Click here to switch to the map view.

The map label for this gene is gpo [H]

Identifier: 209554233

GI number: 209554233

Start: 314528

End: 315001

Strand: Reverse

Name: gpo [H]

Synonym: UUR10_0288

Alternate gene names: 209554233

Gene position: 315001-314528 (Counterclockwise)

Preceding gene: 209554539

Following gene: 209554031

Centisome position: 36.02

GC content: 24.89

Gene sequence:

>474_bases
ATGAAATTAAGTGATTATCCAGTATTAGATATCGACAAAAAACTATTTGATTGATCAAAAATTAAAAACAAACTAGTCTT
AATTGTTAACGTAGCAAGTAAATGTGGGTATGCTAAACAATATGAACAATTAGAGTATTTATACCAAAAATATAAAAACA
AAGGTTTTGTTATCATCGCTTTTCCTTGTCGTCAATTTATGTTTCAAGAGTTTGATGATAATAATAAAATAAAAGAATTT
TGTACAACAAAATATAATGTAAGTTTTCCAATAATGTATTTAACCAATGTTATTGGTTCAAACATTTCTCCTTTGTATAA
ACAATTAATTACTGAATATCCATGAAGTCCAAAAGCAAAAGCAGTGAAATGAAATTTTGAAAAATTTTTCGTTAAAAACG
ATGAGGTTATTGGTCGTTTTGAATCAAAATGCGAACCAAATGATTTAGAAGAATTCATCAAAAATAACTTATAA

Upstream 100 bases:

>100_bases
TAATATGTAATATTATTGGTTTTAATATCTAAAAATCTAATTAATAATTTAGAGTATAATTTTAATGCTTTAACATTAAA
AAAGCATAGAGAGGTTGAAT

Downstream 100 bases:

>100_bases
AAAATTAATGTCTACACGAACGCTTAAAATTTCTAAAGTTAAATTAAAAATTGTTGATGCTTTGTTTAATTTACTAAAAA
CTAATGCTTTTGATAAGATT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKLSDYPVLDIDKKLFDWSKIKNKLVLIVNVASKCGYAKQYEQLEYLYQKYKNKGFVIIAFPCRQFMFQEFDDNNKIKEF
CTTKYNVSFPIMYLTNVIGSNISPLYKQLITEYPWSPKAKAVKWNFEKFFVKNDEVIGRFESKCEPNDLEEFIKNNL

Sequences:

>Translated_157_residues
MKLSDYPVLDIDKKLFD*SKIKNKLVLIVNVASKCGYAKQYEQLEYLYQKYKNKGFVIIAFPCRQFMFQEFDDNNKIKEF
CTTKYNVSFPIMYLTNVIGSNISPLYKQLITEYP*SPKAKAVK*NFEKFFVKNDEVIGRFESKCEPNDLEEFIKNNL
>Mature_157_residues
MKLSDYPVLDIDKKLFD*SKIKNKLVLIVNVASKCGYAKQYEQLEYLYQKYKNKGFVIIAFPCRQFMFQEFDDNNKIKEF
CTTKYNVSFPIMYLTNVIGSNISPLYKQLITEYP*SPKAKAVK*NFEKFFVKNDEVIGRFESKCEPNDLEEFIKNNL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=137, Percent_Identity=34.3065693430657, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=33.5483870967742, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=34, Blast_Score=71, Evalue=4e-13,
Organism=Homo sapiens, GI192455698, Length=126, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1788003, Length=161, Percent_Identity=37.888198757764, Blast_Score=105, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71993584, Length=146, Percent_Identity=41.7808219178082, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506887, Length=140, Percent_Identity=39.2857142857143, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17535473, Length=140, Percent_Identity=37.8571428571429, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193210707, Length=154, Percent_Identity=33.7662337662338, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=139, Percent_Identity=47.4820143884892, Blast_Score=118, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6322228, Length=156, Percent_Identity=44.8717948717949, Blast_Score=115, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322826, Length=130, Percent_Identity=46.9230769230769, Blast_Score=111, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24656767, Length=138, Percent_Identity=36.9565217391304, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24656777, Length=138, Percent_Identity=36.9565217391304, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24656772, Length=138, Percent_Identity=36.9565217391304, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18112; Mature: 18112

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSDYPVLDIDKKLFDSKIKNKLVLIVNVASKCGYAKQYEQLEYLYQKYKNKGFVIIAF
CCCCCCCCCCHHHHHHHHHHCCCEEEEEEECHHCCCHHHHHHHHHHHHHHCCCCEEEEEE
PCRQFMFQEFDDNNKIKEFCTTKYNVSFPIMYLTNVIGSNISPLYKQLITEYPSPKAKAV
HHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
KNFEKFFVKNDEVIGRFESKCEPNDLEEFIKNNL
HHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MKLSDYPVLDIDKKLFDSKIKNKLVLIVNVASKCGYAKQYEQLEYLYQKYKNKGFVIIAF
CCCCCCCCCCHHHHHHHHHHCCCEEEEEEECHHCCCHHHHHHHHHHHHHHCCCCEEEEEE
PCRQFMFQEFDDNNKIKEFCTTKYNVSFPIMYLTNVIGSNISPLYKQLITEYPSPKAKAV
HHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHH
KNFEKFFVKNDEVIGRFESKCEPNDLEEFIKNNL
HHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]