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The map label for this gene is ureC [H]

Identifier: 209554177

GI number: 209554177

Start: 526768

End: 528564

Strand: Reverse

Name: ureC [H]

Synonym: UUR10_0477

Alternate gene names: 209554177

Gene position: 528564-526768 (Counterclockwise)

Preceding gene: 209554211

Following gene: 209554123

Centisome position: 60.44

GC content: 36.95

Gene sequence:

>1797_bases
ATGTTTAAAATTTCAAGAAAAAATTACTCAGATCTATATGGTATCACAACTGGTGATAGCGTTAGATTAGGAGACACAAA
TCTTTGAGTTAAAGTTGAAAAAGACTTAACTACTTATGGTGAAGAGTCTGTCTTCGGTGGTGGTAAAACTCTACGTGAAG
GTATGGGGATGAACTCTACTATGAAGTTAGACGACAAGTTAGGGAATGCTGAAGTAATGGACTTAGTTATTACAAACGCA
TTAATTCTTGACTACACAGGTATCTACAAAGCTGATATCGGTATTAAAAACGGAAAAATTGCATCTATTGGTAAATCAGG
TAACCCTCATTTAACTGATGGAGTAGACATGGTTGTTGGTATTTCAACTGAAGTTTCAGCTGGTGAAGGTAAAATTTATA
CAGCTGGTGGTTTAGATACTCACGTTCACTGATTAGAACCAGAAATTGTTCCAGTAGCATTAGATGGTGGTATTACAACT
GTTATTGCTGGTGGTACAGGTATGAACGATGGTACAAAAGCTACAACTGTTTCACCTGGTAAATTCTGAGTTAAATCTGC
TTTACAAGCAGCTGATGGATTACCAATTAACGCAGGTTTCTTAGCTAAAGGTCAAGGTATGGAAGATCCAATCTTTGAAC
AAATCGTAGCAGGTGCTTGTGGTCTTAAGATTCACGAAGACTGAGGGGCAACAGGAAACGCTATTGACTTAGCATTAACA
GTTGCTGAAAAAACTGATGTAGCTGTTGCTATCCATACAGATACATTAAACGAAGCAGGATTTGTTGAACATACAATTGC
TGCAATGAAAGGACGTACAATCCACGCTTACCATACAGAAGGTGCTGGTGGTGGACATGCTCCAGATATTCTAGAATCTG
TTAAATATGCACATATTTTACCAGCTTCTACAAACCCAACTATTCCATATACAGTAAACACAATTGCAGAACACTTAGAT
ATGTTAATGGTATGTCACCACTTAAATCCTAAGGTTCCAGAAGACGTTGCTTTTGCTGACTCACGTATTCGTAGCCAAAC
AATTGCAGCTGAAGACTTACTACACGATATGGGTGCAATCTCAATTATGTCATCAGATACATTAGCTATGGGACGTATTG
GTGAAGTTGTAACTCGTTCATGACAAATGGCTCACAAAATGAAAGCTCAATTTGGTGCATTAAAAGGGGATAGCGAATTT
AACGATAACAACCGTGTAAAACGTTATGTTGCTAAATATACAATTAACCCAGCTATTGCTCATGGTATTGACTCATACGT
TGGATCAATCGAAGTAGGAAAATTAGCTGATATTGTTGCATGAGAACCTAAATTCTTTGGTGCAAAACCTTACTATGTTG
TAAAAATGGGTGTAATTGCTCGTTGTGTAGCAGGGGATCCAAACGCTTCAATTCCAACATGTGAACCAGTAATTATGCGT
GATCAATTTGGAACATATGGACGTTCATTAACTAGCACATCAGTAAGCTTTGTTTCAAAAATTGGTCTAGAAAATGGAAT
TAAAGAAGAATACAAACTAGAAAAAGAATTATTACCAGTTAAGAATTGCCGTTCAATCAACAAGAAGAGCATGAAATGAA
ACTCAGCAACTCCAAATCTAGAAGTTGATCCTCAAACATTTGATGCTGCTGTTGACTACAACGACTTAGAAAACTGATTA
GAACAACCAGCTGCTGAATTAGCTAAGAAATTAAAGAAAACTGCAAACGGTAAATACGTACTTGATGCAGAACCTCTAAC
AGAAGCTCCATTAGCACAAAGATACTTCTTATTCTAA

Upstream 100 bases:

>100_bases
TAGTCGGAACACGTGAAGTTTGAGGTGTAAACGGCTTAGTTAACGGAAAACTTAAAAAATAATCTATTTACAAGTTTCTA
TATAGACGAAGGGGAACATT

Downstream 100 bases:

>100_bases
TTCTTGAATTATTTTGATTTAGTAATTCAATTTCCAACTACATTTAAAAGAAGCGAGGTATAAATCTTGACTGTATTTAA
AGAAATTTTAGGTAACATTA

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MFKISRKNYSDLYGITTGDSVRLGDTNLWVKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNA
LILDYTGIYKADIGIKNGKIASIGKSGNPHLTDGVDMVVGISTEVSAGEGKIYTAGGLDTHVHWLEPEIVPVALDGGITT
VIAGGTGMNDGTKATTVSPGKFWVKSALQAADGLPINAGFLAKGQGMEDPIFEQIVAGACGLKIHEDWGATGNAIDLALT
VAEKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILESVKYAHILPASTNPTIPYTVNTIAEHLD
MLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVVTRSWQMAHKMKAQFGALKGDSEF
NDNNRVKRYVAKYTINPAIAHGIDSYVGSIEVGKLADIVAWEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMR
DQFGTYGRSLTSTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSINKKSMKWNSATPNLEVDPQTFDAAVDYNDLENWL
EQPAAELAKKLKKTANGKYVLDAEPLTEAPLAQRYFLF

Sequences:

>Translated_598_residues
MFKISRKNYSDLYGITTGDSVRLGDTNL*VKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNA
LILDYTGIYKADIGIKNGKIASIGKSGNPHLTDGVDMVVGISTEVSAGEGKIYTAGGLDTHVH*LEPEIVPVALDGGITT
VIAGGTGMNDGTKATTVSPGKF*VKSALQAADGLPINAGFLAKGQGMEDPIFEQIVAGACGLKIHED*GATGNAIDLALT
VAEKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILESVKYAHILPASTNPTIPYTVNTIAEHLD
MLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVVTRS*QMAHKMKAQFGALKGDSEF
NDNNRVKRYVAKYTINPAIAHGIDSYVGSIEVGKLADIVA*EPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMR
DQFGTYGRSLTSTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSINKKSMK*NSATPNLEVDPQTFDAAVDYNDLEN*L
EQPAAELAKKLKKTANGKYVLDAEPLTEAPLAQRYFLF
>Mature_598_residues
MFKISRKNYSDLYGITTGDSVRLGDTNL*VKVEKDLTTYGEESVFGGGKTLREGMGMNSTMKLDDKLGNAEVMDLVITNA
LILDYTGIYKADIGIKNGKIASIGKSGNPHLTDGVDMVVGISTEVSAGEGKIYTAGGLDTHVH*LEPEIVPVALDGGITT
VIAGGTGMNDGTKATTVSPGKF*VKSALQAADGLPINAGFLAKGQGMEDPIFEQIVAGACGLKIHED*GATGNAIDLALT
VAEKTDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILESVKYAHILPASTNPTIPYTVNTIAEHLD
MLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMSSDTLAMGRIGEVVTRS*QMAHKMKAQFGALKGDSEF
NDNNRVKRYVAKYTINPAIAHGIDSYVGSIEVGKLADIVA*EPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMR
DQFGTYGRSLTSTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSINKKSMK*NSATPNLEVDPQTFDAAVDYNDLEN*L
EQPAAELAKKLKKTANGKYVLDAEPLTEAPLAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the urease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 62857; Mature: 62857

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKISRKNYSDLYGITTGDSVRLGDTNLVKVEKDLTTYGEESVFGGGKTLREGMGMNSTM
CCEECCCCCCCEEEECCCCEEEECCCCEEEEEHHHHHCCCCCCCCCCHHHHHCCCCCCEE
KLDDKLGNAEVMDLVITNALILDYTGIYKADIGIKNGKIASIGKSGNPHLTDGVDMVVGI
EECCCCCCHHHHHHHHHHHHEEECCCEEEECCCCCCCEEEECCCCCCCCCCCCCEEEEEE
STEVSAGEGKIYTAGGLDTHVHLEPEIVPVALDGGITTVIAGGTGMNDGTKATTVSPGKF
CCCCCCCCCEEEECCCCCEEEEECCCEEEEEECCCEEEEEECCCCCCCCCCEEEECCHHH
VKSALQAADGLPINAGFLAKGQGMEDPIFEQIVAGACGLKIHEDGATGNAIDLALTVAEK
HHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEEEEEEECC
TDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILESVKYAHILPAST
CCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCC
NPTIPYTVNTIAEHLDMLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SDTLAMGRIGEVVTRSQMAHKMKAQFGALKGDSEFNDNNRVKRYVAKYTINPAIAHGIDS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
YVGSIEVGKLADIVAEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMRDQFGTY
HHCCEEHHHHHHHHCCCCCCCCCCEEEEEHHHHHHEECCCCCCCCCCCCCEEEECCCCCC
GRSLTSTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSINKKSMKNSATPNLEVDPQTF
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCHH
DAAVDYNDLENLEQPAAELAKKLKKTANGKYVLDAEPLTEAPLAQRYFLF
CEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHCCC
>Mature Secondary Structure
MFKISRKNYSDLYGITTGDSVRLGDTNLVKVEKDLTTYGEESVFGGGKTLREGMGMNSTM
CCEECCCCCCCEEEECCCCEEEECCCCEEEEEHHHHHCCCCCCCCCCHHHHHCCCCCCEE
KLDDKLGNAEVMDLVITNALILDYTGIYKADIGIKNGKIASIGKSGNPHLTDGVDMVVGI
EECCCCCCHHHHHHHHHHHHEEECCCEEEECCCCCCCEEEECCCCCCCCCCCCCEEEEEE
STEVSAGEGKIYTAGGLDTHVHLEPEIVPVALDGGITTVIAGGTGMNDGTKATTVSPGKF
CCCCCCCCCEEEECCCCCEEEEECCCEEEEEECCCEEEEEECCCCCCCCCCEEEECCHHH
VKSALQAADGLPINAGFLAKGQGMEDPIFEQIVAGACGLKIHEDGATGNAIDLALTVAEK
HHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEEEEEEECC
TDVAVAIHTDTLNEAGFVEHTIAAMKGRTIHAYHTEGAGGGHAPDILESVKYAHILPAST
CCEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCC
NPTIPYTVNTIAEHLDMLMVCHHLNPKVPEDVAFADSRIRSQTIAAEDLLHDMGAISIMS
CCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
SDTLAMGRIGEVVTRSQMAHKMKAQFGALKGDSEFNDNNRVKRYVAKYTINPAIAHGIDS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
YVGSIEVGKLADIVAEPKFFGAKPYYVVKMGVIARCVAGDPNASIPTCEPVIMRDQFGTY
HHCCEEHHHHHHHHCCCCCCCCCCEEEEEHHHHHHEECCCCCCCCCCCCCEEEECCCCCC
GRSLTSTSVSFVSKIGLENGIKEEYKLEKELLPVKNCRSINKKSMKNSATPNLEVDPQTF
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCHH
DAAVDYNDLENLEQPAAELAKKLKKTANGKYVLDAEPLTEAPLAQRYFLF
CEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10555372 [H]