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The map label for this gene is obgE [H]

Identifier: 209551445

GI number: 209551445

Start: 4015136

End: 4016230

Strand: Direct

Name: obgE [H]

Synonym: Rleg2_3874

Alternate gene names: 209551445

Gene position: 4015136-4016230 (Clockwise)

Preceding gene: 209551443

Following gene: 209551446

Centisome position: 88.48

GC content: 62.01

Gene sequence:

>1095_bases
ATGAAATTTCTCGACGAAGCAAAGGTCTATATCCGATCCGGAGACGGCGGCGGGGGCAGCGTTTCCTTCCGGCGCGAGAA
ATTCATCGAGTTCGGCGGCCCCGATGGCGGTGATGGCGGACGCGGCGGCGATGTCTGGGTCGAGACCGTCAACGGCCTCA
ATACGCTGATCGATTTCCGTTTTCAGCAGCATTTCAAGGCGACGATCGGCACCCATGGCATGGGCAGGAACCGCACGGGC
GCCAATGGCAGCGACGTGACGCTGAAGGTTCCCGTGGGAACCCAGATCTTCGAGGAAGATCGGGAAACGCTGATCTGCGA
TCTCACCGTCGAAGGCCAGCGTTATTGCCTGGCCCATGGCGGCAATGGCGGCTTCGGCAACGCTCATTTCAAGACCTCGA
CCAACCAAGCGCCGGATTGGGCCAATCCGGGCCTGCCCGGCGAGGAAAAGACCCTCTGGCTGCGGCTCAAGCTGATTGCC
GATGCCGGCCTCGTCGGCATGCCCAATGCCGGCAAGTCGACCTTCCTGGCATCGGTCACCCGCGCCCGGCCGAAGATCGC
CAACTATCCCTTCACCACGCTGCATCCCAATCTCGGCGTCGCCACCATCGACGAACGGGAATTCATCCTGGCCGACATTC
CGGGCCTGATCGAAGGCGCCCATGAGGGCGTCGGCATCGGCGACCGTTTCCTCGGCCATGTCGAGCGCACCCGCGTGCTG
CTGCACCTCGTCTCCGCCCAGGAGGAAAAGGTCGGCAAAGCCTATAAGACGGTCAAACACGAGCTCGAAGCCTATGGCAA
CGAGCTGACTGATAAGCCGGAGATCGTGGCGCTGTCGCAGATCGACGTGCTCGACGAGGCCGAACTGAAGAAGAAGACCA
AGGAATTGGCCAAGGCCTGCGGCAAGACACCGTTCCAGATTTCTGCCGTCACCGGCAAGGGCATGACCGAGGTGCTGCGT
GCGCTGCGCGACATCATCGTCGAGGAAAATGCCGAGGAAAAGCCGGCTAAGGTGCCGAAGCAGCGCCACCGCGACATTGT
TGTCGCCGATGAGGGCGAGGACGTTGGCGAGGATGGGGCCGATGACCAGCCGTAA

Upstream 100 bases:

>100_bases
AGCTCGCAAAATTCACGATAATCTTTGACCTCCGTCGGAACCGCCTATATCGAATGGGCCAAGACGGGCCGTCCAACTGC
CACCGGATACTGGAAGTAAA

Downstream 100 bases:

>100_bases
GCCGCTTGGACGCTACCGCCGCATCGTCATCAAGATCGGCTCGGCGCTGCTGGTCGACCGCAAGGCCGGCCTGAAGAAGG
CCTGGCTCGACGCCATGTGC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKFLDEAKVYIRSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVETVNGLNTLIDFRFQQHFKATIGTHGMGRNRTG
ANGSDVTLKVPVGTQIFEEDRETLICDLTVEGQRYCLAHGGNGGFGNAHFKTSTNQAPDWANPGLPGEEKTLWLRLKLIA
DAGLVGMPNAGKSTFLASVTRARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKACGKTPFQISAVTGKGMTEVLR
ALRDIIVEENAEEKPAKVPKQRHRDIVVADEGEDVGEDGADDQP

Sequences:

>Translated_364_residues
MKFLDEAKVYIRSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVETVNGLNTLIDFRFQQHFKATIGTHGMGRNRTG
ANGSDVTLKVPVGTQIFEEDRETLICDLTVEGQRYCLAHGGNGGFGNAHFKTSTNQAPDWANPGLPGEEKTLWLRLKLIA
DAGLVGMPNAGKSTFLASVTRARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKACGKTPFQISAVTGKGMTEVLR
ALRDIIVEENAEEKPAKVPKQRHRDIVVADEGEDVGEDGADDQP
>Mature_364_residues
MKFLDEAKVYIRSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVETVNGLNTLIDFRFQQHFKATIGTHGMGRNRTG
ANGSDVTLKVPVGTQIFEEDRETLICDLTVEGQRYCLAHGGNGGFGNAHFKTSTNQAPDWANPGLPGEEKTLWLRLKLIA
DAGLVGMPNAGKSTFLASVTRARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVL
LHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKACGKTPFQISAVTGKGMTEVLR
ALRDIIVEENAEEKPAKVPKQRHRDIVVADEGEDVGEDGADDQP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=334, Percent_Identity=37.125748502994, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI111955139, Length=372, Percent_Identity=35.2150537634409, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI111955063, Length=258, Percent_Identity=33.7209302325581, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI58761500, Length=104, Percent_Identity=37.5, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1789574, Length=350, Percent_Identity=48.8571428571429, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI1787454, Length=106, Percent_Identity=36.7924528301887, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=36.4197530864198, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17552324, Length=365, Percent_Identity=29.3150684931507, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17509631, Length=102, Percent_Identity=38.2352941176471, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=121, Percent_Identity=34.7107438016529, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=113, Percent_Identity=45.1327433628319, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI20129375, Length=326, Percent_Identity=35.8895705521472, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24585318, Length=277, Percent_Identity=36.101083032491, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24640873, Length=119, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640877, Length=119, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640875, Length=119, Percent_Identity=35.2941176470588, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17981711, Length=114, Percent_Identity=37.719298245614, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=35.042735042735, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39454; Mature: 39454

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDEAKVYIRSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVETVNGLNTLIDFR
CCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
FQQHFKATIGTHGMGRNRTGANGSDVTLKVPVGTQIFEEDRETLICDLTVEGQRYCLAHG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCEEEEEEEECCCEEEEEEC
GNGGFGNAHFKTSTNQAPDWANPGLPGEEKTLWLRLKLIADAGLVGMPNAGKSTFLASVT
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEECCCCCCCHHHHHHHH
RARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVL
HCCCCCCCCCCEEECCCCCEEEECCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHH
LHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKAC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
GKTPFQISAVTGKGMTEVLRALRDIIVEENAEEKPAKVPKQRHRDIVVADEGEDVGEDGA
CCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCCC
DDQP
CCCC
>Mature Secondary Structure
MKFLDEAKVYIRSGDGGGGSVSFRREKFIEFGGPDGGDGGRGGDVWVETVNGLNTLIDFR
CCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
FQQHFKATIGTHGMGRNRTGANGSDVTLKVPVGTQIFEEDRETLICDLTVEGQRYCLAHG
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHCCCCEEEEEEEECCCEEEEEEC
GNGGFGNAHFKTSTNQAPDWANPGLPGEEKTLWLRLKLIADAGLVGMPNAGKSTFLASVT
CCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCEECCCCCCCHHHHHHHH
RARPKIANYPFTTLHPNLGVATIDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVL
HCCCCCCCCCCEEECCCCCEEEECCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHHHH
LHLVSAQEEKVGKAYKTVKHELEAYGNELTDKPEIVALSQIDVLDEAELKKKTKELAKAC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
GKTPFQISAVTGKGMTEVLRALRDIIVEENAEEKPAKVPKQRHRDIVVADEGEDVGEDGA
CCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCEEEEECCCCCCCCCCC
DDQP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA