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The map label for this gene is yiaV [H]

Identifier: 209551611

GI number: 209551611

Start: 4213905

End: 4215062

Strand: Direct

Name: yiaV [H]

Synonym: Rleg2_4040

Alternate gene names: 209551611

Gene position: 4213905-4215062 (Clockwise)

Preceding gene: 209551610

Following gene: 209551612

Centisome position: 92.86

GC content: 60.97

Gene sequence:

>1158_bases
ATGGATCTGCTCCTGATACTCACCTACGCCGCGATCTGTTGGGCAATCTTCAAAATATTCAGGATCCCGGTAAACCAGTG
GACGCTCGCAACCGCCGTCCTTGGGGGGATCTTCCTTCTGTCTACCCTCCTGCTCCTGATGAGCTACAACCATCCCTATT
CGAGCGACGGCCGCATCTATTTCACCTCCGCGCCGGTTATTCCCGTCGTCGGAGGCCAGGTGGTCGAGGTGCCGGTGACA
CCGAATGCGCCTCTCAAAAAGGGCGATATCCTCTTTCGCATCGATCCGCGGCCCTATCAGTTTACCGTCGATCAAAAGAA
AGCGGCGCTCGCCGAGGCTGAGCAGTCCGTCCTGCAGTTGAAAGCCGCCATGGATGCCGCCGAATCAGGGGTCACGGGCG
CCGAGGCCACGAGGGACAGGTCACAGCAGGCCTTCGAAAAGTTCCAGCAGACGAACGAGAATGCGAAGTCGAGCGGCAAG
GGTGCGGCCTTTTCCGAACTCGAGGTCGAAAACCGACGCGGCATCTACCTGACATCGGAGGCTGCGGTCGCCACGGCCCG
CGCGCAAGCGGTGCAGGCAAAGCTTGCCTATGAGTCCGAGATCGACGGAACCAACCCGACAGTCGCAAGGCTGCAAGCGG
AATTGCACAATGCCGAGTACGAACTCGACCAGACGGTTGTGCGGGCGCCGACCGATGGCTACGTCACGCAGGTCTTCCTG
CGCCCTGGAATGATGGCCAACCCGCTACCCCTGCGGCCGGTCATGGTGTTCATCGACAGTCAGGACCGCATGCTGGCGGC
AGCCTTCATCCAGAACTCGCTGCAGCGCGTCCGTGTCGGCGATGAGGCGGAGGTCTCTTTCAAAGCCGTGCCCGGCAAGA
TTTTCAAGGCGCGGGTTCAGGAGGTCATCGATGTGATGGCCCAGGGCCAACTGCAGCCGAGCGGTGCGCTGATCGATCCG
CAATCGCCCGAGCGCGTCTCGCCGGGACAGACGCTGGCTCGGATCGAGTTGCTCGAAAGTACCGACGAATATCAACTGCC
CGGCGGCGTCGTCGCCGAGGTCGCGGTCTACACCCATCATTGGCACCATGTCGCTGTCCTTCGCAAGGTGCTGCTGCGGA
TGAGCAGCTGGATGAACTTCGTGTTCCTCGAACACTAA

Upstream 100 bases:

>100_bases
GAAAATTATCGGCGGAAGTTGAGGCGAATGCGGAAATCGCTCGTCTCCATGCAAGAATCGCCGAACTCGAAGCAAAGACG
CCGGAGAAGGAGAACGCCTG

Downstream 100 bases:

>100_bases
AGCCATGTCCGCGAAAACCCTGCCTAGGCTTGCGCCGTAAAAACAAGGATCGAGCGGGCACGAGGGCCAACGGCAATAGA
TAGGGAGGCTAGGGGTGATA

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MDLLLILTYAAICWAIFKIFRIPVNQWTLATAVLGGIFLLSTLLLLMSYNHPYSSDGRIYFTSAPVIPVVGGQVVEVPVT
PNAPLKKGDILFRIDPRPYQFTVDQKKAALAEAEQSVLQLKAAMDAAESGVTGAEATRDRSQQAFEKFQQTNENAKSSGK
GAAFSELEVENRRGIYLTSEAAVATARAQAVQAKLAYESEIDGTNPTVARLQAELHNAEYELDQTVVRAPTDGYVTQVFL
RPGMMANPLPLRPVMVFIDSQDRMLAAAFIQNSLQRVRVGDEAEVSFKAVPGKIFKARVQEVIDVMAQGQLQPSGALIDP
QSPERVSPGQTLARIELLESTDEYQLPGGVVAEVAVYTHHWHHVAVLRKVLLRMSSWMNFVFLEH

Sequences:

>Translated_385_residues
MDLLLILTYAAICWAIFKIFRIPVNQWTLATAVLGGIFLLSTLLLLMSYNHPYSSDGRIYFTSAPVIPVVGGQVVEVPVT
PNAPLKKGDILFRIDPRPYQFTVDQKKAALAEAEQSVLQLKAAMDAAESGVTGAEATRDRSQQAFEKFQQTNENAKSSGK
GAAFSELEVENRRGIYLTSEAAVATARAQAVQAKLAYESEIDGTNPTVARLQAELHNAEYELDQTVVRAPTDGYVTQVFL
RPGMMANPLPLRPVMVFIDSQDRMLAAAFIQNSLQRVRVGDEAEVSFKAVPGKIFKARVQEVIDVMAQGQLQPSGALIDP
QSPERVSPGQTLARIELLESTDEYQLPGGVVAEVAVYTHHWHHVAVLRKVLLRMSSWMNFVFLEH
>Mature_385_residues
MDLLLILTYAAICWAIFKIFRIPVNQWTLATAVLGGIFLLSTLLLLMSYNHPYSSDGRIYFTSAPVIPVVGGQVVEVPVT
PNAPLKKGDILFRIDPRPYQFTVDQKKAALAEAEQSVLQLKAAMDAAESGVTGAEATRDRSQQAFEKFQQTNENAKSSGK
GAAFSELEVENRRGIYLTSEAAVATARAQAVQAKLAYESEIDGTNPTVARLQAELHNAEYELDQTVVRAPTDGYVTQVFL
RPGMMANPLPLRPVMVFIDSQDRMLAAAFIQNSLQRVRVGDEAEVSFKAVPGKIFKARVQEVIDVMAQGQLQPSGALIDP
QSPERVSPGQTLARIELLESTDEYQLPGGVVAEVAVYTHHWHHVAVLRKVLLRMSSWMNFVFLEH

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=387, Percent_Identity=45.4780361757106, Blast_Score=337, Evalue=6e-94,
Organism=Escherichia coli, GI1790024, Length=387, Percent_Identity=43.9276485788114, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1790519, Length=267, Percent_Identity=28.4644194756554, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42439; Mature: 42439

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLILTYAAICWAIFKIFRIPVNQWTLATAVLGGIFLLSTLLLLMSYNHPYSSDGRIY
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
FTSAPVIPVVGGQVVEVPVTPNAPLKKGDILFRIDPRPYQFTVDQKKAALAEAEQSVLQL
EECCCEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHH
KAAMDAAESGVTGAEATRDRSQQAFEKFQQTNENAKSSGKGAAFSELEVENRRGIYLTSE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEECC
AAVATARAQAVQAKLAYESEIDGTNPTVARLQAELHNAEYELDQTVVRAPTDGYVTQVFL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHEECCCCCCEEEEEE
RPGMMANPLPLRPVMVFIDSQDRMLAAAFIQNSLQRVRVGDEAEVSFKAVPGKIFKARVQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
EVIDVMAQGQLQPSGALIDPQSPERVSPGQTLARIELLESTDEYQLPGGVVAEVAVYTHH
HHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
WHHVAVLRKVLLRMSSWMNFVFLEH
HHHHHHHHHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MDLLLILTYAAICWAIFKIFRIPVNQWTLATAVLGGIFLLSTLLLLMSYNHPYSSDGRIY
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
FTSAPVIPVVGGQVVEVPVTPNAPLKKGDILFRIDPRPYQFTVDQKKAALAEAEQSVLQL
EECCCEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHHH
KAAMDAAESGVTGAEATRDRSQQAFEKFQQTNENAKSSGKGAAFSELEVENRRGIYLTSE
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEECC
AAVATARAQAVQAKLAYESEIDGTNPTVARLQAELHNAEYELDQTVVRAPTDGYVTQVFL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHEECCCCCCEEEEEE
RPGMMANPLPLRPVMVFIDSQDRMLAAAFIQNSLQRVRVGDEAEVSFKAVPGKIFKARVQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
EVIDVMAQGQLQPSGALIDPQSPERVSPGQTLARIELLESTDEYQLPGGVVAEVAVYTHH
HHHHHHHCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
WHHVAVLRKVLLRMSSWMNFVFLEH
HHHHHHHHHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]