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The map label for this gene is map [H]

Identifier: 209550432

GI number: 209550432

Start: 2904021

End: 2904779

Strand: Reverse

Name: map [H]

Synonym: Rleg2_2853

Alternate gene names: 209550432

Gene position: 2904779-2904021 (Counterclockwise)

Preceding gene: 209550433

Following gene: 209550430

Centisome position: 64.01

GC content: 65.22

Gene sequence:

>759_bases
ATGGTTATCGCAAACGACGACGAACTGACAAAGCTCAAGGAGATCGGCCGGATCTGCGCCAACGCCATCCAGGTGATGGC
GGCGGCAATGGAGCCCGGCATGACGACGCTGGAGCTCGACCGGATCGGCCGTAAGGTGCTCGAGGATTCGGGCGCGCGCT
CGGCGCCGGAGTTCTGCTACCAGTTTCCGGGGGCGACCTGCATCAGCGTCAATGAGGAAATCGCCCACGGCATTCCCGGG
CCGCGCGTCATCCGCGCCGGCGACCTCGTCAACATCGACGTCTCGGCGGAGAAGGACGGCTTCTTTGCCGATACCGGCGC
TTCCTTCGCGATGCCGCCGGTCAAGCCGAAGATCGACAAGCTCTGCCGCGACGGCAAGCGGGCGCTCTGGGTCGGGCTTA
ACCAGGTGAAATCGGGCGAGCCATTGGCAAAGATCGGCACCGCTGTCGGCGCCTTCGCGCAGAAGAACCGCTATACGCTG
GTCGCCAATCTGGCGAGCCACGGCGTCGGCCGCTCGCTGCACGAGGAGCCGGCCGAACTCTCGACCTGGCCGGACCCTTC
GGAAAAACGCGTCATGACGGATGGGCTCGTCTTTACCGTCGAGCCTTTCCTGTCGCTCGGCGCGACCTGGGCGGAAGGCG
GCGACGATGCGTGGACGCTCTATGCCGATCCGAAGGCGCCGACCGTGCAGTATGAACATACGGTTGTGGCAACGCGCAAC
GGGCCGGTGATTCTGACTTTGCCGGACGGGCGGGCGTAG

Upstream 100 bases:

>100_bases
CGATCGTCAGAAAGGCATTGACTGAAAGCGGCGAAGGGGCGAAAGCCACGGCCTAACCAAGGCGACTAAGCTCGCCCCTG
CGCAAAGCCGGAACAGACGA

Downstream 100 bases:

>100_bases
GGAAGCGCCGCGCCCTTCGAGGATACCCGATGGTTACCGTGATCTGCCGGCGTCTCGACGGCGCATCGTCGGGGACGCTC
ACTTCTCCTCCCTCATTCCT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MVIANDDELTKLKEIGRICANAIQVMAAAMEPGMTTLELDRIGRKVLEDSGARSAPEFCYQFPGATCISVNEEIAHGIPG
PRVIRAGDLVNIDVSAEKDGFFADTGASFAMPPVKPKIDKLCRDGKRALWVGLNQVKSGEPLAKIGTAVGAFAQKNRYTL
VANLASHGVGRSLHEEPAELSTWPDPSEKRVMTDGLVFTVEPFLSLGATWAEGGDDAWTLYADPKAPTVQYEHTVVATRN
GPVILTLPDGRA

Sequences:

>Translated_252_residues
MVIANDDELTKLKEIGRICANAIQVMAAAMEPGMTTLELDRIGRKVLEDSGARSAPEFCYQFPGATCISVNEEIAHGIPG
PRVIRAGDLVNIDVSAEKDGFFADTGASFAMPPVKPKIDKLCRDGKRALWVGLNQVKSGEPLAKIGTAVGAFAQKNRYTL
VANLASHGVGRSLHEEPAELSTWPDPSEKRVMTDGLVFTVEPFLSLGATWAEGGDDAWTLYADPKAPTVQYEHTVVATRN
GPVILTLPDGRA
>Mature_252_residues
MVIANDDELTKLKEIGRICANAIQVMAAAMEPGMTTLELDRIGRKVLEDSGARSAPEFCYQFPGATCISVNEEIAHGIPG
PRVIRAGDLVNIDVSAEKDGFFADTGASFAMPPVKPKIDKLCRDGKRALWVGLNQVKSGEPLAKIGTAVGAFAQKNRYTL
VANLASHGVGRSLHEEPAELSTWPDPSEKRVMTDGLVFTVEPFLSLGATWAEGGDDAWTLYADPKAPTVQYEHTVVATRN
GPVILTLPDGRA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=245, Percent_Identity=27.3469387755102, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI164420681, Length=244, Percent_Identity=28.6885245901639, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI1786364, Length=249, Percent_Identity=35.7429718875502, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71996291, Length=255, Percent_Identity=32.156862745098, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323273, Length=255, Percent_Identity=30.1960784313725, Blast_Score=125, Evalue=5e-30,
Organism=Drosophila melanogaster, GI21355531, Length=244, Percent_Identity=32.3770491803279, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24583427, Length=244, Percent_Identity=27.8688524590164, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27016; Mature: 27016

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIANDDELTKLKEIGRICANAIQVMAAAMEPGMTTLELDRIGRKVLEDSGARSAPEFCY
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCHHHH
QFPGATCISVNEEIAHGIPGPRVIRAGDLVNIDVSAEKDGFFADTGASFAMPPVKPKIDK
HCCCCEEEEECHHHHHCCCCCEEEECCCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHH
LCRDGKRALWVGLNQVKSGEPLAKIGTAVGAFAQKNRYTLVANLASHGVGRSLHEEPAEL
HHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHCCCCCC
STWPDPSEKRVMTDGLVFTVEPFLSLGATWAEGGDDAWTLYADPKAPTVQYEHTVVATRN
CCCCCCCCCEEEECCEEEEECHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEECC
GPVILTLPDGRA
CCEEEECCCCCC
>Mature Secondary Structure
MVIANDDELTKLKEIGRICANAIQVMAAAMEPGMTTLELDRIGRKVLEDSGARSAPEFCY
CEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCCHHHH
QFPGATCISVNEEIAHGIPGPRVIRAGDLVNIDVSAEKDGFFADTGASFAMPPVKPKIDK
HCCCCEEEEECHHHHHCCCCCEEEECCCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHH
LCRDGKRALWVGLNQVKSGEPLAKIGTAVGAFAQKNRYTLVANLASHGVGRSLHEEPAEL
HHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCCHHCCCCCC
STWPDPSEKRVMTDGLVFTVEPFLSLGATWAEGGDDAWTLYADPKAPTVQYEHTVVATRN
CCCCCCCCCEEEECCEEEEECHHHHCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEECC
GPVILTLPDGRA
CCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA