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The map label for this gene is yvrH [H]

Identifier: 209551334

GI number: 209551334

Start: 3886407

End: 3887090

Strand: Direct

Name: yvrH [H]

Synonym: Rleg2_3763

Alternate gene names: 209551334

Gene position: 3886407-3887090 (Clockwise)

Preceding gene: 209551331

Following gene: 209551335

Centisome position: 85.64

GC content: 60.38

Gene sequence:

>684_bases
ATGACCGCACGCACCATTCTTCTGGTGGATGACGACGATGACCTTCGTCAGACGCTGACGGAGCAATTGTCGCTGTATGA
GGAATTTTCGGTTCTGCAGGAAGCCAACGCCGGCAAGGGTGTTGCAACCGCCCGCTCGACACCGGTCGATCTGTTGATCA
TGGATGTCGGCCTGCCCGATATGGACGGCCGCGAGGCGGTCAAGCTGCTGCGCAAAGGCGGCTTCAAGGCGCCGATCATC
ATGCTGACCGGCCACGATACCGATTCGGACACGATCCTCGGCCTCGAAGCCGGCGCCAACGACTATGTTACCAAGCCTTT
CCGCTTCGCCGTGCTGCTCGCGCGCATCCGCGTGCAGCTGCGCCAGCACGAGCAGAGCGAGGACGCCACCTTCACCGTCG
GCCCCTACCTCTTCAAGCCGAGCCAGAAGCTGCTGACCACCGAGAATGGTCAGAAGATCCGCCTGACGGAAAAGGAAGCG
GCGATCATCCGCTACCTCTACCGCGCCGAACAGAAGGTCGTGACCCGCGACGTGCTTCTCGAAGAGGTTTGGGGCTATAA
CTCCGGCGTGACGACGCATACGCTGGAAACCCATGTCTACCGCCTGCGCCAGAAGATCGAACGCGATCCCTCTAATGCCG
AAATCCTGGTGACGGAAAACGGCGGCTACAAGATCATACCCTAG

Upstream 100 bases:

>100_bases
ATCATATCAAAACCTGCGCGGCAACAGCCCGCCGCCCCATCCTTGCCAAACCAGGAATTTGGCGTAGGACTAGGGGACTT
AACATGAGGAAAGCAAGGGC

Downstream 100 bases:

>100_bases
GGCATTTCCGTTTTCTCAGAATACGAAAATGCTCTATCTCTTTGTTTTCACGCAATTCCGGAATGCAAGACCGCGACGCA
GTTTTGCTGGGATTGCTCTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTARTILLVDDDDDLRQTLTEQLSLYEEFSVLQEANAGKGVATARSTPVDLLIMDVGLPDMDGREAVKLLRKGGFKAPII
MLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRVQLRQHEQSEDATFTVGPYLFKPSQKLLTTENGQKIRLTEKEA
AIIRYLYRAEQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIIP

Sequences:

>Translated_227_residues
MTARTILLVDDDDDLRQTLTEQLSLYEEFSVLQEANAGKGVATARSTPVDLLIMDVGLPDMDGREAVKLLRKGGFKAPII
MLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRVQLRQHEQSEDATFTVGPYLFKPSQKLLTTENGQKIRLTEKEA
AIIRYLYRAEQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIIP
>Mature_226_residues
TARTILLVDDDDDLRQTLTEQLSLYEEFSVLQEANAGKGVATARSTPVDLLIMDVGLPDMDGREAVKLLRKGGFKAPIIM
LTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRVQLRQHEQSEDATFTVGPYLFKPSQKLLTTENGQKIRLTEKEAA
IIRYLYRAEQKVVTRDVLLEEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIIP

Specific function: Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA- yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX- rsiX), and negatively regulates the lytABC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=33.6322869955157, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=32.4444444444444, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=31.140350877193, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789402, Length=208, Percent_Identity=29.8076923076923, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.304347826087, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787375, Length=174, Percent_Identity=31.6091954022989, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=27.3127753303965, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=29.2576419213974, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=34.4497607655502, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=28.1938325991189, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=27.0042194092827, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=26.9911504424779, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=29.7071129707113, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788550, Length=172, Percent_Identity=26.7441860465116, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25550; Mature: 25418

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTILLVDDDDDLRQTLTEQLSLYEEFSVLQEANAGKGVATARSTPVDLLIMDVGLPD
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCC
MDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRVQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RQHEQSEDATFTVGPYLFKPSQKLLTTENGQKIRLTEKEAAIIRYLYRAEQKVVTRDVLL
HHCCCCCCCEEEECCEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIIP
HHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure 
TARTILLVDDDDDLRQTLTEQLSLYEEFSVLQEANAGKGVATARSTPVDLLIMDVGLPD
CCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCC
MDGREAVKLLRKGGFKAPIIMLTGHDTDSDTILGLEAGANDYVTKPFRFAVLLARIRVQL
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
RQHEQSEDATFTVGPYLFKPSQKLLTTENGQKIRLTEKEAAIIRYLYRAEQKVVTRDVLL
HHCCCCCCCEEEECCEEECCCCCEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
EEVWGYNSGVTTHTLETHVYRLRQKIERDPSNAEILVTENGGYKIIP
HHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]