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The map label for this gene is intZ [H]

Identifier: 209551713

GI number: 209551713

Start: 4323143

End: 4324348

Strand: Direct

Name: intZ [H]

Synonym: Rleg2_4142

Alternate gene names: 209551713

Gene position: 4323143-4324348 (Clockwise)

Preceding gene: 209551712

Following gene: 209551714

Centisome position: 95.27

GC content: 63.35

Gene sequence:

>1206_bases
TTGAACAAATTGACCGCGAAGCAGGTCACAAGCATCAAGAAGCCGGGCCGTCATAGCGACGGCGGAAGCCTCTATCTTGT
CGTCGACAAGTCCGGCGCCAAGCGGTGGGTGTTCCTGTATCGCCGCGGCGATCGCCAGCGCGAAATGGGCTTGGGCGGCG
TCGATACTGTATCGCTGGCGAGCGCGCGCGAGCTGGCCGCGGATGCCCGCCGGCTGCTGCAGGCCGGCATTGATCCTATC
GAGGCGAAAAACGCCATCGTCGACGAGATCCCGACCTTCGGCGATTGCGCCGACGATTTCATTGAAACTATGGCCCCGCA
ATTCCGGAACGCGAAGCATATCGCGCAATGGAAAATGACCTTGCAGGAATATGCAAAGCCTCTCCGGCCGAAGGCGGTTG
ACCAGGTCACGACTTCCGACGTGCTGGAAGTCTTGAAACCGATCTGGCTAACGAAGCCGGTCACGGCGTCGCGAGTACGT
GGTCGCGTTGAGCGGGTTCTGGACGCGGCAAAGTCAAAAGGCTACCGGTCAGGTGAAAACCCGGCGCGCTGGCGCGGCCA
CCTGTCAAACCTGCTGCCGAAGCGCAAGAAGCTGACGCGCGGCCATCACGCGGCGCTTCCTTACAAGGACGTGCCTACGT
TCACCGCCGCGCTGCGTGAACGACCGGCCGTCGCGGCGAGGGCTATGGAATTCACAATCCTGACCGTGGCGCGGTCCGGA
GAAACGCGGGGCATGAAGTGGCGCGAAGTCGACCGCGTTGACGAGGTCTGGACGGTGCCGCCCGAGCGGATGAAAGCGTT
CCGCGAACATCGTGTTCCGCTTGCGCCGCGGGCGCTGGCGATCCTCGATGAAATGGCGCTGTTCGGCACCGATCCGGACG
CTTATGTCTTCCCTGGCCAGCAGAAGAACAGGAAGGGCCGACCGCTGTCCGACATGGCAATGGATATGGTGCTGCGGCGG
ATGAAGGTAGACGTCACAGTCCACGGCTTTCGATCCTCCTTCCGCGACTGGTGTGGCGAAGAGAGCACCTTCCCTCGAGA
AATCGCCGAAGCGGCGCTCGCCCACGTGGTCGGCGACGAGACGGAACGCGCCTACCGCCGCGGCGACGCGCTCGAGAAGC
GCCGGCGGCTTATGACGGCTTGGGCGAACTATTGCGAGCCCAAGACCGGCAACGTCATTTCGCTGAAGCGGCGCGCGGGG
GCCTAG

Upstream 100 bases:

>100_bases
TAACTTATTTCCATCGCCCATATTTCGCGTTACCCTTCAGGCAGTTAATATGGCTGCATGTCGTTAGGGTAAAAGTTGGG
GTAGGCCGTTGGCGCTCTCG

Downstream 100 bases:

>100_bases
ATGGATCGACGATCGATATTCGCGCTCGGCCTGCTGGCGCTCGCAGGCTGCCAGTCTGGCGCCGAGCATCAGGCGCAGAT
CGATGCGATGCTTGATGGCA

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MNKLTAKQVTSIKKPGRHSDGGSLYLVVDKSGAKRWVFLYRRGDRQREMGLGGVDTVSLASARELAADARRLLQAGIDPI
EAKNAIVDEIPTFGDCADDFIETMAPQFRNAKHIAQWKMTLQEYAKPLRPKAVDQVTTSDVLEVLKPIWLTKPVTASRVR
GRVERVLDAAKSKGYRSGENPARWRGHLSNLLPKRKKLTRGHHAALPYKDVPTFTAALRERPAVAARAMEFTILTVARSG
ETRGMKWREVDRVDEVWTVPPERMKAFREHRVPLAPRALAILDEMALFGTDPDAYVFPGQQKNRKGRPLSDMAMDMVLRR
MKVDVTVHGFRSSFRDWCGEESTFPREIAEAALAHVVGDETERAYRRGDALEKRRRLMTAWANYCEPKTGNVISLKRRAG
A

Sequences:

>Translated_401_residues
MNKLTAKQVTSIKKPGRHSDGGSLYLVVDKSGAKRWVFLYRRGDRQREMGLGGVDTVSLASARELAADARRLLQAGIDPI
EAKNAIVDEIPTFGDCADDFIETMAPQFRNAKHIAQWKMTLQEYAKPLRPKAVDQVTTSDVLEVLKPIWLTKPVTASRVR
GRVERVLDAAKSKGYRSGENPARWRGHLSNLLPKRKKLTRGHHAALPYKDVPTFTAALRERPAVAARAMEFTILTVARSG
ETRGMKWREVDRVDEVWTVPPERMKAFREHRVPLAPRALAILDEMALFGTDPDAYVFPGQQKNRKGRPLSDMAMDMVLRR
MKVDVTVHGFRSSFRDWCGEESTFPREIAEAALAHVVGDETERAYRRGDALEKRRRLMTAWANYCEPKTGNVISLKRRAG
A
>Mature_401_residues
MNKLTAKQVTSIKKPGRHSDGGSLYLVVDKSGAKRWVFLYRRGDRQREMGLGGVDTVSLASARELAADARRLLQAGIDPI
EAKNAIVDEIPTFGDCADDFIETMAPQFRNAKHIAQWKMTLQEYAKPLRPKAVDQVTTSDVLEVLKPIWLTKPVTASRVR
GRVERVLDAAKSKGYRSGENPARWRGHLSNLLPKRKKLTRGHHAALPYKDVPTFTAALRERPAVAARAMEFTILTVARSG
ETRGMKWREVDRVDEVWTVPPERMKAFREHRVPLAPRALAILDEMALFGTDPDAYVFPGQQKNRKGRPLSDMAMDMVLRR
MKVDVTVHGFRSSFRDWCGEESTFPREIAEAALAHVVGDETERAYRRGDALEKRRRLMTAWANYCEPKTGNVISLKRRAG
A

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=395, Percent_Identity=29.1139240506329, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1788974, Length=390, Percent_Identity=26.6666666666667, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788690, Length=406, Percent_Identity=25.8620689655172, Blast_Score=119, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45256; Mature: 45256

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLTAKQVTSIKKPGRHSDGGSLYLVVDKSGAKRWVFLYRRGDRQREMGLGGVDTVSLA
CCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCHHHCCCCCCCHHHHH
SARELAADARRLLQAGIDPIEAKNAIVDEIPTFGDCADDFIETMAPQFRNAKHIAQWKMT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
LQEYAKPLRPKAVDQVTTSDVLEVLKPIWLTKPVTASRVRGRVERVLDAAKSKGYRSGEN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PARWRGHLSNLLPKRKKLTRGHHAALPYKDVPTFTAALRERPAVAARAMEFTILTVARSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHEEEEEEEECC
ETRGMKWREVDRVDEVWTVPPERMKAFREHRVPLAPRALAILDEMALFGTDPDAYVFPGQ
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCC
QKNRKGRPLSDMAMDMVLRRMKVDVTVHGFRSSFRDWCGEESTFPREIAEAALAHVVGDE
CCCCCCCCHHHHHHHHHHHHHHHCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
TERAYRRGDALEKRRRLMTAWANYCEPKTGNVISLKRRAGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHCCCC
>Mature Secondary Structure
MNKLTAKQVTSIKKPGRHSDGGSLYLVVDKSGAKRWVFLYRRGDRQREMGLGGVDTVSLA
CCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCHHHCCCCCCCHHHHH
SARELAADARRLLQAGIDPIEAKNAIVDEIPTFGDCADDFIETMAPQFRNAKHIAQWKMT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
LQEYAKPLRPKAVDQVTTSDVLEVLKPIWLTKPVTASRVRGRVERVLDAAKSKGYRSGEN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
PARWRGHLSNLLPKRKKLTRGHHAALPYKDVPTFTAALRERPAVAARAMEFTILTVARSG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHEEEEEEEECC
ETRGMKWREVDRVDEVWTVPPERMKAFREHRVPLAPRALAILDEMALFGTDPDAYVFPGQ
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCC
QKNRKGRPLSDMAMDMVLRRMKVDVTVHGFRSSFRDWCGEESTFPREIAEAALAHVVGDE
CCCCCCCCHHHHHHHHHHHHHHHCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
TERAYRRGDALEKRRRLMTAWANYCEPKTGNVISLKRRAGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]