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The map label for this gene is pgm [H]

Identifier: 209550927

GI number: 209550927

Start: 3457973

End: 3459604

Strand: Direct

Name: pgm [H]

Synonym: Rleg2_3351

Alternate gene names: 209550927

Gene position: 3457973-3459604 (Clockwise)

Preceding gene: 209550926

Following gene: 209550928

Centisome position: 76.2

GC content: 61.83

Gene sequence:

>1632_bases
ATGAACAAGTCCGTACCCACCACGCCCTATCTGGACCAGAAACCCGGCACGTCGGGTCTGCGCAAGAAGGTTCCGGTCTT
CCAGCAGCCGAATTATGCCGAGAACTTCATCCAGTCGATCTTCGATTCGCTGGAAGGCTATCAGGGCAAGTGCCTCGTCA
TCGGCGGCGACGGACGCTACTACAATCGCGAAGTCATCCAGAAGGCGATCAAGATGGCCGCCGCCAACGGCTTCGGCAAG
GTCATGGTCGGCAAGGGCGGCATCCTGTCGACGCCGGCCGCATCCCACATCATCCGCAAGTACAAGGCTTTCGGCGGCAT
CATTCTCTCCGCCAGCCACAATCCCGGCGGCCCGACCGAAGACTTCGGCATCAAATACAACATCAACAATGGCGGCCCGG
CGCCGGAAAAGATCACCGACGCGATGTATGCGCGCTCGAAGACGATCGACAGCTACAAGATCGCCGATTTCGCCGACGTC
AATCTCGACCGCATCGGCAAGGACGAACTGCCGGGCGGCATGATCCTCTCGGTCATCGACCCGGTCGAGGACTATGCCGC
GCTGATGGAAGAGCTGTTCGATTTCGGCGCCATCCGCAACCTGATCAGCCTCGGCTTCCGCATTGCCTTCGACGGGATGA
GCGCCGTCACCGGCCCATATGCCAAGGAAATCTTCGAAAATCGCCTCGGCGCTCCCCTGGGTTCGGTGCGCAATTTCATG
CCGCTGCCGGATTTCGGCGGTCATCACCCGGACCCGAATCCGGTTCACTGCAAGGAACTCTTCGATGAGATGATGGGCGA
TGACGCGCCCGATTTCGGTGCTGCTTCCGACGGCGACGGCGACCGCAATCTGATCATCGGCCGCGGCATTTTCGTCACCC
CTTCCGACAGCCTGGCAATCCTTGCCGCCAACGCCAATCTTGCTCCCGGTTATTCCGGCGGCCTGGCCGGCATCGCCCGC
TCGATGCCGACATCGGGTGCCGCCGACCGCGTCGCCGAAAAGCGCGGCATCGGCATGTACGAAACGCCGACCGGCTGGAA
ATTCTTCGGCAATCTACTCGACGCCGGCATGGCGACGATCTGCGGTGAGGAAAGCTCCGGCACCGGCTCCAGTCACGTCC
GCGAAAAGGACGGCCTCTGGGCGGTGCTGCTCTGGCTGAACATCCTTGCCGTGCGCGGCGAAAGCGTTGCCGATATCGTC
ACCCAGCACTGGCAGACCTATGGCCGCAACTATTATTCGCGCCATGACTATGAAGGCCTCGACACCGATGCGGCGAACGG
CCTGGTCGACAATCTCCGCAGCCAGCTTTCCACCCTGCCCGGCAAGAGCTTCGGCAGCCTGAAGGTCGAAAAGGCCGACG
ACTTCGCCTATCATGACCCGATCGACAAATCGGTGAGCGAGCATCAGGGTGTCCGCGTGCTCTTTGCGGGCGGCTCCCGC
GTCGTCTTCCGCCTGTCCGGCACCGGCACGTCTGGCGCAACCTTGCGTGTCTATATCGAGCGCTACGAGCCGGATTCGAC
TCGCCACAATATCGAAACGCAGGAAGCGCTCGCCGATCTGATCGCCGCCGCCGAAAGCATTGCCAGCATTCGTGAACGCA
CGGGACGCGACGCGCCAACCGTGATCACCTGA

Upstream 100 bases:

>100_bases
GCAAAAGCAAGGCATGAAATCGGATGTCTCCTGGGAGAAGAGCGCCGAACGCTACGCTGCCCTCTATTCAAGCCTCGTCT
CGAAAGGCATGTGAACTAAA

Downstream 100 bases:

>100_bases
TCCGGGGGGAACATGCGGGGAGAGAGTTCGGCGCAAAGCGGCGCGATCGTCTTCGAGACCGGCGTCGAATTTGCCGTGTG
GTCGCATCACGCCGCACAGA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MNKSVPTTPYLDQKPGTSGLRKKVPVFQQPNYAENFIQSIFDSLEGYQGKCLVIGGDGRYYNREVIQKAIKMAAANGFGK
VMVGKGGILSTPAASHIIRKYKAFGGIILSASHNPGGPTEDFGIKYNINNGGPAPEKITDAMYARSKTIDSYKIADFADV
NLDRIGKDELPGGMILSVIDPVEDYAALMEELFDFGAIRNLISLGFRIAFDGMSAVTGPYAKEIFENRLGAPLGSVRNFM
PLPDFGGHHPDPNPVHCKELFDEMMGDDAPDFGAASDGDGDRNLIIGRGIFVTPSDSLAILAANANLAPGYSGGLAGIAR
SMPTSGAADRVAEKRGIGMYETPTGWKFFGNLLDAGMATICGEESSGTGSSHVREKDGLWAVLLWLNILAVRGESVADIV
TQHWQTYGRNYYSRHDYEGLDTDAANGLVDNLRSQLSTLPGKSFGSLKVEKADDFAYHDPIDKSVSEHQGVRVLFAGGSR
VVFRLSGTGTSGATLRVYIERYEPDSTRHNIETQEALADLIAAAESIASIRERTGRDAPTVIT

Sequences:

>Translated_543_residues
MNKSVPTTPYLDQKPGTSGLRKKVPVFQQPNYAENFIQSIFDSLEGYQGKCLVIGGDGRYYNREVIQKAIKMAAANGFGK
VMVGKGGILSTPAASHIIRKYKAFGGIILSASHNPGGPTEDFGIKYNINNGGPAPEKITDAMYARSKTIDSYKIADFADV
NLDRIGKDELPGGMILSVIDPVEDYAALMEELFDFGAIRNLISLGFRIAFDGMSAVTGPYAKEIFENRLGAPLGSVRNFM
PLPDFGGHHPDPNPVHCKELFDEMMGDDAPDFGAASDGDGDRNLIIGRGIFVTPSDSLAILAANANLAPGYSGGLAGIAR
SMPTSGAADRVAEKRGIGMYETPTGWKFFGNLLDAGMATICGEESSGTGSSHVREKDGLWAVLLWLNILAVRGESVADIV
TQHWQTYGRNYYSRHDYEGLDTDAANGLVDNLRSQLSTLPGKSFGSLKVEKADDFAYHDPIDKSVSEHQGVRVLFAGGSR
VVFRLSGTGTSGATLRVYIERYEPDSTRHNIETQEALADLIAAAESIASIRERTGRDAPTVIT
>Mature_543_residues
MNKSVPTTPYLDQKPGTSGLRKKVPVFQQPNYAENFIQSIFDSLEGYQGKCLVIGGDGRYYNREVIQKAIKMAAANGFGK
VMVGKGGILSTPAASHIIRKYKAFGGIILSASHNPGGPTEDFGIKYNINNGGPAPEKITDAMYARSKTIDSYKIADFADV
NLDRIGKDELPGGMILSVIDPVEDYAALMEELFDFGAIRNLISLGFRIAFDGMSAVTGPYAKEIFENRLGAPLGSVRNFM
PLPDFGGHHPDPNPVHCKELFDEMMGDDAPDFGAASDGDGDRNLIIGRGIFVTPSDSLAILAANANLAPGYSGGLAGIAR
SMPTSGAADRVAEKRGIGMYETPTGWKFFGNLLDAGMATICGEESSGTGSSHVREKDGLWAVLLWLNILAVRGESVADIV
TQHWQTYGRNYYSRHDYEGLDTDAANGLVDNLRSQLSTLPGKSFGSLKVEKADDFAYHDPIDKSVSEHQGVRVLFAGGSR
VVFRLSGTGTSGATLRVYIERYEPDSTRHNIETQEALADLIAAAESIASIRERTGRDAPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=555, Percent_Identity=54.0540540540541, Blast_Score=592, Evalue=1e-169,
Organism=Homo sapiens, GI21361621, Length=558, Percent_Identity=53.763440860215, Blast_Score=591, Evalue=1e-169,
Organism=Homo sapiens, GI133922562, Length=559, Percent_Identity=48.3005366726297, Blast_Score=521, Evalue=1e-148,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=53.0054644808743, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI239741729, Length=132, Percent_Identity=50, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI239743670, Length=132, Percent_Identity=47.7272727272727, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI1786904, Length=422, Percent_Identity=26.5402843601896, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17535441, Length=561, Percent_Identity=49.9108734402852, Blast_Score=538, Evalue=1e-153,
Organism=Saccharomyces cerevisiae, GI6323752, Length=568, Percent_Identity=48.943661971831, Blast_Score=529, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6322722, Length=567, Percent_Identity=47.4426807760141, Blast_Score=501, Evalue=1e-142,
Organism=Drosophila melanogaster, GI17864244, Length=560, Percent_Identity=49.6428571428571, Blast_Score=537, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58455; Mature: 58455

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSVPTTPYLDQKPGTSGLRKKVPVFQQPNYAENFIQSIFDSLEGYQGKCLVIGGDGRY
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
YNREVIQKAIKMAAANGFGKVMVGKGGILSTPAASHIIRKYKAFGGIILSASHNPGGPTE
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCC
DFGIKYNINNGGPAPEKITDAMYARSKTIDSYKIADFADVNLDRIGKDELPGGMILSVID
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCHHHCCCCCCCCCEEEHHHC
PVEDYAALMEELFDFGAIRNLISLGFRIAFDGMSAVTGPYAKEIFENRLGAPLGSVRNFM
CHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCHHHHHHHHHHHCCCHHHHHHCC
PLPDFGGHHPDPNPVHCKELFDEMMGDDAPDFGAASDGDGDRNLIIGRGIFVTPSDSLAI
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCEEE
LAANANLAPGYSGGLAGIARSMPTSGAADRVAEKRGIGMYETPTGWKFFGNLLDAGMATI
EEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
CGEESSGTGSSHVREKDGLWAVLLWLNILAVRGESVADIVTQHWQTYGRNYYSRHDYEGL
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DTDAANGLVDNLRSQLSTLPGKSFGSLKVEKADDFAYHDPIDKSVSEHQGVRVLFAGGSR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCE
VVFRLSGTGTSGATLRVYIERYEPDSTRHNIETQEALADLIAAAESIASIRERTGRDAPT
EEEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VIT
CCC
>Mature Secondary Structure
MNKSVPTTPYLDQKPGTSGLRKKVPVFQQPNYAENFIQSIFDSLEGYQGKCLVIGGDGRY
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
YNREVIQKAIKMAAANGFGKVMVGKGGILSTPAASHIIRKYKAFGGIILSASHNPGGPTE
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCC
DFGIKYNINNGGPAPEKITDAMYARSKTIDSYKIADFADVNLDRIGKDELPGGMILSVID
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCHHHCCCCCCCCCEEEHHHC
PVEDYAALMEELFDFGAIRNLISLGFRIAFDGMSAVTGPYAKEIFENRLGAPLGSVRNFM
CHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCHHHHHHHHHHHCCCHHHHHHCC
PLPDFGGHHPDPNPVHCKELFDEMMGDDAPDFGAASDGDGDRNLIIGRGIFVTPSDSLAI
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCEEE
LAANANLAPGYSGGLAGIARSMPTSGAADRVAEKRGIGMYETPTGWKFFGNLLDAGMATI
EEECCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
CGEESSGTGSSHVREKDGLWAVLLWLNILAVRGESVADIVTQHWQTYGRNYYSRHDYEGL
CCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
DTDAANGLVDNLRSQLSTLPGKSFGSLKVEKADDFAYHDPIDKSVSEHQGVRVLFAGGSR
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCE
VVFRLSGTGTSGATLRVYIERYEPDSTRHNIETQEALADLIAAAESIASIRERTGRDAPT
EEEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
VIT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]