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The map label for this gene is ftsA [H]

Identifier: 209550167

GI number: 209550167

Start: 2626103

End: 2627434

Strand: Reverse

Name: ftsA [H]

Synonym: Rleg2_2587

Alternate gene names: 209550167

Gene position: 2627434-2626103 (Counterclockwise)

Preceding gene: 209550168

Following gene: 209550166

Centisome position: 57.9

GC content: 65.17

Gene sequence:

>1332_bases
ATGAGCTTGTTCGGTTCATCCCATTTCGGATTGCCGCGCCTGAAGCCGCTTTCGTCGAAGCGGTCGCATGTCGTTTCGGT
GCTCGACATCGGCTCGACCAAGGTCGTCTGCATGATCGGCCGGCTGACGCCGCGCGAGGAAAGCCAGATCCTGCCGGGCC
GCACGCACAATATCGAGATCATCGGCATCGGGCACCAGCGTTCCCGCGGCATCAAGACCGGCGTGATCGCCGATCTCGAC
GCGCTGGAAGGCGTCATTCGCCTCGCCGTCGACGCGGCGGAGCGCATGGCCGGGCTGACCGTCGAGAGCCTGATCGTCAA
TCTGACGGCCGGCCGCCTCGGCAGCGACATTTACACAGCCACGATCGATCTCGGCGGCCAGGAAGTCGAACTCAACGATC
TGAAGAAGGTGCTGTCGGCCGCCTGCCAGCAGTCGCTGCGCCAGGACCGTTCGGTGCTGCATTCGCTGGCGACCGGCTTT
TCGCTCGACGGCGAGCGCGGCATCCGCGATCCGCTGGCAATGTATGGCGATGCGCTCGGGGTCGATATGCATGTGGTCAC
CGCAGAGCGCTCGGCGCTGAAGAACCTCGAGCTCAGCGTCAACCGCGCACATCTGTCGGTCGAGGGGATCGTCGCGACGC
CCTATGCATCGGGCCTTGCCGCTCTCGTCGATGACGAAGTCGAACTCGGCTGCGCGGCGATCGATATGGGCGGCGGCACC
ACGACGATCTCGGTCTTTGCCGAAGGCAAGCTCGTTCATACGGATGCCGTCGGCCTCGGCGGCCATCACGTGACCACCGA
TCTGGCGCGCGGCCTTTCGACCCGCATCGAGGATGCGGAGCGGCTGAAGGTCGTGCACGCCACGGCCCTTTCGAATTCCT
CCGACGAGCGCGAGCTGATCTCGATTCCGCCGATCGGCGAGGATGATCGCGACCAGCCGTCGCAGGTTCCGCGGGCGCTG
GTCTCGCGCATCGTTTCGGCCCGAATCGAAGAAACGATGGAACTGATCCGCGACCGCATCCAGCGCTCCGGCTTCAGCCC
GATCGTCGGCAAGCGCGTCGTGCTGACCGGCGGCGCGAGCCAGCTGACCGGCCTTGCCGATGTGGCGCGGCGCATTCTTG
CCCGCAACGTCCGCATCGGCCGTCCGATGGGCGTCTCGGGACTGCCGACGGCGGCCAAGGGCCCGGCTTTTTCGACGGCC
GTCGGCCTGATGATCTATCCGCAAGTCGCGGACATGGAGACACATGCGTCACAGAGCGGTCTGCTCATGTCGCTTGGTGG
AAATAACAGCCGCATAGCCCGGATGGGCCAGTGGCTGAAGGAAAGCTTCTGA

Upstream 100 bases:

>100_bases
CCGACAGAACCGCAATCCAGCTGACGCCGGAGGCGGCAGTCCGCCGTCAGACGGCTGTGACGGAGCGCACCAAGGAATTG
AAGAAGGCGGGGCAGAATAT

Downstream 100 bases:

>100_bases
AATTGAGTGATTGGCCGGCGTGGCGATGCGGCCAGAGAGAGAAGGAACAGGTACCATGACCATCAAGCTGCAAAAGCCTG
ACATCACAGAGCTGAAGCCG

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSLFGSSHFGLPRLKPLSSKRSHVVSVLDIGSTKVVCMIGRLTPREESQILPGRTHNIEIIGIGHQRSRGIKTGVIADLD
ALEGVIRLAVDAAERMAGLTVESLIVNLTAGRLGSDIYTATIDLGGQEVELNDLKKVLSAACQQSLRQDRSVLHSLATGF
SLDGERGIRDPLAMYGDALGVDMHVVTAERSALKNLELSVNRAHLSVEGIVATPYASGLAALVDDEVELGCAAIDMGGGT
TTISVFAEGKLVHTDAVGLGGHHVTTDLARGLSTRIEDAERLKVVHATALSNSSDERELISIPPIGEDDRDQPSQVPRAL
VSRIVSARIEETMELIRDRIQRSGFSPIVGKRVVLTGGASQLTGLADVARRILARNVRIGRPMGVSGLPTAAKGPAFSTA
VGLMIYPQVADMETHASQSGLLMSLGGNNSRIARMGQWLKESF

Sequences:

>Translated_443_residues
MSLFGSSHFGLPRLKPLSSKRSHVVSVLDIGSTKVVCMIGRLTPREESQILPGRTHNIEIIGIGHQRSRGIKTGVIADLD
ALEGVIRLAVDAAERMAGLTVESLIVNLTAGRLGSDIYTATIDLGGQEVELNDLKKVLSAACQQSLRQDRSVLHSLATGF
SLDGERGIRDPLAMYGDALGVDMHVVTAERSALKNLELSVNRAHLSVEGIVATPYASGLAALVDDEVELGCAAIDMGGGT
TTISVFAEGKLVHTDAVGLGGHHVTTDLARGLSTRIEDAERLKVVHATALSNSSDERELISIPPIGEDDRDQPSQVPRAL
VSRIVSARIEETMELIRDRIQRSGFSPIVGKRVVLTGGASQLTGLADVARRILARNVRIGRPMGVSGLPTAAKGPAFSTA
VGLMIYPQVADMETHASQSGLLMSLGGNNSRIARMGQWLKESF
>Mature_442_residues
SLFGSSHFGLPRLKPLSSKRSHVVSVLDIGSTKVVCMIGRLTPREESQILPGRTHNIEIIGIGHQRSRGIKTGVIADLDA
LEGVIRLAVDAAERMAGLTVESLIVNLTAGRLGSDIYTATIDLGGQEVELNDLKKVLSAACQQSLRQDRSVLHSLATGFS
LDGERGIRDPLAMYGDALGVDMHVVTAERSALKNLELSVNRAHLSVEGIVATPYASGLAALVDDEVELGCAAIDMGGGTT
TISVFAEGKLVHTDAVGLGGHHVTTDLARGLSTRIEDAERLKVVHATALSNSSDERELISIPPIGEDDRDQPSQVPRALV
SRIVSARIEETMELIRDRIQRSGFSPIVGKRVVLTGGASQLTGLADVARRILARNVRIGRPMGVSGLPTAAKGPAFSTAV
GLMIYPQVADMETHASQSGLLMSLGGNNSRIARMGQWLKESF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=424, Percent_Identity=29.7169811320755, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 47046; Mature: 46914

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFGSSHFGLPRLKPLSSKRSHVVSVLDIGSTKVVCMIGRLTPREESQILPGRTHNIEI
CCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEEE
IGIGHQRSRGIKTGVIADLDALEGVIRLAVDAAERMAGLTVESLIVNLTAGRLGSDIYTA
EEECCHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEE
TIDLGGQEVELNDLKKVLSAACQQSLRQDRSVLHSLATGFSLDGERGIRDPLAMYGDALG
EEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCC
VDMHVVTAERSALKNLELSVNRAHLSVEGIVATPYASGLAALVDDEVELGCAAIDMGGGT
CEEEEEECHHHHHHCCEEEEEEEEEEEEEEEECCCHHCHHHHHCCCHHCCEEEEECCCCC
TTISVFAEGKLVHTDAVGLGGHHVTTDLARGLSTRIEDAERLKVVHATALSNSSDERELI
EEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEHHCCCCCCCEEE
SIPPIGEDDRDQPSQVPRALVSRIVSARIEETMELIRDRIQRSGFSPIVGKRVVLTGGAS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHH
QLTGLADVARRILARNVRIGRPMGVSGLPTAAKGPAFSTAVGLMIYPQVADMETHASQSG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHEECEEEECCHHCCHHCCCCCC
LLMSLGGNNSRIARMGQWLKESF
EEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFGSSHFGLPRLKPLSSKRSHVVSVLDIGSTKVVCMIGRLTPREESQILPGRTHNIEI
CCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEEEE
IGIGHQRSRGIKTGVIADLDALEGVIRLAVDAAERMAGLTVESLIVNLTAGRLGSDIYTA
EEECCHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEE
TIDLGGQEVELNDLKKVLSAACQQSLRQDRSVLHSLATGFSLDGERGIRDPLAMYGDALG
EEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCC
VDMHVVTAERSALKNLELSVNRAHLSVEGIVATPYASGLAALVDDEVELGCAAIDMGGGT
CEEEEEECHHHHHHCCEEEEEEEEEEEEEEEECCCHHCHHHHHCCCHHCCEEEEECCCCC
TTISVFAEGKLVHTDAVGLGGHHVTTDLARGLSTRIEDAERLKVVHATALSNSSDERELI
EEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHEEEEEEHHCCCCCCCEEE
SIPPIGEDDRDQPSQVPRALVSRIVSARIEETMELIRDRIQRSGFSPIVGKRVVLTGGAS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHH
QLTGLADVARRILARNVRIGRPMGVSGLPTAAKGPAFSTAVGLMIYPQVADMETHASQSG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHEECEEEECCHHCCHHCCCCCC
LLMSLGGNNSRIARMGQWLKESF
EEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]