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The map label for this gene is yciR [C]

Identifier: 209550753

GI number: 209550753

Start: 3260237

End: 3261808

Strand: Direct

Name: yciR [C]

Synonym: Rleg2_3177

Alternate gene names: 209550753

Gene position: 3260237-3261808 (Clockwise)

Preceding gene: 209550752

Following gene: 209550755

Centisome position: 71.84

GC content: 60.81

Gene sequence:

>1572_bases
ATGCCGGTGTTTTTCCAGAGCAGGGCCGGAAGGCAATGCGTATCGATCGTCGGGCTTGGGATAACTCTCTGGCTCCTCGG
CGCGCTTTTGCAGCTTGACGACAGCCTTGTCTTCTTCATGACCGGTTTCGGCGAATATGGTGCCGACAAACTCGTTCTGG
CTCTCGGCATCGCCGGCGCCATGAGCTTCATCTATTCGGTGCTGCGCATCGCCGACCTGCGCAAGGAAACGGAACTGCGC
GCCGCCGCCCAGGCGAAGGCCGATTGGACCGCAACTCACGACCATCTGACCAAGCTGCCGAACCGCTACGCCTTCGAACG
CAAGATCCTGTCACGGCCGATCAAGGACGACGAGGACCAGGTCGAGGAGTGGGACCAGAACGTCACGCTTTTCTCCGTCG
ATCTTGACGGCTTCAAGAAAGTCAACGATCTCGTCGGCCACAAGGGCGGCGATATTCTGCTCATCGAGGTTGCCAGAAGG
ATCTGCGCGCTCGGCAATGCCGATTGCGTCTATCGCTTCGGCGGCGACGAATTCATCATTGTCGCCTTTGCCCTGACGGC
GCAGCGCGAGGAGCGTTTTGCCAAATTGTTGATCCAGGCGGTCACCCGGCCGATCCATATCGATGGTTTTGCCGTCGAAG
TCGGCGCCAGCGTCGGCTACGACCGCTGGGCCGAGGGAACCGAACCGCTGGAGGATGCCGCTCATCGGGCCGACCTCGCC
ATGTACGAGGCGAAATCACGCGGCCCCAACCATTATTTGGTTTTCGAACCGGCTATGCAGGACAAAGTTGCGGAACGCGC
TGCGCTGGAAACCAGGCTACGTGCCGCAATCTCCAACAAGGCGATCAAACCCTTTTATCAGCCGCTGATCGACCTGAAGA
CCGGGCAGCTCTGCGGCTTCGAGGCGCTGGCGCGCTGGATCGGCGAGGATGGCATCAATATCCCGCCGCCGGTCTTCATC
GATATCGCCGAGGAAACCGGGATGATCACGGCCTTGTTCGAGGATCTTCTCGCCCAGGCCTGCAGCGACGCGCTCACCTG
GCCGGACCATGTGATGCTGTCCTTCAACGTCTCGCCGGTACAGATGGAAGACAGGCTGCTGACGTCGCGCATTCTCAAGG
TGCTTTCGGCAAGCCGGCTGCCGCCGCATCGCCTGGAAGTGGAGATCACCGAAAACGCGTTGATCCAGGATCCGGCCATC
GCCGCCGTCATCCTTGATGAACTGCACGCGGCCGGCATCCAGATCGCGCTCGACGATTTCGGCACGGGTTATTCGAGCCT
GGCCCAGCTCGCCCGCTATCGTTTCGACAAGATCAAGATCGACAAAAGCTTCATCGCCACCTATCGCGGTGACGAACGTC
AGGAAAAGATCGTCCGCGCCATGCTTGGCCTCGGTCGGAGCCTCAACATCAAGACCACCGCTGAGGGTGTCGAGGAGCAC
GGCCAGCTCGCCTTCCTGCTGCAGCTCGGCTGCGACATCGGCCAAGGTTATCTTTTCGGCAAGGCGATGCCCGCCGCCGA
GGCGGGCATCTTCATCAGCGATCGCAATGCCAGTCTGGCCTCCACGGCCTGA

Upstream 100 bases:

>100_bases
CAGCAACAGGCTGCTGTCCCCAAAAATTCGCCTTCTGGTTTCAACGAACATTTCAGACTTTCATGATAGTCCGGCATAGG
GTGGAGATGGAGAAGGCCAT

Downstream 100 bases:

>100_bases
CGCTGCGTTTTTAAAATACCTGGCGCAGGATCACGAAGAGCACGAAGGCGATCGCGATCGATGCCGGCAGCGTCAGCACC
CAGGCCATCAGCATGTTGCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MPVFFQSRAGRQCVSIVGLGITLWLLGALLQLDDSLVFFMTGFGEYGADKLVLALGIAGAMSFIYSVLRIADLRKETELR
AAAQAKADWTATHDHLTKLPNRYAFERKILSRPIKDDEDQVEEWDQNVTLFSVDLDGFKKVNDLVGHKGGDILLIEVARR
ICALGNADCVYRFGGDEFIIVAFALTAQREERFAKLLIQAVTRPIHIDGFAVEVGASVGYDRWAEGTEPLEDAAHRADLA
MYEAKSRGPNHYLVFEPAMQDKVAERAALETRLRAAISNKAIKPFYQPLIDLKTGQLCGFEALARWIGEDGINIPPPVFI
DIAEETGMITALFEDLLAQACSDALTWPDHVMLSFNVSPVQMEDRLLTSRILKVLSASRLPPHRLEVEITENALIQDPAI
AAVILDELHAAGIQIALDDFGTGYSSLAQLARYRFDKIKIDKSFIATYRGDERQEKIVRAMLGLGRSLNIKTTAEGVEEH
GQLAFLLQLGCDIGQGYLFGKAMPAAEAGIFISDRNASLASTA

Sequences:

>Translated_523_residues
MPVFFQSRAGRQCVSIVGLGITLWLLGALLQLDDSLVFFMTGFGEYGADKLVLALGIAGAMSFIYSVLRIADLRKETELR
AAAQAKADWTATHDHLTKLPNRYAFERKILSRPIKDDEDQVEEWDQNVTLFSVDLDGFKKVNDLVGHKGGDILLIEVARR
ICALGNADCVYRFGGDEFIIVAFALTAQREERFAKLLIQAVTRPIHIDGFAVEVGASVGYDRWAEGTEPLEDAAHRADLA
MYEAKSRGPNHYLVFEPAMQDKVAERAALETRLRAAISNKAIKPFYQPLIDLKTGQLCGFEALARWIGEDGINIPPPVFI
DIAEETGMITALFEDLLAQACSDALTWPDHVMLSFNVSPVQMEDRLLTSRILKVLSASRLPPHRLEVEITENALIQDPAI
AAVILDELHAAGIQIALDDFGTGYSSLAQLARYRFDKIKIDKSFIATYRGDERQEKIVRAMLGLGRSLNIKTTAEGVEEH
GQLAFLLQLGCDIGQGYLFGKAMPAAEAGIFISDRNASLASTA
>Mature_522_residues
PVFFQSRAGRQCVSIVGLGITLWLLGALLQLDDSLVFFMTGFGEYGADKLVLALGIAGAMSFIYSVLRIADLRKETELRA
AAQAKADWTATHDHLTKLPNRYAFERKILSRPIKDDEDQVEEWDQNVTLFSVDLDGFKKVNDLVGHKGGDILLIEVARRI
CALGNADCVYRFGGDEFIIVAFALTAQREERFAKLLIQAVTRPIHIDGFAVEVGASVGYDRWAEGTEPLEDAAHRADLAM
YEAKSRGPNHYLVFEPAMQDKVAERAALETRLRAAISNKAIKPFYQPLIDLKTGQLCGFEALARWIGEDGINIPPPVFID
IAEETGMITALFEDLLAQACSDALTWPDHVMLSFNVSPVQMEDRLLTSRILKVLSASRLPPHRLEVEITENALIQDPAIA
AVILDELHAAGIQIALDDFGTGYSSLAQLARYRFDKIKIDKSFIATYRGDERQEKIVRAMLGLGRSLNIKTTAEGVEEHG
QLAFLLQLGCDIGQGYLFGKAMPAAEAGIFISDRNASLASTA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=428, Percent_Identity=34.8130841121495, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI87081921, Length=456, Percent_Identity=30.2631578947368, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI226510982, Length=397, Percent_Identity=27.455919395466, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=35.1694915254237, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787055, Length=515, Percent_Identity=26.4077669902913, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081743, Length=243, Percent_Identity=34.9794238683128, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87081845, Length=243, Percent_Identity=35.8024691358025, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788502, Length=238, Percent_Identity=32.7731092436975, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081980, Length=243, Percent_Identity=32.9218106995885, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1786507, Length=244, Percent_Identity=34.0163934426229, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=485, Percent_Identity=24.3298969072165, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788381, Length=453, Percent_Identity=27.1523178807947, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788849, Length=250, Percent_Identity=29.2, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787410, Length=219, Percent_Identity=29.6803652968037, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788956, Length=180, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=31.1111111111111, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787816, Length=127, Percent_Identity=36.2204724409449, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 57647; Mature: 57516

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVFFQSRAGRQCVSIVGLGITLWLLGALLQLDDSLVFFMTGFGEYGADKLVLALGIAGA
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
MSFIYSVLRIADLRKETELRAAAQAKADWTATHDHLTKLPNRYAFERKILSRPIKDDEDQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHHH
VEEWDQNVTLFSVDLDGFKKVNDLVGHKGGDILLIEVARRICALGNADCVYRFGGDEFII
HHHHCCCEEEEEECCCHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCEEEEECCCEEEE
VAFALTAQREERFAKLLIQAVTRPIHIDGFAVEVGASVGYDRWAEGTEPLEDAAHRADLA
EEEEHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHH
MYEAKSRGPNHYLVFEPAMQDKVAERAALETRLRAAISNKAIKPFYQPLIDLKTGQLCGF
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCH
EALARWIGEDGINIPPPVFIDIAEETGMITALFEDLLAQACSDALTWPDHVMLSFNVSPV
HHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
QMEDRLLTSRILKVLSASRLPPHRLEVEITENALIQDPAIAAVILDELHAAGIQIALDDF
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEECCC
GTGYSSLAQLARYRFDKIKIDKSFIATYRGDERQEKIVRAMLGLGRSLNIKTTAEGVEEH
CCCHHHHHHHHHHHHHHEEECHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHC
GQLAFLLQLGCDIGQGYLFGKAMPAAEAGIFISDRNASLASTA
CCEEEEEHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
PVFFQSRAGRQCVSIVGLGITLWLLGALLQLDDSLVFFMTGFGEYGADKLVLALGIAGA
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
MSFIYSVLRIADLRKETELRAAAQAKADWTATHDHLTKLPNRYAFERKILSRPIKDDEDQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHHH
VEEWDQNVTLFSVDLDGFKKVNDLVGHKGGDILLIEVARRICALGNADCVYRFGGDEFII
HHHHCCCEEEEEECCCHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCCEEEEECCCEEEE
VAFALTAQREERFAKLLIQAVTRPIHIDGFAVEVGASVGYDRWAEGTEPLEDAAHRADLA
EEEEHHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCCCHHCCCCCCHHHHHHHHHHHH
MYEAKSRGPNHYLVFEPAMQDKVAERAALETRLRAAISNKAIKPFYQPLIDLKTGQLCGF
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCH
EALARWIGEDGINIPPPVFIDIAEETGMITALFEDLLAQACSDALTWPDHVMLSFNVSPV
HHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
QMEDRLLTSRILKVLSASRLPPHRLEVEITENALIQDPAIAAVILDELHAAGIQIALDDF
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEECCC
GTGYSSLAQLARYRFDKIKIDKSFIATYRGDERQEKIVRAMLGLGRSLNIKTTAEGVEEH
CCCHHHHHHHHHHHHHHEEECHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHC
GQLAFLLQLGCDIGQGYLFGKAMPAAEAGIFISDRNASLASTA
CCEEEEEHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]