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The map label for this gene is phoP [H]

Identifier: 209550841

GI number: 209550841

Start: 3357177

End: 3357545

Strand: Reverse

Name: phoP [H]

Synonym: Rleg2_3265

Alternate gene names: 209550841

Gene position: 3357545-3357177 (Counterclockwise)

Preceding gene: 209550842

Following gene: 209550840

Centisome position: 73.99

GC content: 61.79

Gene sequence:

>369_bases
ATGAGTGCAAATATCCTGACTGTCGACGATTCCGCCAGCATCCGCCTGACCACCAAGGTCACGCTAAGCAATGCCGGTTA
CAGCGTCACCGAAGCCGCCGACGGGGCCGAAGGCCTGGCGACGGCCAAGGGTGGCCGCTTCGATCTGATCGTGACCGATC
TCAATATGCCGGTCATGGACGGCCTGACGATGATCGAGGAGCTGCGGAAACTGCCCGGGCAGGCCGGCGTCCCGATCATC
TTCCTGACGACGGAATCGGATACGGATCTCAAGGCGCGCGCCAAGGCCGCCGGCGCGACGGGTTGGCTGACCAAGCCGTT
CGATCCCGAACATCTCGTGAAGATCGTGAAGAAGGTTCTCGGACGATGA

Upstream 100 bases:

>100_bases
CTGCTCGCGGCTCGGTGCTGAAGGTACTTGAACGCGCAGGTTTCATTGAAACCTTCGATCAAGAAGATGCAAGTTTCTGG
TTGCATAAAGAGGTAAAGTT

Downstream 100 bases:

>100_bases
GCACGCTCGATCCCGTTGCCGTGTTCCGCATGGAGGCTGCCGAATGCCTTGAAGCGATCGAGGCCGGTCTTCTCGACCTC
ACTCACCAGCTCGACAACAA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MSANILTVDDSASIRLTTKVTLSNAGYSVTEAADGAEGLATAKGGRFDLIVTDLNMPVMDGLTMIEELRKLPGQAGVPII
FLTTESDTDLKARAKAAGATGWLTKPFDPEHLVKIVKKVLGR

Sequences:

>Translated_122_residues
MSANILTVDDSASIRLTTKVTLSNAGYSVTEAADGAEGLATAKGGRFDLIVTDLNMPVMDGLTMIEELRKLPGQAGVPII
FLTTESDTDLKARAKAAGATGWLTKPFDPEHLVKIVKKVLGR
>Mature_121_residues
SANILTVDDSASIRLTTKVTLSNAGYSVTEAADGAEGLATAKGGRFDLIVTDLNMPVMDGLTMIEELRKLPGQAGVPIIF
LTTESDTDLKARAKAAGATGWLTKPFDPEHLVKIVKKVLGR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=32.7586206896552, Blast_Score=71, Evalue=2e-14,
Organism=Escherichia coli, GI1788905, Length=118, Percent_Identity=34.7457627118644, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1790863, Length=122, Percent_Identity=34.4262295081967, Blast_Score=69, Evalue=6e-14,
Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=30.327868852459, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1786911, Length=104, Percent_Identity=37.5, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=30.2521008403361, Blast_Score=63, Evalue=7e-12,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=30.5084745762712, Blast_Score=62, Evalue=8e-12,
Organism=Escherichia coli, GI87082012, Length=116, Percent_Identity=31.8965517241379, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=104, Percent_Identity=34.6153846153846, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 12900; Mature: 12769

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANILTVDDSASIRLTTKVTLSNAGYSVTEAADGAEGLATAKGGRFDLIVTDLNMPVMD
CCCCEEEECCCCEEEEEEEEEECCCCCEEECCCCCCCCCEECCCCEEEEEEEECCCCHHH
GLTMIEELRKLPGQAGVPIIFLTTESDTDLKARAKAAGATGWLTKPFDPEHLVKIVKKVL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
GR
CC
>Mature Secondary Structure 
SANILTVDDSASIRLTTKVTLSNAGYSVTEAADGAEGLATAKGGRFDLIVTDLNMPVMD
CCCEEEECCCCEEEEEEEEEECCCCCEEECCCCCCCCCEECCCCEEEEEEEECCCCHHH
GLTMIEELRKLPGQAGVPIIFLTTESDTDLKARAKAAGATGWLTKPFDPEHLVKIVKKVL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]