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The map label for this gene is rhtC [H]

Identifier: 209551765

GI number: 209551765

Start: 4368762

End: 4369394

Strand: Direct

Name: rhtC [H]

Synonym: Rleg2_4194

Alternate gene names: 209551765

Gene position: 4368762-4369394 (Clockwise)

Preceding gene: 209551764

Following gene: 209551767

Centisome position: 96.27

GC content: 64.3

Gene sequence:

>633_bases
ATGTCTTCCGCAGGCGTTTTCATCAGCATCATGGCAGCCCTGGCGGTCGGAGCGATGAGTCCCGGCCCGAGCTTCGTGGT
CGTCTCCAGGATTGCCATTTCGCGGTCGCGGCTGGATGGTCTCGCGGCCGCGCTCGGCATGGGCGCCGGCGGTGTGGTTT
TTGCCGTATTGGCGCTCGCCGGTCTGACAGCGCTGCTGTCGCAGTTCGAATGGCTCTATATCTTGCTGAAGGTCGCAGGC
GGCGCCTATCTCATCTATATCGCCGTCAATATCTGGAGAGGTGTCGGAGAGCCGCTGGAGGTCTCCGACGCCGGCGACAG
CCACCGCGCGCCGAGGCGCAGCTTCATGACTGCGCTGCTGACCCAGCTCAGCAACCCGAAGACCATCATCGTCTATGCCA
GCCTCTTTGCCGCGCTCCTTCCGAGGACGGTGCCGCTCGATCTCATGATTGCGCTACCGCTCGGCGTCTTTGCGGTGGAA
GCGGGATGGTATTCGATCGTGGCGCTGGCCTTTTCGGCCCGCCATCCGCGGCGGCTCTATCTCGCCGCGAAGAGCTGGAT
CGACCGGACTGCCGGTGCTGTCATGGGCGGCCTCGGACTTCGTCTCATTCTGTCGGGCCTCAGCGCGCGCTAG

Upstream 100 bases:

>100_bases
GCATCCAGGTGTCAGACAAGTTCTGATGTTTGCCGCCGCTTACATCGATTCCGATTTAAGGAATAATGCGATACCTTCGA
TCTCAAACGAGGGTTCTTGA

Downstream 100 bases:

>100_bases
AGCAGGATGGCGAAAAGTGTGAGCGGTTATCTCAGTTGGTGTTGCTGCCGTCCGCGGTACCCGGCGTCTTGTCCTTGGCG
GCAAGCTTCTGCCAGGAATT

Product: lysine exporter protein LysE/YggA

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSSAGVFISIMAALAVGAMSPGPSFVVVSRIAISRSRLDGLAAALGMGAGGVVFAVLALAGLTALLSQFEWLYILLKVAG
GAYLIYIAVNIWRGVGEPLEVSDAGDSHRAPRRSFMTALLTQLSNPKTIIVYASLFAALLPRTVPLDLMIALPLGVFAVE
AGWYSIVALAFSARHPRRLYLAAKSWIDRTAGAVMGGLGLRLILSGLSAR

Sequences:

>Translated_210_residues
MSSAGVFISIMAALAVGAMSPGPSFVVVSRIAISRSRLDGLAAALGMGAGGVVFAVLALAGLTALLSQFEWLYILLKVAG
GAYLIYIAVNIWRGVGEPLEVSDAGDSHRAPRRSFMTALLTQLSNPKTIIVYASLFAALLPRTVPLDLMIALPLGVFAVE
AGWYSIVALAFSARHPRRLYLAAKSWIDRTAGAVMGGLGLRLILSGLSAR
>Mature_209_residues
SSAGVFISIMAALAVGAMSPGPSFVVVSRIAISRSRLDGLAAALGMGAGGVVFAVLALAGLTALLSQFEWLYILLKVAGG
AYLIYIAVNIWRGVGEPLEVSDAGDSHRAPRRSFMTALLTQLSNPKTIIVYASLFAALLPRTVPLDLMIALPLGVFAVEA
GWYSIVALAFSARHPRRLYLAAKSWIDRTAGAVMGGLGLRLILSGLSAR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=35.9223300970874, Blast_Score=113, Evalue=8e-27,
Organism=Escherichia coli, GI1786522, Length=193, Percent_Identity=30.0518134715026, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21999; Mature: 21868

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAGVFISIMAALAVGAMSPGPSFVVVSRIAISRSRLDGLAAALGMGAGGVVFAVLALA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GLTALLSQFEWLYILLKVAGGAYLIYIAVNIWRGVGEPLEVSDAGDSHRAPRRSFMTALL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
TQLSNPKTIIVYASLFAALLPRTVPLDLMIALPLGVFAVEAGWYSIVALAFSARHPRRLY
HHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LAAKSWIDRTAGAVMGGLGLRLILSGLSAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSAGVFISIMAALAVGAMSPGPSFVVVSRIAISRSRLDGLAAALGMGAGGVVFAVLALA
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GLTALLSQFEWLYILLKVAGGAYLIYIAVNIWRGVGEPLEVSDAGDSHRAPRRSFMTALL
HHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
TQLSNPKTIIVYASLFAALLPRTVPLDLMIALPLGVFAVEAGWYSIVALAFSARHPRRLY
HHCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LAAKSWIDRTAGAVMGGLGLRLILSGLSAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]