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The map label for this gene is cobS [H]

Identifier: 209551167

GI number: 209551167

Start: 3717123

End: 3718115

Strand: Reverse

Name: cobS [H]

Synonym: Rleg2_3591

Alternate gene names: 209551167

Gene position: 3718115-3717123 (Counterclockwise)

Preceding gene: 209551168

Following gene: 209551166

Centisome position: 81.93

GC content: 61.23

Gene sequence:

>993_bases
ATGAGCAAGATCGACCTCGATATTTCTGAACTGCCCGATACCACCGTTTCGGTCCGCGAGGCCTTCGGCATCGATTCCGA
CATCCGCGTTCCCGCCTACAGCAAGGGCGACGCCTATGTGCCGGACCTCGACACCGACTACCTCTTCGACCGCGACACGA
CGCTCGCCATTCTTGCAGGCTTCGCCCATAACCGTCGCGTGATGATCTCCGGCTATCACGGCACCGGCAAGTCCTCGCAT
ATCGAGCAGGTCGCGGCGCGCCTCAACTGGCCCTGCGTGCGCATCAACCTCGACAGCCATGTCAGCCGTATCGATCTCGT
CGGCAAGGATGCGATCGTCGTCAAGGACGGGCTGCAGGTCACCGAGTTCAAGGACGGCATCCTGCCCTGGGCCTATCAGC
ACAATGTCGCGCTGGTCTTCGACGAATATGATGCCGGCCGCCCCGATGTGATGTTCGTCATCCAGCGCGTGCTGGAATCC
TCCGGCCGCCTGACATTGCTCGACCAGAGCCGCGTCATCCGGCCGCACCCGGCCTTCCGCCTGTTTGCGACCGCTAATAC
GATCGGTCTCGGCGACACTACCGGCCTCTATCACGGCACGCAGCAGATCAATCAGGCGCAGATGGACCGCTGGTCGATCG
TGACGACGCTGAACTACCTGCCGCATGATCACGAAGTGAATATCGTCGCCGCCAAGGTAAAGAGCTTCGGCAAGGACAGG
GAAGGCCGCGACACCGTTTCGAAGATGGTTCGTGTCGCCGATCTGACGCGCGCCGCCTTCATGAATGGTGATCTCTCCAC
CGTCATGAGCCCGCGTACCGTCATCACCTGGGCCGAGAATGCCGAGATCTTCGGCGATCTGGCCTTCGCCTTCCGCGTCA
CCTTCCTCAACAAGTGCGACGAATTGGAGCGTCCTCTGGTCGCCGAGCACTATCAGCGGGCCTTCGGCGTCGAGCTGAAG
GAAAGTGCCGCCAATATCGTTCTCGGAGCCTGA

Upstream 100 bases:

>100_bases
CGTTCCGACCTGGACGGGCGCGGAATAAAATCGCGGCGTCACGGTTGCGACATGGCCTGAGACAGTATGGCCGGGTGGCA
TCACCCGCCTTGGAGACATG

Downstream 100 bases:

>100_bases
GACCGACCGATCATGGCAGCTCGCGGTGACAATTCGAAAGCAAAGCCCGGCGCGCCCGTCGACGTCGAGCCATTGCGCCG
GGCGATATCCGGCTGCGTGC

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSKIDLDISELPDTTVSVREAFGIDSDIRVPAYSKGDAYVPDLDTDYLFDRDTTLAILAGFAHNRRVMISGYHGTGKSSH
IEQVAARLNWPCVRINLDSHVSRIDLVGKDAIVVKDGLQVTEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLES
SGRLTLLDQSRVIRPHPAFRLFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDHEVNIVAAKVKSFGKDR
EGRDTVSKMVRVADLTRAAFMNGDLSTVMSPRTVITWAENAEIFGDLAFAFRVTFLNKCDELERPLVAEHYQRAFGVELK
ESAANIVLGA

Sequences:

>Translated_330_residues
MSKIDLDISELPDTTVSVREAFGIDSDIRVPAYSKGDAYVPDLDTDYLFDRDTTLAILAGFAHNRRVMISGYHGTGKSSH
IEQVAARLNWPCVRINLDSHVSRIDLVGKDAIVVKDGLQVTEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLES
SGRLTLLDQSRVIRPHPAFRLFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDHEVNIVAAKVKSFGKDR
EGRDTVSKMVRVADLTRAAFMNGDLSTVMSPRTVITWAENAEIFGDLAFAFRVTFLNKCDELERPLVAEHYQRAFGVELK
ESAANIVLGA
>Mature_329_residues
SKIDLDISELPDTTVSVREAFGIDSDIRVPAYSKGDAYVPDLDTDYLFDRDTTLAILAGFAHNRRVMISGYHGTGKSSHI
EQVAARLNWPCVRINLDSHVSRIDLVGKDAIVVKDGLQVTEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLESS
GRLTLLDQSRVIRPHPAFRLFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDHEVNIVAAKVKSFGKDRE
GRDTVSKMVRVADLTRAAFMNGDLSTVMSPRTVITWAENAEIFGDLAFAFRVTFLNKCDELERPLVAEHYQRAFGVELKE
SAANIVLGA

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=178, Percent_Identity=28.6516853932584, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323135, Length=145, Percent_Identity=30.3448275862069, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076560, Length=145, Percent_Identity=28.9655172413793, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076562, Length=145, Percent_Identity=28.9655172413793, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36785; Mature: 36654

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIDLDISELPDTTVSVREAFGIDSDIRVPAYSKGDAYVPDLDTDYLFDRDTTLAILAG
CCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCEECCCCCEEEEEE
FAHNRRVMISGYHGTGKSSHIEQVAARLNWPCVRINLDSHVSRIDLVGKDAIVVKDGLQV
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEE
TEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLESSGRLTLLDQSRVIRPHPAFR
EECCCCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEE
LFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDHEVNIVAAKVKSFGKDR
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEHHCCCCCCCEEEEEEEHHHCCCCC
EGRDTVSKMVRVADLTRAAFMNGDLSTVMSPRTVITWAENAEIFGDLAFAFRVTFLNKCD
CCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
ELERPLVAEHYQRAFGVELKESAANIVLGA
HHCCCHHHHHHHHHHCCEEHHCCCCEEECC
>Mature Secondary Structure 
SKIDLDISELPDTTVSVREAFGIDSDIRVPAYSKGDAYVPDLDTDYLFDRDTTLAILAG
CCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCEECCCCCEEEEEE
FAHNRRVMISGYHGTGKSSHIEQVAARLNWPCVRINLDSHVSRIDLVGKDAIVVKDGLQV
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEE
TEFKDGILPWAYQHNVALVFDEYDAGRPDVMFVIQRVLESSGRLTLLDQSRVIRPHPAFR
EECCCCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEE
LFATANTIGLGDTTGLYHGTQQINQAQMDRWSIVTTLNYLPHDHEVNIVAAKVKSFGKDR
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEHHCCCCCCCEEEEEEEHHHCCCCC
EGRDTVSKMVRVADLTRAAFMNGDLSTVMSPRTVITWAENAEIFGDLAFAFRVTFLNKCD
CCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHH
ELERPLVAEHYQRAFGVELKESAANIVLGA
HHCCCHHHHHHHHHHCCEEHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]