Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 209551256

GI number: 209551256

Start: 3814349

End: 3815542

Strand: Reverse

Name: sucC [H]

Synonym: Rleg2_3684

Alternate gene names: 209551256

Gene position: 3815542-3814349 (Counterclockwise)

Preceding gene: 209551257

Following gene: 209551255

Centisome position: 84.08

GC content: 61.14

Gene sequence:

>1194_bases
ATGAACATTCATGAATATCAAGCCAAGGCTCTGCTGAAGGGCTATGGCGCGCCGGTTGCCGAGGGTGTGGCTATTCTCAA
GGTCGAAGAGGCCGCGGCTGCCGCCAAATCGCTTCCCGGTCCGCTTTACGTGGTCAAGAGCCAGATCCATGCCGGCGGCC
GCGGCAAGGGCAAGTTCAAGGAACTGTCGCCGGAGGCCAAGGGCGGCGTGCGTCTCGCCAAGTCGATCGAGGAAGTGGTT
GCCCACGCCAAGGAAATGCTTGGGAATACGCTGGTGACGGCACAGACCGGCGACGCCGGCAAGCAGGTCAACCGCCTCTA
CATCGAAGACGGCGCCGACATCGCTCGCGAGCTCTATTGCTCGATCCTTGTCGACCGTTCGGTCGGCCGCGTGGCTTTCG
TGGTTTCCACAGAAGGCGGCATGGACATCGAGGCTGTCGCCCATGACACGCCGGAGAAGATCCAGACGATCGCCATCGAT
CCGGAAGCCGGCGTGACGGCTGCTGACGTTGCTGCGATCTCCAAGGCTCTGCAACTCGACGGTGCGGCCGCCGAAGATGC
CAAGTCGCTCTTCCCGGCGCTCTACAAGGCCTTCAACGAAAAGGACATGGCGCTGCTCGAGGTCAATCCGCTGATCGTCA
TGAAGGACGGTCACCTGCGGGTTCTCGACGCCAAGATGTCCTTCGACGGCAATGCGCTCTTCCGTCACGACGACGTCAAG
ACGCTGCGCGACGAAACCGAAGAAGACGCCAAGGAAATCGAGGCCTCGAAGTGGGACCTCGCCTATGTCGCGCTCGACGG
CAATATCGGCTGCATGGTCAACGGCGCCGGCCTTGCCATGGCGACGATGGATATTATCAAGCTCTACGGCAAGGAGCCGG
CTAACTTCTGCGACGTCGGCGGCGGCGCCGGCAAGGAGAAGGTTGCTGCGGCTTTCAAGATCATCACCGCGGACCCCAAG
GTCGAAGGCATTCTCGTCAACATCTTCGGCGGCATCATGAAGTGCGATGTCATCGCCGAGGGCGTCATTGCCGCGGTCAA
GGAAGTCGGTCTCAAGGTTCCGCTCGTCGTGCGCCTTGAAGGCACCAATGTCGAACTCGGCAAGAAGATCCTGAACGAGT
CGGGTCTGGCGATCACGGCGGCTGACGACTTGGACGATGCGGCCAAGAAGATCGTCGCGGCGATTAACGGCTGA

Upstream 100 bases:

>100_bases
AAGTCCGTCGGCGCCGTCGCCGGTCTCTGCGAAGCCTGCATCAATATCGCGCCTGCCCTCAAGTAATTGGCGCTGAACTA
ATCCAAACAGGGATAGACCC

Downstream 100 bases:

>100_bases
GAGCGATCATGGCCTTCCAGTCCACGCCATCTGCTGCTCATATCCGCCTCAACGCCTTTTCCGGCGTATGGGAAGGGGAG
GAGCGTGTCGCAGGGTCGGC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAAAAAKSLPGPLYVVKSQIHAGGRGKGKFKELSPEAKGGVRLAKSIEEVV
AHAKEMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYCSILVDRSVGRVAFVVSTEGGMDIEAVAHDTPEKIQTIAID
PEAGVTAADVAAISKALQLDGAAAEDAKSLFPALYKAFNEKDMALLEVNPLIVMKDGHLRVLDAKMSFDGNALFRHDDVK
TLRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVGGGAGKEKVAAAFKIITADPK
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKILNESGLAITAADDLDDAAKKIVAAING

Sequences:

>Translated_397_residues
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAAAAAKSLPGPLYVVKSQIHAGGRGKGKFKELSPEAKGGVRLAKSIEEVV
AHAKEMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYCSILVDRSVGRVAFVVSTEGGMDIEAVAHDTPEKIQTIAID
PEAGVTAADVAAISKALQLDGAAAEDAKSLFPALYKAFNEKDMALLEVNPLIVMKDGHLRVLDAKMSFDGNALFRHDDVK
TLRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVGGGAGKEKVAAAFKIITADPK
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKILNESGLAITAADDLDDAAKKIVAAING
>Mature_397_residues
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAAAAAKSLPGPLYVVKSQIHAGGRGKGKFKELSPEAKGGVRLAKSIEEVV
AHAKEMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYCSILVDRSVGRVAFVVSTEGGMDIEAVAHDTPEKIQTIAID
PEAGVTAADVAAISKALQLDGAAAEDAKSLFPALYKAFNEKDMALLEVNPLIVMKDGHLRVLDAKMSFDGNALFRHDDVK
TLRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVGGGAGKEKVAAAFKIITADPK
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKILNESGLAITAADDLDDAAKKIVAAING

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=44.1326530612245, Blast_Score=322, Evalue=5e-88,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=47.1502590673575, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=46.027397260274, Blast_Score=294, Evalue=1e-79,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=52.1410579345088, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=44.8101265822785, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=44.0506329113924, Blast_Score=307, Evalue=7e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=44.0506329113924, Blast_Score=327, Evalue=2e-90,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=47.8589420654912, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=46.3917525773196, Blast_Score=320, Evalue=9e-88,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=46.3917525773196, Blast_Score=320, Evalue=9e-88,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=46.5295629820051, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=46.5295629820051, Blast_Score=320, Evalue=1e-87,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41692; Mature: 41692

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAAAAAKSLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHCCCCHHCCEEEEEEHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCC
ELSPEAKGGVRLAKSIEEVVAHAKEMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYC
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEECCHHHHHHHHH
SILVDRSVGRVAFVVSTEGGMDIEAVAHDTPEKIQTIAIDPEAGVTAADVAAISKALQLD
HHHEECCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
GAAAEDAKSLFPALYKAFNEKDMALLEVNPLIVMKDGHLRVLDAKMSFDGNALFRHDDVK
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCEEEEEEEECCCCCEEEECCCHH
TLRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVG
HHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEECCC
GGAGKEKVAAAFKIITADPKVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLE
CCCCHHHHHEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKILNESGLAITAADDLDDAAKKIVAAING
CCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKALLKGYGAPVAEGVAILKVEEAAAAAKSLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHCCCCHHCCEEEEEEHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCC
ELSPEAKGGVRLAKSIEEVVAHAKEMLGNTLVTAQTGDAGKQVNRLYIEDGADIARELYC
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEECCHHHHHHHHH
SILVDRSVGRVAFVVSTEGGMDIEAVAHDTPEKIQTIAIDPEAGVTAADVAAISKALQLD
HHHEECCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
GAAAEDAKSLFPALYKAFNEKDMALLEVNPLIVMKDGHLRVLDAKMSFDGNALFRHDDVK
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCEEEEEEEECCCCCEEEECCCHH
TLRDETEEDAKEIEASKWDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGKEPANFCDVG
HHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEECCC
GGAGKEKVAAAFKIITADPKVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLE
CCCCHHHHHEEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKILNESGLAITAADDLDDAAKKIVAAING
CCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]