BacMap

Definition	Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome.
Accession	NC_011369
Length	4,537,948

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The map label for this gene is fabG [H]

Identifier: 209550688

GI number: 209550688

Start: 3181789

End: 3182577

Strand: Reverse

Name: fabG [H]

Synonym: Rleg2_3112

Alternate gene names: 209550688

Gene position: 3182577-3181789 (Counterclockwise)

Preceding gene: 209550690

Following gene: 209550687

Centisome position: 70.13

GC content: 63.37

Gene sequence:

>789_bases
ATGGATCTGGGACTGAAGGGAAAGACCGCCGTCATAACAGGCGCGTCTGTCGGGATTGGGTTGGCGATCGCCGAGGGGCT
GGCGGCTGAGGGGTCCAATCTCGTGCTGGCGGCCCGCGGCGGCGAACGGCTCGCGGCGGAGGCCGCCCGTATCGCCGAGA
AGTACGGCGTCAGCGCGGTCGCTGTTGCCGCCGATGTGGCGACGGTTGACGGAACGGAGGCGATCATTGCGGCGGCGGCC
GAAAAAGGCGGCGCCGATATCCTCATCAACAATGCCGGCACCGGATCGAACGAGACGGTGATGGAGGCCCCCGACGAGAA
GTGGCAGAGCTATTGGGATCTGCATGTGATGGCCGCGGTGCGGCTTGCGCGCGGCATCGCCCCGCAGATGAAGAGGCGCG
GTGGCGGCGTGATCCTGCACAATGCCTCGATCTGCGCCGTCCAGCCGCTCTGGTACGAGCCGATTTACAATGTCAGCAAG
TCGGCGCTGATGATGTTTTCGAAGACGCTTTCGACCGAACTCATCCCGGACAATATCCGCGTCAACTGTGTCAATGCCGG
CCTGATCCTCACCCCCGACTGGATCAAGACCGCCAAGCAGTTGACCGCCGAAACCGGCGGGAACTGGGAAGGCTACCTGC
AGAGCGTCGCCAACGAACATGCCGCCTCCAAACGCTTCGGCACACCGGAGGAACTGGCAAACGTCTTCGTCTTCCTGAGC
TCGGAGCGGGCGAGCTATTGCGTCGGCTCGACCTATTTTGTCGACGGCGGCATGCTGAAGACGATCTGA

Upstream 100 bases:

>100_bases
GCCCGCCGCAAGAGGCATCTCAGTGCTTGACGCGCGGTTTCATTGGCGGAACATTCGGCAGATCAGGCCGGAACCGCCGG
CCGCTTGCGCGGAGGAAAAT

Downstream 100 bases:

>100_bases
GTGAAACGACAGCGCTGCGGGTCTCAGACGCGCAGCGCTGTAACACTTTGAATTCAGCGGGAGCGGCATTGCTCGGCAAG
TCGGTTCCAAGACAGCCGGG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MDLGLKGKTAVITGASVGIGLAIAEGLAAEGSNLVLAARGGERLAAEAARIAEKYGVSAVAVAADVATVDGTEAIIAAAA
EKGGADILINNAGTGSNETVMEAPDEKWQSYWDLHVMAAVRLARGIAPQMKRRGGGVILHNASICAVQPLWYEPIYNVSK
SALMMFSKTLSTELIPDNIRVNCVNAGLILTPDWIKTAKQLTAETGGNWEGYLQSVANEHAASKRFGTPEELANVFVFLS
SERASYCVGSTYFVDGGMLKTI

Sequences:

>Translated_262_residues
MDLGLKGKTAVITGASVGIGLAIAEGLAAEGSNLVLAARGGERLAAEAARIAEKYGVSAVAVAADVATVDGTEAIIAAAA
EKGGADILINNAGTGSNETVMEAPDEKWQSYWDLHVMAAVRLARGIAPQMKRRGGGVILHNASICAVQPLWYEPIYNVSK
SALMMFSKTLSTELIPDNIRVNCVNAGLILTPDWIKTAKQLTAETGGNWEGYLQSVANEHAASKRFGTPEELANVFVFLS
SERASYCVGSTYFVDGGMLKTI
>Mature_262_residues
MDLGLKGKTAVITGASVGIGLAIAEGLAAEGSNLVLAARGGERLAAEAARIAEKYGVSAVAVAADVATVDGTEAIIAAAA
EKGGADILINNAGTGSNETVMEAPDEKWQSYWDLHVMAAVRLARGIAPQMKRRGGGVILHNASICAVQPLWYEPIYNVSK
SALMMFSKTLSTELIPDNIRVNCVNAGLILTPDWIKTAKQLTAETGGNWEGYLQSVANEHAASKRFGTPEELANVFVFLS
SERASYCVGSTYFVDGGMLKTI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=33.976833976834, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=32.4427480916031, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=33.0739299610895, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=33.8709677419355, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=34.010152284264, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=27.4131274131274, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=26.1363636363636, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI302344755, Length=107, Percent_Identity=39.2523364485981, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=27.1653543307087, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4557649, Length=197, Percent_Identity=34.5177664974619, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705855, Length=184, Percent_Identity=29.3478260869565, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=30.3191489361702, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI40254992, Length=256, Percent_Identity=27.34375, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=30.0518134715026, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=26.5625, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=254, Percent_Identity=25.1968503937008, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI59889578, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=28.1746031746032, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI226371731, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI223718074, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=30.6201550387597, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=31.1538461538462, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=31.8007662835249, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=30.2681992337165, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=29.5019157088123, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=31.9066147859922, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=29.1338582677165, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=29.296875, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=29.5275590551181, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=27.6243093922652, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786812, Length=263, Percent_Identity=28.1368821292776, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=30.3501945525292, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=30.46875, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=30.188679245283, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.5343511450382, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=31.3492063492063, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=32.5757575757576, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=30.5343511450382, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=32.6996197718631, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.1526717557252, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.4090909090909, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=32.4110671936759, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=29.0697674418605, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=28.7878787878788, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=28.3524904214559, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=27.3764258555133, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=262, Percent_Identity=28.2442748091603, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=29.6703296703297, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=29.1828793774319, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=25.187969924812, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=29.2592592592593, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=26.4925373134328, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=26.7441860465116, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.0566037735849, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=28.8321167883212, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=33.160621761658, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=186, Percent_Identity=26.8817204301075, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=28.4210526315789, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=33.59375, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=30.6201550387597, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=31.5384615384615, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=30.7086614173228, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644339, Length=256, Percent_Identity=29.296875, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=35.0515463917526, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=35.0515463917526, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=26.8482490272374, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI161076933, Length=264, Percent_Identity=31.4393939393939, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=34.2105263157895, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=31.4176245210728, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=30.2325581395349, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357673, Length=223, Percent_Identity=29.5964125560538, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=26.063829787234, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584752, Length=187, Percent_Identity=31.0160427807487, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27476; Mature: 27476

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLKGKTAVITGASVGIGLAIAEGLAAEGSNLVLAARGGERLAAEAARIAEKYGVSAV
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEE
AVAADVATVDGTEAIIAAAAEKGGADILINNAGTGSNETVMEAPDEKWQSYWDLHVMAAV
EEEHHHEECCCCHHHHEECCCCCCCEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHH
RLARGIAPQMKRRGGGVILHNASICAVQPLWYEPIYNVSKSALMMFSKTLSTELIPDNIR
HHHHCCCHHHHHCCCCEEEECCCEEEECCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCEE
VNCVNAGLILTPDWIKTAKQLTAETGGNWEGYLQSVANEHAASKRFGTPEELANVFVFLS
EEEEECCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEEE
SERASYCVGSTYFVDGGMLKTI
CCCCCEEECCEEEECCCEEECC
>Mature Secondary Structure
MDLGLKGKTAVITGASVGIGLAIAEGLAAEGSNLVLAARGGERLAAEAARIAEKYGVSAV
CCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEE
AVAADVATVDGTEAIIAAAAEKGGADILINNAGTGSNETVMEAPDEKWQSYWDLHVMAAV
EEEHHHEECCCCHHHHEECCCCCCCEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHH
RLARGIAPQMKRRGGGVILHNASICAVQPLWYEPIYNVSKSALMMFSKTLSTELIPDNIR
HHHHCCCHHHHHCCCCEEEECCCEEEECCCHHCHHHHHHHHHHHHHHHHHHHCCCCCCEE
VNCVNAGLILTPDWIKTAKQLTAETGGNWEGYLQSVANEHAASKRFGTPEELANVFVFLS
EEEEECCEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHEEEEEEE
SERASYCVGSTYFVDGGMLKTI
CCCCCEEECCEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]