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The map label for this gene is ychM [C]

Identifier: 209551612

GI number: 209551612

Start: 4215157

End: 4216866

Strand: Direct

Name: ychM [C]

Synonym: Rleg2_4041

Alternate gene names: 209551612

Gene position: 4215157-4216866 (Clockwise)

Preceding gene: 209551611

Following gene: 209551613

Centisome position: 92.89

GC content: 63.33

Gene sequence:

>1710_bases
GTGATAGGAAGTCTTCCCATGTTGCGGGGCCTGGCCGGCTTCAACAGAGCCTGGCTCCGCAGTGACATTCCGGCCGGCCT
GTCGATCGCCGCAGTCGGCTTGCCGAGCGCCATCGCCTATCCCGCCATCGCCGGCCTGCCGCCGGAGACCGGCATCTATG
CCAGCATCGTCGCGCCGATTGCCTATGCGATCTTTGGTCCTTCCCGGCTTTTGGTCGTCGGGCCAGACGCTGCGACCATG
ACCGTGCTCGCGGCCGCCATGGGCGCGATCATCGCCGCCGAACCCGCGACGGCAAGTGTCGACAGGGTCGCCATTGCCTC
GGCCCTTGCGCTTGGCGTCGGCGTCTTCTGCATCGCCGCGAAATTGCTGAGGCTCGGCGTTCTCGCGAGCTTCCTCTCCC
GTCCCATCCTGGTGGGCTTCTTCGCCGGCGTGTCGCTGTCGATCCTTGTCGGGCAAATCGGCCGCTTCACGGGGGTGAAG
ATCCAATCGGATGGACTGATCCCGCCACTTGTCGAAATGCTCGCCAAGAGCAGTCTGATCCACTGGCCTTCGCTCGTCCT
CGGCCTCGTGATGTTCGCTTTGTTATGGATCGTCAAAGCCTTCCGGTTCAGAGTTCCGGGTCCCGTTCTGGTGGTTGTCC
TCTCGGTCGTTCTTTCGGCGATCTTCGATTTCCAAGGCCGGGGCATTGCCGTTGTCGGCGATATCCCGAGCGGACTGCCG
AGCCTGTCTCTGCCTGCCTTGCATCAGATGCCTCTCGATAAGATCGTCCTCGGCTCGGCCGCGATCTTTCTGGTCAGTTT
CGGCGCCGGCATCGTCGCGGCAAGAAGCTTCGGGTCGCGAACCGGCGAGGAGGTCGACGCCAATCAGGAATTGGTCGGAC
TTGGCGCCGCCAACATCGCGCCCGCTCTGTTCGGCTCGTTTCCGGTCAGCGTCTCGGATTCCCGAACCGCGATAAACCTG
TCGACGGGCGGCGTTTCCCAGGCGGCGGGACTGGTATCGGCCGCGACGCTGGTTGCCGCCCTTGTGTTCCTTCACAGCGC
GCTGCGAATACTCCCAATCCCCGCGCTCGCGGCAATCCTCGCAACGGCGGCGATCAGCCTCATCGATATTCATGAATTGA
AAAAGATCTGGCGCATCAGCCGCATGGAATTCATTTTTGCGCTGATCGCCATGTGGGGCGCAATCAGCTTCGGTGTTCTT
AACGGCGTCATCGTCGCGGTTGCGGCAACCCTCGTCTACCTCTTGCGGCAGACAATGTTTCCCCGCGACGGTCTTCTCGG
CCGCATCGAGGGACGGCATGGCTTTTTCGATCTCGCCCGCTTTCCGGAAGCGCGCCCCGTCGAGGGTGCTGCCGTCTTCG
CCATTCAAGGCAGCATTCTGTTTTACAACGCCGATTACGTGCGCACGCGGCTGACCTCGGTGGCCAGGGCACTTCCCGCC
GAGACCAGATGCCTCGTGCTCGATGCCGGCGCCGTCACCCATATCGACAGCACCGGCGCAGCCGCACTCGACGCCGTGGC
CGAGATCCTGGCAAAGCGGAATATCGTCTTCGCCATGGCCGATCTCAGCGAAGAAAGCCGCGGCATCCTCGAGCGTGCCG
GGGTCATCGAGGCGATCGGCGCCCACAATCTCTTCAATGGCAGGGAAGAAGCACTGAGAGCGCTGATCGGCACTGTCGGC
GAGGCCGGCAGTGCCGCGTCGGCGGGCTAG

Upstream 100 bases:

>100_bases
CACTAAAGCCATGTCCGCGAAAACCCTGCCTAGGCTTGCGCCGTAAAAACAAGGATCGAGCGGGCACGAGGGCCAACGGC
AATAGATAGGGAGGCTAGGG

Downstream 100 bases:

>100_bases
TGCAATTCTGGCAAAGCTGCTCAGCGGTTTGCGTCCGCAATTGTGTGAAAACAAAGAGGTTTCGCTAAAAGGAGGGAGAG
AAAATGGACGAGAATTACGA

Product: sulfate transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MIGSLPMLRGLAGFNRAWLRSDIPAGLSIAAVGLPSAIAYPAIAGLPPETGIYASIVAPIAYAIFGPSRLLVVGPDAATM
TVLAAAMGAIIAAEPATASVDRVAIASALALGVGVFCIAAKLLRLGVLASFLSRPILVGFFAGVSLSILVGQIGRFTGVK
IQSDGLIPPLVEMLAKSSLIHWPSLVLGLVMFALLWIVKAFRFRVPGPVLVVVLSVVLSAIFDFQGRGIAVVGDIPSGLP
SLSLPALHQMPLDKIVLGSAAIFLVSFGAGIVAARSFGSRTGEEVDANQELVGLGAANIAPALFGSFPVSVSDSRTAINL
STGGVSQAAGLVSAATLVAALVFLHSALRILPIPALAAILATAAISLIDIHELKKIWRISRMEFIFALIAMWGAISFGVL
NGVIVAVAATLVYLLRQTMFPRDGLLGRIEGRHGFFDLARFPEARPVEGAAVFAIQGSILFYNADYVRTRLTSVARALPA
ETRCLVLDAGAVTHIDSTGAAALDAVAEILAKRNIVFAMADLSEESRGILERAGVIEAIGAHNLFNGREEALRALIGTVG
EAGSAASAG

Sequences:

>Translated_569_residues
MIGSLPMLRGLAGFNRAWLRSDIPAGLSIAAVGLPSAIAYPAIAGLPPETGIYASIVAPIAYAIFGPSRLLVVGPDAATM
TVLAAAMGAIIAAEPATASVDRVAIASALALGVGVFCIAAKLLRLGVLASFLSRPILVGFFAGVSLSILVGQIGRFTGVK
IQSDGLIPPLVEMLAKSSLIHWPSLVLGLVMFALLWIVKAFRFRVPGPVLVVVLSVVLSAIFDFQGRGIAVVGDIPSGLP
SLSLPALHQMPLDKIVLGSAAIFLVSFGAGIVAARSFGSRTGEEVDANQELVGLGAANIAPALFGSFPVSVSDSRTAINL
STGGVSQAAGLVSAATLVAALVFLHSALRILPIPALAAILATAAISLIDIHELKKIWRISRMEFIFALIAMWGAISFGVL
NGVIVAVAATLVYLLRQTMFPRDGLLGRIEGRHGFFDLARFPEARPVEGAAVFAIQGSILFYNADYVRTRLTSVARALPA
ETRCLVLDAGAVTHIDSTGAAALDAVAEILAKRNIVFAMADLSEESRGILERAGVIEAIGAHNLFNGREEALRALIGTVG
EAGSAASAG
>Mature_569_residues
MIGSLPMLRGLAGFNRAWLRSDIPAGLSIAAVGLPSAIAYPAIAGLPPETGIYASIVAPIAYAIFGPSRLLVVGPDAATM
TVLAAAMGAIIAAEPATASVDRVAIASALALGVGVFCIAAKLLRLGVLASFLSRPILVGFFAGVSLSILVGQIGRFTGVK
IQSDGLIPPLVEMLAKSSLIHWPSLVLGLVMFALLWIVKAFRFRVPGPVLVVVLSVVLSAIFDFQGRGIAVVGDIPSGLP
SLSLPALHQMPLDKIVLGSAAIFLVSFGAGIVAARSFGSRTGEEVDANQELVGLGAANIAPALFGSFPVSVSDSRTAINL
STGGVSQAAGLVSAATLVAALVFLHSALRILPIPALAAILATAAISLIDIHELKKIWRISRMEFIFALIAMWGAISFGVL
NGVIVAVAATLVYLLRQTMFPRDGLLGRIEGRHGFFDLARFPEARPVEGAAVFAIQGSILFYNADYVRTRLTSVARALPA
ETRCLVLDAGAVTHIDSTGAAALDAVAEILAKRNIVFAMADLSEESRGILERAGVIEAIGAHNLFNGREEALRALIGTVG
EAGSAASAG

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721259, Length=494, Percent_Identity=29.3522267206478, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI94721257, Length=494, Percent_Identity=29.3522267206478, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI94721255, Length=494, Percent_Identity=29.3522267206478, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI94721253, Length=494, Percent_Identity=29.3522267206478, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI45827800, Length=512, Percent_Identity=27.5390625, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI39752683, Length=512, Percent_Identity=27.5390625, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI269784651, Length=509, Percent_Identity=26.3261296660118, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI4557535, Length=491, Percent_Identity=26.8839103869654, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI47131207, Length=520, Percent_Identity=28.0769230769231, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI20336272, Length=520, Percent_Identity=28.0769230769231, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI45827802, Length=450, Percent_Identity=28.2222222222222, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4505697, Length=499, Percent_Identity=23.8476953907816, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI100913030, Length=517, Percent_Identity=24.1779497098646, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI65506789, Length=569, Percent_Identity=26.1862917398945, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI16418413, Length=503, Percent_Identity=22.2664015904573, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI217272867, Length=503, Percent_Identity=22.2664015904573, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI262206105, Length=364, Percent_Identity=26.6483516483516, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI262206075, Length=364, Percent_Identity=26.6483516483516, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI262206069, Length=364, Percent_Identity=26.6483516483516, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI262206063, Length=364, Percent_Identity=26.6483516483516, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI20336282, Length=563, Percent_Identity=21.6696269982238, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI16306483, Length=563, Percent_Identity=21.6696269982238, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI16418457, Length=505, Percent_Identity=21.980198019802, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI301601599, Length=505, Percent_Identity=21.980198019802, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI45827804, Length=263, Percent_Identity=25.8555133079848, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI301601602, Length=221, Percent_Identity=25.3393665158371, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87081859, Length=423, Percent_Identity=25.2955082742317, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI86564196, Length=617, Percent_Identity=22.0421393841167, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17566848, Length=563, Percent_Identity=26.4653641207815, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17562578, Length=624, Percent_Identity=23.7179487179487, Blast_Score=152, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17551690, Length=589, Percent_Identity=23.4295415959253, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI86565215, Length=566, Percent_Identity=23.8515901060071, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI86564876, Length=666, Percent_Identity=21.1711711711712, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI193203292, Length=502, Percent_Identity=25.2988047808765, Blast_Score=125, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI86565209, Length=242, Percent_Identity=26.0330578512397, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86565211, Length=242, Percent_Identity=26.0330578512397, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86565213, Length=248, Percent_Identity=24.5967741935484, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=580, Percent_Identity=22.9310344827586, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6323121, Length=472, Percent_Identity=24.5762711864407, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6319771, Length=471, Percent_Identity=23.9915074309979, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI19922482, Length=565, Percent_Identity=26.0176991150442, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI85815873, Length=536, Percent_Identity=25.3731343283582, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24649801, Length=574, Percent_Identity=24.5644599303136, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24651449, Length=562, Percent_Identity=22.9537366548043, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24666186, Length=402, Percent_Identity=26.3681592039801, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24663084, Length=552, Percent_Identity=24.8188405797101, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357695, Length=552, Percent_Identity=24.8188405797101, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21358229, Length=465, Percent_Identity=25.5913978494624, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355087, Length=567, Percent_Identity=22.5749559082892, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647160, Length=562, Percent_Identity=22.4199288256228, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21358633, Length=544, Percent_Identity=22.0588235294118, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 58767; Mature: 58767

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGSLPMLRGLAGFNRAWLRSDIPAGLSIAAVGLPSAIAYPAIAGLPPETGIYASIVAPI
CCCCCHHHHHHHCCCHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHH
AYAIFGPSRLLVVGPDAATMTVLAAAMGAIIAAEPATASVDRVAIASALALGVGVFCIAA
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KLLRLGVLASFLSRPILVGFFAGVSLSILVGQIGRFTGVKIQSDGLIPPLVEMLAKSSLI
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCC
HWPSLVLGLVMFALLWIVKAFRFRVPGPVLVVVLSVVLSAIFDFQGRGIAVVGDIPSGLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
SLSLPALHQMPLDKIVLGSAAIFLVSFGAGIVAARSFGSRTGEEVDANQELVGLGAANIA
CCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEECCCHHHH
PALFGSFPVSVSDSRTAINLSTGGVSQAAGLVSAATLVAALVFLHSALRILPIPALAAIL
HHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATAAISLIDIHELKKIWRISRMEFIFALIAMWGAISFGVLNGVIVAVAATLVYLLRQTMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRDGLLGRIEGRHGFFDLARFPEARPVEGAAVFAIQGSILFYNADYVRTRLTSVARALPA
CCCCCCEEECCCCCCHHHHHCCCCCCCCCEEEEEEECEEEEEECHHHHHHHHHHHHHCCC
ETRCLVLDAGAVTHIDSTGAAALDAVAEILAKRNIVFAMADLSEESRGILERAGVIEAIG
CCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHC
AHNLFNGREEALRALIGTVGEAGSAASAG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIGSLPMLRGLAGFNRAWLRSDIPAGLSIAAVGLPSAIAYPAIAGLPPETGIYASIVAPI
CCCCCHHHHHHHCCCHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHH
AYAIFGPSRLLVVGPDAATMTVLAAAMGAIIAAEPATASVDRVAIASALALGVGVFCIAA
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KLLRLGVLASFLSRPILVGFFAGVSLSILVGQIGRFTGVKIQSDGLIPPLVEMLAKSSLI
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCC
HWPSLVLGLVMFALLWIVKAFRFRVPGPVLVVVLSVVLSAIFDFQGRGIAVVGDIPSGLP
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
SLSLPALHQMPLDKIVLGSAAIFLVSFGAGIVAARSFGSRTGEEVDANQELVGLGAANIA
CCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEECCCHHHH
PALFGSFPVSVSDSRTAINLSTGGVSQAAGLVSAATLVAALVFLHSALRILPIPALAAIL
HHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATAAISLIDIHELKKIWRISRMEFIFALIAMWGAISFGVLNGVIVAVAATLVYLLRQTMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRDGLLGRIEGRHGFFDLARFPEARPVEGAAVFAIQGSILFYNADYVRTRLTSVARALPA
CCCCCCEEECCCCCCHHHHHCCCCCCCCCEEEEEEECEEEEEECHHHHHHHHHHHHHCCC
ETRCLVLDAGAVTHIDSTGAAALDAVAEILAKRNIVFAMADLSEESRGILERAGVIEAIG
CCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHC
AHNLFNGREEALRALIGTVGEAGSAASAG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]