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The map label for this gene is etfA [H]

Identifier: 209551138

GI number: 209551138

Start: 3689792

End: 3690721

Strand: Direct

Name: etfA [H]

Synonym: Rleg2_3562

Alternate gene names: 209551138

Gene position: 3689792-3690721 (Clockwise)

Preceding gene: 209551137

Following gene: 209551139

Centisome position: 81.31

GC content: 63.12

Gene sequence:

>930_bases
ATGACCATTCTTCTTCTGGCCGACCACGACAATGTCAGCCTCTCCGACCAGACCGCCAAGGCGCTGACGGCAGCAAGCCA
GATCGGTTCCGATATCCATGTGCTGGTGGCCGGCAAGGGCGCCAAGGCTGCGGCCGATGCGGCTGCCAAGCTCTCCGGCG
TCTCCAAGGTGCTGCTCGCCGAAAGCGACGCGCTTGCCAATAACCTGGCCGAACCGCTTGCCGACCTGATCGTCTCGCTG
GCCGGCTCTTATGACACCATCGTCTCGGCCGCAACCTCGGTCGGCAAGAACGTGCTTCCGCGCGTCGCTGCCTTGCTTGA
TGTCGCCCAGGTCTCCGAGATCATCGAGGTGATCTCATCCGATACCTTCAAGCGGCCGATCTATGCCGGCAATGCCATCC
AGACGGTACAATCAAGCGATGCCAAGAAGGTCATCACCGTGCGCACCGCTTCCTTTGCCTCGGCAGCCGAAGGCGGCTCC
GCCAGCGTTGAAGCGATCCCGGCGGTCTCCGATCCCGGCCTGTCGCGTTTCGTCAAGGACGCGCTGTCGGCCTCCGACCG
GCCCGAGCTGACTTCGGCGAAGATCATCCTTTCCGGCGGCCGGGCACTCGGCTCGGCGGAAAAATTCAAGGAAGTCATCC
TGCCGCTTGCCGACAAGCTCGGTGCTGCCGTCGGTGCAAGCCGCGCGGCCGTCGATGCCGGTTATGCGCCGAACGACTGG
CAGGTCGGCCAGACCGGCAAGGTCGTCGCCCCGCAGCTCTATATCGCTGCCGGCATCTCGGGTGCCATCCAGCATCTGGC
CGGCATGAAGGATAGCAAGGTGATCGTCGCGATTAACAAGGACGAGGAGGCGCCGATCTTCCAGGTTGCCGACTATGGCC
TGGTCGCCGATCTGTTCGAAGCCCTGCCGGAATTGGAAAAGGCGCTTTAA

Upstream 100 bases:

>100_bases
GCCGCAAGGCCGGCGTCAAGGTCAAGTCGGTCGCCGAACTGATCGACAGACTGAAGAACGAAGCCGGCGTGCTTTAAGCC
AGGAAAGAGAGAACACCATC

Downstream 100 bases:

>100_bases
AACAGGTCGCGCAAAGACCGAAAGCGCGAGAAGCGAATCCGAAAGATCACGACGCGCTTCAAACGCCTCAAATGCTTTTC
TTTCGCACTTGCGAATGACT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTILLLADHDNVSLSDQTAKALTAASQIGSDIHVLVAGKGAKAAADAAAKLSGVSKVLLAESDALANNLAEPLADLIVSL
AGSYDTIVSAATSVGKNVLPRVAALLDVAQVSEIIEVISSDTFKRPIYAGNAIQTVQSSDAKKVITVRTASFASAAEGGS
ASVEAIPAVSDPGLSRFVKDALSASDRPELTSAKIILSGGRALGSAEKFKEVILPLADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEALPELEKAL

Sequences:

>Translated_309_residues
MTILLLADHDNVSLSDQTAKALTAASQIGSDIHVLVAGKGAKAAADAAAKLSGVSKVLLAESDALANNLAEPLADLIVSL
AGSYDTIVSAATSVGKNVLPRVAALLDVAQVSEIIEVISSDTFKRPIYAGNAIQTVQSSDAKKVITVRTASFASAAEGGS
ASVEAIPAVSDPGLSRFVKDALSASDRPELTSAKIILSGGRALGSAEKFKEVILPLADKLGAAVGASRAAVDAGYAPNDW
QVGQTGKVVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEALPELEKAL
>Mature_308_residues
TILLLADHDNVSLSDQTAKALTAASQIGSDIHVLVAGKGAKAAADAAAKLSGVSKVLLAESDALANNLAEPLADLIVSLA
GSYDTIVSAATSVGKNVLPRVAALLDVAQVSEIIEVISSDTFKRPIYAGNAIQTVQSSDAKKVITVRTASFASAAEGGSA
SVEAIPAVSDPGLSRFVKDALSASDRPELTSAKIILSGGRALGSAEKFKEVILPLADKLGAAVGASRAAVDAGYAPNDWQ
VGQTGKVVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFEALPELEKAL

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=54.6623794212219, Blast_Score=315, Evalue=3e-86,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=57.0909090909091, Blast_Score=291, Evalue=8e-79,
Organism=Escherichia coli, GI1786226, Length=199, Percent_Identity=36.1809045226131, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787990, Length=299, Percent_Identity=29.0969899665552, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87082157, Length=255, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=311, Percent_Identity=54.6623794212219, Blast_Score=322, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6325261, Length=316, Percent_Identity=45.8860759493671, Blast_Score=254, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=58.4664536741214, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=58.4664536741214, Blast_Score=329, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31453; Mature: 31322

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILLLADHDNVSLSDQTAKALTAASQIGSDIHVLVAGKGAKAAADAAAKLSGVSKVLLA
CEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
ESDALANNLAEPLADLIVSLAGSYDTIVSAATSVGKNVLPRVAALLDVAQVSEIIEVISS
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DTFKRPIYAGNAIQTVQSSDAKKVITVRTASFASAAEGGSASVEAIPAVSDPGLSRFVKD
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCEEEECCCCCCHHHHHHHH
ALSASDRPELTSAKIILSGGRALGSAEKFKEVILPLADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCHHHHHHCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHH
ALPELEKAL
HHHHHHHCC
>Mature Secondary Structure 
TILLLADHDNVSLSDQTAKALTAASQIGSDIHVLVAGKGAKAAADAAAKLSGVSKVLLA
EEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
ESDALANNLAEPLADLIVSLAGSYDTIVSAATSVGKNVLPRVAALLDVAQVSEIIEVISS
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DTFKRPIYAGNAIQTVQSSDAKKVITVRTASFASAAEGGSASVEAIPAVSDPGLSRFVKD
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCEEEECCCCCCHHHHHHHH
ALSASDRPELTSAKIILSGGRALGSAEKFKEVILPLADKLGAAVGASRAAVDAGYAPNDW
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
QVGQTGKVVAPQLYIAAGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFE
CCCCCCCEECCHHHHHHCHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHH
ALPELEKAL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8599534; 12597275 [H]