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The map label for this gene is mraW [H]

Identifier: 209550182

GI number: 209550182

Start: 2643802

End: 2644827

Strand: Reverse

Name: mraW [H]

Synonym: Rleg2_2602

Alternate gene names: 209550182

Gene position: 2644827-2643802 (Counterclockwise)

Preceding gene: 209550183

Following gene: 209550181

Centisome position: 58.28

GC content: 63.55

Gene sequence:

>1026_bases
ATGGTGGCGAATCCTGGCGGAGGTTCAACTGATGCCGGTGGCGGACCGGTTCGTCACATTCCTGTCCTTCTTGATGAAGT
GCTTTCGGCGCTGGCGCCCGCGCCCGGCAAGCTCATCCTTGATGGTACCTTCGGTGCTGGCGGTTACAGCTCAGCCATTC
TTGCGGCCGGCGCCGAGGTGATCGCGCTCGACCGCGATCCGACGGCGATTGCCTCCGGCCAGGCAATGGTCGCCGCCCAT
GGTGGCCGTCTCAAGCTCGTTCATTCGCAATTCTCACATCTTGCCGATCATGCGCCGCAAGGCGGGCTCGACGGTGTCGT
CCTCGATATCGGCGTTTCCTCGATGCAGATCGATGAGGCCGAGCGCGGTTTCTCTTTCCAGAAGAACGGGCCGCTCGACA
TGCGTATGTCGGCCGCAGGCGTTTCGGCCGCCGATGTCGTCAATCGCGCCAAGGTCGCCGATCTCATCCGCATCTTCCAT
TTCCTCGGTGAGGAAAGCCAGGCGCCGCGCATCGCGCATGCGATCGAGAAGCGTCGCGAGGAAAAGCCGTTCGAGACGAC
ACGCGATCTTGCCGGTCTCATCGAGCTGGTCACGCCCCGCAAGATGAAGGACAAGATCCATCCGGCAACGCGCGTCTTCC
AGGCCTTGCGCATCTTCGTCAATGACGAGCTCGGCGAACTCGCACAGGCGCTGTTTGCGGCGGAAGCGGCGCTGAAGCCG
GGCGGCCGGCTCGTCGTCGTCACCTTTCATTCGCTCGAAGACCGCATCGTCAAGAAATTCTTCTCCGACCGCGCCGGCAA
GGCGTCGGGGTCGCGGCATCTGCCGGTCGCGCATGAGCGGGCGGCAACTTTCGCGGCGATCGGCAAGCCGATGGTTTCGG
CAAGTGAGGCGGAGGCGGAGATCAATCCGCGCGCCCGTTCCGCCAAACTGCGCGCCGGCCTGAGGACGGAGGCCGCCGCT
GAAGCTGCGGATATGTCGCTCTTCGGGTTTCCCAATCTCGCCAGTCTCGGAAAGCTTGGAGGTTGA

Upstream 100 bases:

>100_bases
TTCAGCTTTGGCAGCCGCAGGCTTTTGTGGCTGCGCAGGCGCAGGCACGAGGGGAGCGCAAGCTGGCGGGCAAGCGTTCC
TGAAAGAACGAGGGAACGGA

Downstream 100 bases:

>100_bases
TATGCTGAAAACGTTCGATCTCGTGCTCATCGGCGTCATGACGGCCACCGCCGCCGTCACCTACACGATCAAGCATCGCG
CCGAATTGAAGCTCGAAGAG

Product: S-adenosyl-methyltransferase MraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MVANPGGGSTDAGGGPVRHIPVLLDEVLSALAPAPGKLILDGTFGAGGYSSAILAAGAEVIALDRDPTAIASGQAMVAAH
GGRLKLVHSQFSHLADHAPQGGLDGVVLDIGVSSMQIDEAERGFSFQKNGPLDMRMSAAGVSAADVVNRAKVADLIRIFH
FLGEESQAPRIAHAIEKRREEKPFETTRDLAGLIELVTPRKMKDKIHPATRVFQALRIFVNDELGELAQALFAAEAALKP
GGRLVVVTFHSLEDRIVKKFFSDRAGKASGSRHLPVAHERAATFAAIGKPMVSASEAEAEINPRARSAKLRAGLRTEAAA
EAADMSLFGFPNLASLGKLGG

Sequences:

>Translated_341_residues
MVANPGGGSTDAGGGPVRHIPVLLDEVLSALAPAPGKLILDGTFGAGGYSSAILAAGAEVIALDRDPTAIASGQAMVAAH
GGRLKLVHSQFSHLADHAPQGGLDGVVLDIGVSSMQIDEAERGFSFQKNGPLDMRMSAAGVSAADVVNRAKVADLIRIFH
FLGEESQAPRIAHAIEKRREEKPFETTRDLAGLIELVTPRKMKDKIHPATRVFQALRIFVNDELGELAQALFAAEAALKP
GGRLVVVTFHSLEDRIVKKFFSDRAGKASGSRHLPVAHERAATFAAIGKPMVSASEAEAEINPRARSAKLRAGLRTEAAA
EAADMSLFGFPNLASLGKLGG
>Mature_341_residues
MVANPGGGSTDAGGGPVRHIPVLLDEVLSALAPAPGKLILDGTFGAGGYSSAILAAGAEVIALDRDPTAIASGQAMVAAH
GGRLKLVHSQFSHLADHAPQGGLDGVVLDIGVSSMQIDEAERGFSFQKNGPLDMRMSAAGVSAADVVNRAKVADLIRIFH
FLGEESQAPRIAHAIEKRREEKPFETTRDLAGLIELVTPRKMKDKIHPATRVFQALRIFVNDELGELAQALFAAEAALKP
GGRLVVVTFHSLEDRIVKKFFSDRAGKASGSRHLPVAHERAATFAAIGKPMVSASEAEAEINPRARSAKLRAGLRTEAAA
EAADMSLFGFPNLASLGKLGG

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA [H]

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family [H]

Homologues:

Organism=Homo sapiens, GI165377209, Length=335, Percent_Identity=40.5970149253731, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI165377202, Length=187, Percent_Identity=41.1764705882353, Blast_Score=138, Evalue=9e-33,
Organism=Escherichia coli, GI1786270, Length=314, Percent_Identity=44.2675159235669, Blast_Score=230, Evalue=8e-62,
Organism=Drosophila melanogaster, GI62472493, Length=343, Percent_Identity=38.4839650145773, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28571637, Length=343, Percent_Identity=38.4839650145773, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002903 [H]

Pfam domain/function: PF01795 Methyltransf_5 [H]

EC number: NA

Molecular weight: Translated: 35723; Mature: 35723

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVANPGGGSTDAGGGPVRHIPVLLDEVLSALAPAPGKLILDGTFGAGGYSSAILAAGAEV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCEE
IALDRDPTAIASGQAMVAAHGGRLKLVHSQFSHLADHAPQGGLDGVVLDIGVSSMQIDEA
EEECCCCCHHCCCCEEEEECCCEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCHHEHHHH
ERGFSFQKNGPLDMRMSAAGVSAADVVNRAKVADLIRIFHFLGEESQAPRIAHAIEKRRE
HCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EKPFETTRDLAGLIELVTPRKMKDKIHPATRVFQALRIFVNDELGELAQALFAAEAALKP
CCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GGRLVVVTFHSLEDRIVKKFFSDRAGKASGSRHLPVAHERAATFAAIGKPMVSASEAEAE
CCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHCCCCCCCC
INPRARSAKLRAGLRTEAAAEAADMSLFGFPNLASLGKLGG
CCCCHHHHHHHHCCHHHHHHHHHCCEEECCCCHHHHCCCCC
>Mature Secondary Structure
MVANPGGGSTDAGGGPVRHIPVLLDEVLSALAPAPGKLILDGTFGAGGYSSAILAAGAEV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCCCEE
IALDRDPTAIASGQAMVAAHGGRLKLVHSQFSHLADHAPQGGLDGVVLDIGVSSMQIDEA
EEECCCCCHHCCCCEEEEECCCEEEEHHHHHHHHHHCCCCCCCCEEEEECCCCHHEHHHH
ERGFSFQKNGPLDMRMSAAGVSAADVVNRAKVADLIRIFHFLGEESQAPRIAHAIEKRRE
HCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
EKPFETTRDLAGLIELVTPRKMKDKIHPATRVFQALRIFVNDELGELAQALFAAEAALKP
CCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GGRLVVVTFHSLEDRIVKKFFSDRAGKASGSRHLPVAHERAATFAAIGKPMVSASEAEAE
CCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHCCCCCCCC
INPRARSAKLRAGLRTEAAAEAADMSLFGFPNLASLGKLGG
CCCCHHHHHHHHCCHHHHHHHHHCCEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA