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The map label for this gene is ftsK [H]

Identifier: 209554061

GI number: 209554061

Start: 707291

End: 709621

Strand: Reverse

Name: ftsK [H]

Synonym: UUR10_0590

Alternate gene names: 209554061

Gene position: 709621-707291 (Counterclockwise)

Preceding gene: 209554147

Following gene: 209554384

Centisome position: 81.15

GC content: 23.81

Gene sequence:

>2331_bases
ATGGCTAATGACAACAAAAACAGTACACCAAATAAAGAGACGATTAGTTTTTATAGTTATGATGATCAACTAGATGAATC
AAAAAAAGAATCTAATGATTTAACAAGCGAAAATAAAACACAAGATAAAAGTTCAAAACCAAAACCAAAGAAAACTAAAT
TTTCAAAGCTTGATTTTAATAATAAAAAAAAGATTATAGGGATTTGTGTTTTTGCTTTAAGTTTTTTGATTTTATTATTT
GCGATTTTTAAAGTTCCATACACTGGAGCAATTTTAGATAATGTTTTAGAATTCTTTTTCGGATGAGTTAAATACTATAT
TTATGCAATTTTATTATTATTTTTAATTGTTTTTTACATTAAAAAAGCAAGAAAACGCTTATTTAGTAAATGGATGATTG
TTTTTTATGTTGTTACAATAATCTTATTTACTTTAATTATTGGCGCAGTTGGTTATGGTGTTATTACTCATTCATTAATT
TATAAATTTATTGTTAATACAAATCAACAAACAATTGATCAAAAAGTCCTTGATTCATACAAGAATAATTATGAATATAT
TGCATTAGTTAATTTACATGCAAAAAAATTACATTTAAGTGAATGATGAGCAGCTAATTGATCACAAGATTTTTTAAAAG
CAATTGATAAAAACCATTATTACTACACTAGCATTTTTGCTTATGGCGGGATTGTAGGATATGCTAATTTAGATATTTAT
CGTGCTAATGCTTGAATCTTTACAATCGTGATTATGTCAATAATATTAGGAATTATTTGTTTTATTTTAATCACATTTGG
CACAAGAAGTCGTTTAGGATTAAAGTTTAAAAAATGGTTTATTAATAAAATAATTGCAAATATTAATACTTATCATAAAA
AAGATTATCAATTAAATGAACGTAATTATTTTGAAGAAAAACTTGGTACAGATCACCATGGAACTAATCAACAATTTAGC
GCAAAACAAATTGTTGAGCAACAAAATATTCAAACAAAAATTACTAATAGCGAACCACCTATTAATTCACCAACATCAAA
AAATAAAAAGATTGAAGAAATAGTTTCAAACCCAATAGTTGATAATACTAATCAAGTTGTAGATAATACACCTATAACTA
AAAATAGTAAATATGAGTTTTATCCTCGAATTAGTATTATTGATGGAAAAAGCCAAGATTATTTACATGAACTTAAATCA
ATTGGTGAAAATTTAAAATTAGTTATTGATCAATTTTTAGAAAGTAATCAATTAGAATGTCAATTTAATACAATCAATAC
TTATTTTTCAAATGTAGAAATCATTTATCAATTTAGTCGTTTATCATTAAGCAACTTCATTAAAAATTATTTAAATTTAA
TGAAACAAACAATTTGTGACACTAATGAGTATGAAATTAGTATTTATAATGATAATGAGCTTTTAGTTGTCCAAGCTAAA
GCTAAGAATTTAAACGCTCAAATTAATATTAAAGATATTTTAAATGATCTTGAATACAATGATAAATTATGTTTAGGAAT
TGGTAAGCTAAAAGAACGAAGCGTTGTATGATTAGAAGATAATCAAGTTGGTAGTATTTTAGTTCATGGTAGTCAACAAG
CATCAGGAAGATCGATGTTAATTTCTAATATCATTATTAGTGCTTTATATACTAAATCACCAAATGAACTAGAATTATTT
ATTGTTAATAATGGATCAAAACCACTAAAAGAATTTGCTAAACTAAAACATACAATAAATTGTGTTGATCATGATGATTT
TGAAAATGTTATTAATCTATTAAAAACAATTGTTAATAATATTAATAATGAAAATACTTTATTTACAAATAATGGCGTTG
ATAATTTAGATGATTATAATGCAAAGAACCAAAATCAAAAATTAGCAAAAAAATTAATTATTATTTCAGAATATGCCGAA
ATAATAAATAGTGAATTTAAAACACGATTTGATACTTTAATTCGCAATATTGCAAGCGTTGCTAAAAAACATGGAATTAT
TTTAATCCTTTCATCAAGTATAACTAATGAAAACACAGTTTCATTTAAAAATGTGTTTGATTATACAATCGCATTAAAAC
TAAATAATCCATACGAAAGCATTTTATTAACTGATCGTAATTGATGTAATAATTTAAGTGGATTTGGGGATATGCTATTA
ATTCGTAATTTTGATAATTTGCCTTTACGAGTACAAACAGCTAAGGTTTCAAATGATCAATTTGCCAATATTATTAATGA
AATCAATAGTGCTGATTATGATATTAACGAATATCGTCATGAGACAAAACTAACATCAAAGACCCAAAATTTCTTTAATA
AACAATCATAA

Upstream 100 bases:

>100_bases
TTAACTAAATTGTTTGAAAAGAAATTTAACAAACGACCTTTAGTTTTACCAACTGTAGTTGATTGCTATAAAACAAAATA
ATTTTTTAGAGGTAAATACT

Downstream 100 bases:

>100_bases
TTATGTATCTTAAAATTAACGTCGTACATAATTTGAATAAAAGCATTATAATATAAGAATATTAAAACTATAAATATCAA
AGAAGGAACGGAATTTATGA

Product: cell division protein

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 776; Mature: 775

Protein sequence:

>776_residues
MANDNKNSTPNKETISFYSYDDQLDESKKESNDLTSENKTQDKSSKPKPKKTKFSKLDFNNKKKIIGICVFALSFLILLF
AIFKVPYTGAILDNVLEFFFGWVKYYIYAILLLFLIVFYIKKARKRLFSKWMIVFYVVTIILFTLIIGAVGYGVITHSLI
YKFIVNTNQQTIDQKVLDSYKNNYEYIALVNLHAKKLHLSEWWAANWSQDFLKAIDKNHYYYTSIFAYGGIVGYANLDIY
RANAWIFTIVIMSIILGIICFILITFGTRSRLGLKFKKWFINKIIANINTYHKKDYQLNERNYFEEKLGTDHHGTNQQFS
AKQIVEQQNIQTKITNSEPPINSPTSKNKKIEEIVSNPIVDNTNQVVDNTPITKNSKYEFYPRISIIDGKSQDYLHELKS
IGENLKLVIDQFLESNQLECQFNTINTYFSNVEIIYQFSRLSLSNFIKNYLNLMKQTICDTNEYEISIYNDNELLVVQAK
AKNLNAQINIKDILNDLEYNDKLCLGIGKLKERSVVWLEDNQVGSILVHGSQQASGRSMLISNIIISALYTKSPNELELF
IVNNGSKPLKEFAKLKHTINCVDHDDFENVINLLKTIVNNINNENTLFTNNGVDNLDDYNAKNQNQKLAKKLIIISEYAE
IINSEFKTRFDTLIRNIASVAKKHGIILILSSSITNENTVSFKNVFDYTIALKLNNPYESILLTDRNWCNNLSGFGDMLL
IRNFDNLPLRVQTAKVSNDQFANIINEINSADYDINEYRHETKLTSKTQNFFNKQS

Sequences:

>Translated_776_residues
MANDNKNSTPNKETISFYSYDDQLDESKKESNDLTSENKTQDKSSKPKPKKTKFSKLDFNNKKKIIGICVFALSFLILLF
AIFKVPYTGAILDNVLEFFFG*VKYYIYAILLLFLIVFYIKKARKRLFSKWMIVFYVVTIILFTLIIGAVGYGVITHSLI
YKFIVNTNQQTIDQKVLDSYKNNYEYIALVNLHAKKLHLSE**AAN*SQDFLKAIDKNHYYYTSIFAYGGIVGYANLDIY
RANA*IFTIVIMSIILGIICFILITFGTRSRLGLKFKKWFINKIIANINTYHKKDYQLNERNYFEEKLGTDHHGTNQQFS
AKQIVEQQNIQTKITNSEPPINSPTSKNKKIEEIVSNPIVDNTNQVVDNTPITKNSKYEFYPRISIIDGKSQDYLHELKS
IGENLKLVIDQFLESNQLECQFNTINTYFSNVEIIYQFSRLSLSNFIKNYLNLMKQTICDTNEYEISIYNDNELLVVQAK
AKNLNAQINIKDILNDLEYNDKLCLGIGKLKERSVV*LEDNQVGSILVHGSQQASGRSMLISNIIISALYTKSPNELELF
IVNNGSKPLKEFAKLKHTINCVDHDDFENVINLLKTIVNNINNENTLFTNNGVDNLDDYNAKNQNQKLAKKLIIISEYAE
IINSEFKTRFDTLIRNIASVAKKHGIILILSSSITNENTVSFKNVFDYTIALKLNNPYESILLTDRN*CNNLSGFGDMLL
IRNFDNLPLRVQTAKVSNDQFANIINEINSADYDINEYRHETKLTSKTQNFFNKQS
>Mature_775_residues
ANDNKNSTPNKETISFYSYDDQLDESKKESNDLTSENKTQDKSSKPKPKKTKFSKLDFNNKKKIIGICVFALSFLILLFA
IFKVPYTGAILDNVLEFFFG*VKYYIYAILLLFLIVFYIKKARKRLFSKWMIVFYVVTIILFTLIIGAVGYGVITHSLIY
KFIVNTNQQTIDQKVLDSYKNNYEYIALVNLHAKKLHLSE**AAN*SQDFLKAIDKNHYYYTSIFAYGGIVGYANLDIYR
ANA*IFTIVIMSIILGIICFILITFGTRSRLGLKFKKWFINKIIANINTYHKKDYQLNERNYFEEKLGTDHHGTNQQFSA
KQIVEQQNIQTKITNSEPPINSPTSKNKKIEEIVSNPIVDNTNQVVDNTPITKNSKYEFYPRISIIDGKSQDYLHELKSI
GENLKLVIDQFLESNQLECQFNTINTYFSNVEIIYQFSRLSLSNFIKNYLNLMKQTICDTNEYEISIYNDNELLVVQAKA
KNLNAQINIKDILNDLEYNDKLCLGIGKLKERSVV*LEDNQVGSILVHGSQQASGRSMLISNIIISALYTKSPNELELFI
VNNGSKPLKEFAKLKHTINCVDHDDFENVINLLKTIVNNINNENTLFTNNGVDNLDDYNAKNQNQKLAKKLIIISEYAEI
INSEFKTRFDTLIRNIASVAKKHGIILILSSSITNENTVSFKNVFDYTIALKLNNPYESILLTDRN*CNNLSGFGDMLLI
RNFDNLPLRVQTAKVSNDQFANIINEINSADYDINEYRHETKLTSKTQNFFNKQS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88263; Mature: 88132

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANDNKNSTPNKETISFYSYDDQLDESKKESNDLTSENKTQDKSSKPKPKKTKFSKLDFN
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NKKKIIGICVFALSFLILLFAIFKVPYTGAILDNVLEFFFGVKYYIYAILLLFLIVFYIK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARKRLFSKWMIVFYVVTIILFTLIIGAVGYGVITHSLIYKFIVNTNQQTIDQKVLDSYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NNYEYIALVNLHAKKLHLSEAANSQDFLKAIDKNHYYYTSIFAYGGIVGYANLDIYRANA
CCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCEEEEEHHHHCCEEEEEEEEEEECHH
IFTIVIMSIILGIICFILITFGTRSRLGLKFKKWFINKIIANINTYHKKDYQLNERNYFE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
EKLGTDHHGTNQQFSAKQIVEQQNIQTKITNSEPPINSPTSKNKKIEEIVSNPIVDNTNQ
HHCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
VVDNTPITKNSKYEFYPRISIIDGKSQDYLHELKSIGENLKLVIDQFLESNQLECQFNTI
CCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEH
NTYFSNVEIIYQFSRLSLSNFIKNYLNLMKQTICDTNEYEISIYNDNELLVVQAKAKNLN
HHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCC
AQINIKDILNDLEYNDKLCLGIGKLKERSVVLEDNQVGSILVHGSQQASGRSMLISNIII
CEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHH
SALYTKSPNELELFIVNNGSKPLKEFAKLKHTINCVDHDDFENVINLLKTIVNNINNENT
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCE
LFTNNGVDNLDDYNAKNQNQKLAKKLIIISEYAEIINSEFKTRFDTLIRNIASVAKKHGI
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
ILILSSSITNENTVSFKNVFDYTIALKLNNPYESILLTDRNCNNLSGFGDMLLIRNFDNL
EEEEECCCCCCCCEEHHEEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEECCCCC
PLRVQTAKVSNDQFANIINEINSADYDINEYRHETKLTSKTQNFFNKQS
CEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANDNKNSTPNKETISFYSYDDQLDESKKESNDLTSENKTQDKSSKPKPKKTKFSKLDFN
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NKKKIIGICVFALSFLILLFAIFKVPYTGAILDNVLEFFFGVKYYIYAILLLFLIVFYIK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KARKRLFSKWMIVFYVVTIILFTLIIGAVGYGVITHSLIYKFIVNTNQQTIDQKVLDSYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
NNYEYIALVNLHAKKLHLSEAANSQDFLKAIDKNHYYYTSIFAYGGIVGYANLDIYRANA
CCCEEEEEEECCHHHHHHHHHCCHHHHHHHHHCCCEEEEEHHHHCCEEEEEEEEEEECHH
IFTIVIMSIILGIICFILITFGTRSRLGLKFKKWFINKIIANINTYHKKDYQLNERNYFE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
EKLGTDHHGTNQQFSAKQIVEQQNIQTKITNSEPPINSPTSKNKKIEEIVSNPIVDNTNQ
HHCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
VVDNTPITKNSKYEFYPRISIIDGKSQDYLHELKSIGENLKLVIDQFLESNQLECQFNTI
CCCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEH
NTYFSNVEIIYQFSRLSLSNFIKNYLNLMKQTICDTNEYEISIYNDNELLVVQAKAKNLN
HHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCC
AQINIKDILNDLEYNDKLCLGIGKLKERSVVLEDNQVGSILVHGSQQASGRSMLISNIII
CEEEHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHH
SALYTKSPNELELFIVNNGSKPLKEFAKLKHTINCVDHDDFENVINLLKTIVNNINNENT
HHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCE
LFTNNGVDNLDDYNAKNQNQKLAKKLIIISEYAEIINSEFKTRFDTLIRNIASVAKKHGI
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
ILILSSSITNENTVSFKNVFDYTIALKLNNPYESILLTDRNCNNLSGFGDMLLIRNFDNL
EEEEECCCCCCCCEEHHEEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEECCCCC
PLRVQTAKVSNDQFANIINEINSADYDINEYRHETKLTSKTQNFFNKQS
CEEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]