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The map label for this gene is cobT [H]

Identifier: 209551166

GI number: 209551166

Start: 3715209

End: 3717110

Strand: Reverse

Name: cobT [H]

Synonym: Rleg2_3590

Alternate gene names: 209551166

Gene position: 3717110-3715209 (Counterclockwise)

Preceding gene: 209551167

Following gene: 209551165

Centisome position: 81.91

GC content: 65.35

Gene sequence:

>1902_bases
ATGGCAGCTCGCGGTGACAATTCGAAAGCAAAGCCCGGCGCGCCCGTCGACGTCGAGCCATTGCGCCGGGCGATATCCGG
CTGCGTGCGCTCGGTCGCCGGCGACGGCGATGTCGAGGTGACCTTCGCCAATGAACGGCCTGGCATGACCGGCGAGCGCA
TCCGGCTGCCGGAGCTTTCCAAGCGGCCGACGGCGCATGAGCTGGCGGTCACCCGCGGGCTCGGCGATTCCATGGCGCTG
CGCCTTGCCTGCCATGACGAGAAGATGCATGCGACGATGGCGCCGCAGGGTTCGGATGCCCGGGCGATCTTCGATGTCGT
CGAGCAGGCGCGCGTCGAATCGATCGGCGCGCTGCGCATGGAGGGCATGGCGACCAACCTGCGCTCCATGACCGAAGAGA
AATATTCCAAGGCGAACTTCACCGGCATCGAGCGCCAGGAAGACGCACCGGTCGGCGAAGCCGTCGCGATGATGGTGCGC
GAGAAGCTCACCGGTCAGCGCCCGCCTGAAACCGCCGGCAAGGTGCTCGACCTCTGGCGCGGCTTCATCGAGGAAAAGGC
GGGGGCCGAACTCAACAATCTGTCGGGTGCGATCAACGACCAGCAGGCCTTCGCCAAGGTCATCCGCAACATGCTGTCGG
CCATGGAAATGGCCGAGGAATACGGCGATGACGACAACGACGCCGACAATGACGACCAGTCGGATCAGGAAGACCAGCCG
AGCGGCGACGAGCAGGATCAGGACGAGGTCGACGAGGATGCCGGCACCGATGCCGCCCCGGTCGAAGACAGCGAAGTCGC
CGACGAGCAGATGGAGGACGGCGAGACCGAAGGCGCCGAAATCTCCGACGACGACATGATGGAAGAGGGCGAGGACGATT
CGGAAACGCCGGGCGAGACCCGCCGTCCGAACACGCCTTTCTCAGATTTCAACGAGAAGGTCGATTATCACGTCTTTACC
GAAGAGTTCGACGAGATCATCACCGCCGAGGAACTCTGCGACGCCGCCGAACTGGAGCGCCTGCGCGCCTTCCTCGACAA
GCAGCTGGCACACCTGCAGGGCGCGGTCGGCCGCCTCGCCAACCGGCTGCAGCGCCGGCTGATGGCGCAGCAGAACCGCT
CCTGGGATTTCGATCTGGAAGAGGGTTATCTCGATCCGGCCCGGCTGCAGCGCATCATCATCGATCCGATGCAGGCGCTG
TCCTTCAAGATGGAGCGCGACACGCAGTTCCGCGACACGGTCGTCACCTTGCTGATCGACAATTCCGGCTCGATGCGCGG
CCGGCCGATCACGGTTGCCGCCACCTGCGCCGATATCCTCGCCCGCACGCTGGAGCGCTGCGGCGTCAAGGTCGAGATCC
TCGGTTTTACCACCAAGGCCTGGAAGGGCGGGCAGGCGCGGGAAAGCTGGCTTGCCGGCGGCAAACCGCAGACGCCCGGC
CGCCTCAACGACCTGCGCCACATCATCTACAAATCGGCCGACGCGCCGTGGCGTCGGGCACGCGCCAATCTCGGGCTGAT
GATGCGCGAGGGCCTGCTCAAGGAAAATATCGACGGCGAGGCGCTGATCTGGGCGCATAACCGCCTGCTCGCACGCCGCG
AGCAGCGCCGCATCCTGATGATGATCTCGGACGGCGCGCCAGTCGACGATTCGACGCTGTCGGTCAATCCGGGCAATTAT
CTCGAGCGGCACCTGCGCGCCGTCATCGAACAGATCGAGACACGCTCGCCGGTGGAATTGCTGGCAATCGGCATCGGTCA
CGACGTGACGCGCTACTATCGCCGCGCCGTGACGATCGTCGATGCCGACGAACTTGCCGGCGCGATGACCGAGCAGCTCG
CCTCGCTGTTCGAAGATCAATCCACCCAGCCGCGTGGCGGCCGGCTCCGTCGTGCCGGCTGA

Upstream 100 bases:

>100_bases
GGAGCGTCCTCTGGTCGCCGAGCACTATCAGCGGGCCTTCGGCGTCGAGCTGAAGGAAAGTGCCGCCAATATCGTTCTCG
GAGCCTGAGACCGACCGATC

Downstream 100 bases:

>100_bases
CGCCGCTGGAAGGAATCGCCCGGAATGACCGTCAGGCGCCTCTGCCGCCTGGCGGCGATCGTCCTCAGCATCGCCGCCGC
AGGCGCTTCCCCCTCATGGG

Product: cobalt chelatase, pCobT subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MAARGDNSKAKPGAPVDVEPLRRAISGCVRSVAGDGDVEVTFANERPGMTGERIRLPELSKRPTAHELAVTRGLGDSMAL
RLACHDEKMHATMAPQGSDARAIFDVVEQARVESIGALRMEGMATNLRSMTEEKYSKANFTGIERQEDAPVGEAVAMMVR
EKLTGQRPPETAGKVLDLWRGFIEEKAGAELNNLSGAINDQQAFAKVIRNMLSAMEMAEEYGDDDNDADNDDQSDQEDQP
SGDEQDQDEVDEDAGTDAAPVEDSEVADEQMEDGETEGAEISDDDMMEEGEDDSETPGETRRPNTPFSDFNEKVDYHVFT
EEFDEIITAEELCDAAELERLRAFLDKQLAHLQGAVGRLANRLQRRLMAQQNRSWDFDLEEGYLDPARLQRIIIDPMQAL
SFKMERDTQFRDTVVTLLIDNSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTKAWKGGQARESWLAGGKPQTPG
RLNDLRHIIYKSADAPWRRARANLGLMMREGLLKENIDGEALIWAHNRLLARREQRRILMMISDGAPVDDSTLSVNPGNY
LERHLRAVIEQIETRSPVELLAIGIGHDVTRYYRRAVTIVDADELAGAMTEQLASLFEDQSTQPRGGRLRRAG

Sequences:

>Translated_633_residues
MAARGDNSKAKPGAPVDVEPLRRAISGCVRSVAGDGDVEVTFANERPGMTGERIRLPELSKRPTAHELAVTRGLGDSMAL
RLACHDEKMHATMAPQGSDARAIFDVVEQARVESIGALRMEGMATNLRSMTEEKYSKANFTGIERQEDAPVGEAVAMMVR
EKLTGQRPPETAGKVLDLWRGFIEEKAGAELNNLSGAINDQQAFAKVIRNMLSAMEMAEEYGDDDNDADNDDQSDQEDQP
SGDEQDQDEVDEDAGTDAAPVEDSEVADEQMEDGETEGAEISDDDMMEEGEDDSETPGETRRPNTPFSDFNEKVDYHVFT
EEFDEIITAEELCDAAELERLRAFLDKQLAHLQGAVGRLANRLQRRLMAQQNRSWDFDLEEGYLDPARLQRIIIDPMQAL
SFKMERDTQFRDTVVTLLIDNSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTKAWKGGQARESWLAGGKPQTPG
RLNDLRHIIYKSADAPWRRARANLGLMMREGLLKENIDGEALIWAHNRLLARREQRRILMMISDGAPVDDSTLSVNPGNY
LERHLRAVIEQIETRSPVELLAIGIGHDVTRYYRRAVTIVDADELAGAMTEQLASLFEDQSTQPRGGRLRRAG
>Mature_632_residues
AARGDNSKAKPGAPVDVEPLRRAISGCVRSVAGDGDVEVTFANERPGMTGERIRLPELSKRPTAHELAVTRGLGDSMALR
LACHDEKMHATMAPQGSDARAIFDVVEQARVESIGALRMEGMATNLRSMTEEKYSKANFTGIERQEDAPVGEAVAMMVRE
KLTGQRPPETAGKVLDLWRGFIEEKAGAELNNLSGAINDQQAFAKVIRNMLSAMEMAEEYGDDDNDADNDDQSDQEDQPS
GDEQDQDEVDEDAGTDAAPVEDSEVADEQMEDGETEGAEISDDDMMEEGEDDSETPGETRRPNTPFSDFNEKVDYHVFTE
EFDEIITAEELCDAAELERLRAFLDKQLAHLQGAVGRLANRLQRRLMAQQNRSWDFDLEEGYLDPARLQRIIIDPMQALS
FKMERDTQFRDTVVTLLIDNSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTKAWKGGQARESWLAGGKPQTPGR
LNDLRHIIYKSADAPWRRARANLGLMMREGLLKENIDGEALIWAHNRLLARREQRRILMMISDGAPVDDSTLSVNPGNYL
ERHLRAVIEQIETRSPVELLAIGIGHDVTRYYRRAVTIVDADELAGAMTEQLASLFEDQSTQPRGGRLRRAG

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG4547

COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006538
- InterPro:   IPR002035 [H]

Pfam domain/function: PF06213 CobT [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 70291; Mature: 70160

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARGDNSKAKPGAPVDVEPLRRAISGCVRSVAGDGDVEVTFANERPGMTGERIRLPELS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEECCCCC
KRPTAHELAVTRGLGDSMALRLACHDEKMHATMAPQGSDARAIFDVVEQARVESIGALRM
CCCCHHHHHHHHCCCCCCEEEEEECCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
EGMATNLRSMTEEKYSKANFTGIERQEDAPVGEAVAMMVREKLTGQRPPETAGKVLDLWR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GFIEEKAGAELNNLSGAINDQQAFAKVIRNMLSAMEMAEEYGDDDNDADNDDQSDQEDQP
HHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SGDEQDQDEVDEDAGTDAAPVEDSEVADEQMEDGETEGAEISDDDMMEEGEDDSETPGET
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCC
RRPNTPFSDFNEKVDYHVFTEEFDEIITAEELCDAAELERLRAFLDKQLAHLQGAVGRLA
CCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
NRLQRRLMAQQNRSWDFDLEEGYLDPARLQRIIIDPMQALSFKMERDTQFRDTVVTLLID
HHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEEEC
NSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTKAWKGGQARESWLAGGKPQTPG
CCCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCCHHHHHHCCCCCCCCC
RLNDLRHIIYKSADAPWRRARANLGLMMREGLLKENIDGEALIWAHNRLLARREQRRILM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCEEEE
MISDGAPVDDSTLSVNPGNYLERHLRAVIEQIETRSPVELLAIGIGHDVTRYYRRAVTIV
EEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHEEE
DADELAGAMTEQLASLFEDQSTQPRGGRLRRAG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AARGDNSKAKPGAPVDVEPLRRAISGCVRSVAGDGDVEVTFANERPGMTGERIRLPELS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEECCCCC
KRPTAHELAVTRGLGDSMALRLACHDEKMHATMAPQGSDARAIFDVVEQARVESIGALRM
CCCCHHHHHHHHCCCCCCEEEEEECCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
EGMATNLRSMTEEKYSKANFTGIERQEDAPVGEAVAMMVREKLTGQRPPETAGKVLDLWR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GFIEEKAGAELNNLSGAINDQQAFAKVIRNMLSAMEMAEEYGDDDNDADNDDQSDQEDQP
HHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SGDEQDQDEVDEDAGTDAAPVEDSEVADEQMEDGETEGAEISDDDMMEEGEDDSETPGET
CCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCC
RRPNTPFSDFNEKVDYHVFTEEFDEIITAEELCDAAELERLRAFLDKQLAHLQGAVGRLA
CCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
NRLQRRLMAQQNRSWDFDLEEGYLDPARLQRIIIDPMQALSFKMERDTQFRDTVVTLLID
HHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEEEC
NSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTKAWKGGQARESWLAGGKPQTPG
CCCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEHHCCCCCCHHHHHHCCCCCCCCC
RLNDLRHIIYKSADAPWRRARANLGLMMREGLLKENIDGEALIWAHNRLLARREQRRILM
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCEEEE
MISDGAPVDDSTLSVNPGNYLERHLRAVIEQIETRSPVELLAIGIGHDVTRYYRRAVTIV
EEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCHHEEEECCCHHHHHHHHHHHEEE
DADELAGAMTEQLASLFEDQSTQPRGGRLRRAG
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]