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The map label for this gene is 209550921

Identifier: 209550921

GI number: 209550921

Start: 3448070

End: 3448948

Strand: Direct

Name: 209550921

Synonym: Rleg2_3345

Alternate gene names: NA

Gene position: 3448070-3448948 (Clockwise)

Preceding gene: 209550920

Following gene: 209550922

Centisome position: 75.98

GC content: 63.82

Gene sequence:

>879_bases
ATGCTTTACGATCTTTCGCTGCGCATGGGTTACAGCTACGACGTGCCGGCCTCCGGCGCCCGCCACATCATGCGCCTGAT
GCCGCTGTCGCTGACCAACCGGCAGCGCCTGGTCGCCGGCTCGATCACCATTTCGCCGACGCCGGACGAGCAGTCGCATT
TCGTCGATTTCTTCGATCATCCCGCCACCGCCTTTATGCTGCGCGCGCCGCACGAGACGCTCGACATTCGCATGCAGGCC
CGCGTGCAAGTGGAAAGCCAGCCGATCGCCGCCGATTTTTCGCCGCTGCTCGCCGACTTGCCGGAGGAATTGTCAGGCGT
CTGGTCGCTGGCGCCGGATTCGCCGCACCACTTTCTCGGCGACAGCCCGCGCCTGACGCAGGCGCGTGAAATCGCCGACT
ATGCCCGAAGCTGCGCCATGCCCGATCTGACGGCGATGCAGATCGCCTACGCGATCTGTGCCCGCATCTACAAGGATTTC
ACCTACGATGCCGACGCGACGACAGTCGACACGACGCCGCTTGAGGCATTCAGGCTGAAGCGCGGCGTCTGCCAGGATTT
CACCCACATCATGATCCTGGGGCTCCGAAGCCTCGGCATCCCGGCCGGCTATGTCTCCGGTTTCCTGCGCACTATCCCGC
CGCCGGGCAAGGAACGCCTCGAAGGGGCGGATGCCATGCATGCCTGGGTCAGGGTCTGGTGCGGCGAGACCATCGGCTGG
ATCGAACTCGACCCGACCAACAACATCCCCGCTGGCACCGATCACATCGTCGTCGCCTATGGCCGCGACTATTCCGACGT
CGTTCCCGTCATCGGCGTATTGAAAAGCTATGGCGGCCAGCGCGCCGTCCAGGCGGTTGATGTGATCCCGCTGAAATAA

Upstream 100 bases:

>100_bases
TGACGCCGGAGGGCATGGGGGCCGAGGTCTATCAGCGCCTCGAACGCGAATTGGAGCAGCTTTCCGATCTGCTCGCCCAG
ACCTATCTCGGGTGACGGCG

Downstream 100 bases:

>100_bases
TCCCAAAACTGGAAAAATCCTCGGGTTCGTTAAAATTCTATTGACGCTGTAAGGCAGGCGTAAAGAAGCAGCGTGCGTTA
ATCACCTCATAGGGTTTCCA

Product: transglutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLYDLSLRMGYSYDVPASGARHIMRLMPLSLTNRQRLVAGSITISPTPDEQSHFVDFFDHPATAFMLRAPHETLDIRMQA
RVQVESQPIAADFSPLLADLPEELSGVWSLAPDSPHHFLGDSPRLTQAREIADYARSCAMPDLTAMQIAYAICARIYKDF
TYDADATTVDTTPLEAFRLKRGVCQDFTHIMILGLRSLGIPAGYVSGFLRTIPPPGKERLEGADAMHAWVRVWCGETIGW
IELDPTNNIPAGTDHIVVAYGRDYSDVVPVIGVLKSYGGQRAVQAVDVIPLK

Sequences:

>Translated_292_residues
MLYDLSLRMGYSYDVPASGARHIMRLMPLSLTNRQRLVAGSITISPTPDEQSHFVDFFDHPATAFMLRAPHETLDIRMQA
RVQVESQPIAADFSPLLADLPEELSGVWSLAPDSPHHFLGDSPRLTQAREIADYARSCAMPDLTAMQIAYAICARIYKDF
TYDADATTVDTTPLEAFRLKRGVCQDFTHIMILGLRSLGIPAGYVSGFLRTIPPPGKERLEGADAMHAWVRVWCGETIGW
IELDPTNNIPAGTDHIVVAYGRDYSDVVPVIGVLKSYGGQRAVQAVDVIPLK
>Mature_292_residues
MLYDLSLRMGYSYDVPASGARHIMRLMPLSLTNRQRLVAGSITISPTPDEQSHFVDFFDHPATAFMLRAPHETLDIRMQA
RVQVESQPIAADFSPLLADLPEELSGVWSLAPDSPHHFLGDSPRLTQAREIADYARSCAMPDLTAMQIAYAICARIYKDF
TYDADATTVDTTPLEAFRLKRGVCQDFTHIMILGLRSLGIPAGYVSGFLRTIPPPGKERLEGADAMHAWVRVWCGETIGW
IELDPTNNIPAGTDHIVVAYGRDYSDVVPVIGVLKSYGGQRAVQAVDVIPLK

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0607 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013589
- InterPro:   IPR002931 [H]

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core [H]

EC number: NA

Molecular weight: Translated: 32271; Mature: 32271

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDLSLRMGYSYDVPASGARHIMRLMPLSLTNRQRLVAGSITISPTPDEQSHFVDFFDH
CEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCC
PATAFMLRAPHETLDIRMQARVQVESQPIAADFSPLLADLPEELSGVWSLAPDSPHHFLG
CCCEEEEECCCHHEEEEEEEEEEECCCCCCCCHHHHHHHCHHHHHHEEECCCCCCHHHCC
DSPRLTQAREIADYARSCAMPDLTAMQIAYAICARIYKDFTYDADATTVDTTPLEAFRLK
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHH
RGVCQDFTHIMILGLRSLGIPAGYVSGFLRTIPPPGKERLEGADAMHAWVRVWCGETIGW
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCCCCE
IELDPTNNIPAGTDHIVVAYGRDYSDVVPVIGVLKSYGGQRAVQAVDVIPLK
EEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHEEEECCC
>Mature Secondary Structure
MLYDLSLRMGYSYDVPASGARHIMRLMPLSLTNRQRLVAGSITISPTPDEQSHFVDFFDH
CEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHCC
PATAFMLRAPHETLDIRMQARVQVESQPIAADFSPLLADLPEELSGVWSLAPDSPHHFLG
CCCEEEEECCCHHEEEEEEEEEEECCCCCCCCHHHHHHHCHHHHHHEEECCCCCCHHHCC
DSPRLTQAREIADYARSCAMPDLTAMQIAYAICARIYKDFTYDADATTVDTTPLEAFRLK
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHH
RGVCQDFTHIMILGLRSLGIPAGYVSGFLRTIPPPGKERLEGADAMHAWVRVWCGETIGW
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHCCCCCE
IELDPTNNIPAGTDHIVVAYGRDYSDVVPVIGVLKSYGGQRAVQAVDVIPLK
EEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]