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The map label for this gene is cdd [H]

Identifier: 209554522

GI number: 209554522

Start: 743640

End: 744035

Strand: Reverse

Name: cdd [H]

Synonym: UUR10_0622

Alternate gene names: 209554522

Gene position: 744035-743640 (Counterclockwise)

Preceding gene: 209554182

Following gene: 209554256

Centisome position: 85.08

GC content: 30.56

Gene sequence:

>396_bases
ATGAAATATAATGATATTTATAAAGGATTAATAGAACTATTAAAGAAAAGTTATAGTCCTTATTCAAACTATCCAGTAGC
AGCTTATGTTGATACTGATATCGGACTTATTCCTGGTGTGAATGTGGAAAATGGATCATTAGGATTAACTTCTTGTGCTG
AAAGAAATGCGATTTTTAATGCAATTACAAATGGGGCAAAAGTATTTAAAACAGTTTATGTAATCACAAAAAATAATGGC
GATATTGGCAGTCCTTGTGGCGCATGTCGTCAAGTAGTTTCTGAGTTTTTAAAAAAAGATGCAAAAGTTGTTGTTTTTAA
TAACGATGGAACTTATAAGGAGTATAGTGTCGAACAATTATTACCATTTGGATGAGATCCAAATGTATCTCTATAA

Upstream 100 bases:

>100_bases
TGGTTTTTTCTTATTTTTGCTTTTTATTAAAGGTTTAACCTTTTTTCAAAATGTTATAATATAGTGTTAAATGCTTATAA
TATTTGGAGTTATTAAAAAT

Downstream 100 bases:

>100_bases
TTATTTACAATAAGAAGGGAGATAAAAATTATGGAAAATACAAACAAACTTTTTAATTGTTGATTAAATTCACCAAAAAT
TTCTCAAACAATTAAAGAAG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKYNDIYKGLIELLKKSYSPYSNYPVAAYVDTDIGLIPGVNVENGSLGLTSCAERNAIFNAITNGAKVFKTVYVITKNNG
DIGSPCGACRQVVSEFLKKDAKVVVFNNDGTYKEYSVEQLLPFGWDPNVSL

Sequences:

>Translated_131_residues
MKYNDIYKGLIELLKKSYSPYSNYPVAAYVDTDIGLIPGVNVENGSLGLTSCAERNAIFNAITNGAKVFKTVYVITKNNG
DIGSPCGACRQVVSEFLKKDAKVVVFNNDGTYKEYSVEQLLPFG*DPNVSL
>Mature_131_residues
MKYNDIYKGLIELLKKSYSPYSNYPVAAYVDTDIGLIPGVNVENGSLGLTSCAERNAIFNAITNGAKVFKTVYVITKNNG
DIGSPCGACRQVVSEFLKKDAKVVVFNNDGTYKEYSVEQLLPFG*DPNVSL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=112, Percent_Identity=42.8571428571429, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=113, Percent_Identity=41.5929203539823, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551074, Length=113, Percent_Identity=40.7079646017699, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323274, Length=135, Percent_Identity=35.5555555555556, Blast_Score=73, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582741, Length=95, Percent_Identity=38.9473684210526, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920920, Length=126, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14167; Mature: 14167

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYNDIYKGLIELLKKSYSPYSNYPVAAYVDTDIGLIPGVNVENGSLGLTSCAERNAIFN
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AITNGAKVFKTVYVITKNNGDIGSPCGACRQVVSEFLKKDAKVVVFNNDGTYKEYSVEQL
HHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
LPFGDPNVSL
CCCCCCCCCC
>Mature Secondary Structure
MKYNDIYKGLIELLKKSYSPYSNYPVAAYVDTDIGLIPGVNVENGSLGLTSCAERNAIFN
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AITNGAKVFKTVYVITKNNGDIGSPCGACRQVVSEFLKKDAKVVVFNNDGTYKEYSVEQL
HHHCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
LPFGDPNVSL
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349569 [H]