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The map label for this gene is yogA [H]

Identifier: 209550498

GI number: 209550498

Start: 2977737

End: 2978864

Strand: Reverse

Name: yogA [H]

Synonym: Rleg2_2921

Alternate gene names: 209550498

Gene position: 2978864-2977737 (Counterclockwise)

Preceding gene: 209550501

Following gene: 209550497

Centisome position: 65.64

GC content: 65.16

Gene sequence:

>1128_bases
ATGAACATCGAGACATCAAAGTTGAAACAGGCCTCGCAGAGGCTGCCGGAGCGGATGAAGGGCGTTCTCCTCACCGGCCG
TGGCGGTTTCGAGAAACTGGAATATCGCGAGGACATTCCGCTTCCCCGGCCGAAGGCCGGCGAGGTGCTGATCCGCGTCG
CTGCGGCCGGCGTCAACAACACCGATATCAACACCCGCATCGGCTGGTATTCCAAGACGGTGACAACAGGCACGGAAAGC
GGTGGGGCAACCGGTTTCCAGTCGGTACAGGATGCCGACGCCAGCTGGTCCGGCGTGCCGCTCGCCTTTCCGCGCATCCA
GGGGGCTGATTGTTGCGGGCGCATCGCCGCGGTCGGGGAGGGTGTCGATCCCGGCCGGATCGGCGAGCGGGTGCTGGTGC
GCAATATGCTGCGCTCCTATACCGATTATCGGCCCTTCGAGTGCTGGACCTTCGGCTCGGAATGCGATGGCGGCTTTGCC
CAATATGCGGTGGCGCCGTCGCGCGAGACTTATCGGATCGATTGCGATTGGAGTGATGTCGAACTGGCGTCGCTGCCCTG
CGCCTATTCCACCGCCGAGGGCATGCTGCACCGGGCGGTCGTCGGCGCCGGCGAGCACGTGCTGATCGCCGGCGCTTCGG
GCGGCGTCGGCTCGGCGGCGATCCAGCTGGCGAAACGCCGGGGCGCGATCGTCACGGCGATCTCAAGCCCGGAAAAGGCC
TCGCAATTGCTGGCCATCGGCGCCGACCGCATCCTTTCGCGCGGCGAGAGCATCGTCGCCGGGCTCGGCCACGAGTCGGT
CGACGTCGTGCTCGATGTCGCCGCAGGTCCGTCTTTCGGCGAGCTGCTCGACGTCCTGAAAAAGGGCGGGCGATACGCCG
TTGCCGGCGCCATCGCCGGGCCGCTCGTCGAGCTCGACGTCAGAACCCTCTATCTCAAGGACCTGACCTTCTTCGGCTGC
ACCTTCCAGGAGGACGTGGTTTTCGAAAACCTCGTCTCCTATGTCGAGCGCGGCGAAATCAGGCCGCTCGTCGGCAAAAG
CTACCCCTTGCGCGATATCGTCGAGGCGCAGCGGGATTTCCTGTCGAAGCGCATCGCCGGCAAGCTCGTCCTCGTCATCC
CCGAATAG

Upstream 100 bases:

>100_bases
GCCTGCCTGCCGCTTTCATAGGACCCATCGACAGCCTGTCGCGAGGAGAAGGCGCCTATCGGCGCCTTGGCAAGGCTGTT
TTTCGAGGTCCCAAACAGAC

Downstream 100 bases:

>100_bases
ACGCCATCCCGGAATAAGAAGCAGATGAGCGAACTCAAAATCGAAAAAATCGATGTCTTCCAGGTCGACCTGCCCTATTC
GGGCGGCGTCTACCGCCTGT

Product: alcohol dehydrogenase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNIETSKLKQASQRLPERMKGVLLTGRGGFEKLEYREDIPLPRPKAGEVLIRVAAAGVNNTDINTRIGWYSKTVTTGTES
GGATGFQSVQDADASWSGVPLAFPRIQGADCCGRIAAVGEGVDPGRIGERVLVRNMLRSYTDYRPFECWTFGSECDGGFA
QYAVAPSRETYRIDCDWSDVELASLPCAYSTAEGMLHRAVVGAGEHVLIAGASGGVGSAAIQLAKRRGAIVTAISSPEKA
SQLLAIGADRILSRGESIVAGLGHESVDVVLDVAAGPSFGELLDVLKKGGRYAVAGAIAGPLVELDVRTLYLKDLTFFGC
TFQEDVVFENLVSYVERGEIRPLVGKSYPLRDIVEAQRDFLSKRIAGKLVLVIPE

Sequences:

>Translated_375_residues
MNIETSKLKQASQRLPERMKGVLLTGRGGFEKLEYREDIPLPRPKAGEVLIRVAAAGVNNTDINTRIGWYSKTVTTGTES
GGATGFQSVQDADASWSGVPLAFPRIQGADCCGRIAAVGEGVDPGRIGERVLVRNMLRSYTDYRPFECWTFGSECDGGFA
QYAVAPSRETYRIDCDWSDVELASLPCAYSTAEGMLHRAVVGAGEHVLIAGASGGVGSAAIQLAKRRGAIVTAISSPEKA
SQLLAIGADRILSRGESIVAGLGHESVDVVLDVAAGPSFGELLDVLKKGGRYAVAGAIAGPLVELDVRTLYLKDLTFFGC
TFQEDVVFENLVSYVERGEIRPLVGKSYPLRDIVEAQRDFLSKRIAGKLVLVIPE
>Mature_375_residues
MNIETSKLKQASQRLPERMKGVLLTGRGGFEKLEYREDIPLPRPKAGEVLIRVAAAGVNNTDINTRIGWYSKTVTTGTES
GGATGFQSVQDADASWSGVPLAFPRIQGADCCGRIAAVGEGVDPGRIGERVLVRNMLRSYTDYRPFECWTFGSECDGGFA
QYAVAPSRETYRIDCDWSDVELASLPCAYSTAEGMLHRAVVGAGEHVLIAGASGGVGSAAIQLAKRRGAIVTAISSPEKA
SQLLAIGADRILSRGESIVAGLGHESVDVVLDVAAGPSFGELLDVLKKGGRYAVAGAIAGPLVELDVRTLYLKDLTFFGC
TFQEDVVFENLVSYVERGEIRPLVGKSYPLRDIVEAQRDFLSKRIAGKLVLVIPE

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=369, Percent_Identity=28.4552845528455, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI13236495, Length=369, Percent_Identity=28.4552845528455, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI194239676, Length=364, Percent_Identity=26.6483516483516, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI197927207, Length=192, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787863, Length=360, Percent_Identity=23.8888888888889, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082125, Length=290, Percent_Identity=27.9310344827586, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=370, Percent_Identity=21.8918918918919, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=239, Percent_Identity=30.1255230125523, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=386, Percent_Identity=24.8704663212435, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323729, Length=245, Percent_Identity=27.7551020408163, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=379, Percent_Identity=24.5382585751979, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=243, Percent_Identity=28.3950617283951, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 40143; Mature: 40143

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIETSKLKQASQRLPERMKGVLLTGRGGFEKLEYREDIPLPRPKAGEVLIRVAAAGVNN
CCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCC
TDINTRIGWYSKTVTTGTESGGATGFQSVQDADASWSGVPLAFPRIQGADCCGRIAAVGE
CCCCCEECEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHCC
GVDPGRIGERVLVRNMLRSYTDYRPFECWTFGSECDGGFAQYAVAPSRETYRIDCDWSDV
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCC
ELASLPCAYSTAEGMLHRAVVGAGEHVLIAGASGGVGSAAIQLAKRRGAIVTAISSPEKA
CHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHH
SQLLAIGADRILSRGESIVAGLGHESVDVVLDVAAGPSFGELLDVLKKGGRYAVAGAIAG
HHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHC
PLVELDVRTLYLKDLTFFGCTFQEDVVFENLVSYVERGEIRPLVGKSYPLRDIVEAQRDF
CEEEEHHHEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LSKRIAGKLVLVIPE
HHHHHCCEEEEEECC
>Mature Secondary Structure
MNIETSKLKQASQRLPERMKGVLLTGRGGFEKLEYREDIPLPRPKAGEVLIRVAAAGVNN
CCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCCC
TDINTRIGWYSKTVTTGTESGGATGFQSVQDADASWSGVPLAFPRIQGADCCGRIAAVGE
CCCCCEECEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHCC
GVDPGRIGERVLVRNMLRSYTDYRPFECWTFGSECDGGFAQYAVAPSRETYRIDCDWSDV
CCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCCEEEEECCCCCC
ELASLPCAYSTAEGMLHRAVVGAGEHVLIAGASGGVGSAAIQLAKRRGAIVTAISSPEKA
CHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHH
SQLLAIGADRILSRGESIVAGLGHESVDVVLDVAAGPSFGELLDVLKKGGRYAVAGAIAG
HHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEHHHHC
PLVELDVRTLYLKDLTFFGCTFQEDVVFENLVSYVERGEIRPLVGKSYPLRDIVEAQRDF
CEEEEHHHEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
LSKRIAGKLVLVIPE
HHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]