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The map label for this gene is coaA [H]

Identifier: 209551544

GI number: 209551544

Start: 4127696

End: 4128691

Strand: Reverse

Name: coaA [H]

Synonym: Rleg2_3973

Alternate gene names: 209551544

Gene position: 4128691-4127696 (Counterclockwise)

Preceding gene: 209551545

Following gene: 209551540

Centisome position: 90.98

GC content: 59.64

Gene sequence:

>996_bases
ATGAGTATCGCGACTGAGATTATCGGGGTGCCGGAAACGTTGGATCACTTCCAGTCGGACTCCTATTCGCCCTACCACTT
CTTCTCTTCCGAACAATGGGCGAAGTTCCGCGCCGACACGCCGCTGACGCTGACCAGCGACGAGGTCAAGCGGCTGCGTT
CGATGGGCGACCCGATCGATCTCGACGAGGTGAGGCGCATCTATCTGTCGCTGTCGCGGCTGCTGTCGGCGCATGTCGAA
TCCTCGCAGATGCTGTTCGAACAGCGAAACCGCTTCCTCAGCCTCTCCGATGTGACCAAGACGCCTTTCGTCATCGGCAT
CGCCGGCTCGGTCGCCGTCGGAAAATCGACCACGGCCCGCGTTCTCAAGGAACTACTGGGGCGCTGGCCTTCCAGCCCGA
AGGTCGATCTTGTCACCACCGACGGTTTCCTTCATCCGAATGCCGTGCTGCAGCGGGAAAAGCTGATGCAGCGCAAGGGT
TTTCCGGAGAGTTACGACACGGCTGCGATCCTGCGCTTTCTCTCGGCGATCAAGGCCGGGCAGCCGGATGTCAAGGCGCC
CAGCTATTCGCACCTCGTCTATGACGTGCTGCCCGACGAATACAAGATCGTCGACCGGCCGGACATCCTGATCTTCGAGG
GCATCAACGTGCTGCAATCGCGCGACCTGCCGGCCGGCGGCAAGATCGTGCCGATGGTCTCCGACTTCTTCGACTTCTCG
ATCTATATCGATGCCGCGGAAGATCTGATTCACAACTGGTACGTCGCACGTTTCATGCGGCTGCGCGAAACCGCCTTCCG
CGATCCGAATTCCTATTTCCATCGCTACGCTTCGATCAGCGACGCGGAAGCGCTCGAAATCGCCGGGGATCTCTGGGCGA
ACATCAACTTGAAAAACCTGCGGCAGAACATCCTGCCGACGCGCCCGCGTGCCGATCTCATCCTGAAAAAGGGCAAGGAC
CATCTGATCGAGCAGGTCGCGCTGCGGAAACTATAG

Upstream 100 bases:

>100_bases
TATTGAAGATTGCTGAAATACCGTTAGAGAATGTCATGGCCGAGCTCGAGCGCAGAACCGCGCAGTCCGGCCTCAAGGAA
AAGGCCGGCCGGCAGAGTTC

Downstream 100 bases:

>100_bases
CAGGCGATTCTTGCTGCCCATCAGCCTGGAGGATTGACGCGGCGCAGCGTCAGATTGATGCGGCCACCATTCTTCAAGAG
CGTCGACGTCGCCGGATGAA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSIATEIIGVPETLDHFQSDSYSPYHFFSSEQWAKFRADTPLTLTSDEVKRLRSMGDPIDLDEVRRIYLSLSRLLSAHVE
SSQMLFEQRNRFLSLSDVTKTPFVIGIAGSVAVGKSTTARVLKELLGRWPSSPKVDLVTTDGFLHPNAVLQREKLMQRKG
FPESYDTAAILRFLSAIKAGQPDVKAPSYSHLVYDVLPDEYKIVDRPDILIFEGINVLQSRDLPAGGKIVPMVSDFFDFS
IYIDAAEDLIHNWYVARFMRLRETAFRDPNSYFHRYASISDAEALEIAGDLWANINLKNLRQNILPTRPRADLILKKGKD
HLIEQVALRKL

Sequences:

>Translated_331_residues
MSIATEIIGVPETLDHFQSDSYSPYHFFSSEQWAKFRADTPLTLTSDEVKRLRSMGDPIDLDEVRRIYLSLSRLLSAHVE
SSQMLFEQRNRFLSLSDVTKTPFVIGIAGSVAVGKSTTARVLKELLGRWPSSPKVDLVTTDGFLHPNAVLQREKLMQRKG
FPESYDTAAILRFLSAIKAGQPDVKAPSYSHLVYDVLPDEYKIVDRPDILIFEGINVLQSRDLPAGGKIVPMVSDFFDFS
IYIDAAEDLIHNWYVARFMRLRETAFRDPNSYFHRYASISDAEALEIAGDLWANINLKNLRQNILPTRPRADLILKKGKD
HLIEQVALRKL
>Mature_330_residues
SIATEIIGVPETLDHFQSDSYSPYHFFSSEQWAKFRADTPLTLTSDEVKRLRSMGDPIDLDEVRRIYLSLSRLLSAHVES
SQMLFEQRNRFLSLSDVTKTPFVIGIAGSVAVGKSTTARVLKELLGRWPSSPKVDLVTTDGFLHPNAVLQREKLMQRKGF
PESYDTAAILRFLSAIKAGQPDVKAPSYSHLVYDVLPDEYKIVDRPDILIFEGINVLQSRDLPAGGKIVPMVSDFFDFSI
YIDAAEDLIHNWYVARFMRLRETAFRDPNSYFHRYASISDAEALEIAGDLWANINLKNLRQNILPTRPRADLILKKGKDH
LIEQVALRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Homo sapiens, GI13899253, Length=228, Percent_Identity=25.4385964912281, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790409, Length=312, Percent_Identity=54.1666666666667, Blast_Score=334, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 37617; Mature: 37485

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIATEIIGVPETLDHFQSDSYSPYHFFSSEQWAKFRADTPLTLTSDEVKRLRSMGDPID
CCCHHHHCCCCHHHHHHCCCCCCCEEECCCCHHHHHCCCCCCEECHHHHHHHHHCCCCCC
LDEVRRIYLSLSRLLSAHVESSQMLFEQRNRFLSLSDVTKTPFVIGIAGSVAVGKSTTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHCCCCCCEEEEECCCCCCCCCHHHH
VLKELLGRWPSSPKVDLVTTDGFLHPNAVLQREKLMQRKGFPESYDTAAILRFLSAIKAG
HHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
QPDVKAPSYSHLVYDVLPDEYKIVDRPDILIFEGINVLQSRDLPAGGKIVPMVSDFFDFS
CCCCCCCCHHHHHEECCCCCEEECCCCCEEEECCCHHHHCCCCCCCCEEHHHHHHHHCEE
IYIDAAEDLIHNWYVARFMRLRETAFRDPNSYFHRYASISDAEALEIAGDLWANINLKNL
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
RQNILPTRPRADLILKKGKDHLIEQVALRKL
HHHCCCCCCCHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SIATEIIGVPETLDHFQSDSYSPYHFFSSEQWAKFRADTPLTLTSDEVKRLRSMGDPID
CCHHHHCCCCHHHHHHCCCCCCCEEECCCCHHHHHCCCCCCEECHHHHHHHHHCCCCCC
LDEVRRIYLSLSRLLSAHVESSQMLFEQRNRFLSLSDVTKTPFVIGIAGSVAVGKSTTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEHHCCCCCCEEEEECCCCCCCCCHHHH
VLKELLGRWPSSPKVDLVTTDGFLHPNAVLQREKLMQRKGFPESYDTAAILRFLSAIKAG
HHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
QPDVKAPSYSHLVYDVLPDEYKIVDRPDILIFEGINVLQSRDLPAGGKIVPMVSDFFDFS
CCCCCCCCHHHHHEECCCCCEEECCCCCEEEECCCHHHHCCCCCCCCEEHHHHHHHHCEE
IYIDAAEDLIHNWYVARFMRLRETAFRDPNSYFHRYASISDAEALEIAGDLWANINLKNL
EEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHH
RQNILPTRPRADLILKKGKDHLIEQVALRKL
HHHCCCCCCCHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA