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The map label for this gene is glkA [H]

Identifier: 212223392

GI number: 212223392

Start: 220672

End: 222033

Strand: Reverse

Name: glkA [H]

Synonym: TON_0246

Alternate gene names: 212223392

Gene position: 222033-220672 (Counterclockwise)

Preceding gene: 212223393

Following gene: 212223391

Centisome position: 12.02

GC content: 53.96

Gene sequence:

>1362_bases
ATGATGTGGGACGCTCTCTACTCATCGGCTTTTCAGCGCGTCAAGGATAAAATCGGAAAAGTCGGCAGCGTTCTTCTTGC
GTACAATACCAACATCGACGCGATAAAGTACCTCGATTCGGAAGATCTTGAGGGAAGGGTGGAGAAGGTTGGAAAGGAAG
AGGTTTTCTGCTTTTCTGAGGAGCTTCCCGGAAGGATAACGAAGATTCATCACCTTCTCGGTGGAATCCTCTGGAGCATT
CGGAGGGGAAAGGCCGCTGAACTCTTCGTCGAGAGCTGCACGGTCAGGCTCTACATGAAGAACTGGGGCTGGGACGAACT
CAGGATGGGCGGCCAGGTCGGAATAATGGCCAACCTCCTCGGTGGTGTTTACGGCGTTCCAGTTATAGCGCACGTTCCGC
AGATATCAAAGCTCCAGGCGAACCTGTTCAAGGACGGACCGATTTACGTGCCGAAGCTCGAGGATGGAAAGCTCAAGCTC
CTCCACCCCAGAGAGTTCGCCGGCGACGAGGAGAACCTTATCCACTACATCTATGAGTTCCCGCGCGGATTCAGGGTTTT
CGACTTCGAGGCCCCGAGGGAGAACCGCTTCATAGGATCCGCTGATGACTACAATCCAAACGTCTACATAAGGCCTGAGT
TTAGGGAAGCCTTCGAGGAGATAGCTGGAAAGGCCGAGCTGGTGATAATAAGCGGACTCCAAGCTTTGACGAAGGAGAAC
TACAAAGAACCCTTTGAAGAGCTTGAGAGGCACCTTGAGGTGCTTGACGAGAGGGGAATTCCCGTTCACCTGGAGTTCGC
CTTCACGCCAGACGAGACCGTCAGAAGGAGGCTCGTCGAGATTCTGGGCAAGTTCACGAGCGTTGGCCTGAATGAGGTCG
AGCTGGCCTCGATAATGGAGGTTCTTGGCGAGAAAGCCATAGCAGAGAAGCTTCTTGCAAACGACCCAGTTGATCCGATA
GCTGTTACGGAGGCCATGCTCAAGCTGGCGGAGAAGACCGGCGTTGAGAGGATACACTTCCACACTTACGGCTATTACTT
GGCTTTGACTGCCTACGATGGAACCCATGTGCGCGATGCCCTGCTCTTTGCGGCCCTAGCCGCCGCAGCCAGGGCTAAAC
TTGGTGACGTTAGAGACATAGACGACGTGGTTAAGGCCATGGACGTTCCAGTTAACGAGAAGGTCAGAGCCGTCGAGGGG
GCTCTCGTTAGGGAGTATGGCACGGAGGATGGCATTGCTAAAGTCGACGACTATCAGCTTGCATTTGTCCCGACCAAGAT
AGTCACCAAGCCCAAGAGCACAGTTGGCATTGGTGACACGATTTCCAGTTCCGCCTTCATCGGGGAATTCGCCCTTCGCT
GA

Upstream 100 bases:

>100_bases
TTGACAATCCCAAGTGGAAAGCATGAGCCTCTTCTTAATTTTTAACGTTCACCGCAACCCTTATTAACTTCCAGGAGTTA
CATCACTCCCGGTGATATAC

Downstream 100 bases:

>100_bases
GTTTTCCTTCTTTCCCCTTAAAGTTAAAAACTTTGGATGCTAAAAGGATTCAGAGCTAAACTAAGGTGGTGCCCAATGAA
GACTCTGATTCTTGCCGGTG

Product: ADP-dependent glucokinase

Products: NA

Alternate protein names: ADP-GK; ADPGK [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MMWDALYSSAFQRVKDKIGKVGSVLLAYNTNIDAIKYLDSEDLEGRVEKVGKEEVFCFSEELPGRITKIHHLLGGILWSI
RRGKAAELFVESCTVRLYMKNWGWDELRMGGQVGIMANLLGGVYGVPVIAHVPQISKLQANLFKDGPIYVPKLEDGKLKL
LHPREFAGDEENLIHYIYEFPRGFRVFDFEAPRENRFIGSADDYNPNVYIRPEFREAFEEIAGKAELVIISGLQALTKEN
YKEPFEELERHLEVLDERGIPVHLEFAFTPDETVRRRLVEILGKFTSVGLNEVELASIMEVLGEKAIAEKLLANDPVDPI
AVTEAMLKLAEKTGVERIHFHTYGYYLALTAYDGTHVRDALLFAALAAAARAKLGDVRDIDDVVKAMDVPVNEKVRAVEG
ALVREYGTEDGIAKVDDYQLAFVPTKIVTKPKSTVGIGDTISSSAFIGEFALR

Sequences:

>Translated_453_residues
MMWDALYSSAFQRVKDKIGKVGSVLLAYNTNIDAIKYLDSEDLEGRVEKVGKEEVFCFSEELPGRITKIHHLLGGILWSI
RRGKAAELFVESCTVRLYMKNWGWDELRMGGQVGIMANLLGGVYGVPVIAHVPQISKLQANLFKDGPIYVPKLEDGKLKL
LHPREFAGDEENLIHYIYEFPRGFRVFDFEAPRENRFIGSADDYNPNVYIRPEFREAFEEIAGKAELVIISGLQALTKEN
YKEPFEELERHLEVLDERGIPVHLEFAFTPDETVRRRLVEILGKFTSVGLNEVELASIMEVLGEKAIAEKLLANDPVDPI
AVTEAMLKLAEKTGVERIHFHTYGYYLALTAYDGTHVRDALLFAALAAAARAKLGDVRDIDDVVKAMDVPVNEKVRAVEG
ALVREYGTEDGIAKVDDYQLAFVPTKIVTKPKSTVGIGDTISSSAFIGEFALR
>Mature_453_residues
MMWDALYSSAFQRVKDKIGKVGSVLLAYNTNIDAIKYLDSEDLEGRVEKVGKEEVFCFSEELPGRITKIHHLLGGILWSI
RRGKAAELFVESCTVRLYMKNWGWDELRMGGQVGIMANLLGGVYGVPVIAHVPQISKLQANLFKDGPIYVPKLEDGKLKL
LHPREFAGDEENLIHYIYEFPRGFRVFDFEAPRENRFIGSADDYNPNVYIRPEFREAFEEIAGKAELVIISGLQALTKEN
YKEPFEELERHLEVLDERGIPVHLEFAFTPDETVRRRLVEILGKFTSVGLNEVELASIMEVLGEKAIAEKLLANDPVDPI
AVTEAMLKLAEKTGVERIHFHTYGYYLALTAYDGTHVRDALLFAALAAAARAKLGDVRDIDDVVKAMDVPVNEKVRAVEG
ALVREYGTEDGIAKVDDYQLAFVPTKIVTKPKSTVGIGDTISSSAFIGEFALR

Specific function: Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor [H]

COG id: COG4809

COG function: function code G; Archaeal ADP-dependent phosphofructokinase/glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ADPK (ADP-dependent kinase) domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI32564831, Length=314, Percent_Identity=24.5222929936306, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007666
- InterPro:   IPR015990 [H]

Pfam domain/function: PF04587 ADP_PFK_GK [H]

EC number: =2.7.1.147 [H]

Molecular weight: Translated: 50744; Mature: 50744

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMWDALYSSAFQRVKDKIGKVGSVLLAYNTNIDAIKYLDSEDLEGRVEKVGKEEVFCFSE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCHHHHHCCCHHEEEECC
ELPGRITKIHHLLGGILWSIRRGKAAELFVESCTVRLYMKNWGWDELRMGGQVGIMANLL
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCHHHHHCCCCHHHHHHHH
GGVYGVPVIAHVPQISKLQANLFKDGPIYVPKLEDGKLKLLHPREFAGDEENLIHYIYEF
HHHHCCCHHHHCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCHHHCCCHHHHHHHHHHC
PRGFRVFDFEAPRENRFIGSADDYNPNVYIRPEFREAFEEIAGKAELVIISGLQALTKEN
CCCCEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCEEEEEEECHHHHHHHH
YKEPFEELERHLEVLDERGIPVHLEFAFTPDETVRRRLVEILGKFTSVGLNEVELASIME
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VLGEKAIAEKLLANDPVDPIAVTEAMLKLAEKTGVERIHFHTYGYYLALTAYDGTHVRDA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCHHHHH
LLFAALAAAARAKLGDVRDIDDVVKAMDVPVNEKVRAVEGALVREYGTEDGIAKVDDYQL
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEE
AFVPTKIVTKPKSTVGIGDTISSSAFIGEFALR
EEECHHHCCCCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MMWDALYSSAFQRVKDKIGKVGSVLLAYNTNIDAIKYLDSEDLEGRVEKVGKEEVFCFSE
CCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCCCCCHHHHHCCCHHEEEECC
ELPGRITKIHHLLGGILWSIRRGKAAELFVESCTVRLYMKNWGWDELRMGGQVGIMANLL
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCHHHHHCCCCHHHHHHHH
GGVYGVPVIAHVPQISKLQANLFKDGPIYVPKLEDGKLKLLHPREFAGDEENLIHYIYEF
HHHHCCCHHHHCCCHHHHHHHHCCCCCEEEEECCCCCEEEECCHHHCCCHHHHHHHHHHC
PRGFRVFDFEAPRENRFIGSADDYNPNVYIRPEFREAFEEIAGKAELVIISGLQALTKEN
CCCCEEEEECCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHCCCEEEEEEECHHHHHHHH
YKEPFEELERHLEVLDERGIPVHLEFAFTPDETVRRRLVEILGKFTSVGLNEVELASIME
HHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
VLGEKAIAEKLLANDPVDPIAVTEAMLKLAEKTGVERIHFHTYGYYLALTAYDGTHVRDA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCHHHHH
LLFAALAAAARAKLGDVRDIDDVVKAMDVPVNEKVRAVEGALVREYGTEDGIAKVDDYQL
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEE
AFVPTKIVTKPKSTVGIGDTISSSAFIGEFALR
EEECHHHCCCCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA