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The map label for this gene is obgE [H]

Identifier: 209554030

GI number: 209554030

Start: 556879

End: 558186

Strand: Reverse

Name: obgE [H]

Synonym: UUR10_0505

Alternate gene names: 209554030

Gene position: 558186-556879 (Counterclockwise)

Preceding gene: 209554000

Following gene: 209554252

Centisome position: 63.83

GC content: 28.98

Gene sequence:

>1308_bases
ATGGCATTCATTGATAAATGTAAGATTGTATTAATTGCTGGCAATGGTGGTGATGGGATTGTTTCATGACGACGTGAGAC
CCATGTTCCAGAAGGTGGTCCAGCTGGGGGAAATGGTGGTAATGGTGGTTCAATTTGATTTGTTGGAAATCATAATGAAA
CCTCATTAGAATTTTTAAAATACAAAAAAATTATTCGTGCTAAACACGGCGAAAAAGGCGATATTAAAAATCAACATGGT
GCGAATGCTGAAGATGTTTTTATTAATGTGCCATTAGGAACAGTTGTTTATGATGCTATTACAAATGAAATCTTAGCTGA
TATTAATATTGACCAACAAAAATATTTGGTTGCTCAAGGTGGTTTGGGTGGTCATGGAAACACACATTTTAAATCAGCTT
TTAATAAAGCTCCAAATCTTTATGAATTAGGAGAATTGGGCGAAAATATTGAAGTTGTACTAGAATTAAAAACCATTGCT
GATATTGGCATTATTGGTTTACCAAATGCTGGAAAATCAACTTTAATTTCTTCTTTTACAAATGCTAAACCTAAAACTGC
TAATTACATGTTTACAACACTAAATCCTGTTTTAGGAACAATTTATCGTGATCAAAATCGGATTATTTTTGCTGACATTC
CAGGCTTGATTGAAGGAGCGCATACTGGTGTTGGTTTAGGTCATGATTTTTTAAAACACATTGAGCGTTGTTTTTTATTA
ATTCACTTAATTTCTTTAGATCCAAATGATAACTCTGATATTATTAGTGCTTATGAAACTATTGTTAATGAACTAAAACA
ATACAAACAAAGTTTAGTTAATAAACCAATTGTTTTAGTTGCTAATAAAATTGATCAAATTGGAGCGTTAGAAAATTTAC
AAATCCTTAAAGAGCATTTAAAAGATAATCAATATATTAAAGTTATTTCAGCATTAACAAATTTACATGTTGATGCAATG
TTAGATGATGTGATAAAAATCTATTTTGATCAAAAAAAGATTTATGAACAACGTTTAAAAGAACATTTACCAGTTGATCA
AATTTTAAAATGAGCAAGTGATACTCCTAAAAATAAAGAATTAGATAAAACGATAAAAATCGTCAAAGTTGATGATCATT
TTTTTGAAGTTTTTGGTGAATATTTAAAATATTGAGTTCATCGTATTCCTTTAAAAACTCAAGATAATTTAATTCGGTTT
AATCAAAAACTTCAAAGTATTAATTTTAACCAACAATTATTACAAGCTGGCGCAATAGCTGGTGATAGTATTAAAATATA
TGATATTACATTAGAATTTGAAGAGTAA

Upstream 100 bases:

>100_bases
ATAATGAGTTTAACAAAAAACGTTTAGAATTAAAAAAACGTAATAAAGCAAATGAAAAAACAAAATATAAAGTAGAAGAT
GATTATGAAGGAAAATAAGC

Downstream 100 bases:

>100_bases
GTAAACTATGAATAATGATTTAGTTAAATATTTACAATGATTAAAAAATGATTTTATTAAGTTTTTAAATGATGCTCAAA
CTAATAATATTATTTTAGGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MAFIDKCKIVLIAGNGGDGIVSWRRETHVPEGGPAGGNGGNGGSIWFVGNHNETSLEFLKYKKIIRAKHGEKGDIKNQHG
ANAEDVFINVPLGTVVYDAITNEILADINIDQQKYLVAQGGLGGHGNTHFKSAFNKAPNLYELGELGENIEVVLELKTIA
DIGIIGLPNAGKSTLISSFTNAKPKTANYMFTTLNPVLGTIYRDQNRIIFADIPGLIEGAHTGVGLGHDFLKHIERCFLL
IHLISLDPNDNSDIISAYETIVNELKQYKQSLVNKPIVLVANKIDQIGALENLQILKEHLKDNQYIKVISALTNLHVDAM
LDDVIKIYFDQKKIYEQRLKEHLPVDQILKWASDTPKNKELDKTIKIVKVDDHFFEVFGEYLKYWVHRIPLKTQDNLIRF
NQKLQSINFNQQLLQAGAIAGDSIKIYDITLEFEE

Sequences:

>Translated_435_residues
MAFIDKCKIVLIAGNGGDGIVS*RRETHVPEGGPAGGNGGNGGSI*FVGNHNETSLEFLKYKKIIRAKHGEKGDIKNQHG
ANAEDVFINVPLGTVVYDAITNEILADINIDQQKYLVAQGGLGGHGNTHFKSAFNKAPNLYELGELGENIEVVLELKTIA
DIGIIGLPNAGKSTLISSFTNAKPKTANYMFTTLNPVLGTIYRDQNRIIFADIPGLIEGAHTGVGLGHDFLKHIERCFLL
IHLISLDPNDNSDIISAYETIVNELKQYKQSLVNKPIVLVANKIDQIGALENLQILKEHLKDNQYIKVISALTNLHVDAM
LDDVIKIYFDQKKIYEQRLKEHLPVDQILK*ASDTPKNKELDKTIKIVKVDDHFFEVFGEYLKY*VHRIPLKTQDNLIRF
NQKLQSINFNQQLLQAGAIAGDSIKIYDITLEFEE
>Mature_434_residues
AFIDKCKIVLIAGNGGDGIVS*RRETHVPEGGPAGGNGGNGGSI*FVGNHNETSLEFLKYKKIIRAKHGEKGDIKNQHGA
NAEDVFINVPLGTVVYDAITNEILADINIDQQKYLVAQGGLGGHGNTHFKSAFNKAPNLYELGELGENIEVVLELKTIAD
IGIIGLPNAGKSTLISSFTNAKPKTANYMFTTLNPVLGTIYRDQNRIIFADIPGLIEGAHTGVGLGHDFLKHIERCFLLI
HLISLDPNDNSDIISAYETIVNELKQYKQSLVNKPIVLVANKIDQIGALENLQILKEHLKDNQYIKVISALTNLHVDAML
DDVIKIYFDQKKIYEQRLKEHLPVDQILK*ASDTPKNKELDKTIKIVKVDDHFFEVFGEYLKY*VHRIPLKTQDNLIRFN
QKLQSINFNQQLLQAGAIAGDSIKIYDITLEFEE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=36.4485981308411, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI111955139, Length=287, Percent_Identity=37.9790940766551, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI111955063, Length=202, Percent_Identity=37.1287128712871, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4758796, Length=254, Percent_Identity=30.3149606299213, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58761500, Length=161, Percent_Identity=31.055900621118, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789574, Length=345, Percent_Identity=42.3188405797101, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787454, Length=107, Percent_Identity=35.5140186915888, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=286, Percent_Identity=38.1118881118881, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=357, Percent_Identity=30.812324929972, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=100, Percent_Identity=33, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=161, Percent_Identity=37.888198757764, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319281, Length=214, Percent_Identity=28.5046728971963, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129375, Length=325, Percent_Identity=36.9230769230769, Blast_Score=181, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24585318, Length=287, Percent_Identity=39.7212543554007, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17981711, Length=259, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47801; Mature: 47670

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFIDKCKIVLIAGNGGDGIVSRRETHVPEGGPAGGNGGNGGSIFVGNHNETSLEFLKYK
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
KIIRAKHGEKGDIKNQHGANAEDVFINVPLGTVVYDAITNEILADINIDQQKYLVAQGGL
HHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GGHGNTHFKSAFNKAPNLYELGELGENIEVVLELKTIADIGIIGLPNAGKSTLISSFTNA
CCCCCHHHHHHHHCCCCCEEHHHCCCCEEEEEEEEHHHCCCEEECCCCCHHHHHHHHCCC
KPKTANYMFTTLNPVLGTIYRDQNRIIFADIPGLIEGAHTGVGLGHDFLKHIERCFLLIH
CCCCCCEEEEEHHHHHHHHEECCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LISLDPNDNSDIISAYETIVNELKQYKQSLVNKPIVLVANKIDQIGALENLQILKEHLKD
HEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCC
NQYIKVISALTNLHVDAMLDDVIKIYFDQKKIYEQRLKEHLPVDQILKASDTPKNKELDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
TIKIVKVDDHFFEVFGEYLKYVHRIPLKTQDNLIRFNQKLQSINFNQQLLQAGAIAGDSI
EEEEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCE
KIYDITLEFEE
EEEEEEEEECC
>Mature Secondary Structure 
AFIDKCKIVLIAGNGGDGIVSRRETHVPEGGPAGGNGGNGGSIFVGNHNETSLEFLKYK
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
KIIRAKHGEKGDIKNQHGANAEDVFINVPLGTVVYDAITNEILADINIDQQKYLVAQGGL
HHHHHCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCC
GGHGNTHFKSAFNKAPNLYELGELGENIEVVLELKTIADIGIIGLPNAGKSTLISSFTNA
CCCCCHHHHHHHHCCCCCEEHHHCCCCEEEEEEEEHHHCCCEEECCCCCHHHHHHHHCCC
KPKTANYMFTTLNPVLGTIYRDQNRIIFADIPGLIEGAHTGVGLGHDFLKHIERCFLLIH
CCCCCCEEEEEHHHHHHHHEECCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LISLDPNDNSDIISAYETIVNELKQYKQSLVNKPIVLVANKIDQIGALENLQILKEHLKD
HEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCC
NQYIKVISALTNLHVDAMLDDVIKIYFDQKKIYEQRLKEHLPVDQILKASDTPKNKELDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
TIKIVKVDDHFFEVFGEYLKYVHRIPLKTQDNLIRFNQKLQSINFNQQLLQAGAIAGDSI
EEEEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCE
KIYDITLEFEE
EEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA