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The map label for this gene is ruvC [H]

Identifier: 209550793

GI number: 209550793

Start: 3306180

End: 3306689

Strand: Direct

Name: ruvC [H]

Synonym: Rleg2_3217

Alternate gene names: 209550793

Gene position: 3306180-3306689 (Clockwise)

Preceding gene: 209550790

Following gene: 209550794

Centisome position: 72.86

GC content: 61.57

Gene sequence:

>510_bases
ATGCAAAATACGATTCGCATCGTCGGCATCGATCCCGGCCTTCGCCGCACCGGCTGGGGAATCATCGACACACTTGGCAA
TTCCCTGCGCTTTGTCGCCTCCGGAACCGTGACCTCCGACGGAGACATGGACCTTGCCTCTCGCCTCTGCCAGTTGCATG
ACGGGCTGGCGGAGGTCGTCCACACTTACAAGCCGGATGAAGCCGCCGTCGAACAGACCTTCGTCAACAAGGATGCGGTG
GCGACCCTGAAGCTTGGCCAGGCTCGCGGCATCGCCATGCTGGTGCCGGCGCGCGCCGGACTACGGGTCTCCGAATATGC
TCCGAACGCCGTGAAGAAGGCCGTCATCGGCGTCGGCCACGGCGAAAAACACCAGATCCACATGATGTTGAAGATCCTGA
TGCCGAAGGTCGAATTCAAAGGCGATGACGCTGCCGACGCCCTGGCGATCGCCATTTGCCATGCCCACAATCGTGGCAGC
AACCGGATGCGGGAAGCACTGGCCGGCTAA

Upstream 100 bases:

>100_bases
TGTTTTAATTCGCGGTAAATGGAGCGGCTTAAATCCGAGAATGTTTTTGTTTTGTTCACATATCGGTGGCAGTTATTTCG
CAGTCGCTATAGGTTGAACC

Downstream 100 bases:

>100_bases
TCTGTTCTTGACTTGTTCCGACAGTAAGGATAATTCTTACTTCGAAGGAACAGCAAGATGCGCGTCACGTCCAAAGGCCA
GGTCACCATTCCTCGCGATC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVVHTYKPDEAAVEQTFVNKDAV
ATLKLGQARGIAMLVPARAGLRVSEYAPNAVKKAVIGVGHGEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGS
NRMREALAG

Sequences:

>Translated_169_residues
MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVVHTYKPDEAAVEQTFVNKDAV
ATLKLGQARGIAMLVPARAGLRVSEYAPNAVKKAVIGVGHGEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGS
NRMREALAG
>Mature_169_residues
MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVVHTYKPDEAAVEQTFVNKDAV
ATLKLGQARGIAMLVPARAGLRVSEYAPNAVKKAVIGVGHGEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGS
NRMREALAG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=128, Percent_Identity=42.96875, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18104; Mature: 18104

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVV
CCCCEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
HTYKPDEAAVEQTFVNKDAVATLKLGQARGIAMLVPARAGLRVSEYAPNAVKKAVIGVGH
HHCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCEEHHCCCHHHHHHHHCCCC
GEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGSNRMREALAG
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVV
CCCCEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
HTYKPDEAAVEQTFVNKDAVATLKLGQARGIAMLVPARAGLRVSEYAPNAVKKAVIGVGH
HHCCCCHHHHHHHHCCCCCEEEEEECCCCCEEEEECCCCCCEEHHCCCHHHHHHHHCCCC
GEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGSNRMREALAG
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA