| Definition | Ureaplasma urealyticum serovar 10 str. ATCC 33699 chromosome, complete genome. |
|---|---|
| Accession | NC_011374 |
| Length | 874,478 |
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The map label for this gene is tuf [H]
Identifier: 209554179
GI number: 209554179
Start: 732678
End: 733862
Strand: Reverse
Name: tuf [H]
Synonym: UUR10_0611
Alternate gene names: 209554179
Gene position: 733862-732678 (Counterclockwise)
Preceding gene: 209554189
Following gene: 209554097
Centisome position: 83.92
GC content: 37.47
Gene sequence:
>1185_bases ATGGCTAAAGCTAAATTTGAAAGAACAAAACCTCACGTTAACATTGGTACTATTGGCCACGTTGACCATGGTAAAACTAC TTTAACAGCTGCAATTAGTACAGTACTTGCTAAAAAAGGACAAGCTATTGCACAATCATATGCTGATGTTGATAAAACAC CAGAAGAAAGAGAACGTGGTATTACAATTAACGCTTCTCACGTTGAATATGAAACAAAAACTCGTCACTATGCACACGTT GACTGCCCAGGACACGCCGACTACGTTAAGAATATGATTACAGGTGCAGCACAAATGGATGGTGCAATCTTAGTTATTGC TGCATCTGATGGGGTTATGGCTCAAACTAAAGAACACATCCTATTAGCGCGTCAAGTTGGTGTTCCAAAAATCGTTGTAT TCTTAAATAAATGTGATTTCATGACAGATCCAGATATGCAAGATCTTGTTGAAATGGAAGTTCGTGAATTATTAACTAAA TATGGATTTGATGGCGATAACACGCCAGTTATCCGTGGTTCAGGTCTTAAAGCTTTAGAGGGCGACCCAGTATGAGAAGC TAAAATTGATGAATTAATGGATGCAGTTGACTCATGAATTCCATTACCAGAACGTAGTACTGACAAACCATTCTTATTAG CAATTGAAGACGTATTTACAATTTCAGGACGTGGTACAGTTGTAACTGGACGTGTTGAACGTGGTACATTAAAAGTTAAT GATGAAGTTGAAATCGTTGGTTTAAAAGACACTCAAAAAACTGTTGTTACAGGAATTGAAATGTTTAGAAAATCATTAGA TCAAGCTGAAGCTGGAGATAATGCTGGTATTTTATTACGTGGTATTAAAAAAGAAGACGTTGAACGTGGACAAGTACTTG TAAAACCAGGTTCAATTAAACCTCACCGTACATTTACTGCTAAAGTTTATATTCTTAAAAAAGAAGAAGGTGGACGTCAC ACACCTATCGTTTCAGGATACCGTCCACAATTCTACTTTAGAACAACAGACGTAACAGGTGCTATTTCATTACCAGCTGG TGTTGACTTAGTAATGCCTGGTGATGACGTTGAAATGACTGTAGAATTAATTGCCCCAGTTGCGATTGAAGATGGATCTA AGTTCTCAATCCGTGAAGGTGGTAAAACTGTAGGTCATGGTAGCGTAATTAAAACAAGCAACTAA
Upstream 100 bases:
>100_bases AATCTAAAAAGTTAAAATGTTATAATTTTAAGGTATAATACCTTTATTATGTATTCAAAAATTATTTAGAAAAATAAATT AATTTTCAAGGAGAATTAAA
Downstream 100 bases:
>100_bases TTTTAATAGTTTGCAATAATTAAAAATTAAAAAATGACTAAGTGTATTAGACTTGGTCATTTTTTGTATAAATTCATAAA GGAAATTTTATTTTACATGA
Product: elongation factor Tu
Products: GDP; phosphate
Alternate protein names: EF-Tu [H]
Number of amino acids: Translated: 394; Mature: 393
Protein sequence:
>394_residues MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISTVLAKKGQAIAQSYADVDKTPEERERGITINASHVEYETKTRHYAHV DCPGHADYVKNMITGAAQMDGAILVIAASDGVMAQTKEHILLARQVGVPKIVVFLNKCDFMTDPDMQDLVEMEVRELLTK YGFDGDNTPVIRGSGLKALEGDPVWEAKIDELMDAVDSWIPLPERSTDKPFLLAIEDVFTISGRGTVVTGRVERGTLKVN DEVEIVGLKDTQKTVVTGIEMFRKSLDQAEAGDNAGILLRGIKKEDVERGQVLVKPGSIKPHRTFTAKVYILKKEEGGRH TPIVSGYRPQFYFRTTDVTGAISLPAGVDLVMPGDDVEMTVELIAPVAIEDGSKFSIREGGKTVGHGSVIKTSN
Sequences:
>Translated_394_residues MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISTVLAKKGQAIAQSYADVDKTPEERERGITINASHVEYETKTRHYAHV DCPGHADYVKNMITGAAQMDGAILVIAASDGVMAQTKEHILLARQVGVPKIVVFLNKCDFMTDPDMQDLVEMEVRELLTK YGFDGDNTPVIRGSGLKALEGDPV*EAKIDELMDAVDS*IPLPERSTDKPFLLAIEDVFTISGRGTVVTGRVERGTLKVN DEVEIVGLKDTQKTVVTGIEMFRKSLDQAEAGDNAGILLRGIKKEDVERGQVLVKPGSIKPHRTFTAKVYILKKEEGGRH TPIVSGYRPQFYFRTTDVTGAISLPAGVDLVMPGDDVEMTVELIAPVAIEDGSKFSIREGGKTVGHGSVIKTSN >Mature_393_residues AKAKFERTKPHVNIGTIGHVDHGKTTLTAAISTVLAKKGQAIAQSYADVDKTPEERERGITINASHVEYETKTRHYAHVD CPGHADYVKNMITGAAQMDGAILVIAASDGVMAQTKEHILLARQVGVPKIVVFLNKCDFMTDPDMQDLVEMEVRELLTKY GFDGDNTPVIRGSGLKALEGDPV*EAKIDELMDAVDS*IPLPERSTDKPFLLAIEDVFTISGRGTVVTGRVERGTLKVND EVEIVGLKDTQKTVVTGIEMFRKSLDQAEAGDNAGILLRGIKKEDVERGQVLVKPGSIKPHRTFTAKVYILKKEEGGRHT PIVSGYRPQFYFRTTDVTGAISLPAGVDLVMPGDDVEMTVELIAPVAIEDGSKFSIREGGKTVGHGSVIKTSN
Specific function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis [H]
COG id: COG0050
COG function: function code J; GTPases - translation elongation factors
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily [H]
Homologues:
Organism=Homo sapiens, GI34147630, Length=393, Percent_Identity=57.7608142493639, Blast_Score=467, Evalue=1e-131, Organism=Homo sapiens, GI4503471, Length=367, Percent_Identity=34.3324250681199, Blast_Score=167, Evalue=1e-41, Organism=Homo sapiens, GI4503475, Length=365, Percent_Identity=33.972602739726, Blast_Score=166, Evalue=5e-41, Organism=Homo sapiens, GI223555963, Length=441, Percent_Identity=29.7052154195011, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI5729864, Length=441, Percent_Identity=29.7052154195011, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI54607086, Length=312, Percent_Identity=31.7307692307692, Blast_Score=134, Evalue=1e-31, Organism=Homo sapiens, GI46094014, Length=375, Percent_Identity=29.6, Blast_Score=129, Evalue=4e-30, Organism=Homo sapiens, GI194018522, Length=374, Percent_Identity=30.2139037433155, Blast_Score=129, Evalue=5e-30, Organism=Homo sapiens, GI194097354, Length=374, Percent_Identity=30.2139037433155, Blast_Score=129, Evalue=6e-30, Organism=Homo sapiens, GI194018520, Length=374, Percent_Identity=30.2139037433155, Blast_Score=129, Evalue=6e-30, Organism=Homo sapiens, GI4503507, Length=270, Percent_Identity=28.5185185185185, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI82546879, Length=428, Percent_Identity=23.1308411214953, Blast_Score=74, Evalue=3e-13, Organism=Homo sapiens, GI53729339, Length=227, Percent_Identity=32.5991189427313, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI53729337, Length=227, Percent_Identity=32.5991189427313, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI25306287, Length=128, Percent_Identity=35.9375, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI25306283, Length=128, Percent_Identity=35.9375, Blast_Score=67, Evalue=4e-11, Organism=Homo sapiens, GI19923640, Length=128, Percent_Identity=35.9375, Blast_Score=67, Evalue=4e-11, Organism=Escherichia coli, GI1789737, Length=391, Percent_Identity=71.0997442455243, Blast_Score=559, Evalue=1e-160, Organism=Escherichia coli, GI1790412, Length=391, Percent_Identity=71.0997442455243, Blast_Score=559, Evalue=1e-160, Organism=Escherichia coli, GI2367247, Length=330, Percent_Identity=32.4242424242424, Blast_Score=147, Evalue=1e-36, Organism=Escherichia coli, GI48994988, Length=277, Percent_Identity=30.6859205776173, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1789108, Length=265, Percent_Identity=27.9245283018868, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1788922, Length=381, Percent_Identity=27.0341207349081, Blast_Score=72, Evalue=8e-14, Organism=Escherichia coli, GI1789738, Length=146, Percent_Identity=33.5616438356164, Blast_Score=63, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17556456, Length=393, Percent_Identity=52.9262086513995, Blast_Score=392, Evalue=1e-109, Organism=Caenorhabditis elegans, GI25141371, Length=369, Percent_Identity=47.6964769647696, Blast_Score=352, Evalue=2e-97, Organism=Caenorhabditis elegans, GI17552884, Length=368, Percent_Identity=34.7826086956522, Blast_Score=171, Evalue=4e-43, Organism=Caenorhabditis elegans, GI17569207, Length=368, Percent_Identity=34.7826086956522, Blast_Score=171, Evalue=4e-43, Organism=Caenorhabditis elegans, GI32566303, Length=345, Percent_Identity=34.7826086956522, Blast_Score=150, Evalue=1e-36, Organism=Caenorhabditis elegans, GI115532067, Length=436, Percent_Identity=27.9816513761468, Blast_Score=137, Evalue=1e-32, Organism=Caenorhabditis elegans, GI115532065, Length=436, Percent_Identity=27.9816513761468, Blast_Score=136, Evalue=2e-32, Organism=Caenorhabditis elegans, GI17506081, Length=270, Percent_Identity=32.5925925925926, Blast_Score=131, Evalue=7e-31, Organism=Caenorhabditis elegans, GI32566629, Length=453, Percent_Identity=27.1523178807947, Blast_Score=124, Evalue=8e-29, Organism=Caenorhabditis elegans, GI32566301, Length=145, Percent_Identity=40.6896551724138, Blast_Score=94, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17557151, Length=231, Percent_Identity=29.8701298701299, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17509919, Length=276, Percent_Identity=27.536231884058, Blast_Score=82, Evalue=5e-16, Organism=Caenorhabditis elegans, GI71994658, Length=236, Percent_Identity=33.8983050847458, Blast_Score=73, Evalue=3e-13, Organism=Saccharomyces cerevisiae, GI6324761, Length=395, Percent_Identity=63.5443037974684, Blast_Score=502, Evalue=1e-143, Organism=Saccharomyces cerevisiae, GI6325337, Length=363, Percent_Identity=32.5068870523416, Blast_Score=156, Evalue=7e-39, Organism=Saccharomyces cerevisiae, GI6319594, Length=363, Percent_Identity=32.5068870523416, Blast_Score=156, Evalue=7e-39, Organism=Saccharomyces cerevisiae, GI6322937, Length=363, Percent_Identity=26.4462809917355, Blast_Score=102, Evalue=8e-23, Organism=Saccharomyces cerevisiae, GI6320377, Length=439, Percent_Identity=27.5626423690205, Blast_Score=96, Evalue=1e-20, Organism=Saccharomyces cerevisiae, GI6320863, Length=271, Percent_Identity=28.7822878228782, Blast_Score=86, Evalue=9e-18, Organism=Saccharomyces cerevisiae, GI6323320, Length=237, Percent_Identity=30.8016877637131, Blast_Score=80, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6323098, Length=142, Percent_Identity=36.6197183098592, Blast_Score=74, Evalue=4e-14, Organism=Drosophila melanogaster, GI281363316, Length=392, Percent_Identity=55.6122448979592, Blast_Score=446, Evalue=1e-125, Organism=Drosophila melanogaster, GI17864358, Length=392, Percent_Identity=55.6122448979592, Blast_Score=446, Evalue=1e-125, Organism=Drosophila melanogaster, GI19921738, Length=386, Percent_Identity=49.4818652849741, Blast_Score=387, Evalue=1e-108, Organism=Drosophila melanogaster, GI45553807, Length=382, Percent_Identity=33.2460732984293, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI45553816, Length=382, Percent_Identity=33.2460732984293, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI24651721, Length=382, Percent_Identity=33.2460732984293, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI17864154, Length=382, Percent_Identity=33.2460732984293, Blast_Score=166, Evalue=2e-41, Organism=Drosophila melanogaster, GI24652838, Length=447, Percent_Identity=30.6487695749441, Blast_Score=161, Evalue=7e-40, Organism=Drosophila melanogaster, GI17137572, Length=447, Percent_Identity=30.6487695749441, Blast_Score=161, Evalue=7e-40, Organism=Drosophila melanogaster, GI45550900, Length=358, Percent_Identity=30.7262569832402, Blast_Score=138, Evalue=6e-33, Organism=Drosophila melanogaster, GI19922690, Length=302, Percent_Identity=30.794701986755, Blast_Score=137, Evalue=2e-32, Organism=Drosophila melanogaster, GI17137380, Length=354, Percent_Identity=31.0734463276836, Blast_Score=131, Evalue=7e-31, Organism=Drosophila melanogaster, GI24647048, Length=273, Percent_Identity=28.9377289377289, Blast_Score=90, Evalue=3e-18, Organism=Drosophila melanogaster, GI24647046, Length=273, Percent_Identity=28.9377289377289, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI78706572, Length=245, Percent_Identity=30.2040816326531, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI28572034, Length=175, Percent_Identity=36.5714285714286, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI24582462, Length=163, Percent_Identity=31.9018404907975, Blast_Score=67, Evalue=3e-11,
Paralogues:
None
Copy number: 20568 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000795 - InterPro: IPR005225 - InterPro: IPR009001 - InterPro: IPR004161 - InterPro: IPR004541 - InterPro: IPR004160 - InterPro: IPR009000 [H]
Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF03143 GTP_EFTU_D3 [H]
EC number: 3.6.5.3
Molecular weight: Translated: 42510; Mature: 42379
Theoretical pI: Translated: 6.15; Mature: 6.15
Prosite motif: PS00301 EFACTOR_GTP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISTVLAKKGQAIAQSYADVDKTPEERERG CCCCCCCCCCCCEEECEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCC ITINASHVEYETKTRHYAHVDCPGHADYVKNMITGAAQMDGAILVIAASDGVMAQTKEHI EEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCHHHCCCEEEEEECCCCCCHHHHHHE LLARQVGVPKIVVFLNKCDFMTDPDMQDLVEMEVRELLTKYGFDGDNTPVIRGSGLKALE EEEHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC GDPVEAKIDELMDAVDSIPLPERSTDKPFLLAIEDVFTISGRGTVVTGRVERGTLKVNDE CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEECCEEEECCC VEIVGLKDTQKTVVTGIEMFRKSLDQAEAGDNAGILLRGIKKEDVERGQVLVKPGSIKPH EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHCCCCCEEEEECCCCCCC RTFTAKVYILKKEEGGRHTPIVSGYRPQFYFRTTDVTGAISLPAGVDLVMPGDDVEMTVE CEEEEEEEEEEECCCCCCCCEECCCCCEEEEEECCCCEEEECCCCEEEEECCCCCEEEEE LIAPVAIEDGSKFSIREGGKTVGHGSVIKTSN EEEEEEECCCCEEEECCCCCCCCCCCEEEECC >Mature Secondary Structure AKAKFERTKPHVNIGTIGHVDHGKTTLTAAISTVLAKKGQAIAQSYADVDKTPEERERG CCCCCCCCCCCEEECEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCC ITINASHVEYETKTRHYAHVDCPGHADYVKNMITGAAQMDGAILVIAASDGVMAQTKEHI EEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCHHHCCCEEEEEECCCCCCHHHHHHE LLARQVGVPKIVVFLNKCDFMTDPDMQDLVEMEVRELLTKYGFDGDNTPVIRGSGLKALE EEEHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCC GDPVEAKIDELMDAVDSIPLPERSTDKPFLLAIEDVFTISGRGTVVTGRVERGTLKVNDE CCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEECCEEEECCC VEIVGLKDTQKTVVTGIEMFRKSLDQAEAGDNAGILLRGIKKEDVERGQVLVKPGSIKPH EEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHCCCCCEEEEECCCCCCC RTFTAKVYILKKEEGGRHTPIVSGYRPQFYFRTTDVTGAISLPAGVDLVMPGDDVEMTVE CEEEEEEEEEEECCCCCCCCEECCCCCEEEEEECCCCEEEECCCCEEEEECCCCCEEEEE LIAPVAIEDGSKFSIREGGKTVGHGSVIKTSN EEEEEEECCCCEEEECCCCCCCCCCCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: GTP; H2O
Specific reaction: GTP + H2O = GDP + phosphate
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA