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The map label for this gene is hemN [H]

Identifier: 209554476

GI number: 209554476

Start: 296819

End: 297883

Strand: Reverse

Name: hemN [H]

Synonym: UUR10_0270

Alternate gene names: 209554476

Gene position: 297883-296819 (Counterclockwise)

Preceding gene: 209554455

Following gene: 209554004

Centisome position: 34.06

GC content: 22.25

Gene sequence:

>1065_bases
ATGATTTTTAGTCAAAATACTAAACATTTATATATTCACATTCCATTTTGCAACCATATTTGCACATATTCTGATTTTAA
GCGAATTTTAAAAACTGTACAATCAAAAGATATTTTTAAAGATTTTTTAAAAGATGTGCAAATGCGAATTAAAAATTTTA
AAACAAAGCAATTTGAAACAATTTATTTAGGTGGTGGTGTACCTAATTGTTTGAGTAATTGTGAACTCAAACAATTATTG
CAAACCATTTTTCCTTATGTAAGTAATAATTGTGAATATACTATTGAATGTAATCCTGAACTCATAAACCAAACTCAAAT
TAATCTTTTTAAAAAATATAAAATCAATCGTATTAGTCTTAACGCACAATCATTAAACAATAATATCTTAAAGAAAATGA
ATTATATTCATACTAATCAAGATATTAAAAATGCGATTGATTTATTCTATAAAAACAAAATATTCAATATTTCATGCGAT
TTCTTATATTGTTTAACAATGTTAACATTAAAGGATTTAGATGATATTTTTGATTTTATTGTTCAGAATAAAATTAATCA
TGTTTCTTTTTATGGTTTAGAAATTAAAGATGAATCAATTTTAAAAAAACTTAACATTAGTATTAATGAAGATCAAGATG
CTGAACAAATGAGTTATGTAAATAATAAATTTGCATCCTTAAATTTTAAACATTATGAAGTATCTAATTGAGTAAGTGAT
TTAAAATATGTTGCAAAACATAATTTAGCTTATTGGCAAACCAAAGATTGAGCTGCAATAGGATGAGGCGCTCATGGTTT
TGAAAATAACATTGAATATTTCTTTGATGCTCCAGTCCAAAAGCCTGTATTAATTAAAAAAATGTTGACAAAGTATGATA
TTTATCAACAAATTTTAATGATGGGTTTAAGATTAAAAGAAGGTTTAAATCTTAATGAAAAAATTAATAATGATGCTTAT
CTATATTTTAAAGATAAGCTTAAATATATTAGCATCAATAAAAAAAATCATCTAGTTGTTGATGATTTAAATTTATTAAA
TTCAAGTATTTTAGACATTTTTTAA

Upstream 100 bases:

>100_bases
TTTATCAATTTTTTTAATTTTATTGACTTGTGGTGCCATTATTTTATTAGTTTTTGTGATCACTGAATTATTTAGATTAA
GTGCATAAAAAATTAATCTT

Downstream 100 bases:

>100_bases
TATAAATTAATTAGATTTAATAATAATTGTGTTGTGCTTGATGATGAAGAATTAGTTAAGCCAAAATATAAACCTAATAT
TAAAACTAATAATATAATGA

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MIFSQNTKHLYIHIPFCNHICTYSDFKRILKTVQSKDIFKDFLKDVQMRIKNFKTKQFETIYLGGGVPNCLSNCELKQLL
QTIFPYVSNNCEYTIECNPELINQTQINLFKKYKINRISLNAQSLNNNILKKMNYIHTNQDIKNAIDLFYKNKIFNISCD
FLYCLTMLTLKDLDDIFDFIVQNKINHVSFYGLEIKDESILKKLNISINEDQDAEQMSYVNNKFASLNFKHYEVSNWVSD
LKYVAKHNLAYWQTKDWAAIGWGAHGFENNIEYFFDAPVQKPVLIKKMLTKYDIYQQILMMGLRLKEGLNLNEKINNDAY
LYFKDKLKYISINKKNHLVVDDLNLLNSSILDIF

Sequences:

>Translated_354_residues
MIFSQNTKHLYIHIPFCNHICTYSDFKRILKTVQSKDIFKDFLKDVQMRIKNFKTKQFETIYLGGGVPNCLSNCELKQLL
QTIFPYVSNNCEYTIECNPELINQTQINLFKKYKINRISLNAQSLNNNILKKMNYIHTNQDIKNAIDLFYKNKIFNISCD
FLYCLTMLTLKDLDDIFDFIVQNKINHVSFYGLEIKDESILKKLNISINEDQDAEQMSYVNNKFASLNFKHYEVSN*VSD
LKYVAKHNLAYWQTKD*AAIG*GAHGFENNIEYFFDAPVQKPVLIKKMLTKYDIYQQILMMGLRLKEGLNLNEKINNDAY
LYFKDKLKYISINKKNHLVVDDLNLLNSSILDIF
>Mature_354_residues
MIFSQNTKHLYIHIPFCNHICTYSDFKRILKTVQSKDIFKDFLKDVQMRIKNFKTKQFETIYLGGGVPNCLSNCELKQLL
QTIFPYVSNNCEYTIECNPELINQTQINLFKKYKINRISLNAQSLNNNILKKMNYIHTNQDIKNAIDLFYKNKIFNISCD
FLYCLTMLTLKDLDDIFDFIVQNKINHVSFYGLEIKDESILKKLNISINEDQDAEQMSYVNNKFASLNFKHYEVSN*VSD
LKYVAKHNLAYWQTKD*AAIG*GAHGFENNIEYFFDAPVQKPVLIKKMLTKYDIYQQILMMGLRLKEGLNLNEKINNDAY
LYFKDKLKYISINKKNHLVVDDLNLLNSSILDIF

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=265, Percent_Identity=23.0188679245283, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1789325, Length=264, Percent_Identity=29.5454545454545, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 41215; Mature: 41215

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQNTKHLYIHIPFCNHICTYSDFKRILKTVQSKDIFKDFLKDVQMRIKNFKTKQFET
CCCCCCCCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IYLGGGVPNCLSNCELKQLLQTIFPYVSNNCEYTIECNPELINQTQINLFKKYKINRISL
EEECCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHCHHHHHHHHHEEEEEEEE
NAQSLNNNILKKMNYIHTNQDIKNAIDLFYKNKIFNISCDFLYCLTMLTLKDLDDIFDFI
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
VQNKINHVSFYGLEIKDESILKKLNISINEDQDAEQMSYVNNKFASLNFKHYEVSNVSDL
HHCCCCEEEEEEEEECHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHH
KYVAKHNLAYWQTKDAAIGGAHGFENNIEYFFDAPVQKPVLIKKMLTKYDIYQQILMMGL
HHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RLKEGLNLNEKINNDAYLYFKDKLKYISINKKNHLVVDDLNLLNSSILDIF
HHHCCCCCCCCCCCCEEEEEECCEEEEEECCCCCEEEECHHHHHHHHHHCC
>Mature Secondary Structure
MIFSQNTKHLYIHIPFCNHICTYSDFKRILKTVQSKDIFKDFLKDVQMRIKNFKTKQFET
CCCCCCCCEEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
IYLGGGVPNCLSNCELKQLLQTIFPYVSNNCEYTIECNPELINQTQINLFKKYKINRISL
EEECCCCCHHHCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHCHHHHHHHHHEEEEEEEE
NAQSLNNNILKKMNYIHTNQDIKNAIDLFYKNKIFNISCDFLYCLTMLTLKDLDDIFDFI
EHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
VQNKINHVSFYGLEIKDESILKKLNISINEDQDAEQMSYVNNKFASLNFKHYEVSNVSDL
HHCCCCEEEEEEEEECHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHH
KYVAKHNLAYWQTKDAAIGGAHGFENNIEYFFDAPVQKPVLIKKMLTKYDIYQQILMMGL
HHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
RLKEGLNLNEKINNDAYLYFKDKLKYISINKKNHLVVDDLNLLNSSILDIF
HHHCCCCCCCCCCCCEEEEEECCEEEEEECCCCCEEEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]