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The map label for this gene is mdtA [H]

Identifier: 209550672

GI number: 209550672

Start: 3163027

End: 3164217

Strand: Reverse

Name: mdtA [H]

Synonym: Rleg2_3096

Alternate gene names: 209550672

Gene position: 3164217-3163027 (Counterclockwise)

Preceding gene: 209550673

Following gene: 209550671

Centisome position: 69.73

GC content: 66.67

Gene sequence:

>1191_bases
ATGACGTCCAGAAGTAAGCGCTGGGCCCTGGTGGGCGCCGGCATGGGCCTTGTTGCGTCCGTTTCAGGCGCCGCATTATT
TTTCGAACTGCCGATGAGCACAACCGCCACGGCTGCTTCCGCTCCGGCGCAGCCGCCTGCCGTGCCGGTGACGGTTGCCG
TCGTCGCGGCGCGCGACGTGACGGCCTGGGAGAGTTTCTCCGGCCGTCTCGAAGCGGTCGACCGTGTCCAGGTTCGTTCC
CGCGTCGCCGGCGCCATCCTATCGGTGGCCTTCCGCGAAGGGGCGCTGGTCAAGCAGGGCGACCTGCTCTTCACCATCGA
CCCGGCTCCCTATCAAGCGAACGTGGCGCAGGCTGAGGGCCAGGTCGCTTCGGCCGAAGCCAAGGTCAGCCTCGCGCAGA
CCGAGCTCGATCGCGGCCGCAGGCTTTCCGATAACCGCACCATCTCCCAGAGCGATCTCGATCAGCGCCACAGCACGCTG
GCCGAGGCGCAGGCGGGGCTGCGTTCGGCGCAGGCCGCATTGCAGTCGGCCCAGCTCGATCTCGACTATACCGAGGTGCG
GGCGCCGGTTTCCGGCCGCATCGGCAAGATCGAGGTGACCGCCGGTAACCTGGTTGCGGCCGGCTCGGCCTCGCCGGCGC
TGACGACGCTCGTTTCGGTCGATCCGATCTATGCGAGCTTCAACGCCAGCGAAGAAATGGTGACACGCGCGCTTGCCGAA
CTTCCGCAGACCGACAGCGCCCTGCCGCCGGTCGAGCAGATCCCGGTCGAGGTCGGCACGCTTGCCGACAGCGGCACGCC
GATCAAAGGCAAGCTGCAGCTGATCGACAATGAGGTCGATGCAGCGAGCGGCACGATCGGCGTGCGCGCCGTCTTCGACA
ATCCGGGCGGCCGTCTCATCCCCGGCCAGTTTGTGCGGGTGCGCATGGGCCAGCCGAAGGCCGAGAACAAGATCGTCATC
AGCGACCGCGCCGTCGGCACCGACCAGGACAAGAAGTTCGTCTTCGTCGTCGATGCCGAAAACAAGGTTGCCTACCGGCA
GGTCCAGCTCGGTACGCTGTCCGACGGCCAGCGGGTGGTCGAAAGCGGCCTGAACGCCGGCGAAAAGATCGTCGTCAACG
GCCTGCAGCGCATTCGTCCGGGCGCGGTCGTCATACCGCAGATGGAAGAGAAGGTCGCGACCGCTCAGTAA

Upstream 100 bases:

>100_bases
GTCATTTCGGAAGCTTCCTTCAGGACGTGAGCGTCCAACCGCAATTGCATTGAAGATGATCTGATATTTCAGCGGCTTTG
GCCGCAAGGAGAGTACTGAT

Downstream 100 bases:

>100_bases
GTCTTCGCTCTCCCCCCGCGGGGGAGGGCCAATACCCGAAATGATATGACCCGCCGGCGGCTCCAACCGCCGGAGAGGGA
CGTTGCATCCATGTTCACCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTSRSKRWALVGAGMGLVASVSGAALFFELPMSTTATAASAPAQPPAVPVTVAVVAARDVTAWESFSGRLEAVDRVQVRS
RVAGAILSVAFREGALVKQGDLLFTIDPAPYQANVAQAEGQVASAEAKVSLAQTELDRGRRLSDNRTISQSDLDQRHSTL
AEAQAGLRSAQAALQSAQLDLDYTEVRAPVSGRIGKIEVTAGNLVAAGSASPALTTLVSVDPIYASFNASEEMVTRALAE
LPQTDSALPPVEQIPVEVGTLADSGTPIKGKLQLIDNEVDAASGTIGVRAVFDNPGGRLIPGQFVRVRMGQPKAENKIVI
SDRAVGTDQDKKFVFVVDAENKVAYRQVQLGTLSDGQRVVESGLNAGEKIVVNGLQRIRPGAVVIPQMEEKVATAQ

Sequences:

>Translated_396_residues
MTSRSKRWALVGAGMGLVASVSGAALFFELPMSTTATAASAPAQPPAVPVTVAVVAARDVTAWESFSGRLEAVDRVQVRS
RVAGAILSVAFREGALVKQGDLLFTIDPAPYQANVAQAEGQVASAEAKVSLAQTELDRGRRLSDNRTISQSDLDQRHSTL
AEAQAGLRSAQAALQSAQLDLDYTEVRAPVSGRIGKIEVTAGNLVAAGSASPALTTLVSVDPIYASFNASEEMVTRALAE
LPQTDSALPPVEQIPVEVGTLADSGTPIKGKLQLIDNEVDAASGTIGVRAVFDNPGGRLIPGQFVRVRMGQPKAENKIVI
SDRAVGTDQDKKFVFVVDAENKVAYRQVQLGTLSDGQRVVESGLNAGEKIVVNGLQRIRPGAVVIPQMEEKVATAQ
>Mature_395_residues
TSRSKRWALVGAGMGLVASVSGAALFFELPMSTTATAASAPAQPPAVPVTVAVVAARDVTAWESFSGRLEAVDRVQVRSR
VAGAILSVAFREGALVKQGDLLFTIDPAPYQANVAQAEGQVASAEAKVSLAQTELDRGRRLSDNRTISQSDLDQRHSTLA
EAQAGLRSAQAALQSAQLDLDYTEVRAPVSGRIGKIEVTAGNLVAAGSASPALTTLVSVDPIYASFNASEEMVTRALAEL
PQTDSALPPVEQIPVEVGTLADSGTPIKGKLQLIDNEVDAASGTIGVRAVFDNPGGRLIPGQFVRVRMGQPKAENKIVIS
DRAVGTDQDKKFVFVVDAENKVAYRQVQLGTLSDGQRVVESGLNAGEKIVVNGLQRIRPGAVVIPQMEEKVATAQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=340, Percent_Identity=33.8235294117647, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1789929, Length=362, Percent_Identity=32.3204419889503, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1789665, Length=340, Percent_Identity=35.2941176470588, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786668, Length=347, Percent_Identity=35.4466858789625, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI87081796, Length=335, Percent_Identity=26.5671641791045, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081951, Length=147, Percent_Identity=36.0544217687075, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789637, Length=133, Percent_Identity=33.8345864661654, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790519, Length=255, Percent_Identity=24.7058823529412, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41530; Mature: 41398

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRSKRWALVGAGMGLVASVSGAALFFELPMSTTATAASAPAQPPAVPVTVAVVAARDV
CCCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCC
TAWESFSGRLEAVDRVQVRSRVAGAILSVAFREGALVKQGDLLFTIDPAPYQANVAQAEG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCHHHCCC
QVASAEAKVSLAQTELDRGRRLSDNRTISQSDLDQRHSTLAEAQAGLRSAQAALQSAQLD
CEECCHHEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDYTEVRAPVSGRIGKIEVTAGNLVAAGSASPALTTLVSVDPIYASFNASEEMVTRALAE
CCHHHHCCCCCCCCEEEEEECCCEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHH
LPQTDSALPPVEQIPVEVGTLADSGTPIKGKLQLIDNEVDAASGTIGVRAVFDNPGGRLI
CCCCCCCCCCHHHCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCEEC
PGQFVRVRMGQPKAENKIVISDRAVGTDQDKKFVFVVDAENKVAYRQVQLGTLSDGQRVV
CCCEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCHHHHH
ESGLNAGEKIVVNGLQRIRPGAVVIPQMEEKVATAQ
HHHCCCCCHHHHHHHHHCCCCEEECCCHHHHHCCCC
>Mature Secondary Structure 
TSRSKRWALVGAGMGLVASVSGAALFFELPMSTTATAASAPAQPPAVPVTVAVVAARDV
CCCCCEEEEEECCCCCEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCC
TAWESFSGRLEAVDRVQVRSRVAGAILSVAFREGALVKQGDLLFTIDPAPYQANVAQAEG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCCHHHCCC
QVASAEAKVSLAQTELDRGRRLSDNRTISQSDLDQRHSTLAEAQAGLRSAQAALQSAQLD
CEECCHHEEEHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LDYTEVRAPVSGRIGKIEVTAGNLVAAGSASPALTTLVSVDPIYASFNASEEMVTRALAE
CCHHHHCCCCCCCCEEEEEECCCEEECCCCCCCEEEEEECCCEEECCCCHHHHHHHHHHH
LPQTDSALPPVEQIPVEVGTLADSGTPIKGKLQLIDNEVDAASGTIGVRAVFDNPGGRLI
CCCCCCCCCCHHHCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCEEC
PGQFVRVRMGQPKAENKIVISDRAVGTDQDKKFVFVVDAENKVAYRQVQLGTLSDGQRVV
CCCEEEEECCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCHHHHH
ESGLNAGEKIVVNGLQRIRPGAVVIPQMEEKVATAQ
HHHCCCCCHHHHHHHHHCCCCEEECCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]