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The map label for this gene is dnaQ [H]

Identifier: 209551510

GI number: 209551510

Start: 4089194

End: 4089931

Strand: Direct

Name: dnaQ [H]

Synonym: Rleg2_3939

Alternate gene names: 209551510

Gene position: 4089194-4089931 (Clockwise)

Preceding gene: 209551509

Following gene: 209551513

Centisome position: 90.11

GC content: 60.98

Gene sequence:

>738_bases
ATGCGTGAGATCATCTTCGATACGGAAACCACCGGCCTCGACAACCGCGCCGACCGCATCATCGAAATCGGCGGCATCGA
GCTCTTCAATCATTTCCCGACCGGCAATGTGATCCATATCTACATCAATCCAGGCGATCAGAAGGTTCATCCGGATGCGC
TCGCCGTGCACGGCATCACCGACGAATTCCTGAAGGACAAGAAACCCTTCGCCGAGGTCGCCGAGGAAATCCTGACCTTC
TTCGGCGACGCCAAGTGGATTGCCCACAACGCCACCTTCGATATGGGCTTCATCAACGCCGAATTGGCGCGGATCGGTTT
GCCGCCGATCCTGCCGGAGCGGGTGCTTGACACCCTGTCGATGGCGCGGCGCAAACATCCGATGGGGCCGAATTCGCTCG
ACGCGCTCTGCCGACGTTACGGCATCGACAATTCGCACCGCACCAAACACGGCGCGCTGCTCGACTCCGAACTGCTCGCC
GAAGTCTATATCGAGATGATCGGCGGCAGGCAGGCAGCTTTCGGCCTGAGCATGACCGCTACATCAGGGCAGAACGGTCG
CGGCGATGCGACTGAGGAAGACGATGTGGTGATTGCATCCGTGCTCGAGCGGCCCCGCCCGCTTGCCCCCCGCCTCAGCC
AGTCCGAGGCGCAGGCGCATGAGGCGCTCGTCGCCAAGCTCGGCGAAAAAGGCATCTGGGCGAAATATGCCAGCCTGGAC
CAAACCGGCCACAATTGA

Upstream 100 bases:

>100_bases
TATCTGATCGACAGCAGCCGCAGTATCGCGGAGACGAAGGAACGGGTGCTGGAGATTATCGCCGACCTGAAAACGCGGAT
TGACAAGGGAGATTTCCGGA

Downstream 100 bases:

>100_bases
AAATGCCCGGGACTTGCCCGGGCATCCGCATCTCAAAACCGAAAAATCCGATCAGTTCGGAACGGCTTCAACCTTGGCGC
GGGCCTGTTCTTCGGCAACG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MREIIFDTETTGLDNRADRIIEIGGIELFNHFPTGNVIHIYINPGDQKVHPDALAVHGITDEFLKDKKPFAEVAEEILTF
FGDAKWIAHNATFDMGFINAELARIGLPPILPERVLDTLSMARRKHPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLA
EVYIEMIGGRQAAFGLSMTATSGQNGRGDATEEDDVVIASVLERPRPLAPRLSQSEAQAHEALVAKLGEKGIWAKYASLD
QTGHN

Sequences:

>Translated_245_residues
MREIIFDTETTGLDNRADRIIEIGGIELFNHFPTGNVIHIYINPGDQKVHPDALAVHGITDEFLKDKKPFAEVAEEILTF
FGDAKWIAHNATFDMGFINAELARIGLPPILPERVLDTLSMARRKHPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLA
EVYIEMIGGRQAAFGLSMTATSGQNGRGDATEEDDVVIASVLERPRPLAPRLSQSEAQAHEALVAKLGEKGIWAKYASLD
QTGHN
>Mature_245_residues
MREIIFDTETTGLDNRADRIIEIGGIELFNHFPTGNVIHIYINPGDQKVHPDALAVHGITDEFLKDKKPFAEVAEEILTF
FGDAKWIAHNATFDMGFINAELARIGLPPILPERVLDTLSMARRKHPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLA
EVYIEMIGGRQAAFGLSMTATSGQNGRGDATEEDDVVIASVLERPRPLAPRLSQSEAQAHEALVAKLGEKGIWAKYASLD
QTGHN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=245, Percent_Identity=43.6734693877551, Blast_Score=175, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26975; Mature: 26975

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIIFDTETTGLDNRADRIIEIGGIELFNHFPTGNVIHIYINPGDQKVHPDALAVHGIT
CCCEEECCCCCCCCCHHHHEEEECCEEEECCCCCCCEEEEEECCCCCCCCCCCEEECCCC
DEFLKDKKPFAEVAEEILTFFGDAKWIAHNATFDMGFINAELARIGLPPILPERVLDTLS
HHHHHCCCCHHHHHHHHHHHHCCCCEEEECCEECCHHHHHHHHHHCCCCCCHHHHHHHHH
MARRKHPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLAEVYIEMIGGRQAAFGLSMTA
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEE
TSGQNGRGDATEEDDVVIASVLERPRPLAPRLSQSEAQAHEALVAKLGEKGIWAKYASLD
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCC
QTGHN
CCCCC
>Mature Secondary Structure
MREIIFDTETTGLDNRADRIIEIGGIELFNHFPTGNVIHIYINPGDQKVHPDALAVHGIT
CCCEEECCCCCCCCCHHHHEEEECCEEEECCCCCCCEEEEEECCCCCCCCCCCEEECCCC
DEFLKDKKPFAEVAEEILTFFGDAKWIAHNATFDMGFINAELARIGLPPILPERVLDTLS
HHHHHCCCCHHHHHHHHHHHHCCCCEEEECCEECCHHHHHHHHHHCCCCCCHHHHHHHHH
MARRKHPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLAEVYIEMIGGRQAAFGLSMTA
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEE
TSGQNGRGDATEEDDVVIASVLERPRPLAPRLSQSEAQAHEALVAKLGEKGIWAKYASLD
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHCC
QTGHN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]