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The map label for this gene is cheA [H]

Identifier: 209550840

GI number: 209550840

Start: 3355141

End: 3357180

Strand: Reverse

Name: cheA [H]

Synonym: Rleg2_3264

Alternate gene names: 209550840

Gene position: 3357180-3355141 (Counterclockwise)

Preceding gene: 209550841

Following gene: 209550839

Centisome position: 73.98

GC content: 65.93

Gene sequence:

>2040_bases
ATGAGCACGCTCGATCCCGTTGCCGTGTTCCGCATGGAGGCTGCCGAATGCCTTGAAGCGATCGAGGCCGGTCTTCTCGA
CCTCACTCACCAGCTCGACAACAAGGATCTCGTCGACGCCGTGTTCCGCGGGCTTCACACGCTCAAGGGCTCCGGCGCGA
TGTTCGGTTTCGAGGCGCTCGCCGCGTTCACCCATCATTGCGAAACCGCCTTCGACCGCGTCCGCAAGGGCGAGGTCGCC
GCGACCAGCGAACTCGTCGCCGCCGTGCTTGCCGCCCAGGACCATATGCGCGCCCTCGTCGACCAGCCGGACGCCGATCA
CGGCGACACCGGCAGCAAGCTTCTGGCGCAGCTGCAGGCTGCCGTCGGCGGCAAGCCGGCAGCGCCTGCTGCCGCACCGG
CCGCTGTTGCCGCACCCGCGGTCGTGCGTGAAGTGTCGGCCAAGAAGAAAAACAGCTGGCGCATCCGCTTCAGCCTGCCA
GCCAACTCGATGGCCAACGGCACCAACCCGCTCGGCCTGCTGGACGAGCTGCGCGACCTCGGCGAATGCACCGTGCGCGC
CAACACCTCGGCCATTCCGCCTCTTAGCGAGCTCACGCCGACGGAACTCCATATTTCCTGGGACGTGATGCTGACCAGCG
AGCAGGACCGCTCGGCGATCGACGACGTTTTCATCTTCGTGCTCGACGATATGGAACTCAGCGTCGAGGAGATCGACGGG
CCGGCGACGGTAAATGTTGCTCCGATTGAGCAAAAGGCAGCACCTCTCCCCGTCGCCGCGGTCTCTGCGGCTGTTCCCGA
GTTTCGTCCCGTCGAGGCGGTGCCGGCGAGGCGCGAGCCGCCCGCCGCCGTCAGCCAGGCGAAGGCGGCAGAGAATGTCC
GCGTTCCGGCCGAGCGTCTCGACGAGCTGATGGACCGCGTCGGCGAGCTCGTCATCGCCCAGTCGCGTCTCAGCCAGCTT
GCCAGCGCCAGCGCCGATATCGCGCTGCGCTCCGTCTCGGAAGAAATCGAACGCCTGTCCGGTGAATTGCGCGACACGAT
GATGGTGCTGCGCATGGTGCCGGTCGCAACCCTCTTCTCCCGTTTCCGCCGCCTCGTCCACGATCTCGCCCGCGAAACCG
GCAAGGTGATCGAGCTGGTGACGGAGGGCGAGAGCACCGAAGTCGACAAGACGGTCATCGAGCGGCTGGCCGATCCGCTG
GTGCATCTGGTGCGCAATTCGATCGATCATGGCCTCGAAATGCCTGCCGACCGCCTTGCCGCCGGCAAGACCCAAGCCGG
CACGGTGACGCTTTCGGCCCGTCAGGCCGGTGGCGAGGTGATCATCTCGATCAAGGACGACGGCCGCGGCATCAATCGCG
AACGGGTTCGCGCCAAGGCGGAATCCTCCGGCCTTATCCACCCCGGCCAGCCACTGTCCGATCCCGAGCTGCTGCAGTTG
ATCTTCGCTCCCGGCTTCTCGACGGCCGCGGCAATCACCAACCTGTCCGGCCGCGGCGTCGGTATGGACGTGGTCAAGAA
GACGGTCGAAGCGCTTCGCGGCGCGATCGACATCGTCAGCGTGCCGGGACAGGGCTCGGAAGTGTCGCTGCGCATCCCGC
TGACGCTTGCCATCATCGACGGCCTGCTGGTGCGTGTCGGTTCCGGCCGTTACGTCATCCCGCTCTCGGCGGTCGAGGAA
TGCCTCGAACTTTCGCTCGAGGAAGATCTTCGCTCGCGCGGCCGCAGCTTCATCTCGCTGCGCGACAGCCTGGTGCCGTT
CCTGCGCCTGCGCGACCTCTTCCGCACCGGCACCAAACCCGACGTCCACCAGAAGGTCGTCGTCATCTCCACAGGCACGG
AGCGCGTCGGCCTCGTCGTCGACCAGATCATCGGCGACCACCAGACGGTCATCAAGTCGATGTCGAAACTGCATAACGAC
GTCGCGACCTTCTCGGGCGCGACCATTCTCGGCGACGGCAGCGTCGCTCTCATTCTCGACGTCGGGCACCTAGTTGCCGC
GGGTCAGCAACAGGAGGCGCAATTGCGGGTAGCAGGATGA

Upstream 100 bases:

>100_bases
ATCTCAAGGCGCGCGCCAAGGCCGCCGGCGCGACGGGTTGGCTGACCAAGCCGTTCGATCCCGAACATCTCGTGAAGATC
GTGAAGAAGGTTCTCGGACG

Downstream 100 bases:

>100_bases
GCGCAACAGCAGCGACAGCCGAACGATTCGACAATCATTGGAGCTTTGCCGAGGAAGTCGAGGTGCTGACCTTCGATCTC
AACGGCGAGACCTTCGCGCT

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MSTLDPVAVFRMEAAECLEAIEAGLLDLTHQLDNKDLVDAVFRGLHTLKGSGAMFGFEALAAFTHHCETAFDRVRKGEVA
ATSELVAAVLAAQDHMRALVDQPDADHGDTGSKLLAQLQAAVGGKPAAPAAAPAAVAAPAVVREVSAKKKNSWRIRFSLP
ANSMANGTNPLGLLDELRDLGECTVRANTSAIPPLSELTPTELHISWDVMLTSEQDRSAIDDVFIFVLDDMELSVEEIDG
PATVNVAPIEQKAAPLPVAAVSAAVPEFRPVEAVPARREPPAAVSQAKAAENVRVPAERLDELMDRVGELVIAQSRLSQL
ASASADIALRSVSEEIERLSGELRDTMMVLRMVPVATLFSRFRRLVHDLARETGKVIELVTEGESTEVDKTVIERLADPL
VHLVRNSIDHGLEMPADRLAAGKTQAGTVTLSARQAGGEVIISIKDDGRGINRERVRAKAESSGLIHPGQPLSDPELLQL
IFAPGFSTAAAITNLSGRGVGMDVVKKTVEALRGAIDIVSVPGQGSEVSLRIPLTLAIIDGLLVRVGSGRYVIPLSAVEE
CLELSLEEDLRSRGRSFISLRDSLVPFLRLRDLFRTGTKPDVHQKVVVISTGTERVGLVVDQIIGDHQTVIKSMSKLHND
VATFSGATILGDGSVALILDVGHLVAAGQQQEAQLRVAG

Sequences:

>Translated_679_residues
MSTLDPVAVFRMEAAECLEAIEAGLLDLTHQLDNKDLVDAVFRGLHTLKGSGAMFGFEALAAFTHHCETAFDRVRKGEVA
ATSELVAAVLAAQDHMRALVDQPDADHGDTGSKLLAQLQAAVGGKPAAPAAAPAAVAAPAVVREVSAKKKNSWRIRFSLP
ANSMANGTNPLGLLDELRDLGECTVRANTSAIPPLSELTPTELHISWDVMLTSEQDRSAIDDVFIFVLDDMELSVEEIDG
PATVNVAPIEQKAAPLPVAAVSAAVPEFRPVEAVPARREPPAAVSQAKAAENVRVPAERLDELMDRVGELVIAQSRLSQL
ASASADIALRSVSEEIERLSGELRDTMMVLRMVPVATLFSRFRRLVHDLARETGKVIELVTEGESTEVDKTVIERLADPL
VHLVRNSIDHGLEMPADRLAAGKTQAGTVTLSARQAGGEVIISIKDDGRGINRERVRAKAESSGLIHPGQPLSDPELLQL
IFAPGFSTAAAITNLSGRGVGMDVVKKTVEALRGAIDIVSVPGQGSEVSLRIPLTLAIIDGLLVRVGSGRYVIPLSAVEE
CLELSLEEDLRSRGRSFISLRDSLVPFLRLRDLFRTGTKPDVHQKVVVISTGTERVGLVVDQIIGDHQTVIKSMSKLHND
VATFSGATILGDGSVALILDVGHLVAAGQQQEAQLRVAG
>Mature_678_residues
STLDPVAVFRMEAAECLEAIEAGLLDLTHQLDNKDLVDAVFRGLHTLKGSGAMFGFEALAAFTHHCETAFDRVRKGEVAA
TSELVAAVLAAQDHMRALVDQPDADHGDTGSKLLAQLQAAVGGKPAAPAAAPAAVAAPAVVREVSAKKKNSWRIRFSLPA
NSMANGTNPLGLLDELRDLGECTVRANTSAIPPLSELTPTELHISWDVMLTSEQDRSAIDDVFIFVLDDMELSVEEIDGP
ATVNVAPIEQKAAPLPVAAVSAAVPEFRPVEAVPARREPPAAVSQAKAAENVRVPAERLDELMDRVGELVIAQSRLSQLA
SASADIALRSVSEEIERLSGELRDTMMVLRMVPVATLFSRFRRLVHDLARETGKVIELVTEGESTEVDKTVIERLADPLV
HLVRNSIDHGLEMPADRLAAGKTQAGTVTLSARQAGGEVIISIKDDGRGINRERVRAKAESSGLIHPGQPLSDPELLQLI
FAPGFSTAAAITNLSGRGVGMDVVKKTVEALRGAIDIVSVPGQGSEVSLRIPLTLAIIDGLLVRVGSGRYVIPLSAVEEC
LELSLEEDLRSRGRSFISLRDSLVPFLRLRDLFRTGTKPDVHQKVVVISTGTERVGLVVDQIIGDHQTVIKSMSKLHNDV
ATFSGATILGDGSVALILDVGHLVAAGQQQEAQLRVAG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=686, Percent_Identity=37.3177842565598, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72380; Mature: 72249

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS51061 R3H ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLDPVAVFRMEAAECLEAIEAGLLDLTHQLDNKDLVDAVFRGLHTLKGSGAMFGFEAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
AAFTHHCETAFDRVRKGEVAATSELVAAVLAAQDHMRALVDQPDADHGDTGSKLLAQLQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AVGGKPAAPAAAPAAVAAPAVVREVSAKKKNSWRIRFSLPANSMANGTNPLGLLDELRDL
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
GECTVRANTSAIPPLSELTPTELHISWDVMLTSEQDRSAIDDVFIFVLDDMELSVEEIDG
HCEEEECCCCCCCCHHHCCCCEEEEEEEEEEECCCHHHHHHHEEEEEECCCCCHHHHCCC
PATVNVAPIEQKAAPLPVAAVSAAVPEFRPVEAVPARREPPAAVSQAKAAENVRVPAERL
CCEEEEECCHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHH
DELMDRVGELVIAQSRLSQLASASADIALRSVSEEIERLSGELRDTMMVLRMVPVATLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFRRLVHDLARETGKVIELVTEGESTEVDKTVIERLADPLVHLVRNSIDHGLEMPADRLA
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AGKTQAGTVTLSARQAGGEVIISIKDDGRGINRERVRAKAESSGLIHPGQPLSDPELLQL
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHH
IFAPGFSTAAAITNLSGRGVGMDVVKKTVEALRGAIDIVSVPGQGSEVSLRIPLTLAIID
HHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCHHHHHHH
GLLVRVGSGRYVIPLSAVEECLELSLEEDLRSRGRSFISLRDSLVPFLRLRDLFRTGTKP
HHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DVHQKVVVISTGTERVGLVVDQIIGDHQTVIKSMSKLHNDVATFSGATILGDGSVALILD
CCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEE
VGHLVAAGQQQEAQLRVAG
HHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
STLDPVAVFRMEAAECLEAIEAGLLDLTHQLDNKDLVDAVFRGLHTLKGSGAMFGFEAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
AAFTHHCETAFDRVRKGEVAATSELVAAVLAAQDHMRALVDQPDADHGDTGSKLLAQLQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AVGGKPAAPAAAPAAVAAPAVVREVSAKKKNSWRIRFSLPANSMANGTNPLGLLDELRDL
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
GECTVRANTSAIPPLSELTPTELHISWDVMLTSEQDRSAIDDVFIFVLDDMELSVEEIDG
HCEEEECCCCCCCCHHHCCCCEEEEEEEEEEECCCHHHHHHHEEEEEECCCCCHHHHCCC
PATVNVAPIEQKAAPLPVAAVSAAVPEFRPVEAVPARREPPAAVSQAKAAENVRVPAERL
CCEEEEECCHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHH
DELMDRVGELVIAQSRLSQLASASADIALRSVSEEIERLSGELRDTMMVLRMVPVATLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFRRLVHDLARETGKVIELVTEGESTEVDKTVIERLADPLVHLVRNSIDHGLEMPADRLA
HHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
AGKTQAGTVTLSARQAGGEVIISIKDDGRGINRERVRAKAESSGLIHPGQPLSDPELLQL
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHH
IFAPGFSTAAAITNLSGRGVGMDVVKKTVEALRGAIDIVSVPGQGSEVSLRIPLTLAIID
HHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCHHHHHHH
GLLVRVGSGRYVIPLSAVEECLELSLEEDLRSRGRSFISLRDSLVPFLRLRDLFRTGTKP
HHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
DVHQKVVVISTGTERVGLVVDQIIGDHQTVIKSMSKLHNDVATFSGATILGDGSVALILD
CCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEE
VGHLVAAGQQQEAQLRVAG
HHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]