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The map label for this gene is hmuU [H]

Identifier: 209554509

GI number: 209554509

Start: 92555

End: 93625

Strand: Reverse

Name: hmuU [H]

Synonym: UUR10_0076

Alternate gene names: 209554509

Gene position: 93625-92555 (Counterclockwise)

Preceding gene: 209554075

Following gene: 209554582

Centisome position: 10.71

GC content: 27.17

Gene sequence:

>1071_bases
ATGAAAATTAATTACAAAACAAAACTCAAACAACATCATTTTTATTTAATTAAAAACCTTAATTATAAACAATTTGCAAT
TATTAAAATGGCAGGGCTAATTGCTATTGCCCTTTGTTTTATTTTTTTGACATTAGCAATTTATTATGATACTACTAATG
GGTTTGATGTATCAATTAATCAATTTAATTTTAATATTCGTGGTCCCAAAACGTTAATGGCATTTTTCTCTGGAGGCGCT
ATTGCTGTAGCTGGACTATTATTACAAAAAGTTACACGTAATCATTTAGCAGACACTTCTGTTTTAGGAATTGGATCATT
AAATATTATTTTAATGACTTTTTATTTTATTCTTATAAAAGATAAAACAAGCAGTTATTTAAATCCTGAAATGCGTATCT
TACCATTAATTATGTTTTTATCATCAATTCTTGGAACAAGCATTGTTTATACTCTATCAAAACTAGGAAAGGCAAATAAT
GAAAAATTTATCATTATAGGAATCGCCTTAAACTTCTTATTTGAAGCAGTTTCTGTAGTTTTGATTAATCCTGCTAACAA
TTCGTTATTTTCAAATCAAGATAAGAATTTAATGATTGCTTTTGAAAACATTAAAAACTACACTTTAGGAATAATTCCTA
ATTCTCAATACATTGACTTATCATTAGTAATTTCATGTTCAATTTTAATTACATTAACATTAATTCCAATTTGATTTTTG
CGTAAAAAAATTGATTTATATGAAACAAGCGCTGCTTTAGCATCAACAACAGGAATTAATGTTGAACGTTTAAAAATTAG
TATTTATTTCCTTGTGGCCTTATTGGCAGGTTTAGAAATTGTTTTAGTTGGCTATGTCGCTTTATTAGGTGTTATTGGAG
CAAGTGTTGCTCGCCAATTATTTGGCAACAAAACAGGAATTACAATGTTTGCTGCTTTTTTAATTGGAGCTATTTTAGTT
TGTTTCGCCTTATTAATTTCAGTCAATTTTAATACGCAAGTTCCAGTTGGCTTTTTATCAACAACAATTATCACGCCTTA
TTTTATGTATTTAATTGTGAGAGGTAAATAA

Upstream 100 bases:

>100_bases
ATCCGCAAGTAATTAAACAAAATGAACATTTATTAAGAGAAGCCAATAATTGAGGTTCATATTGAGATACATTTGTTAAC
TCAAAATAAAAAGAGGACTA

Downstream 100 bases:

>100_bases
AAATATGTTTAAAATTTTCAGTAAATATTTTTGTAATCATCAATTAGATCGAGATCGAATTATTAAAGAAAGCAATGATT
ATGCTTTAGTTGTTGATAAT

Product: hemin transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKINYKTKLKQHHFYLIKNLNYKQFAIIKMAGLIAIALCFIFLTLAIYYDTTNGFDVSINQFNFNIRGPKTLMAFFSGGA
IAVAGLLLQKVTRNHLADTSVLGIGSLNIILMTFYFILIKDKTSSYLNPEMRILPLIMFLSSILGTSIVYTLSKLGKANN
EKFIIIGIALNFLFEAVSVVLINPANNSLFSNQDKNLMIAFENIKNYTLGIIPNSQYIDLSLVISCSILITLTLIPIWFL
RKKIDLYETSAALASTTGINVERLKISIYFLVALLAGLEIVLVGYVALLGVIGASVARQLFGNKTGITMFAAFLIGAILV
CFALLISVNFNTQVPVGFLSTTIITPYFMYLIVRGK

Sequences:

>Translated_356_residues
MKINYKTKLKQHHFYLIKNLNYKQFAIIKMAGLIAIALCFIFLTLAIYYDTTNGFDVSINQFNFNIRGPKTLMAFFSGGA
IAVAGLLLQKVTRNHLADTSVLGIGSLNIILMTFYFILIKDKTSSYLNPEMRILPLIMFLSSILGTSIVYTLSKLGKANN
EKFIIIGIALNFLFEAVSVVLINPANNSLFSNQDKNLMIAFENIKNYTLGIIPNSQYIDLSLVISCSILITLTLIPI*FL
RKKIDLYETSAALASTTGINVERLKISIYFLVALLAGLEIVLVGYVALLGVIGASVARQLFGNKTGITMFAAFLIGAILV
CFALLISVNFNTQVPVGFLSTTIITPYFMYLIVRGK
>Mature_356_residues
MKINYKTKLKQHHFYLIKNLNYKQFAIIKMAGLIAIALCFIFLTLAIYYDTTNGFDVSINQFNFNIRGPKTLMAFFSGGA
IAVAGLLLQKVTRNHLADTSVLGIGSLNIILMTFYFILIKDKTSSYLNPEMRILPLIMFLSSILGTSIVYTLSKLGKANN
EKFIIIGIALNFLFEAVSVVLINPANNSLFSNQDKNLMIAFENIKNYTLGIIPNSQYIDLSLVISCSILITLTLIPI*FL
RKKIDLYETSAALASTTGINVERLKISIYFLVALLAGLEIVLVGYVALLGVIGASVARQLFGNKTGITMFAAFLIGAILV
CFALLISVNFNTQVPVGFLSTTIITPYFMYLIVRGK

Specific function: Part of the binding-protein-dependent transport system for hemin; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=291, Percent_Identity=25.4295532646048, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786347, Length=290, Percent_Identity=24.4827586206897, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 39226; Mature: 39226

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINYKTKLKQHHFYLIKNLNYKQFAIIKMAGLIAIALCFIFLTLAIYYDTTNGFDVSIN
CCCCCHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEE
QFNFNIRGPKTLMAFFSGGAIAVAGLLLQKVTRNHLADTSVLGIGSLNIILMTFYFILIK
EEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHEE
DKTSSYLNPEMRILPLIMFLSSILGTSIVYTLSKLGKANNEKFIIIGIALNFLFEAVSVV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHEE
LINPANNSLFSNQDKNLMIAFENIKNYTLGIIPNSQYIDLSLVISCSILITLTLIPIFLR
EECCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
KKIDLYETSAALASTTGINVERLKISIYFLVALLAGLEIVLVGYVALLGVIGASVARQLF
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNKTGITMFAAFLIGAILVCFALLISVNFNTQVPVGFLSTTIITPYFMYLIVRGK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKINYKTKLKQHHFYLIKNLNYKQFAIIKMAGLIAIALCFIFLTLAIYYDTTNGFDVSIN
CCCCCHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEE
QFNFNIRGPKTLMAFFSGGAIAVAGLLLQKVTRNHLADTSVLGIGSLNIILMTFYFILIK
EEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHEE
DKTSSYLNPEMRILPLIMFLSSILGTSIVYTLSKLGKANNEKFIIIGIALNFLFEAVSVV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHEE
LINPANNSLFSNQDKNLMIAFENIKNYTLGIIPNSQYIDLSLVISCSILITLTLIPIFLR
EECCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHH
KKIDLYETSAALASTTGINVERLKISIYFLVALLAGLEIVLVGYVALLGVIGASVARQLF
HHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNKTGITMFAAFLIGAILVCFALLISVNFNTQVPVGFLSTTIITPYFMYLIVRGK
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]