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The map label for this gene is pheS [H]

Identifier: 209551838

GI number: 209551838

Start: 4440774

End: 4441856

Strand: Direct

Name: pheS [H]

Synonym: Rleg2_4270

Alternate gene names: 209551838

Gene position: 4440774-4441856 (Clockwise)

Preceding gene: 209551837

Following gene: 209551839

Centisome position: 97.86

GC content: 62.6

Gene sequence:

>1083_bases
ATGTCAGATATCGACCAGCTCAACGCATCGCTGCTCGCCGAAATCGCTGCCGCCAATGACGAGGCGGCCCTGGAAGCGGT
GCGCGTTTCCGCCCTCGGCAAGAAGGGCTCCGTCTCCGAACTGTTGAAGACGCTCGGCGCCATGACGCCGGAAGAACGCC
AGACCCGGGGCGCTGCGATCAACGTTTTGAAGAATGCGGTGACCGAGGCGCTCGCCGCCCGCAAGGCGACGCTCCGCCAA
GAGGCGATCAATGCACGGCTGAAGGCCGAGACGGTCGATGTCAGCCTGCCGGTGCGCTCTTCGCCTGCCGAGCGCGGCCG
CATCCATCCGATCAGCCAGATCGTCGACGAGATCACCGCGATCTTCGCCGATATGGGTTTCTCGATCGCCGAAGGCCCGG
ATATCGAGACCGACTATTACAATTTCACCGCGCTGAATTTCCCCGAAGGCCATCCGGCCCGCGAGATGCACGACACCTTC
TTCTTCCATCCGGACGAGAACGGTGAGCGTAAGGTGCTGCGCACCCATACGTCGCCGGTGCAGGTTCGCACCATGGAGAC
GCAGAAGCCGCCGATCCGCATCATCATTCCCGGCAAGACCTACCGCCAGGACTCGGACGCCACGCATTCGCCGATGTTCC
ACCAGGTCGAAGGCCTCGTCATCGACAAGAAGGCCAATGTCGCCAACATCCGCTGGGTGCTCGAGGAATTCTGCAAGACC
TTCTTCGAGGTCGACAGCGTGACCATGCGTTTCCGCCCGTCGTTTTTCCCTTTCACCGAGCCCTCTTTCGAGGTCGATAT
CCAGTGCGACCGCTCCGGCCCGATCGTCAAGTTCGGCGAAGGCACCGACTGGATGGAGATCCTCGGCTGCGGCATGGTCC
ACCCGAACGTGCTGCGCTACGGCGGGCTCGATCCGGACGAATATCAGGGTTTTGCCTGGGGCATGGGCCTCGACCGCATC
GCCATGCTGAAATACGGCATGCCCGACCTGCGCGATTTCTTCAACGCCGACGTCCGCTGGATGACGCATTACGGCTTCCG
CCCGCTCGACATGCCGACGCTGTTCGGCGGCCTCAGCGCTTGA

Upstream 100 bases:

>100_bases
TTTGGGCTAGCGCGGGTTTTTCTTTCTTTATATTCCTTGCGCCGGCCGGCGCCGCCTGCCTCTCGATCGCCCGCCTGATA
CTGGACGGAAAGAAGTGACA

Downstream 100 bases:

>100_bases
ACGGAGAATTGGGACGATGAAATTCACGCTCTCCTGGCTGAAAGAGCATCTGGAAACGGATGCCGGCCTCGATGAAATCT
GCACGCGCCTCACCCAGATC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSDIDQLNASLLAEIAAANDEAALEAVRVSALGKKGSVSELLKTLGAMTPEERQTRGAAINVLKNAVTEALAARKATLRQ
EAINARLKAETVDVSLPVRSSPAERGRIHPISQIVDEITAIFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTF
FFHPDENGERKVLRTHTSPVQVRTMETQKPPIRIIIPGKTYRQDSDATHSPMFHQVEGLVIDKKANVANIRWVLEEFCKT
FFEVDSVTMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGTDWMEILGCGMVHPNVLRYGGLDPDEYQGFAWGMGLDRI
AMLKYGMPDLRDFFNADVRWMTHYGFRPLDMPTLFGGLSA

Sequences:

>Translated_360_residues
MSDIDQLNASLLAEIAAANDEAALEAVRVSALGKKGSVSELLKTLGAMTPEERQTRGAAINVLKNAVTEALAARKATLRQ
EAINARLKAETVDVSLPVRSSPAERGRIHPISQIVDEITAIFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTF
FFHPDENGERKVLRTHTSPVQVRTMETQKPPIRIIIPGKTYRQDSDATHSPMFHQVEGLVIDKKANVANIRWVLEEFCKT
FFEVDSVTMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGTDWMEILGCGMVHPNVLRYGGLDPDEYQGFAWGMGLDRI
AMLKYGMPDLRDFFNADVRWMTHYGFRPLDMPTLFGGLSA
>Mature_359_residues
SDIDQLNASLLAEIAAANDEAALEAVRVSALGKKGSVSELLKTLGAMTPEERQTRGAAINVLKNAVTEALAARKATLRQE
AINARLKAETVDVSLPVRSSPAERGRIHPISQIVDEITAIFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTFF
FHPDENGERKVLRTHTSPVQVRTMETQKPPIRIIIPGKTYRQDSDATHSPMFHQVEGLVIDKKANVANIRWVLEEFCKTF
FEVDSVTMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGTDWMEILGCGMVHPNVLRYGGLDPDEYQGFAWGMGLDRIA
MLKYGMPDLRDFFNADVRWMTHYGFRPLDMPTLFGGLSA

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=283, Percent_Identity=30.0353356890459, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI5729820, Length=260, Percent_Identity=26.5384615384615, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1788007, Length=344, Percent_Identity=51.453488372093, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI32563657, Length=320, Percent_Identity=30.625, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17508957, Length=320, Percent_Identity=30.625, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32566635, Length=281, Percent_Identity=29.5373665480427, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321087, Length=275, Percent_Identity=30.9090909090909, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6325304, Length=99, Percent_Identity=34.3434343434343, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18858079, Length=280, Percent_Identity=30.7142857142857, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17137424, Length=298, Percent_Identity=23.489932885906, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 40264; Mature: 40133

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIDQLNASLLAEIAAANDEAALEAVRVSALGKKGSVSELLKTLGAMTPEERQTRGAAI
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
NVLKNAVTEALAARKATLRQEAINARLKAETVDVSLPVRSSPAERGRIHPISQIVDEITA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
IFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFHPDENGERKVLRTHTSPV
HHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCEEECCCCCCCCEEEEECCCCE
QVRTMETQKPPIRIIIPGKTYRQDSDATHSPMFHQVEGLVIDKKANVANIRWVLEEFCKT
EEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHH
FFEVDSVTMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGTDWMEILGCGMVHPNVLRY
HHHHHCEEEEECCCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHCCCCCCCHHHC
GGLDPDEYQGFAWGMGLDRIAMLKYGMPDLRDFFNADVRWMTHYGFRPLDMPTLFGGLSA
CCCCHHHCCCEEECCCHHHHHHHHCCCHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
SDIDQLNASLLAEIAAANDEAALEAVRVSALGKKGSVSELLKTLGAMTPEERQTRGAAI
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
NVLKNAVTEALAARKATLRQEAINARLKAETVDVSLPVRSSPAERGRIHPISQIVDEITA
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
IFADMGFSIAEGPDIETDYYNFTALNFPEGHPAREMHDTFFFHPDENGERKVLRTHTSPV
HHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHCCCEEECCCCCCCCEEEEECCCCE
QVRTMETQKPPIRIIIPGKTYRQDSDATHSPMFHQVEGLVIDKKANVANIRWVLEEFCKT
EEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHH
FFEVDSVTMRFRPSFFPFTEPSFEVDIQCDRSGPIVKFGEGTDWMEILGCGMVHPNVLRY
HHHHHCEEEEECCCCCCCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHCCCCCCCHHHC
GGLDPDEYQGFAWGMGLDRIAMLKYGMPDLRDFFNADVRWMTHYGFRPLDMPTLFGGLSA
CCCCHHHCCCEEECCCHHHHHHHHCCCHHHHHHHCCCEEEEECCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA