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The map label for this gene is xanB [H]

Identifier: 212223391

GI number: 212223391

Start: 219214

End: 220596

Strand: Reverse

Name: xanB [H]

Synonym: TON_0245

Alternate gene names: 212223391

Gene position: 220596-219214 (Counterclockwise)

Preceding gene: 212223392

Following gene: 212223390

Centisome position: 11.94

GC content: 49.75

Gene sequence:

>1383_bases
ATGAAGACTCTGATTCTTGCCGGTGGTAAGGGAACTCGCCTCTGGCCCCTGAGCAGGGAGCTGATGCCAAAGCAGTTCAT
AAGGATGTTTGATGACTATTCCCTCTTTCAGAAAACGATTCAGAGGGCGTTGATGTTCTCAAAACCAAACGAAATATTCA
TCGTGACTAATGAGAAGTACAAGTTTCGTATTCTTGACGATTTAAGAGAGCTCGGCCTGGAGCTCCCAGAAGAGAACCTC
CTCCTTGAGCCCGTAGGAAAGAACACTCTCCCTGCCATTTACTGGGGAATAATGAGAATCGAAGAAATCTTCGGAGACTC
CATTGTGGCGGTCCTCCCGTCGGATCACCTGATAGAAGCGGATAAGAACTACGAGAAAGCCTTCAGGAATGCTGAGAGGA
TTGCTCATGATTACCTCGTAACCTTCGGAATAAAACCAACGAGGCCGCACACCGGCTATGGCTACATAAAGCCAGGGGAA
CGGCTTGAAGGTGGCTACCGCGTTGCTGAGTTCAAGGAGAAGCCGGATTTGAAGACTGCCAAACGCTACGTTGAGGAAGG
CTATTACTGGAACAGCGGCATGTTTATGTTCGATACTGAGCTCTTCATTGATGAAGTGAAGAGGCTAGCTCCCGAAATCT
ACTCTGCTTTTGAAGAGGCTGCGACTATCCGGGAAGCCTACGAACGGGTTCAGGATATCTCCGTTGACTACGGGATAATG
GAGAAAACTGATAAAGCCGCCGTCGTCCCTCTCAACGTCTACTGGAATGATCTCGGGAGCTTCGACGCTATCTACGAGGT
TCTTGAGAAGGACAAAAACGGCAACGCTGTGAAGATACGGGGAAGGAAGGGCTATCACGTCGGTATCGATTCGAGGAACA
ACCTCATAATGACGGAGCGTTTGACCGCTACAGTTGGTGTTGAGGATCTGATAATCATTGATACTGATGATGCCCTCCTC
GTCGCCCATCGCGGTGATAGTCAGAAAGTCAAGGAGGTTTACAAAAGGCTTAAGGATAAGGGTGATGAGAGGGTCTTTGT
TCATAGAACCGCTTATCGTCCCTGGGGAAGCTACACTATCCTCGAGGAGGGCGAGCGCTACAAGATAAAGCGTCTGACAG
TTCTGCCTGGCAAAAAGCTTTCCCTGCAGATGCACTATCACAGGAGCGAGCACTGGGTCGTTGTAAGGGGAACGGCCAAG
GTTTTCATTGACGGTGAGGAGATACTCCTCAGACCGGGGGAGAGCACTTTCATTCCCGCGGGCGTAGTTCACAGGCTTGA
GAACCCCGGAAAGGTCGTCCTTGAGGTCATTGAAACGCAGATAGGAGAATACCTTGGTGAGGATGACATAGTCCGCTTTG
ATGATGATTTTGGGAGGGAATGA

Upstream 100 bases:

>100_bases
CATCGGGGAATTCGCCCTTCGCTGAGTTTTCCTTCTTTCCCCTTAAAGTTAAAAACTTTGGATGCTAAAAGGATTCAGAG
CTAAACTAAGGTGGTGCCCA

Downstream 100 bases:

>100_bases
GATGGGAAAGCTGTTTGGAACCTTCGGCGTCAGGGGAATAGCCAACGAGAAGATAACCCCAGAGTTCGCGCTTAAGATGG
GCATGGCCTTCGGAACGATG

Product: bifunctional mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKTLILAGGKGTRLWPLSRELMPKQFIRMFDDYSLFQKTIQRALMFSKPNEIFIVTNEKYKFRILDDLRELGLELPEENL
LLEPVGKNTLPAIYWGIMRIEEIFGDSIVAVLPSDHLIEADKNYEKAFRNAERIAHDYLVTFGIKPTRPHTGYGYIKPGE
RLEGGYRVAEFKEKPDLKTAKRYVEEGYYWNSGMFMFDTELFIDEVKRLAPEIYSAFEEAATIREAYERVQDISVDYGIM
EKTDKAAVVPLNVYWNDLGSFDAIYEVLEKDKNGNAVKIRGRKGYHVGIDSRNNLIMTERLTATVGVEDLIIIDTDDALL
VAHRGDSQKVKEVYKRLKDKGDERVFVHRTAYRPWGSYTILEEGERYKIKRLTVLPGKKLSLQMHYHRSEHWVVVRGTAK
VFIDGEEILLRPGESTFIPAGVVHRLENPGKVVLEVIETQIGEYLGEDDIVRFDDDFGRE

Sequences:

>Translated_460_residues
MKTLILAGGKGTRLWPLSRELMPKQFIRMFDDYSLFQKTIQRALMFSKPNEIFIVTNEKYKFRILDDLRELGLELPEENL
LLEPVGKNTLPAIYWGIMRIEEIFGDSIVAVLPSDHLIEADKNYEKAFRNAERIAHDYLVTFGIKPTRPHTGYGYIKPGE
RLEGGYRVAEFKEKPDLKTAKRYVEEGYYWNSGMFMFDTELFIDEVKRLAPEIYSAFEEAATIREAYERVQDISVDYGIM
EKTDKAAVVPLNVYWNDLGSFDAIYEVLEKDKNGNAVKIRGRKGYHVGIDSRNNLIMTERLTATVGVEDLIIIDTDDALL
VAHRGDSQKVKEVYKRLKDKGDERVFVHRTAYRPWGSYTILEEGERYKIKRLTVLPGKKLSLQMHYHRSEHWVVVRGTAK
VFIDGEEILLRPGESTFIPAGVVHRLENPGKVVLEVIETQIGEYLGEDDIVRFDDDFGRE
>Mature_460_residues
MKTLILAGGKGTRLWPLSRELMPKQFIRMFDDYSLFQKTIQRALMFSKPNEIFIVTNEKYKFRILDDLRELGLELPEENL
LLEPVGKNTLPAIYWGIMRIEEIFGDSIVAVLPSDHLIEADKNYEKAFRNAERIAHDYLVTFGIKPTRPHTGYGYIKPGE
RLEGGYRVAEFKEKPDLKTAKRYVEEGYYWNSGMFMFDTELFIDEVKRLAPEIYSAFEEAATIREAYERVQDISVDYGIM
EKTDKAAVVPLNVYWNDLGSFDAIYEVLEKDKNGNAVKIRGRKGYHVGIDSRNNLIMTERLTATVGVEDLIIIDTDDALL
VAHRGDSQKVKEVYKRLKDKGDERVFVHRTAYRPWGSYTILEEGERYKIKRLTVLPGKKLSLQMHYHRSEHWVVVRGTAK
VFIDGEEILLRPGESTFIPAGVVHRLENPGKVVLEVIETQIGEYLGEDDIVRFDDDFGRE

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=477, Percent_Identity=43.3962264150943, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 53166; Mature: 53166

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLILAGGKGTRLWPLSRELMPKQFIRMFDDYSLFQKTIQRALMFSKPNEIFIVTNEKY
CCEEEEECCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCE
KFRILDDLRELGLELPEENLLLEPVGKNTLPAIYWGIMRIEEIFGDSIVAVLPSDHLIEA
EEEEHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEC
DKNYEKAFRNAERIAHDYLVTFGIKPTRPHTGYGYIKPGERLEGGYRVAEFKEKPDLKTA
CCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHH
KRYVEEGYYWNSGMFMFDTELFIDEVKRLAPEIYSAFEEAATIREAYERVQDISVDYGIM
HHHHHCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKTDKAAVVPLNVYWNDLGSFDAIYEVLEKDKNGNAVKIRGRKGYHVGIDSRNNLIMTER
CCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCEEEEEE
LTATVGVEDLIIIDTDDALLVAHRGDSQKVKEVYKRLKDKGDERVFVHRTAYRPWGSYTI
EEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEE
LEEGERYKIKRLTVLPGKKLSLQMHYHRSEHWVVVRGTAKVFIDGEEILLRPGESTFIPA
EECCCEEEEEEEEECCCCCEEEEEEEECCCCEEEEEECEEEEECCCEEEEECCCCCEECH
GVVHRLENPGKVVLEVIETQIGEYLGEDDIVRFDDDFGRE
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHCCCC
>Mature Secondary Structure
MKTLILAGGKGTRLWPLSRELMPKQFIRMFDDYSLFQKTIQRALMFSKPNEIFIVTNEKY
CCEEEEECCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCE
KFRILDDLRELGLELPEENLLLEPVGKNTLPAIYWGIMRIEEIFGDSIVAVLPSDHLIEA
EEEEHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEC
DKNYEKAFRNAERIAHDYLVTFGIKPTRPHTGYGYIKPGERLEGGYRVAEFKEKPDLKTA
CCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHH
KRYVEEGYYWNSGMFMFDTELFIDEVKRLAPEIYSAFEEAATIREAYERVQDISVDYGIM
HHHHHCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EKTDKAAVVPLNVYWNDLGSFDAIYEVLEKDKNGNAVKIRGRKGYHVGIDSRNNLIMTER
CCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEECCCCCCEEEEEE
LTATVGVEDLIIIDTDDALLVAHRGDSQKVKEVYKRLKDKGDERVFVHRTAYRPWGSYTI
EEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCEEE
LEEGERYKIKRLTVLPGKKLSLQMHYHRSEHWVVVRGTAKVFIDGEEILLRPGESTFIPA
EECCCEEEEEEEEECCCCCEEEEEEEECCCCEEEEEECEEEEECCCEEEEECCCCCEECH
GVVHRLENPGKVVLEVIETQIGEYLGEDDIVRFDDDFGRE
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]