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The map label for this gene is actR [H]

Identifier: 209551560

GI number: 209551560

Start: 4141527

End: 4142105

Strand: Reverse

Name: actR [H]

Synonym: Rleg2_3989

Alternate gene names: 209551560

Gene position: 4142105-4141527 (Counterclockwise)

Preceding gene: 209551561

Following gene: 209551558

Centisome position: 91.28

GC content: 63.73

Gene sequence:

>579_bases
ATGACAGAACAAACTCACGAAAATTTCGCCGCTGGGGATGAAGACCATATCGGTCCCGACGCCAGCCTGCTGATCGTCGA
CGACGACGGGCCGTTCCTGCGCCGGCTGGCCCGGGCGATGGAGACACGCGGTTTCCAGGTGGAAACGGCCGAATCAGTGG
CGGAGGGCGTGGCGAAATCGAAAGGCAGGCCGCCGAAATATGCGGTTGTCGACCTCCGGCTCGGCGACGGCAATGGGCTC
GATGTCATCGAAGCGATCCGCCAGCGGCGCGACGACACCAGGATCATCGTGCTGACCGGCTACGGCAATATCGCAACCGC
AGTGACCGCCGTAAAACTCGGCGCCGTCGATTACCTGGCAAAGCCCGCGGATGCCGACGACGTCTTTTCGGCGCTGACGC
AGAGGCCGGGCGAAAAGGCCGAGCTTCCCGAGAACCCGATGTCGGCCGACCGGGTGCGCTGGGAACATATCCAGCGGGTC
TATGAAATGTGCGAGCGCAACGTCTCGGAAACGGCGCGCCGGCTCAATATGCACCGGCGCACGCTGCAGCGCATCCTCGC
CAAACGCGCGCCGAAATAG

Upstream 100 bases:

>100_bases
GCATGCTGATCGACGCAAATTCGACAAAGTGACTTTGTCGGCATAAGTAGGATATAAGCGGTTGACGCAGATCGGGCGTT
CAAGCGCCAGGGCCAAGACG

Downstream 100 bases:

>100_bases
CCAAGACATCCGTCAGACATCATCGACGGTGAAGGGCTTTCCGTTCGCCCATTCGGCCATCATCAGCCGTTGCGCGGCGG
CGCGCGAGAAATTGAGCGTG

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 191

Protein sequence:

>192_residues
MTEQTHENFAAGDEDHIGPDASLLIVDDDGPFLRRLARAMETRGFQVETAESVAEGVAKSKGRPPKYAVVDLRLGDGNGL
DVIEAIRQRRDDTRIIVLTGYGNIATAVTAVKLGAVDYLAKPADADDVFSALTQRPGEKAELPENPMSADRVRWEHIQRV
YEMCERNVSETARRLNMHRRTLQRILAKRAPK

Sequences:

>Translated_192_residues
MTEQTHENFAAGDEDHIGPDASLLIVDDDGPFLRRLARAMETRGFQVETAESVAEGVAKSKGRPPKYAVVDLRLGDGNGL
DVIEAIRQRRDDTRIIVLTGYGNIATAVTAVKLGAVDYLAKPADADDVFSALTQRPGEKAELPENPMSADRVRWEHIQRV
YEMCERNVSETARRLNMHRRTLQRILAKRAPK
>Mature_191_residues
TEQTHENFAAGDEDHIGPDASLLIVDDDGPFLRRLARAMETRGFQVETAESVAEGVAKSKGRPPKYAVVDLRLGDGNGLD
VIEAIRQRRDDTRIIVLTGYGNIATAVTAVKLGAVDYLAKPADADDVFSALTQRPGEKAELPENPMSADRVRWEHIQRVY
EMCERNVSETARRLNMHRRTLQRILAKRAPK

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=112, Percent_Identity=33.9285714285714, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=30.0884955752212, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21378; Mature: 21247

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTHENFAAGDEDHIGPDASLLIVDDDGPFLRRLARAMETRGFQVETAESVAEGVAKS
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHC
KGRPPKYAVVDLRLGDGNGLDVIEAIRQRRDDTRIIVLTGYGNIATAVTAVKLGAVDYLA
CCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHC
KPADADDVFSALTQRPGEKAELPENPMSADRVRWEHIQRVYEMCERNVSETARRLNMHRR
CCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TLQRILAKRAPK
HHHHHHHHCCCC
>Mature Secondary Structure 
TEQTHENFAAGDEDHIGPDASLLIVDDDGPFLRRLARAMETRGFQVETAESVAEGVAKS
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHC
KGRPPKYAVVDLRLGDGNGLDVIEAIRQRRDDTRIIVLTGYGNIATAVTAVKLGAVDYLA
CCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHC
KPADADDVFSALTQRPGEKAELPENPMSADRVRWEHIQRVYEMCERNVSETARRLNMHRR
CCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
TLQRILAKRAPK
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]