Click here to switch to the map view.

The map label for this gene is udk [H]

Identifier: 209554622

GI number: 209554622

Start: 377098

End: 377721

Strand: Reverse

Name: udk [H]

Synonym: UUR10_0339

Alternate gene names: 209554622

Gene position: 377721-377098 (Counterclockwise)

Preceding gene: 209554630

Following gene: 209554105

Centisome position: 43.19

GC content: 29.33

Gene sequence:

>624_bases
ATGAATGCTAAATCCCCGATTCTTGTATTAATTGCAGGTGCTTCTGGCTCTGGAAAGACAACTTTTGCCAATGAAATTGT
TGCAAGAATTCCTCAAAATACAACAAGCGTTATTATTTGTCAAGACTCTTATTATATTTCTAATTCACAATTAAATAAAA
ACGAGCGTCGTTTAATTAATTATGATCATCCAAGTAGTTTTGAATGAGATTTAATGCGAGAGCAATTAAGTGACATTAAA
AAACGTAAAAAAATTAAAGTACCAATCTATGATTATAAAACTGAGATTCGCTTAGATAAAACAATTGATATTAGTGATGT
TGATGTTATAGTTTTTGAAGGTATTTATGCGATTTATGATGATGTCATTAATCAAATAGCTGATTTAAAAGTTTTTATTG
AAACACCAAAAGATGAATGTTTAATTCGGCGAATCCTTCGAGATGTTAACGAACGTAATCGATCATTTGAATCTGTAATT
ACTCAATGACGTAGCACTGTTAGCCCTATGTATGATCAATTTGTTGAGCCAAGTAAAAAGAATGCTAATGTTAGTGTGCT
ATGAAATGAACACAATCGTGTTGCATTACATTTAATTAATAAATGAATCAATAATATACATTAA

Upstream 100 bases:

>100_bases
TTTTAATATCTTTTTTTTATAAAATTGTTGGAATAATGAAACCAACTCCTACACATAATCTATAATAGTAATATGTTTAA
ATAATTTAAGGCTTTAAAAT

Downstream 100 bases:

>100_bases
AATATAGCAATTAATTTAATTTTAAATTATGTCATATTATTATAAAAGTAAATTTAGAATTACAGATCATGCATTAGCTC
GTTTTCGAGAACGTGCAGCA

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNAKSPILVLIAGASGSGKTTFANEIVARIPQNTTSVIICQDSYYISNSQLNKNERRLINYDHPSSFEWDLMREQLSDIK
KRKKIKVPIYDYKTEIRLDKTIDISDVDVIVFEGIYAIYDDVINQIADLKVFIETPKDECLIRRILRDVNERNRSFESVI
TQWRSTVSPMYDQFVEPSKKNANVSVLWNEHNRVALHLINKWINNIH

Sequences:

>Translated_207_residues
MNAKSPILVLIAGASGSGKTTFANEIVARIPQNTTSVIICQDSYYISNSQLNKNERRLINYDHPSSFE*DLMREQLSDIK
KRKKIKVPIYDYKTEIRLDKTIDISDVDVIVFEGIYAIYDDVINQIADLKVFIETPKDECLIRRILRDVNERNRSFESVI
TQ*RSTVSPMYDQFVEPSKKNANVSVL*NEHNRVALHLINK*INNIH
>Mature_207_residues
MNAKSPILVLIAGASGSGKTTFANEIVARIPQNTTSVIICQDSYYISNSQLNKNERRLINYDHPSSFE*DLMREQLSDIK
KRKKIKVPIYDYKTEIRLDKTIDISDVDVIVFEGIYAIYDDVINQIADLKVFIETPKDECLIRRILRDVNERNRSFESVI
TQ*RSTVSPMYDQFVEPSKKNANVSVL*NEHNRVALHLINK*INNIH

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=206, Percent_Identity=33.9805825242718, Blast_Score=131, Evalue=5e-31,
Organism=Homo sapiens, GI13899253, Length=204, Percent_Identity=36.2745098039216, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI301129207, Length=207, Percent_Identity=34.2995169082126, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI57863312, Length=207, Percent_Identity=34.2995169082126, Blast_Score=121, Evalue=4e-28,
Organism=Homo sapiens, GI209863022, Length=149, Percent_Identity=34.2281879194631, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI87082034, Length=197, Percent_Identity=37.5634517766497, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17539894, Length=200, Percent_Identity=35.5, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17539892, Length=200, Percent_Identity=35.5, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71981181, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324339, Length=193, Percent_Identity=33.6787564766839, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24649624, Length=205, Percent_Identity=37.0731707317073, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221458995, Length=205, Percent_Identity=37.0731707317073, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573516, Length=204, Percent_Identity=31.8627450980392, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573514, Length=204, Percent_Identity=31.8627450980392, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28573512, Length=204, Percent_Identity=31.8627450980392, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45550449, Length=204, Percent_Identity=31.8627450980392, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 23286; Mature: 23286

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKSPILVLIAGASGSGKTTFANEIVARIPQNTTSVIICQDSYYISNSQLNKNERRLIN
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCEEEC
YDHPSSFEDLMREQLSDIKKRKKIKVPIYDYKTEIRLDKTIDISDVDVIVFEGIYAIYDD
CCCCCCHHHHHHHHHHHHHHHCEECCCEECCCEEEEECCEECCCCCHHHHHHHHHHHHHH
VINQIADLKVFIETPKDECLIRRILRDVNERNRSFESVITQRSTVSPMYDQFVEPSKKNA
HHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
NVSVLNEHNRVALHLINKINNIH
CEEEEECCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAKSPILVLIAGASGSGKTTFANEIVARIPQNTTSVIICQDSYYISNSQLNKNERRLIN
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCEEEC
YDHPSSFEDLMREQLSDIKKRKKIKVPIYDYKTEIRLDKTIDISDVDVIVFEGIYAIYDD
CCCCCCHHHHHHHHHHHHHHHCEECCCEECCCEEEEECCEECCCCCHHHHHHHHHHHHHH
VINQIADLKVFIETPKDECLIRRILRDVNERNRSFESVITQRSTVSPMYDQFVEPSKKNA
HHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
NVSVLNEHNRVALHLINKINNIH
CEEEEECCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA