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The map label for this gene is aprE [H]

Identifier: 209550553

GI number: 209550553

Start: 3036512

End: 3037819

Strand: Reverse

Name: aprE [H]

Synonym: Rleg2_2977

Alternate gene names: 209550553

Gene position: 3037819-3036512 (Counterclockwise)

Preceding gene: 209550554

Following gene: 209550552

Centisome position: 66.94

GC content: 58.03

Gene sequence:

>1308_bases
GTGAGAAAAGTCATCAGTGAATCCAAACGCTCCCTCAATCGCCATGTCGCTCTTGTTGGCGTGTTGTCGATAGCTCTCGT
TTGCGGCATCGGTGGTTGGGCAGCAACGACTGAGCTGTCGAGCGCCGTCATCGGCGAAGGCGTTGTCGTCGTCAACGGCG
ATGTCAAGAAGGTCCAGCACCTGACAGGCGGTATCGTATCGAAACTGCTGGTCTCCGAAAATGACCATGTGACGGCCGGA
CAGATCCTGATACAGCTCGATGGCACGACGACAAAAGCACAGCTTTCGATCGTCGAAAGCACACTCGCTCAGCTTTATGC
GCGTCGTGCCCGTCTGAAGGCCGAACGGATCGACGCCGAGTCATTCGATGTCGAGGAAAACATCAGCGATCTTACATCCA
GCACGGCGGCGCGGGATCTGCTCGACGGCGAGACGAAATTGTTCGACAGCCGCAGGTCGGCGCTCGTGGGAATGAAAAGC
CAGTTGGCGTCGCGTAAGGATCAGCTGGCCGAGCAGATCAAGGGGTTGGTCGTTCAGATCAACGCTACCAATGATTCCCT
CAGCCTGATCGAACAGGAGCTCGAAGGCGTCGATACGCTCTACAAGAAGGGGCTGGTCACGCTGCAGCGTTTGAATGCAC
TCAAACGCGCCCGCGCCGACCTTCAAGGCAATAGCGGCCAGGAAATCGCTGCAAAGGCGGAGGCCGAAGGCAAGGCAATC
GAGATCGATCGCCAGTCGCTCCAGCTGGACGAGGATCGCCGTTCGGAGATCGCCAAGGAACTGACCGACGTCGAGGCGAA
GATCGCCGAAAATGAAGAGCGCCGCGGAACCGCGCTCGATCAACTCCGCCGTCTCGACATTGTCGCGCCGCTCAGCGGGC
GCATTCACGAGCTTTCCATTCACACGGTCAATGGCGTCGTCAACCCGGGTGAGACCCTGATGCTCGTCGTTCCCGAAAAT
GAAGATCTCACGGTTCAGGCGAGGGTCGCCACGCGCGATATCGATCAGCTTCACGTCGGCCAGTCCGTCGATGTTCGGTT
CAGCGCCTTTGATCAGCGCACAACGCCTGACGTGCGCGGCGAGATCACGTCGATTGCACCCGATGTCGTCAAGGATGAGC
GGACGGGCATCAGCTATTATCCCCTTCGCGTCAAGCCGGAGGCTGAAAGCATCGCCAAGCTGAAGTCGATAAAGCTCTAT
CCCGGCATGCCGGCCGAAGTCTTCATCAAGATCGCCGACAGAAACGTTATCTCCTATCTGACGAAGCCGCTGACCGATCA
GATGCAGCACGTCTTTCGTGAGGAATGA

Upstream 100 bases:

>100_bases
GCAGGAACCGGCGGCGCGCACGCCGATTGCCGATCGCGTGGCTCAGCTCAAGGTCGTGGTCGACGGCATGAATGCGGCTG
AATAGGCCGGAAGGAAGATT

Downstream 100 bases:

>100_bases
TCGGCGCGGCTGTGCCGCGTCACAAGCGGCGTGAGCGGTCATCGTCATGACATTGTCTCAGGCCTGCTGCGGCTTGGTTG
AAGAAGGGCATGGCTGCCCT

Product: type I secretion membrane fusion protein, HlyD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MRKVISESKRSLNRHVALVGVLSIALVCGIGGWAATTELSSAVIGEGVVVVNGDVKKVQHLTGGIVSKLLVSENDHVTAG
QILIQLDGTTTKAQLSIVESTLAQLYARRARLKAERIDAESFDVEENISDLTSSTAARDLLDGETKLFDSRRSALVGMKS
QLASRKDQLAEQIKGLVVQINATNDSLSLIEQELEGVDTLYKKGLVTLQRLNALKRARADLQGNSGQEIAAKAEAEGKAI
EIDRQSLQLDEDRRSEIAKELTDVEAKIAENEERRGTALDQLRRLDIVAPLSGRIHELSIHTVNGVVNPGETLMLVVPEN
EDLTVQARVATRDIDQLHVGQSVDVRFSAFDQRTTPDVRGEITSIAPDVVKDERTGISYYPLRVKPEAESIAKLKSIKLY
PGMPAEVFIKIADRNVISYLTKPLTDQMQHVFREE

Sequences:

>Translated_435_residues
MRKVISESKRSLNRHVALVGVLSIALVCGIGGWAATTELSSAVIGEGVVVVNGDVKKVQHLTGGIVSKLLVSENDHVTAG
QILIQLDGTTTKAQLSIVESTLAQLYARRARLKAERIDAESFDVEENISDLTSSTAARDLLDGETKLFDSRRSALVGMKS
QLASRKDQLAEQIKGLVVQINATNDSLSLIEQELEGVDTLYKKGLVTLQRLNALKRARADLQGNSGQEIAAKAEAEGKAI
EIDRQSLQLDEDRRSEIAKELTDVEAKIAENEERRGTALDQLRRLDIVAPLSGRIHELSIHTVNGVVNPGETLMLVVPEN
EDLTVQARVATRDIDQLHVGQSVDVRFSAFDQRTTPDVRGEITSIAPDVVKDERTGISYYPLRVKPEAESIAKLKSIKLY
PGMPAEVFIKIADRNVISYLTKPLTDQMQHVFREE
>Mature_435_residues
MRKVISESKRSLNRHVALVGVLSIALVCGIGGWAATTELSSAVIGEGVVVVNGDVKKVQHLTGGIVSKLLVSENDHVTAG
QILIQLDGTTTKAQLSIVESTLAQLYARRARLKAERIDAESFDVEENISDLTSSTAARDLLDGETKLFDSRRSALVGMKS
QLASRKDQLAEQIKGLVVQINATNDSLSLIEQELEGVDTLYKKGLVTLQRLNALKRARADLQGNSGQEIAAKAEAEGKAI
EIDRQSLQLDEDRRSEIAKELTDVEAKIAENEERRGTALDQLRRLDIVAPLSGRIHELSIHTVNGVVNPGETLMLVVPEN
EDLTVQARVATRDIDQLHVGQSVDVRFSAFDQRTTPDVRGEITSIAPDVVKDERTGISYYPLRVKPEAESIAKLKSIKLY
PGMPAEVFIKIADRNVISYLTKPLTDQMQHVFREE

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47710; Mature: 47710

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00422 GRANINS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKVISESKRSLNRHVALVGVLSIALVCGIGGWAATTELSSAVIGEGVVVVNGDVKKVQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHH
LTGGIVSKLLVSENDHVTAGQILIQLDGTTTKAQLSIVESTLAQLYARRARLKAERIDAE
HHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFDVEENISDLTSSTAARDLLDGETKLFDSRRSALVGMKSQLASRKDQLAEQIKGLVVQI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
NATNDSLSLIEQELEGVDTLYKKGLVTLQRLNALKRARADLQGNSGQEIAAKAEAEGKAI
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEE
EIDRQSLQLDEDRRSEIAKELTDVEAKIAENEERRGTALDQLRRLDIVAPLSGRIHELSI
EEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCEECCCCCCEEEEEE
HTVNGVVNPGETLMLVVPENEDLTVQARVATRDIDQLHVGQSVDVRFSAFDQRTTPDVRG
EEECCCCCCCCEEEEEEECCCCEEEEEEEHHCCHHHHHCCCCCCEEEECCCCCCCCCCCC
EITSIAPDVVKDERTGISYYPLRVKPEAESIAKLKSIKLYPGMPAEVFIKIADRNVISYL
CHHHCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHEEECCCCCHHEEEEECCCHHHHHH
TKPLTDQMQHVFREE
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKVISESKRSLNRHVALVGVLSIALVCGIGGWAATTELSSAVIGEGVVVVNGDVKKVQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCHHHHHH
LTGGIVSKLLVSENDHVTAGQILIQLDGTTTKAQLSIVESTLAQLYARRARLKAERIDAE
HHHHHHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SFDVEENISDLTSSTAARDLLDGETKLFDSRRSALVGMKSQLASRKDQLAEQIKGLVVQI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
NATNDSLSLIEQELEGVDTLYKKGLVTLQRLNALKRARADLQGNSGQEIAAKAEAEGKAI
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEE
EIDRQSLQLDEDRRSEIAKELTDVEAKIAENEERRGTALDQLRRLDIVAPLSGRIHELSI
EEEHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHCEECCCCCCEEEEEE
HTVNGVVNPGETLMLVVPENEDLTVQARVATRDIDQLHVGQSVDVRFSAFDQRTTPDVRG
EEECCCCCCCCEEEEEEECCCCEEEEEEEHHCCHHHHHCCCCCCEEEECCCCCCCCCCCC
EITSIAPDVVKDERTGISYYPLRVKPEAESIAKLKSIKLYPGMPAEVFIKIADRNVISYL
CHHHCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHEEECCCCCHHEEEEECCCHHHHHH
TKPLTDQMQHVFREE
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]