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The map label for this gene is tkt [H]

Identifier: 209554596

GI number: 209554596

Start: 856288

End: 858252

Strand: Reverse

Name: tkt [H]

Synonym: UUR10_0690

Alternate gene names: 209554596

Gene position: 858252-856288 (Counterclockwise)

Preceding gene: 209554527

Following gene: 209554016

Centisome position: 98.14

GC content: 29.67

Gene sequence:

>1965_bases
ATGAATCGTTATGTTAACGCAATGCGTTCACTTGCTTTACAAGCTATTAATAAAGCAAATCAAGGGCATAGTGGAATGAG
TATTTCTGCTGCGCCCATTATTTATACTCTTTATAAAGGATTAATGACTATTTCTAAATCACATCCAAAATGATTTAATC
GTGATCGTTTAGTTTTATCAGCTGGGCATGGATCAATGGCATTATATCCTGTTTTTTATTTTTCATCATTATTAACACTT
GATGATATTAAAAACTTTCGTAATGACAATCATTTAACACCAGGTCATCCTGAAGTTTTATCAAATAATTATATTGATGC
ATCAACTGGTCCATTAGGTCAAGGTGTTGCTAATGCAGTTGGTATGGCAATTACTGAAAGTTATTTAAGAGCAGAATTTG
CCAGCCTTAAAGGTGTTGTTGATCATTATACATACTGCATTGTTGGTGATGGTGATTTACAAGAAGGGATTAGTTATGAA
GCAATGAGTATTGCTGGGAAACTTAAATTATCAAAACTAATTATTCTACATGATTCAAATGATTATCAATTAGATTCAGC
AGTTAGTGATGTAAATATTGAAGATTTAAAAATGCGTGTTGAATCAATGGGATGAAATTATTTAAAAACTGATAATAATC
CCGAAAATATTTTTAAAGCAATTGCTGAAGCTAAATGAAAGAAAAATGTTAAACCAACATTTATTGAAGTAAAAACAATT
ATTGGTGAAGGAACATCATTTGAAAATAGTAATGAAGCTCATGCTGCAGCAATATCTAAAGAAGAGTTAGAAAAATTTGG
TAAACGTTTTCACACAAAAACTAATAATTTTGAATTTCATCAAGAAATCTTTGACCATTTCTTTTTTAATGTTGTCGCTC
GTGGTGAAAGTGCATATAATCAATGACAACAATTAGTTGATCAATATATGCAAACAAATCCTGAACAAATGCAACGTTTA
TTAAATTACATTAATGGAAATTATGAAGATTTAAATAAAATGTTAGATGAAAACAAGATTGTTAATTTAAGTGATTCAAC
TCGTAGTTATTTAAAACAATACTTTGCTCAACTTAAAGATCTTAAATCAGCACTTGTTTTATCAGCTGATTTAGCAAAAT
CAACATTTACAAAAATTGGCGAAAACGCTTTTAATGATGATTATAAAAATCCATACATTAAATTTGGGATTCGTGAATTT
GCCATGGCTGGAGCTATGAATGGGATTAGTTTGCACCAAGGTGCTAAAGCAATTGGGGGAACTTTTTTAGCCTTCTCTGA
TTATATGAAACCTGCTATTCGTTTAACTGCTATTAGCAATTTAGCTAACTTATTTATTTTTAGTCATGATAGTTATGCTG
TTGGTGGAGATGGACCAACACATCAACCAGTTGATCAATTGCCAATGTTAAGAGCAATTCCTAATGTAGAAGTTATTCGC
CCTGCTGATCATTATGAAGTCAAACATGCTCTATCATATAGTTTTAAACAAAAACAAAAACCAATTTGTTTAGTTACTTC
ACGTCAAGCTATTAAACAAATCAATGAACAAAAACCACAAGATTTCACTAAAGGTGCATACATTATTAACTCGCCATTTT
CTTTTAGTGAAAATCCTGATTACACAATTATTGCTTCAGGTAGTGAAGTAAGTTTAGCAAATGATGCAGCTAAAGAAATT
TTTGAAAAACATCAATTAAAAGTTAAAGTTATTTCAGCTTTTAACTTAAATTTATTTTTACAACAAAAACCTGAAGTTAT
TAAAAATTTAGTAAGTTCAAAAAATGGTTTATTAGCGATTGAAGCATCGAGCGAAATGCTTTGATGAAAACTATCAGTTT
ATACTAATAAATTTATGCAGATTGCTGCTAATCAATTTGGGCGTAGCGCAGATGGTAATAAATTAATGCACGAATTTGGT
TTTAGTGTTGAAAACATTATCAATCAACTTTTAAATAAAAAATAA

Upstream 100 bases:

>100_bases
TGCAAATGAAGCAATTAATAAATTAGAAGAAATTTTAATTGAACAAAAATTAATTTAAATATATTAAATATCTTTATTTT
TTTAGTGGAGATTATAGAAT

Downstream 100 bases:

>100_bases
GGAAATATTTTTATGAATAAATATAGTATTTACGTTGATCACACTTTATTAAAACCTGATGCAAGTTTAGATGAAATTCA
CAATTTATGCGAAGAAGCTG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MNRYVNAMRSLALQAINKANQGHSGMSISAAPIIYTLYKGLMTISKSHPKWFNRDRLVLSAGHGSMALYPVFYFSSLLTL
DDIKNFRNDNHLTPGHPEVLSNNYIDASTGPLGQGVANAVGMAITESYLRAEFASLKGVVDHYTYCIVGDGDLQEGISYE
AMSIAGKLKLSKLIILHDSNDYQLDSAVSDVNIEDLKMRVESMGWNYLKTDNNPENIFKAIAEAKWKKNVKPTFIEVKTI
IGEGTSFENSNEAHAAAISKEELEKFGKRFHTKTNNFEFHQEIFDHFFFNVVARGESAYNQWQQLVDQYMQTNPEQMQRL
LNYINGNYEDLNKMLDENKIVNLSDSTRSYLKQYFAQLKDLKSALVLSADLAKSTFTKIGENAFNDDYKNPYIKFGIREF
AMAGAMNGISLHQGAKAIGGTFLAFSDYMKPAIRLTAISNLANLFIFSHDSYAVGGDGPTHQPVDQLPMLRAIPNVEVIR
PADHYEVKHALSYSFKQKQKPICLVTSRQAIKQINEQKPQDFTKGAYIINSPFSFSENPDYTIIASGSEVSLANDAAKEI
FEKHQLKVKVISAFNLNLFLQQKPEVIKNLVSSKNGLLAIEASSEMLWWKLSVYTNKFMQIAANQFGRSADGNKLMHEFG
FSVENIINQLLNKK

Sequences:

>Translated_654_residues
MNRYVNAMRSLALQAINKANQGHSGMSISAAPIIYTLYKGLMTISKSHPK*FNRDRLVLSAGHGSMALYPVFYFSSLLTL
DDIKNFRNDNHLTPGHPEVLSNNYIDASTGPLGQGVANAVGMAITESYLRAEFASLKGVVDHYTYCIVGDGDLQEGISYE
AMSIAGKLKLSKLIILHDSNDYQLDSAVSDVNIEDLKMRVESMG*NYLKTDNNPENIFKAIAEAK*KKNVKPTFIEVKTI
IGEGTSFENSNEAHAAAISKEELEKFGKRFHTKTNNFEFHQEIFDHFFFNVVARGESAYNQ*QQLVDQYMQTNPEQMQRL
LNYINGNYEDLNKMLDENKIVNLSDSTRSYLKQYFAQLKDLKSALVLSADLAKSTFTKIGENAFNDDYKNPYIKFGIREF
AMAGAMNGISLHQGAKAIGGTFLAFSDYMKPAIRLTAISNLANLFIFSHDSYAVGGDGPTHQPVDQLPMLRAIPNVEVIR
PADHYEVKHALSYSFKQKQKPICLVTSRQAIKQINEQKPQDFTKGAYIINSPFSFSENPDYTIIASGSEVSLANDAAKEI
FEKHQLKVKVISAFNLNLFLQQKPEVIKNLVSSKNGLLAIEASSEML**KLSVYTNKFMQIAANQFGRSADGNKLMHEFG
FSVENIINQLLNKK
>Mature_654_residues
MNRYVNAMRSLALQAINKANQGHSGMSISAAPIIYTLYKGLMTISKSHPK*FNRDRLVLSAGHGSMALYPVFYFSSLLTL
DDIKNFRNDNHLTPGHPEVLSNNYIDASTGPLGQGVANAVGMAITESYLRAEFASLKGVVDHYTYCIVGDGDLQEGISYE
AMSIAGKLKLSKLIILHDSNDYQLDSAVSDVNIEDLKMRVESMG*NYLKTDNNPENIFKAIAEAK*KKNVKPTFIEVKTI
IGEGTSFENSNEAHAAAISKEELEKFGKRFHTKTNNFEFHQEIFDHFFFNVVARGESAYNQ*QQLVDQYMQTNPEQMQRL
LNYINGNYEDLNKMLDENKIVNLSDSTRSYLKQYFAQLKDLKSALVLSADLAKSTFTKIGENAFNDDYKNPYIKFGIREF
AMAGAMNGISLHQGAKAIGGTFLAFSDYMKPAIRLTAISNLANLFIFSHDSYAVGGDGPTHQPVDQLPMLRAIPNVEVIR
PADHYEVKHALSYSFKQKQKPICLVTSRQAIKQINEQKPQDFTKGAYIINSPFSFSENPDYTIIASGSEVSLANDAAKEI
FEKHQLKVKVISAFNLNLFLQQKPEVIKNLVSSKNGLLAIEASSEML**KLSVYTNKFMQIAANQFGRSADGNKLMHEFG
FSVENIINQLLNKK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=651, Percent_Identity=26.1136712749616, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI4507521, Length=651, Percent_Identity=26.1136712749616, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI133778974, Length=581, Percent_Identity=24.7848537005164, Blast_Score=126, Evalue=8e-29,
Organism=Homo sapiens, GI225637459, Length=563, Percent_Identity=23.6234458259325, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI225637463, Length=563, Percent_Identity=23.6234458259325, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI225637461, Length=563, Percent_Identity=23.6234458259325, Blast_Score=109, Evalue=1e-23,
Organism=Escherichia coli, GI48994911, Length=663, Percent_Identity=34.0874811463047, Blast_Score=353, Evalue=2e-98,
Organism=Escherichia coli, GI1788808, Length=661, Percent_Identity=32.0726172465961, Blast_Score=323, Evalue=2e-89,
Organism=Caenorhabditis elegans, GI17539652, Length=576, Percent_Identity=25.5208333333333, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6325331, Length=660, Percent_Identity=34.6969696969697, Blast_Score=347, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6319593, Length=660, Percent_Identity=33.1818181818182, Blast_Score=339, Evalue=8e-94,
Organism=Drosophila melanogaster, GI45551847, Length=581, Percent_Identity=26.3339070567986, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI45550715, Length=581, Percent_Identity=26.3339070567986, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24666278, Length=580, Percent_Identity=24.6551724137931, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24645119, Length=541, Percent_Identity=26.8022181146026, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72309; Mature: 72309

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRYVNAMRSLALQAINKANQGHSGMSISAAPIIYTLYKGLMTISKSHPKFNRDRLVLSA
CCHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
GHGSMALYPVFYFSSLLTLDDIKNFRNDNHLTPGHPEVLSNNYIDASTGPLGQGVANAVG
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHH
MAITESYLRAEFASLKGVVDHYTYCIVGDGDLQEGISYEAMSIAGKLKLSKLIILHDSND
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHCCCHHHHHHHHHEEEEEEEEEECCCC
YQLDSAVSDVNIEDLKMRVESMGNYLKTDNNPENIFKAIAEAKKKNVKPTFIEVKTIIGE
CCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHCC
GTSFENSNEAHAAAISKEELEKFGKRFHTKTNNFEFHQEIFDHFFFNVVARGESAYNQQQ
CCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCHHH
LVDQYMQTNPEQMQRLLNYINGNYEDLNKMLDENKIVNLSDSTRSYLKQYFAQLKDLKSA
HHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHH
LVLSADLAKSTFTKIGENAFNDDYKNPYIKFGIREFAMAGAMNGISLHQGAKAIGGTFLA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHCCCHHHCCHHHH
FSDYMKPAIRLTAISNLANLFIFSHDSYAVGGDGPTHQPVDQLPMLRAIPNVEVIRPADH
HHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCCCCHHHCCHHHHCCCCEEECCCHH
YEVKHALSYSFKQKQKPICLVTSRQAIKQINEQKPQDFTKGAYIINSPFSFSENPDYTII
HHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEE
ASGSEVSLANDAAKEIFEKHQLKVKVISAFNLNLFLQQKPEVIKNLVSSKNGLLAIEASS
ECCCCEEHHHHHHHHHHHHHCCEEEEEEEECCEEEECCCHHHHHHHHCCCCCEEEEECCC
EMLKLSVYTNKFMQIAANQFGRSADGNKLMHEFGFSVENIINQLLNKK
CEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNRYVNAMRSLALQAINKANQGHSGMSISAAPIIYTLYKGLMTISKSHPKFNRDRLVLSA
CCHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEE
GHGSMALYPVFYFSSLLTLDDIKNFRNDNHLTPGHPEVLSNNYIDASTGPLGQGVANAVG
CCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHH
MAITESYLRAEFASLKGVVDHYTYCIVGDGDLQEGISYEAMSIAGKLKLSKLIILHDSND
HHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHCCCHHHHHHHHHEEEEEEEEEECCCC
YQLDSAVSDVNIEDLKMRVESMGNYLKTDNNPENIFKAIAEAKKKNVKPTFIEVKTIIGE
CCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHCC
GTSFENSNEAHAAAISKEELEKFGKRFHTKTNNFEFHQEIFDHFFFNVVARGESAYNQQQ
CCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCHHH
LVDQYMQTNPEQMQRLLNYINGNYEDLNKMLDENKIVNLSDSTRSYLKQYFAQLKDLKSA
HHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHH
LVLSADLAKSTFTKIGENAFNDDYKNPYIKFGIREFAMAGAMNGISLHQGAKAIGGTFLA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHCCCHHHCCHHHH
FSDYMKPAIRLTAISNLANLFIFSHDSYAVGGDGPTHQPVDQLPMLRAIPNVEVIRPADH
HHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCCCCHHHCCHHHHCCCCEEECCCHH
YEVKHALSYSFKQKQKPICLVTSRQAIKQINEQKPQDFTKGAYIINSPFSFSENPDYTII
HHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEE
ASGSEVSLANDAAKEIFEKHQLKVKVISAFNLNLFLQQKPEVIKNLVSSKNGLLAIEASS
ECCCCEEHHHHHHHHHHHHHCCEEEEEEEECCEEEECCCHHHHHHHHCCCCCEEEEECCC
EMLKLSVYTNKFMQIAANQFGRSADGNKLMHEFGFSVENIINQLLNKK
CEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633; 11271496 [H]