Click here to switch to the map view.

The map label for this gene is ftsK [H]

Identifier: 209551675

GI number: 209551675

Start: 4283978

End: 4286341

Strand: Direct

Name: ftsK [H]

Synonym: Rleg2_4104

Alternate gene names: 209551675

Gene position: 4283978-4286341 (Clockwise)

Preceding gene: 209551674

Following gene: 209551680

Centisome position: 94.4

GC content: 64.89

Gene sequence:

>2364_bases
ATGCGTTTTCCCAGAACCAATTTGACGGACGCCGGGGACTTTTCCAGCGGGATTGAAACGGACCTTCCGGAGGTGATTCC
AGGAGAAAAGCCGGCGGCGCCGATCTGGCAGAGCAATTTTTCCCTCGCGCCGAACGTCCGTTTCACCCGCACGCCGGAAA
CGCTGATCAGCAAGCGGCGGGCGCCGGATGAGCCCGCGCGCGATGATTCGCAGATGGGGCAGCAGGCGATCCGGATCGAG
CCGGTCGCCGTCGATGTGCCCTTCGATATCTATCTGCCGGAGCCGGATGAACTTCCCGCAGCACCGCAGACGATCGAACT
GCAGCCGTCACTCGTTCCCGACGCGCCGGCCGCGCCTGCTTTCCGGGCCACCGCCGAGCTTTCGTCCATTTCGGACTTCG
CCTTCTGGGAAGTCATGGCTTTCGAAGAGGCCGAGCCGGTTCGCGCGCCTGCCGTGATCTCGTTCCCGAAGGCCGAGACT
GCGCCCGAATCGATCACGTCGCTGTTCCGCATCATGGAATGGCGCCCCGGCCGTCCGTCCGTCGCTCCTGTCGCCTCCCG
CCCGGTCTCGCCGGCCGCGACGGTCTCCGCAAAGCCCGCCCCGCGCCCTCCGGCCGCCATATTCCTGGAACGGCCGAGGC
GAACTCCCGTCGAGGCACCGGTTAGACCTGCCCCTCAGCCTGCGCTGACCTCTCCGATTGCGCCCGTGCCTCAGGCGGCG
TCCGCTCTTCCCGTGGCGTCAGCCCCTCAGGCCGCGCCGGCGCCCCAGCGCACGCCGCCGGTCGCCGCGGTTCTGCCGTC
GCCGCGCCTTGCGGCGAGGCCCGAAAAGATCGACGCCTCCGGCTACGAATTCCCGCCGCGTGCCCTCCTGCAGGAGCCGC
CGGAACGCCTTGGCGAGATCATGTCGCAGGAGACGCTGGAACAGAATGCCGGGCTTCTGGAAAGTGTGCTCGAGGATTTC
GGCATCAAGGGCGAGATCATCCATGTCCGCCCGGGCCCTGTTGTCACCCTTTATGAATTCGAACCGGCGCCGGGCGTGAA
GTCGTCGCGCGTTATCGGCCTTGCCGACGATATCGCCCGCTCGATGTCGGCGCTTTCGGCCCGTGTCGCCGTCGTGCCCG
GCCGCAATGTCATCGGCATCGAATTGCCGAACGTCACCCGTGAAACCGTCTATTTCCGCGAGATGATCGAGAGCCAGGAT
TTCGAGAAGAGCGGCTACAAGCTGGCGCTCGGCCTCGGCAAGACCATCGGCGGCGAGCCGGTGATTGCCGAGCTTGCCAA
GATGCCGCATCTGCTCGTCGCCGGCACCACCGGCTCCGGCAAGTCGGTCGCCATCAACACGATGATCCTGTCGCTGCTCT
ATCGTATGACGCCGGAACAGTGCCGGCTGATCATGGTCGATCCGAAGATGCTCGAACTCTCCGTCTATGACGGTATCCCG
CATCTGCTGACGCCGGTCGTCACCGATCCGAAGAAGGCGGTGATGGCGCTCAAATGGGCGGTGCGCGAGATGGAGGAGCG
TTACCGCAAGATGTCGCGCCTCGGGGTGCGCAATATCGACGGTTATAACGACCGCGTGGCGCAGGCCCGCGACAAGGGCG
AGACGATCCATGTCATGGTCCAGGTCGGCTTCGACAAGGGCACCGGCGCTCCGATCGAGGAAAACCAGGCGCTGGACCTG
ACGCCGATGCCCTATATCGTCGTCATCGTCGACGAGATGGCCGACCTGATGATGGTCGCCGGCAAGGAGATCGAAGGCGC
AATCCAGCGCCTGGCCCAAATGGCTCGCGCCGCCGGCATCCATCTGATCATGGCGACACAGCGCCCGTCGGTCGACGTCA
TCACCGGCACGATCAAGGCGAATTTCCCGACCCGCATCTCCTTCCAGGTCACCTCGAAGATCGACAGCCGCACCATCCTT
GGCGAACAGGGTGCCGAGCAGCTGCTCGGCCAGGGCGATATGCTGCATATGCAGGGCGGCGGGCGGATTTCCCGCGTCCA
CGGTCCCTTCGTCTCGGATGTCGAGGTTGAAAAGGTCGTGGCTCACCTGAAGACCCAGGGCCGCCCCGAATATCTCGACA
CCGTCACCGCCGACGAGGAGGAAGAGCCCGAAGAGGAAGAAGCCGGCGCCGTCTTCGACAAGAGCGCCATGGCCTCCGAG
GATGGCAACGAACTCTACGAGCAGGCGGTCAAGGTCGTCATGCGCGACAAGAAGTGCTCGACCTCCTACATCCAGCGCCG
TCTCGGCATCGGCTACAACAGGGCCGCCTCACTGGTCGAACGCATGGAAAAGGAAGGCCTGGTCGGCCCGGCCAATCATG
TCGGCAAGCGCGAGATCGTGTCCGGTCGGGGCGACGGCGAGTAA

Upstream 100 bases:

>100_bases
GGAGCCGTATCGGAACGATACGGTGGGAAGGAACTTATTAACCTTCCTTTTCTATCCCGGTAGGGTCGTAATTTGTTAGG
CATGAGTGAGTAGCGGACGC

Downstream 100 bases:

>100_bases
CGGGAGCCGTCGGTTCCCCGAAGGACGAACGGCCCTGGCCTCAGGCCGGGGCCGCAGACCGGGCGGCGCGTCTGTGCACC
ACCGCGAGCAGGCCTCCGAG

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MRFPRTNLTDAGDFSSGIETDLPEVIPGEKPAAPIWQSNFSLAPNVRFTRTPETLISKRRAPDEPARDDSQMGQQAIRIE
PVAVDVPFDIYLPEPDELPAAPQTIELQPSLVPDAPAAPAFRATAELSSISDFAFWEVMAFEEAEPVRAPAVISFPKAET
APESITSLFRIMEWRPGRPSVAPVASRPVSPAATVSAKPAPRPPAAIFLERPRRTPVEAPVRPAPQPALTSPIAPVPQAA
SALPVASAPQAAPAPQRTPPVAAVLPSPRLAARPEKIDASGYEFPPRALLQEPPERLGEIMSQETLEQNAGLLESVLEDF
GIKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMSALSARVAVVPGRNVIGIELPNVTRETVYFREMIESQD
FEKSGYKLALGLGKTIGGEPVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRMTPEQCRLIMVDPKMLELSVYDGIP
HLLTPVVTDPKKAVMALKWAVREMEERYRKMSRLGVRNIDGYNDRVAQARDKGETIHVMVQVGFDKGTGAPIEENQALDL
TPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTIL
GEQGAEQLLGQGDMLHMQGGGRISRVHGPFVSDVEVEKVVAHLKTQGRPEYLDTVTADEEEEPEEEEAGAVFDKSAMASE
DGNELYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEKEGLVGPANHVGKREIVSGRGDGE

Sequences:

>Translated_787_residues
MRFPRTNLTDAGDFSSGIETDLPEVIPGEKPAAPIWQSNFSLAPNVRFTRTPETLISKRRAPDEPARDDSQMGQQAIRIE
PVAVDVPFDIYLPEPDELPAAPQTIELQPSLVPDAPAAPAFRATAELSSISDFAFWEVMAFEEAEPVRAPAVISFPKAET
APESITSLFRIMEWRPGRPSVAPVASRPVSPAATVSAKPAPRPPAAIFLERPRRTPVEAPVRPAPQPALTSPIAPVPQAA
SALPVASAPQAAPAPQRTPPVAAVLPSPRLAARPEKIDASGYEFPPRALLQEPPERLGEIMSQETLEQNAGLLESVLEDF
GIKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMSALSARVAVVPGRNVIGIELPNVTRETVYFREMIESQD
FEKSGYKLALGLGKTIGGEPVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRMTPEQCRLIMVDPKMLELSVYDGIP
HLLTPVVTDPKKAVMALKWAVREMEERYRKMSRLGVRNIDGYNDRVAQARDKGETIHVMVQVGFDKGTGAPIEENQALDL
TPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTIL
GEQGAEQLLGQGDMLHMQGGGRISRVHGPFVSDVEVEKVVAHLKTQGRPEYLDTVTADEEEEPEEEEAGAVFDKSAMASE
DGNELYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEKEGLVGPANHVGKREIVSGRGDGE
>Mature_787_residues
MRFPRTNLTDAGDFSSGIETDLPEVIPGEKPAAPIWQSNFSLAPNVRFTRTPETLISKRRAPDEPARDDSQMGQQAIRIE
PVAVDVPFDIYLPEPDELPAAPQTIELQPSLVPDAPAAPAFRATAELSSISDFAFWEVMAFEEAEPVRAPAVISFPKAET
APESITSLFRIMEWRPGRPSVAPVASRPVSPAATVSAKPAPRPPAAIFLERPRRTPVEAPVRPAPQPALTSPIAPVPQAA
SALPVASAPQAAPAPQRTPPVAAVLPSPRLAARPEKIDASGYEFPPRALLQEPPERLGEIMSQETLEQNAGLLESVLEDF
GIKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIARSMSALSARVAVVPGRNVIGIELPNVTRETVYFREMIESQD
FEKSGYKLALGLGKTIGGEPVIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRMTPEQCRLIMVDPKMLELSVYDGIP
HLLTPVVTDPKKAVMALKWAVREMEERYRKMSRLGVRNIDGYNDRVAQARDKGETIHVMVQVGFDKGTGAPIEENQALDL
TPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTIL
GEQGAEQLLGQGDMLHMQGGGRISRVHGPFVSDVEVEKVVAHLKTQGRPEYLDTVTADEEEEPEEEEAGAVFDKSAMASE
DGNELYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEKEGLVGPANHVGKREIVSGRGDGE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=501, Percent_Identity=52.0958083832335, Blast_Score=486, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 85404; Mature: 85404

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFPRTNLTDAGDFSSGIETDLPEVIPGEKPAAPIWQSNFSLAPNVRFTRTPETLISKRR
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHCC
APDEPARDDSQMGQQAIRIEPVAVDVPFDIYLPEPDELPAAPQTIELQPSLVPDAPAAPA
CCCCCCCCHHHHCCHHEEEEEEEEECCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCC
FRATAELSSISDFAFWEVMAFEEAEPVRAPAVISFPKAETAPESITSLFRIMEWRPGRPS
HHHHHHHHHCCHHHHHHEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
VAPVASRPVSPAATVSAKPAPRPPAAIFLERPRRTPVEAPVRPAPQPALTSPIAPVPQAA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
SALPVASAPQAAPAPQRTPPVAAVLPSPRLAARPEKIDASGYEFPPRALLQEPPERLGEI
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHH
MSQETLEQNAGLLESVLEDFGIKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIAR
HHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEECHHHHHH
SMSALSARVAVVPGRNVIGIELPNVTRETVYFREMIESQDFEKSGYKLALGLGKTIGGEP
HHHHHHEEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCH
VIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRMTPEQCRLIMVDPKMLELSVYDGIP
HHHHHHHCCEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCH
HLLTPVVTDPKKAVMALKWAVREMEERYRKMSRLGVRNIDGYNDRVAQARDKGETIHVMV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEE
QVGFDKGTGAPIEENQALDLTPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGI
EEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCE
HLIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLLGQGDMLHMQGG
EEEEECCCCCCEEEEEEEEECCCCEEEEEEECCCCCHHECCHHHHHHHHCCCCEEEECCC
GRISRVHGPFVSDVEVEKVVAHLKTQGRPEYLDTVTADEEEEPEEEEAGAVFDKSAMASE
CEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHCCCCCHHHHCCC
DGNELYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEKEGLVGPANHVGKREIV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHC
SGRGDGE
CCCCCCC
>Mature Secondary Structure
MRFPRTNLTDAGDFSSGIETDLPEVIPGEKPAAPIWQSNFSLAPNVRFTRTPETLISKRR
CCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHCC
APDEPARDDSQMGQQAIRIEPVAVDVPFDIYLPEPDELPAAPQTIELQPSLVPDAPAAPA
CCCCCCCCHHHHCCHHEEEEEEEEECCEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCC
FRATAELSSISDFAFWEVMAFEEAEPVRAPAVISFPKAETAPESITSLFRIMEWRPGRPS
HHHHHHHHHCCHHHHHHEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCC
VAPVASRPVSPAATVSAKPAPRPPAAIFLERPRRTPVEAPVRPAPQPALTSPIAPVPQAA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
SALPVASAPQAAPAPQRTPPVAAVLPSPRLAARPEKIDASGYEFPPRALLQEPPERLGEI
CCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHH
MSQETLEQNAGLLESVLEDFGIKGEIIHVRPGPVVTLYEFEPAPGVKSSRVIGLADDIAR
HHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCCCCCEEEECHHHHHH
SMSALSARVAVVPGRNVIGIELPNVTRETVYFREMIESQDFEKSGYKLALGLGKTIGGEP
HHHHHHEEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCH
VIAELAKMPHLLVAGTTGSGKSVAINTMILSLLYRMTPEQCRLIMVDPKMLELSVYDGIP
HHHHHHHCCEEEEEECCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCH
HLLTPVVTDPKKAVMALKWAVREMEERYRKMSRLGVRNIDGYNDRVAQARDKGETIHVMV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCEEEEEE
QVGFDKGTGAPIEENQALDLTPMPYIVVIVDEMADLMMVAGKEIEGAIQRLAQMARAAGI
EEECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCE
HLIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLLGQGDMLHMQGG
EEEEECCCCCCEEEEEEEEECCCCEEEEEEECCCCCHHECCHHHHHHHHCCCCEEEECCC
GRISRVHGPFVSDVEVEKVVAHLKTQGRPEYLDTVTADEEEEPEEEEAGAVFDKSAMASE
CEEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHHCCCCCHHHHCCC
DGNELYEQAVKVVMRDKKCSTSYIQRRLGIGYNRAASLVERMEKEGLVGPANHVGKREIV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHCCCHHHC
SGRGDGE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]