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The map label for this gene is lysN [H]

Identifier: 209550069

GI number: 209550069

Start: 2519723

End: 2520943

Strand: Reverse

Name: lysN [H]

Synonym: Rleg2_2486

Alternate gene names: 209550069

Gene position: 2520943-2519723 (Counterclockwise)

Preceding gene: 209550075

Following gene: 209550065

Centisome position: 55.55

GC content: 62.49

Gene sequence:

>1221_bases
ATGCTGAACTGGGACACCATGTTTGCGTCGCGCTCATCGCGCATGCGCGCATCCGAGATCCGCGAGCTTCTGAAGCTTCT
CGACCGGCCCGATATCATTTCCTTTGCCGGCGGCATCCCGGATCCGGCGCTGTTTCCCGATCAGGAATTCAAGCAGGCCT
ATGCCGACATCTTCGATGGTGCTGCCGTCAATTCGGCGCTGCAGTATTCGGTCAGCGAAGGCTACAAGCCGCTGCGCGAA
TGGCTGGTTGGGCAGATGGCCGATCTCGGCATCCCCTGCGAACTCGACAATGTCTTCATCGTCTCCGGCTCGCAGCAGGG
CCTCGATTATCTTGGCAAGCTGTTCCTCTCGCCGAACGATACCGCGCTCGCGACCTGGCCGACCTATCTTGGCGCGCTGC
AGGCCTTTAACGCCTATGAGCCGGCCTACGACCAGCTGACGCCGAACGGCAACCGAACGCCGGACTCCTACCGTGCGGCC
GCAGCCGCAGCCGGCGGCAAGGTGAAATTCGCCTATCTCTCCGCCGACTTCTCCAATCCGACCGGCGAAACGGTCGATCT
CGAGGGTCGCCGGAAGGTTTTGGCGCTGGCCGAAGAGCTCGACATCGCCGTCATCGAAGACGCTGCCTATCAGTCGCTGC
GTTACGACGGCGACCCGATCCCGCCGATCCTGGCGCTCGAGATCGCCGAAAAGGGCGACATCAACGATACGCGCACGATC
TATTGCGGCAGCTTCTCGAAGACGCTGGCGCCCGGCCTTCGTGTCGGCTTCATCGTCGCCAATGCTCCCGTCATCCGCAA
GCTGGTGCTGATGAAGCAGGCGGCCGACCTGCATTCCTCGACGATCAACCAGATGGCGATATCAGATGTCGCCGAGCGGG
GCTTCGAGGCCCAGGTCGCCAAGATCAAGGCCGCCTACATGAAGCGCCGCGACTGCATGCTGGCAGCGCTCGACAAATAT
ATGCCCGAAGGCACGAGCTGGACGAAGCCAGAAGGCGGCATGTTCATCTGGATCACGCTGCCGGAAGGCATGGAGGGGGC
CAAACTCTTGGCGAAATCGCTCGAAACCGCAAAGGTCGCCTTCGTGCCCGGCAAGGCCTTCTTCGCCGATGGTTCCGGCG
CCAACACTTTCCGCGTCAGCTTCTCCTGCGCCAACGAGCAGATGATCGAGGACGGCATCGGCCGCCTGGGCGCGCTGATC
TCGGCCGAGATCGGCGGCTGA

Upstream 100 bases:

>100_bases
GATTGCAACATGTCACCATGACAAGAAAATAGGTCAGTATTATTGACATAAATTTCCCGGCATGGTCTTCTGCCGGGAAT
AGAAAATACGAGGAAACCCC

Downstream 100 bases:

>100_bases
TTGTTGTAGGCAGGGGGAGACGTTGCCACGAGTCCCTTCTCCCCAGCGGGGAGAAGATGCCGGCAGGCAGATGAGGGGGT
TAGCGGCACAGCCGCGAATG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLNWDTMFASRSSRMRASEIRELLKLLDRPDIISFAGGIPDPALFPDQEFKQAYADIFDGAAVNSALQYSVSEGYKPLRE
WLVGQMADLGIPCELDNVFIVSGSQQGLDYLGKLFLSPNDTALATWPTYLGALQAFNAYEPAYDQLTPNGNRTPDSYRAA
AAAAGGKVKFAYLSADFSNPTGETVDLEGRRKVLALAEELDIAVIEDAAYQSLRYDGDPIPPILALEIAEKGDINDTRTI
YCGSFSKTLAPGLRVGFIVANAPVIRKLVLMKQAADLHSSTINQMAISDVAERGFEAQVAKIKAAYMKRRDCMLAALDKY
MPEGTSWTKPEGGMFIWITLPEGMEGAKLLAKSLETAKVAFVPGKAFFADGSGANTFRVSFSCANEQMIEDGIGRLGALI
SAEIGG

Sequences:

>Translated_406_residues
MLNWDTMFASRSSRMRASEIRELLKLLDRPDIISFAGGIPDPALFPDQEFKQAYADIFDGAAVNSALQYSVSEGYKPLRE
WLVGQMADLGIPCELDNVFIVSGSQQGLDYLGKLFLSPNDTALATWPTYLGALQAFNAYEPAYDQLTPNGNRTPDSYRAA
AAAAGGKVKFAYLSADFSNPTGETVDLEGRRKVLALAEELDIAVIEDAAYQSLRYDGDPIPPILALEIAEKGDINDTRTI
YCGSFSKTLAPGLRVGFIVANAPVIRKLVLMKQAADLHSSTINQMAISDVAERGFEAQVAKIKAAYMKRRDCMLAALDKY
MPEGTSWTKPEGGMFIWITLPEGMEGAKLLAKSLETAKVAFVPGKAFFADGSGANTFRVSFSCANEQMIEDGIGRLGALI
SAEIGG
>Mature_406_residues
MLNWDTMFASRSSRMRASEIRELLKLLDRPDIISFAGGIPDPALFPDQEFKQAYADIFDGAAVNSALQYSVSEGYKPLRE
WLVGQMADLGIPCELDNVFIVSGSQQGLDYLGKLFLSPNDTALATWPTYLGALQAFNAYEPAYDQLTPNGNRTPDSYRAA
AAAAGGKVKFAYLSADFSNPTGETVDLEGRRKVLALAEELDIAVIEDAAYQSLRYDGDPIPPILALEIAEKGDINDTRTI
YCGSFSKTLAPGLRVGFIVANAPVIRKLVLMKQAADLHSSTINQMAISDVAERGFEAQVAKIKAAYMKRRDCMLAALDKY
MPEGTSWTKPEGGMFIWITLPEGMEGAKLLAKSLETAKVAFVPGKAFFADGSGANTFRVSFSCANEQMIEDGIGRLGALI
SAEIGG

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=439, Percent_Identity=30.0683371298405, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI33469970, Length=439, Percent_Identity=30.0683371298405, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1787710, Length=389, Percent_Identity=26.2210796915167, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1790797, Length=389, Percent_Identity=26.7352185089974, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI48994949, Length=360, Percent_Identity=26.6666666666667, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=28.25, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321000, Length=254, Percent_Identity=32.6771653543307, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321236, Length=296, Percent_Identity=23.9864864864865, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21356535, Length=410, Percent_Identity=25.1219512195122, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43981; Mature: 43981

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNWDTMFASRSSRMRASEIRELLKLLDRPDIISFAGGIPDPALFPDQEFKQAYADIFDG
CCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEHHCCCCCCCCCCCCHHHHHHHHHHHCC
AAVNSALQYSVSEGYKPLREWLVGQMADLGIPCELDNVFIVSGSQQGLDYLGKLFLSPND
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHEECCCC
TALATWPTYLGALQAFNAYEPAYDQLTPNGNRTPDSYRAAAAAAGGKVKFAYLSADFSNP
CEEEEHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCC
TGETVDLEGRRKVLALAEELDIAVIEDAAYQSLRYDGDPIPPILALEIAEKGDINDTRTI
CCCEEECCCCHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEE
YCGSFSKTLAPGLRVGFIVANAPVIRKLVLMKQAADLHSSTINQMAISDVAERGFEAQVA
EECCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KIKAAYMKRRDCMLAALDKYMPEGTSWTKPEGGMFIWITLPEGMEGAKLLAKSLETAKVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEE
FVPGKAFFADGSGANTFRVSFSCANEQMIEDGIGRLGALISAEIGG
EECCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure
MLNWDTMFASRSSRMRASEIRELLKLLDRPDIISFAGGIPDPALFPDQEFKQAYADIFDG
CCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEHHCCCCCCCCCCCCHHHHHHHHHHHCC
AAVNSALQYSVSEGYKPLREWLVGQMADLGIPCELDNVFIVSGSQQGLDYLGKLFLSPND
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHEECCCC
TALATWPTYLGALQAFNAYEPAYDQLTPNGNRTPDSYRAAAAAAGGKVKFAYLSADFSNP
CEEEEHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCC
TGETVDLEGRRKVLALAEELDIAVIEDAAYQSLRYDGDPIPPILALEIAEKGDINDTRTI
CCCEEECCCCHHHHHHHHHCCEEEECHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCEE
YCGSFSKTLAPGLRVGFIVANAPVIRKLVLMKQAADLHSSTINQMAISDVAERGFEAQVA
EECCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KIKAAYMKRRDCMLAALDKYMPEGTSWTKPEGGMFIWITLPEGMEGAKLLAKSLETAKVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEE
FVPGKAFFADGSGANTFRVSFSCANEQMIEDGIGRLGALISAEIGG
EECCCEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA