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The map label for this gene is trxB [H]

Identifier: 209554196

GI number: 209554196

Start: 98153

End: 99082

Strand: Reverse

Name: trxB [H]

Synonym: UUR10_0080

Alternate gene names: 209554196

Gene position: 99082-98153 (Counterclockwise)

Preceding gene: 209554281

Following gene: 209554066

Centisome position: 11.33

GC content: 29.03

Gene sequence:

>930_bases
ATGAATCAACAAATTTATGATTTAGTGATTATTGGTGCAGGTCCAGCAGGATTAGCTGCTGCTGTTTATGCTAAACGTTC
AGGTTTAAATGTCATTATTGTTGAAAAGCAATTTCCAGGTGGCAAAGTAGCACTAACAGCAAATGTGGAAAACTATTTAG
GAATTAATAGTATTTCAGGACCTGAATTAGCTTATAAAATGTACGAACAAGTTTTAAATTTAGATATTCTTGTAATTTAT
GAATTAGCTGATGAAATCACTTTAAAAGAAAAATATAAAGAAGTTAAATTAGCTACACAAACACTAATTGCTAAAACTGT
AATTATTGCAACAGGAACAGAAAATAGACGTTTAAACATTCCTGGTGAATTAACATTTGAAAACAAAGGGATTAGTTATT
GTGCAATTTGTGATGGACCACTTTATAAAAATAAAGTTGTTTCTGTTATAGGTTCTGGTAATTCAGCAGTTGAAGAAGCA
ATTTATTTAGCAACCATTGCTAAAGAAGTTCATTTAATTGCTAATAAACCAGAATTTAAAGCTGAACGACAAATGGTTGA
AATTGTTAAGAACACTTCTAATATAAAGATTCATTACAATAAGCAAACATTCGAATTTTTTGGCGAAGAGTTTTTGCAAG
GTTTAAGATTTAAAGATTTAGTTACCAATGAAATAACAACATTAAATGTTGAAGCCAATTTCACTTTTATTGGTTTATTA
CCATCAAGAATTAATGCAAGTAACTTAAATATTTTTAATGAAACAAACGGTTTTATTACAACTAATAAGAATATGGAAAC
CAATGTTCATGGAATTTTTGCAGCTGGAGATATTGTTGATAAAAGTGTTCGACAAATCGCTACAGCTATAAATGATGGAG
TAATTGCTGCGCTTTATGCAAAAGAGTACATTACAAGAAATAATTGATAA

Upstream 100 bases:

>100_bases
TATTTTACAAAAAGAAACAACAAGCTCACAAGTTTGGTCAATTAAGAAATCCTGAGGAATTTTTATATTATTGCCACAAA
TAAAAGAAAGTAGGTGTTAA

Downstream 100 bases:

>100_bases
AGATCTTAACAAATTTACTTTTAGTGAATTTGTTAAAGAAGATATTTATACGAATACTGATTATTCTTCAACAGATTACA
AAGTTATTTTATATTCTTTT

Product: thioredoxin-disulfide reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNQQIYDLVIIGAGPAGLAAAVYAKRSGLNVIIVEKQFPGGKVALTANVENYLGINSISGPELAYKMYEQVLNLDILVIY
ELADEITLKEKYKEVKLATQTLIAKTVIIATGTENRRLNIPGELTFENKGISYCAICDGPLYKNKVVSVIGSGNSAVEEA
IYLATIAKEVHLIANKPEFKAERQMVEIVKNTSNIKIHYNKQTFEFFGEEFLQGLRFKDLVTNEITTLNVEANFTFIGLL
PSRINASNLNIFNETNGFITTNKNMETNVHGIFAAGDIVDKSVRQIATAINDGVIAALYAKEYITRNNW

Sequences:

>Translated_309_residues
MNQQIYDLVIIGAGPAGLAAAVYAKRSGLNVIIVEKQFPGGKVALTANVENYLGINSISGPELAYKMYEQVLNLDILVIY
ELADEITLKEKYKEVKLATQTLIAKTVIIATGTENRRLNIPGELTFENKGISYCAICDGPLYKNKVVSVIGSGNSAVEEA
IYLATIAKEVHLIANKPEFKAERQMVEIVKNTSNIKIHYNKQTFEFFGEEFLQGLRFKDLVTNEITTLNVEANFTFIGLL
PSRINASNLNIFNETNGFITTNKNMETNVHGIFAAGDIVDKSVRQIATAINDGVIAALYAKEYITRNN*
>Mature_309_residues
MNQQIYDLVIIGAGPAGLAAAVYAKRSGLNVIIVEKQFPGGKVALTANVENYLGINSISGPELAYKMYEQVLNLDILVIY
ELADEITLKEKYKEVKLATQTLIAKTVIIATGTENRRLNIPGELTFENKGISYCAICDGPLYKNKVVSVIGSGNSAVEEA
IYLATIAKEVHLIANKPEFKAERQMVEIVKNTSNIKIHYNKQTFEFFGEEFLQGLRFKDLVTNEITTLNVEANFTFIGLL
PSRINASNLNIFNETNGFITTNKNMETNVHGIFAAGDIVDKSVRQIATAINDGVIAALYAKEYITRNN*

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=35.7827476038339, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=36.5384615384615, Blast_Score=168, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=34.185303514377, Blast_Score=167, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=33.1210191082803, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33947; Mature: 33947

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQIYDLVIIGAGPAGLAAAVYAKRSGLNVIIVEKQFPGGKVALTANVENYLGINSISG
CCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECHHHHCCCCCCCC
PELAYKMYEQVLNLDILVIYELADEITLKEKYKEVKLATQTLIAKTVIIATGTENRRLNI
HHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEC
PGELTFENKGISYCAICDGPLYKNKVVSVIGSGNSAVEEAIYLATIAKEVHLIANKPEFK
CCEEEECCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHH
AERQMVEIVKNTSNIKIHYNKQTFEFFGEEFLQGLRFKDLVTNEITTLNVEANFTFIGLL
HHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCEEEEEEEECEEEEEEE
PSRINASNLNIFNETNGFITTNKNMETNVHGIFAAGDIVDKSVRQIATAINDGVIAALYA
CCCCCCCCCEEEECCCCEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEEEH
KEYITRNN
HHHHCCCC
>Mature Secondary Structure
MNQQIYDLVIIGAGPAGLAAAVYAKRSGLNVIIVEKQFPGGKVALTANVENYLGINSISG
CCCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECHHHHCCCCCCCC
PELAYKMYEQVLNLDILVIYELADEITLKEKYKEVKLATQTLIAKTVIIATGTENRRLNI
HHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEC
PGELTFENKGISYCAICDGPLYKNKVVSVIGSGNSAVEEAIYLATIAKEVHLIANKPEFK
CCEEEECCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHEEEECCCCHH
AERQMVEIVKNTSNIKIHYNKQTFEFFGEEFLQGLRFKDLVTNEITTLNVEANFTFIGLL
HHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHCCCEEEEEEEECEEEEEEE
PSRINASNLNIFNETNGFITTNKNMETNVHGIFAAGDIVDKSVRQIATAINDGVIAALYA
CCCCCCCCCEEEECCCCEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCEEEEEEH
KEYITRNN
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]