Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 209551174

GI number: 209551174

Start: 3722826

End: 3723779

Strand: Direct

Name: xerD [H]

Synonym: Rleg2_3598

Alternate gene names: 209551174

Gene position: 3722826-3723779 (Clockwise)

Preceding gene: 209551173

Following gene: 209551175

Centisome position: 82.04

GC content: 64.78

Gene sequence:

>954_bases
ATGGTGGATCTGAGCCGCGTCCATGTGGAATCCTTCCTGGAGATGATGAGCGCCGAGCGCGGCGCCGCCGTCAACACGCT
GCAATCCTATGAGCGCGACCTCGACGATGTCCACGCCTTCCTGACCGGGCGCAGCGTGCGGCTGACCGAAGCCGCCTCCG
CCGATCTGGCCGCCTATCTCGCCTCGCTCGCCCGAAAGGGCTTCAAAGCCTCGTCACAGGCGCGCCGGCTTGCCGCCATG
CGGCAGTTCTACAAGTTCCTCTACGCCGAGGGGCTGAGGACCGACGATCCCACCGGCATTCTCGACGCGCCGAAGAAAGG
CCGTCCGCTGCCGAAGACGATGGGCGTCGAGGAGGTCGGCAAGCTGCTTTCCCAGGCTGAGGCCGAGGCAGGCGATGCAG
CGCCCGGCCAGCTGCAGCGCCTGCGCATGCTGGCGCTGCTGGAGCTGCTCTATGCCACCGGCATGCGTGTCAGCGAACTG
GTTTCGCTTCCCGCCCGCGTGCTCGATCAGGAAGGGCGTTTCCTGATGATCCGCGGCAAAGGCAACAAGGAGCGGCTGGT
GCCCCTGTCGCAATCGGCGATATCGGCGTTGAAATCCTACGGGCGCCTGCTGGCGGCGGAAAATGCCGCGGCCAAGAATC
CGCAGGAAAGTCCCTGGCTGTTTCCCGCCGCCTCGAAGGAGGGCTATCTGCCGCGCCAGGTTTTTGCCCGCGACCTCAAG
AACCTGGCGATCCGCGCCGGCCTGACGCCGTCGATGATCTCGCCGCATGTGATGCGCCACGCCTTTGCCAGCCACCTGCT
TGCCAATGGCGCCGACCTGCGCGTCGTGCAGGAACTCCTCGGCCATTCGGACATTTCGACCACACAGATTTACACGCATG
TCCTCGAAGAGAGGCTCCAGCAGCTCGTCCAGACGCATCACCCCCTTGCCAAACAGGCGAAAAAGCACGAATAG

Upstream 100 bases:

>100_bases
TTCGTCGAGCCCGAGCCGCGCGACGTGACCATCCGTATTCCGTCCGAGCGGGTCAATCCGCCGGCGACGGGCACGATCAA
CACGACCAGGAAGTGACCGC

Downstream 100 bases:

>100_bases
GACCGGCGACAAGGGGCGGAGCCAGGAAAACGCCCCGGGCACAAGGAACGGAAACGCACCTCATGCACAATTATCTCGAC
TTCGAAAAGCCGATCTCCGA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MVDLSRVHVESFLEMMSAERGAAVNTLQSYERDLDDVHAFLTGRSVRLTEAASADLAAYLASLARKGFKASSQARRLAAM
RQFYKFLYAEGLRTDDPTGILDAPKKGRPLPKTMGVEEVGKLLSQAEAEAGDAAPGQLQRLRMLALLELLYATGMRVSEL
VSLPARVLDQEGRFLMIRGKGNKERLVPLSQSAISALKSYGRLLAAENAAAKNPQESPWLFPAASKEGYLPRQVFARDLK
NLAIRAGLTPSMISPHVMRHAFASHLLANGADLRVVQELLGHSDISTTQIYTHVLEERLQQLVQTHHPLAKQAKKHE

Sequences:

>Translated_317_residues
MVDLSRVHVESFLEMMSAERGAAVNTLQSYERDLDDVHAFLTGRSVRLTEAASADLAAYLASLARKGFKASSQARRLAAM
RQFYKFLYAEGLRTDDPTGILDAPKKGRPLPKTMGVEEVGKLLSQAEAEAGDAAPGQLQRLRMLALLELLYATGMRVSEL
VSLPARVLDQEGRFLMIRGKGNKERLVPLSQSAISALKSYGRLLAAENAAAKNPQESPWLFPAASKEGYLPRQVFARDLK
NLAIRAGLTPSMISPHVMRHAFASHLLANGADLRVVQELLGHSDISTTQIYTHVLEERLQQLVQTHHPLAKQAKKHE
>Mature_317_residues
MVDLSRVHVESFLEMMSAERGAAVNTLQSYERDLDDVHAFLTGRSVRLTEAASADLAAYLASLARKGFKASSQARRLAAM
RQFYKFLYAEGLRTDDPTGILDAPKKGRPLPKTMGVEEVGKLLSQAEAEAGDAAPGQLQRLRMLALLELLYATGMRVSEL
VSLPARVLDQEGRFLMIRGKGNKERLVPLSQSAISALKSYGRLLAAENAAAKNPQESPWLFPAASKEGYLPRQVFARDLK
NLAIRAGLTPSMISPHVMRHAFASHLLANGADLRVVQELLGHSDISTTQIYTHVLEERLQQLVQTHHPLAKQAKKHE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=321, Percent_Identity=44.5482866043614, Blast_Score=231, Evalue=6e-62,
Organism=Escherichia coli, GI1790244, Length=322, Percent_Identity=32.9192546583851, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790768, Length=178, Percent_Identity=32.0224719101124, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34914; Mature: 34914

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLSRVHVESFLEMMSAERGAAVNTLQSYERDLDDVHAFLTGRSVRLTEAASADLAAYL
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
ASLARKGFKASSQARRLAAMRQFYKFLYAEGLRTDDPTGILDAPKKGRPLPKTMGVEEVG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHH
KLLSQAEAEAGDAAPGQLQRLRMLALLELLYATGMRVSELVSLPARVLDQEGRFLMIRGK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECC
GNKERLVPLSQSAISALKSYGRLLAAENAAAKNPQESPWLFPAASKEGYLPRQVFARDLK
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
NLAIRAGLTPSMISPHVMRHAFASHLLANGADLRVVQELLGHSDISTTQIYTHVLEERLQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QLVQTHHPLAKQAKKHE
HHHHHHCHHHHHHHCCC
>Mature Secondary Structure
MVDLSRVHVESFLEMMSAERGAAVNTLQSYERDLDDVHAFLTGRSVRLTEAASADLAAYL
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHH
ASLARKGFKASSQARRLAAMRQFYKFLYAEGLRTDDPTGILDAPKKGRPLPKTMGVEEVG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHH
KLLSQAEAEAGDAAPGQLQRLRMLALLELLYATGMRVSELVSLPARVLDQEGRFLMIRGK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECC
GNKERLVPLSQSAISALKSYGRLLAAENAAAKNPQESPWLFPAASKEGYLPRQVFARDLK
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
NLAIRAGLTPSMISPHVMRHAFASHLLANGADLRVVQELLGHSDISTTQIYTHVLEERLQ
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QLVQTHHPLAKQAKKHE
HHHHHHCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]