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The map label for this gene is prtE [H]

Identifier: 209551566

GI number: 209551566

Start: 4159037

End: 4160386

Strand: Reverse

Name: prtE [H]

Synonym: Rleg2_3995

Alternate gene names: 209551566

Gene position: 4160386-4159037 (Counterclockwise)

Preceding gene: 209551567

Following gene: 209551565

Centisome position: 91.68

GC content: 59.78

Gene sequence:

>1350_bases
ATGGCACGGAAACAACAGGAGACCGCCGGTCCGGTGCAGCTCGAATGGTACAGCGATGTACCGCGCTCGATCCGGATGCA
CAGCATCGTCGGCCTGACGGTTCTCTTCACTTCATTCGGAGGGTTCGGCTTTTGGGCCGCAACGGCGCCGCTTGCCTCGG
CTGTCATCGCCCAGGGAAGTTTCGTTGCGACCGGCAACAACAAGATTGTCCAGCATCTGGAGGGCGGCATCATCAAGGAG
ATGCGCGTCAGCGAGGGTGATACCGTGAGGGAAGGCGATATTTTGCTGACCCTCGATCCAACCGCCTCTCGCTCGAATGA
GCGGATGCTGCAGCTTCGCCGCCTGCGCCTGGAAGCCGTCGTCACAAGGCTGCGCGCCGAGGCGCAGGGTCTGCAGGAAT
TCCAGCTTCCCGCTATTGTGACGAAAGAGGCGGGCGATCCGGACATCAATGCGATCATCCAGAGCCAGAACATCGTCTTC
CACAGCAAGCAGATCAAGCTCGAAGAGCAGCTCAATCTGATCGAGAAAAACATCCAATCGCTGGAATACCGTTTCGCCGG
TTATACCGGCCAAAAGGAATCCTTCGAAAGGCAGCTATCGCTGCTGACAGAGGAACGCGACTCCAAGGCCCGGCTGGTCA
AGGTCGGCTATATGCGCAAGACGGATCTCTTGGCGATCGAGCGGGCGATCGCCGATGCCATGGGCGACATTGCGCGCCTG
AACGGCGAGATCAACGAGAGCGAGGCAGAGATCGCCAAATTCCGCCAGGAAGCCGTCATCGCCGTCAACTCCAACAAGCA
GGCGGCACTCGACGCGCTCGAGACCGCCGAATCCGATCTCGACAGCGTACGCGAACAGATGCGCGAGGCTGCAGGCGTGC
TCGAGCGCACCACCATCCGTTCACCGGTGTCGGGAACCGTCGTACGCTCCTATTTTCATACCGCCGGCGGCGTCATCACC
ACGGGCAAGCCGATCATGGAAATCCTGCCGGCGCATGTGCCGCTGATCCTGGAGGCGCAGGTGCTGCGAACCTCCATCGA
CCAGCTGCGCGAGGGAGAAATGGCATCGGTCAGGCTGACGGCGCTCAACCGGCGGACGACGCCGGTTCTAGAGGGCAAGG
TCTTTTACGTCTCAGCCGATTCGATCGAGGAGAATGCGGGCCTCTCGGTCAAGGACGTCTATATCGTTCGCGTCGCAATA
CCGGATTCCGAGATTGCGCGGGTGCATAATTTCCATCCGGTTCCAGGCATGCCGGCCGAAGTGCTGATCCAGACGTCGGA
ACGCACCTTTTTCGAATATATCAGCAAACCAATCACCGACAGCATGTCCCGGGCATTCAAGGAACGCTGA

Upstream 100 bases:

>100_bases
ACTGTCGCCATGTTCGGGGAGCGGATCGAGGTGCTGCGGGCGCTTTCGAAGAATAACAGCAATAACGGTCAACAAGCACC
GCGCATCGAAGGGTGAAGCT

Downstream 100 bases:

>100_bases
GCGGCCCGGTAAACGACGGCGGTCCGCGAGGACGAGGGATTTGTCCGGGTTCTGATATGATGTCGGTAATCTATCATCCC
TTCGGGATGGATCGTTCCCT

Product: type I secretion membrane fusion protein, HlyD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MARKQQETAGPVQLEWYSDVPRSIRMHSIVGLTVLFTSFGGFGFWAATAPLASAVIAQGSFVATGNNKIVQHLEGGIIKE
MRVSEGDTVREGDILLTLDPTASRSNERMLQLRRLRLEAVVTRLRAEAQGLQEFQLPAIVTKEAGDPDINAIIQSQNIVF
HSKQIKLEEQLNLIEKNIQSLEYRFAGYTGQKESFERQLSLLTEERDSKARLVKVGYMRKTDLLAIERAIADAMGDIARL
NGEINESEAEIAKFRQEAVIAVNSNKQAALDALETAESDLDSVREQMREAAGVLERTTIRSPVSGTVVRSYFHTAGGVIT
TGKPIMEILPAHVPLILEAQVLRTSIDQLREGEMASVRLTALNRRTTPVLEGKVFYVSADSIEENAGLSVKDVYIVRVAI
PDSEIARVHNFHPVPGMPAEVLIQTSERTFFEYISKPITDSMSRAFKER

Sequences:

>Translated_449_residues
MARKQQETAGPVQLEWYSDVPRSIRMHSIVGLTVLFTSFGGFGFWAATAPLASAVIAQGSFVATGNNKIVQHLEGGIIKE
MRVSEGDTVREGDILLTLDPTASRSNERMLQLRRLRLEAVVTRLRAEAQGLQEFQLPAIVTKEAGDPDINAIIQSQNIVF
HSKQIKLEEQLNLIEKNIQSLEYRFAGYTGQKESFERQLSLLTEERDSKARLVKVGYMRKTDLLAIERAIADAMGDIARL
NGEINESEAEIAKFRQEAVIAVNSNKQAALDALETAESDLDSVREQMREAAGVLERTTIRSPVSGTVVRSYFHTAGGVIT
TGKPIMEILPAHVPLILEAQVLRTSIDQLREGEMASVRLTALNRRTTPVLEGKVFYVSADSIEENAGLSVKDVYIVRVAI
PDSEIARVHNFHPVPGMPAEVLIQTSERTFFEYISKPITDSMSRAFKER
>Mature_448_residues
ARKQQETAGPVQLEWYSDVPRSIRMHSIVGLTVLFTSFGGFGFWAATAPLASAVIAQGSFVATGNNKIVQHLEGGIIKEM
RVSEGDTVREGDILLTLDPTASRSNERMLQLRRLRLEAVVTRLRAEAQGLQEFQLPAIVTKEAGDPDINAIIQSQNIVFH
SKQIKLEEQLNLIEKNIQSLEYRFAGYTGQKESFERQLSLLTEERDSKARLVKVGYMRKTDLLAIERAIADAMGDIARLN
GEINESEAEIAKFRQEAVIAVNSNKQAALDALETAESDLDSVREQMREAAGVLERTTIRSPVSGTVVRSYFHTAGGVITT
GKPIMEILPAHVPLILEAQVLRTSIDQLREGEMASVRLTALNRRTTPVLEGKVFYVSADSIEENAGLSVKDVYIVRVAIP
DSEIARVHNFHPVPGMPAEVLIQTSERTFFEYISKPITDSMSRAFKER

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 49820; Mature: 49688

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKQQETAGPVQLEWYSDVPRSIRMHSIVGLTVLFTSFGGFGFWAATAPLASAVIAQGS
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
FVATGNNKIVQHLEGGIIKEMRVSEGDTVREGDILLTLDPTASRSNERMLQLRRLRLEAV
EEEECCCHHHHHHCCCHHHHHCCCCCCCEECCCEEEEECCCCCCCHHHHHHHHHHHHHHH
VTRLRAEAQGLQEFQLPAIVTKEAGDPDINAIIQSQNIVFHSKQIKLEEQLNLIEKNIQS
HHHHHHHHHCHHHHCCCEEEECCCCCCCHHEEEECCCEEEECHHCCHHHHHHHHHHHHHH
LEYRFAGYTGQKESFERQLSLLTEERDSKARLVKVGYMRKTDLLAIERAIADAMGDIARL
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
NGEINESEAEIAKFRQEAVIAVNSNKQAALDALETAESDLDSVREQMREAAGVLERTTIR
CCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPVSGTVVRSYFHTAGGVITTGKPIMEILPAHVPLILEAQVLRTSIDQLREGEMASVRLT
CCCCHHHHHHHHHHCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
ALNRRTTPVLEGKVFYVSADSIEENAGLSVKDVYIVRVAIPDSEIARVHNFHPVPGMPAE
EECCCCCCEECCEEEEEECCCCCCCCCCEEEEEEEEEEECCCHHHHHHCCCCCCCCCCHH
VLIQTSERTFFEYISKPITDSMSRAFKER
HEEECCHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure 
ARKQQETAGPVQLEWYSDVPRSIRMHSIVGLTVLFTSFGGFGFWAATAPLASAVIAQGS
CCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
FVATGNNKIVQHLEGGIIKEMRVSEGDTVREGDILLTLDPTASRSNERMLQLRRLRLEAV
EEEECCCHHHHHHCCCHHHHHCCCCCCCEECCCEEEEECCCCCCCHHHHHHHHHHHHHHH
VTRLRAEAQGLQEFQLPAIVTKEAGDPDINAIIQSQNIVFHSKQIKLEEQLNLIEKNIQS
HHHHHHHHHCHHHHCCCEEEECCCCCCCHHEEEECCCEEEECHHCCHHHHHHHHHHHHHH
LEYRFAGYTGQKESFERQLSLLTEERDSKARLVKVGYMRKTDLLAIERAIADAMGDIARL
HHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
NGEINESEAEIAKFRQEAVIAVNSNKQAALDALETAESDLDSVREQMREAAGVLERTTIR
CCCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SPVSGTVVRSYFHTAGGVITTGKPIMEILPAHVPLILEAQVLRTSIDQLREGEMASVRLT
CCCCHHHHHHHHHHCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
ALNRRTTPVLEGKVFYVSADSIEENAGLSVKDVYIVRVAIPDSEIARVHNFHPVPGMPAE
EECCCCCCEECCEEEEEECCCCCCCCCCEEEEEEEEEEECCCHHHHHHCCCCCCCCCCHH
VLIQTSERTFFEYISKPITDSMSRAFKER
HEEECCHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]