYAMFM
EEEECCCCEEEEEEEECCCCCCCCCCCEEEEECCCEEEEECHHHHHHHHHHHHCEEEEEE
WDAHGHGTHVSGTVAGVGLPDDPLFGGVYGVAPNAQLMEVKVLPGEFGFGRTSWIIGGMI
EECCCCCCEECCEEEECCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCHHHEECEEE
YATLNGADVISMSLGGGGEINDGIESPENFYVNLLTDWYGVTFAIAAGNEGPTTNTVHSP
EEEECCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCC
GDSDLAITVGNYVDNERESFWYGVDMGIISGPAMSSSRGPRDDGMLDPDVMAPGTDIFSS
CCCCEEEEECCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHC
LPMWYTIVYNDSNRYYGIWSGTSMATPHVSGAVALMISYAKQHNLTYDPIMIKRALELSA
CCEEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHEEHHHHHCCCCCCHHHHHHHHHCCC
KPVNGTLIDQGFGLIQVDKAIEELEKLSQEPTTYIFAGTTYTGFKNPIGVPMIPISQAYV
CCCCCEEEECCCCEEEHHHHHHHHHHHHCCCCEEEEECCEECCCCCCCCCCEEECCEEEE
DFNGYFQNAFGFPYLYRGVYIRNEYPGSVPIYFSPLVYEPGWGLWYVFQNKTYRISTNVN
EECCEECCCCCCCCHHCCEEEECCCCCCCCEEEECEEECCCCCEEEEEECCEEEEECCEE
WIIPNTTEVTIDGAGAQSIDDLIGQFLINIDYSKLQKSGTYVGLVYIDDPDTSYIDGYIA
EEECCCEEEEEECCCCCHHHHHHHHHEEECCHHHHHCCCCEEEEEEECCCCCCEECEEEE
VTVDIPVNPNGESYAKLSDTEKPGEAKHYFVKVPRGTKELRVTLRIATDAEGNPIGRTTL
EEEEEECCCCCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEEEEEEECCCCCCCCCEEE
LIARPLGEVVAAYVPGYYYVGANPAGNVYEYTWVIPDPVEGTWEITAYSSVFTKYFSGYD
EEECCHHHHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHCCCC
TSQYEIEVNISSVTITPELISGYLTTPTNISVSAIVENNYDNFNATAVGYGLGRLDTNDV
CCEEEEEEEEEEEEEEHHHHCCEECCCCCEEEEEEEECCCCCCCEEEEEEECCCCCCCCE
MVRNVGQDEWDLIGAFYADPTTYFIRFGITQPKDPTADLDLYVFYFPTYEDLLNFTNYTI
EEEECCCCCHHEEEEEECCCEEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHCCCCEEE
YDYQIGPTSDEVFEQFMPAPGYYVVNVHGYDTVGYDQLQYVFYYQILGDNGDISTGESPF
EEEEECCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEEEEECCCCCCCCCCCCE
LFEMGTNRTINATIEFSANGTYLGILGLINADTGEGITYAPTMFQVGQPEMVIVAYPEAT
EEECCCCCEEEEEEEECCCCEEEEEEEEEECCCCCCEEECCCEEECCCCCEEEEECCCCC
LGKPSVLKIRLLDLATMDPIAVPVAVSINGQEYYTSTGVLDISYVPLHRTETFRIQVISD
CCCCCEEEEEEEEECCCCCEEEEEEEEECCCEEEEECCEEEEEEEECCCCCEEEEEEEEH
YYKDTYTEITVRAKEPVENEVYSPTILEPYVAVGVGEVTGVTTDETMLTITANGPSGAED
HHCCCEEEEEEEECCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCEEEEEEECCCCCCCC
YIFVTLPVDTSYIKITGDHIIDYYTIEGKNALYAVIKVKYASPVTVTIEYKTARYIVSTW
EEEEEEECCCCEEEEECCEEEEEEEECCCCEEEEEEEEEECCCEEEEEEEEEEEEEEEHH
NYVWYMLYWRYNQKFDPLYQKAVELGVDNKTLQEAMRYKELADEYYAEAKKYMNPYRENL
CEEEEEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCE
AVAALPYVRKAYLNILKAYTLLEEAVNEIEGSEG
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8702780; 11210516 [H]